ATE254934T1 - Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthält - Google Patents

Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthält

Info

Publication number
ATE254934T1
ATE254934T1 AT99923189T AT99923189T ATE254934T1 AT E254934 T1 ATE254934 T1 AT E254934T1 AT 99923189 T AT99923189 T AT 99923189T AT 99923189 T AT99923189 T AT 99923189T AT E254934 T1 ATE254934 T1 AT E254934T1
Authority
AT
Austria
Prior art keywords
layer
fibrinogen
layers
thrombin
hemostatic bandage
Prior art date
Application number
AT99923189T
Other languages
English (en)
Inventor
Martin J Macphee
William N Drohan
Dawson Beall
Stanley A Friedman
David Tuthill
Vladislav Bayer
Original Assignee
American Nat Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Nat Red Cross filed Critical American Nat Red Cross
Application granted granted Critical
Publication of ATE254934T1 publication Critical patent/ATE254934T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/64Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0042Fibrin; Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99923189T 1998-05-19 1999-05-19 Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthält ATE254934T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8593198P 1998-05-19 1998-05-19
PCT/US1999/010952 WO1999059647A1 (en) 1998-05-19 1999-05-19 Hemostatic sandwich bandage

Publications (1)

Publication Number Publication Date
ATE254934T1 true ATE254934T1 (de) 2003-12-15

Family

ID=22194926

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99923189T ATE254934T1 (de) 1998-05-19 1999-05-19 Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthält

Country Status (7)

Country Link
EP (1) EP0998311B1 (de)
JP (2) JP4480270B2 (de)
AT (1) ATE254934T1 (de)
AU (1) AU755486B2 (de)
CA (1) CA2295609C (de)
DE (1) DE69913085T2 (de)
WO (1) WO1999059647A1 (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020095157A1 (en) 1999-07-23 2002-07-18 Bowman Steven M. Graft fixation device combination
CA2365376C (en) 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US6733774B2 (en) 2001-01-25 2004-05-11 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
US7098315B2 (en) 2001-01-25 2006-08-29 Nycomed Pharma As Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge
PL206197B1 (pl) * 2001-01-25 2010-07-30 Nycomed Pharma Asnycomed Pharma As Sposób wytwarzania gąbki kolagenowej
US7052713B2 (en) 2001-02-13 2006-05-30 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
US6897348B2 (en) 2001-12-19 2005-05-24 Kimberly Clark Worldwide, Inc Bandage, methods of producing and using same
US6967261B1 (en) 2001-12-28 2005-11-22 Kimberly-Clark Worldwide Bandage, methods of producing and using same
US7745192B2 (en) * 2002-04-03 2010-06-29 Venomics Pty Limