ATE254934T1 - Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthält - Google Patents
Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthältInfo
- Publication number
- ATE254934T1 ATE254934T1 AT99923189T AT99923189T ATE254934T1 AT E254934 T1 ATE254934 T1 AT E254934T1 AT 99923189 T AT99923189 T AT 99923189T AT 99923189 T AT99923189 T AT 99923189T AT E254934 T1 ATE254934 T1 AT E254934T1
- Authority
- AT
- Austria
- Prior art keywords
- layer
- fibrinogen
- layers
- thrombin
- hemostatic bandage
- Prior art date
Links
- 108010049003 Fibrinogen Proteins 0.000 title abstract 2
- 102000008946 Fibrinogen Human genes 0.000 title abstract 2
- 108090000190 Thrombin Proteins 0.000 title abstract 2
- 229940012952 fibrinogen Drugs 0.000 title abstract 2
- 229960004072 thrombin Drugs 0.000 title abstract 2
- FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 title 1
- 230000002439 hemostatic effect Effects 0.000 title 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 2
- 229940030225 antihemorrhagics Drugs 0.000 abstract 2
- 230000000025 haemostatic effect Effects 0.000 abstract 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/225—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0042—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8593198P | 1998-05-19 | 1998-05-19 | |
| PCT/US1999/010952 WO1999059647A1 (en) | 1998-05-19 | 1999-05-19 | Hemostatic sandwich bandage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE254934T1 true ATE254934T1 (de) | 2003-12-15 |
Family
ID=22194926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99923189T ATE254934T1 (de) | 1998-05-19 | 1999-05-19 | Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthält |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0998311B1 (de) |
| JP (2) | JP4480270B2 (de) |
| AT (1) | ATE254934T1 (de) |
| AU (1) | AU755486B2 (de) |
| CA (1) | CA2295609C (de) |
| DE (1) | DE69913085T2 (de) |
| WO (1) | WO1999059647A1 (de) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020095157A1 (en) | 1999-07-23 | 2002-07-18 | Bowman Steven M. | Graft fixation device combination |
| CA2365376C (en) | 2000-12-21 | 2006-03-28 | Ethicon, Inc. | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
| US6733774B2 (en) | 2001-01-25 | 2004-05-11 | Nycomed Pharma As | Carrier with solid fibrinogen and solid thrombin |
| US7098315B2 (en) | 2001-01-25 | 2006-08-29 | Nycomed Pharma As | Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge |
| PL206197B1 (pl) * | 2001-01-25 | 2010-07-30 | Nycomed Pharma Asnycomed Pharma As | Sposób wytwarzania gąbki kolagenowej |
| US7052713B2 (en) | 2001-02-13 | 2006-05-30 | Nycomed Pharma As | Carrier with solid fibrinogen and solid thrombin |
| US6897348B2 (en) | 2001-12-19 | 2005-05-24 | Kimberly Clark Worldwide, Inc | Bandage, methods of producing and using same |
| US6967261B1 (en) | 2001-12-28 | 2005-11-22 | Kimberly-Clark Worldwide | Bandage, methods of producing and using same |
| US7745192B2 (en) * | 2002-04-03 | 2010-06-29 | Venomics Pty Limited | Prothrombin activating protein |
| AU2003236555B2 (en) * | 2002-07-01 | 2008-11-13 | Csl Limited | Hermeticaly sealed container for a haemostatic bandage |
| AUPS331002A0 (en) * | 2002-07-01 | 2002-07-25 | Csl Limited | A container |
| US7114617B2 (en) | 2002-07-02 | 2006-10-03 | Csl Limited | Container |
| AU2003270401B2 (en) | 2002-09-10 | 2008-03-13 | American National Red Cross | Hemostatic dressing |
| US20040078090A1 (en) | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
| CA2504812A1 (en) * | 2002-11-14 | 2004-05-27 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Thrombin-carrying bioabsorbable synthetic nonwoven fabric |
| EP1588722A4 (de) * | 2003-01-20 | 2011-03-02 | Chemo Sero Therapeut Res Inst | Hämostatische materialien |
| US8197837B2 (en) | 2003-03-07 | 2012-06-12 | Depuy Mitek, Inc. | Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof |
| US8226715B2 (en) | 2003-06-30 | 2012-07-24 | Depuy Mitek, Inc. | Scaffold for connective tissue repair |
| US10583220B2 (en) | 2003-08-11 | 2020-03-10 | DePuy Synthes Products, Inc. | Method and apparatus for resurfacing an articular surface |
| US7316822B2 (en) | 2003-11-26 | 2008-01-08 | Ethicon, Inc. | Conformable tissue repair implant capable of injection delivery |
| US7901461B2 (en) | 2003-12-05 | 2011-03-08 | Ethicon, Inc. | Viable tissue repair implants and methods of use |
| DE10361306A1 (de) * | 2003-12-24 | 2005-07-28 | Lts Lohmann Therapie-Systeme Ag | Wundauflage und Wundschnellverband mit einem vasokonstriktorischen Inhaltsstoff, sowie Herstellungsverfahren hierfür |
| US11395865B2 (en) | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
| US8221780B2 (en) | 2004-04-20 | 2012-07-17 | Depuy Mitek, Inc. | Nonwoven tissue scaffold |
| US8137686B2 (en) | 2004-04-20 | 2012-03-20 | Depuy Mitek, Inc. | Nonwoven tissue scaffold |
| US20070231372A1 (en) * | 2004-05-21 | 2007-10-04 | Juridical Foundation the Chemo-Sero- Therapeautic Research Institute | Tissue Sealant |
| WO2006033433A1 (ja) * | 2004-09-24 | 2006-03-30 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | 創傷治癒剤 |
| JP2006306759A (ja) * | 2005-04-27 | 2006-11-09 | Fujimori Kogyo Co Ltd | トロンビン医薬製剤 |
| US9474652B2 (en) * | 2006-01-09 | 2016-10-25 | Jack Mentkow | Hemostatic agent delivery system |
| US8277837B2 (en) | 2006-01-11 | 2012-10-02 | Entegrion, Inc. | Hemostatic textile |
| US20080033333A1 (en) * | 2006-08-04 | 2008-02-07 | Macphee Martin | Solid dressing for treating wounded tissue |
| MX2009006369A (es) | 2006-12-15 | 2010-02-24 | Lifebond Ltd | Apositos y selladores hemostaticos de gelatina-transglutaminasa. |
| EP2162283B1 (de) | 2007-06-14 | 2015-08-12 | Massachusetts Institute of Technology | Selbstaufbauende filme für protein- und arzneimittelabgabeanwendungen |
| DE102008034363A1 (de) | 2007-08-03 | 2009-02-05 | Birgit Riesinger | Wundpflegeartikel mit absorbierender Hülle |
| DE102008034364A1 (de) | 2007-08-03 | 2009-02-05 | Birgit Riesinger | Blutstillender Wundpflegeartikel |
| US10046081B2 (en) | 2008-04-11 | 2018-08-14 | The Henry M Jackson Foundation For The Advancement Of Military Medicine, Inc. | Electrospun dextran fibers and devices formed therefrom |
| AU2009236960A1 (en) | 2008-04-16 | 2009-10-22 | The Chemo-Sero-Therapeutic Research Institute | Method of producing thrombin-immobilized bioabsorbable sheet preparation |
| CN102124058B (zh) | 2008-06-18 | 2014-05-28 | 生命连结有限公司 | 改进的交联组合物 |
| WO2010102283A2 (en) | 2009-03-06 | 2010-09-10 | Jack Mentkow | Hemostatic agent composition, delivery system and method |
| US20120177718A1 (en) * | 2009-06-11 | 2012-07-12 | The Chemo-Sero-Therapeutic Research Institute | Wound-covering material |
| EP2477617B1 (de) | 2009-09-18 | 2018-01-31 | Bioinspire Technologies Inc. | Autonomes bioabbaubares pflaster |
| US9271925B2 (en) | 2013-03-11 | 2016-03-01 | Bioinspire Technologies, Inc. | Multi-layer biodegradable device having adjustable drug release profile |
| EP2515957B1 (de) | 2009-12-22 | 2015-07-29 | Lifebond Ltd | Modifizierung von enzymatischen vernetzern zur steuerung der eigenschaften vernetzter matrizen |
| DK2600910T3 (en) | 2010-08-05 | 2016-04-04 | Lifebond Ltd | Wound dressings and adhesives COMPREHENSIVE DRYING FORMATIONS |
| RU2455997C2 (ru) * | 2010-08-12 | 2012-07-20 | Государственное учреждение здравоохранения Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения | Способ лечения инфицированных ожоговых ран iiia степени |
| US9427360B2 (en) | 2010-11-04 | 2016-08-30 | W. Jerry Mezger | Hemostatic fabric |
| CA2834297A1 (en) * | 2011-04-27 | 2012-11-01 | Massachusetts Institute Of Technology | Coating compositions, methods and coated devices |
| US9561300B2 (en) | 2011-09-26 | 2017-02-07 | Yes, Inc. | Hemostatic compositions and dressings for bleeding |
| US20130096479A1 (en) | 2011-10-18 | 2013-04-18 | St. Teresa Medical, Inc. | Method of forming hemostatic products |
| US10278927B2 (en) | 2012-04-23 | 2019-05-07 | Massachusetts Institute Of Technology | Stable layer-by-layer coated particles |
| CA2873162C (en) | 2012-05-14 | 2021-07-27 | Teijin Limited | Formed sheet product and hemostatic material |
| WO2014134029A1 (en) | 2013-02-26 | 2014-09-04 | Massachusetts Institute Of Technology | Nucleic acid particles, methods and use thereof |
| WO2014150074A1 (en) | 2013-03-15 | 2014-09-25 | Massachusetts Institute Of Technology | Compositions and methods for nucleic acid delivery |
| DE102014104859A1 (de) | 2014-04-04 | 2015-10-08 | Universität Paderborn | Verfahren zur Beschichtung von Oberflächen durch enzymatische Reaktion |
| WO2017083050A1 (en) | 2015-11-12 | 2017-05-18 | St. Teresa Medical, Inc. | A method of sealing a durotomy |
| CN106620890A (zh) * | 2016-08-25 | 2017-05-10 | 泰安市御翔医疗科技有限公司 | 一种凝血酶缓释腔镜下止血夹及其制备方法 |
| IL247821A0 (en) * | 2016-09-14 | 2017-01-31 | Omrix Biopharmaceuticals Ltd | Adhesive preparations and their use |
| US11419947B2 (en) | 2017-10-30 | 2022-08-23 | Massachusetts Institute Of Technology | Layer-by-layer nanoparticles for cytokine therapy in cancer treatment |
| WO2019089717A1 (en) | 2017-11-02 | 2019-05-09 | St. Teresa Medical, Inc. | Fibrin sealant products |
| US11998654B2 (en) | 2018-07-12 | 2024-06-04 | Bard Shannon Limited | Securing implants and medical devices |
| EP3975841A1 (de) | 2019-05-30 | 2022-04-06 | Massachusetts Institute of Technology | Peptid-nukleinsäurefunktionalisierte hydrogelmikronadeln zur probenahme und detektion von nukleinsäuren in interstitieller flüssigkeit |
| US11885735B2 (en) | 2019-09-13 | 2024-01-30 | Ethicon, Inc. | Ex vivo and in vivo systems for evaluating hemostatic patches, sealants, adhesives on solid organs |
| ES2976086T3 (es) * | 2022-03-09 | 2024-07-23 | Octapharma Ag | Producto sanitario biodegradable no poroso, y métodos para fabricar y utilizar el mismo |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3212412C2 (de) * | 1982-04-02 | 1986-01-02 | Dr. Ruhland Nachf. GmbH, 8425 Neustadt | Gewebeverklebbare kollagene Wundauflage |
| DE3214337C2 (de) * | 1982-04-19 | 1984-04-26 | Serapharm - Michael Stroetmann, 4400 Münster | Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung |
| US5702715A (en) * | 1995-10-27 | 1997-12-30 | Drying Technology | Reinforced biological sealants |
| WO1997028832A1 (en) * | 1996-02-06 | 1997-08-14 | New Generation Medical Corporation | Composition for sealing wounds |
-
1999
- 1999-05-19 AT AT99923189T patent/ATE254934T1/de not_active IP Right Cessation
- 1999-05-19 JP JP2000549310A patent/JP4480270B2/ja not_active Expired - Fee Related
- 1999-05-19 AU AU40016/99A patent/AU755486B2/en not_active Ceased
- 1999-05-19 EP EP99923189A patent/EP0998311B1/de not_active Expired - Lifetime
- 1999-05-19 WO PCT/US1999/010952 patent/WO1999059647A1/en not_active Ceased
- 1999-05-19 DE DE69913085T patent/DE69913085T2/de not_active Expired - Lifetime
- 1999-05-19 CA CA002295609A patent/CA2295609C/en not_active Expired - Fee Related
-
2010
- 2010-01-05 JP JP2010000835A patent/JP2010115504A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010115504A (ja) | 2010-05-27 |
| JP4480270B2 (ja) | 2010-06-16 |
| WO1999059647A1 (en) | 1999-11-25 |
| EP0998311B1 (de) | 2003-11-26 |
| CA2295609C (en) | 2009-09-29 |
| EP0998311A1 (de) | 2000-05-10 |
| DE69913085D1 (de) | 2004-01-08 |
| AU4001699A (en) | 1999-12-06 |
| JP2002515300A (ja) | 2002-05-28 |
| CA2295609A1 (en) | 1999-11-25 |
| AU755486B2 (en) | 2002-12-12 |
| DE69913085T2 (de) | 2004-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |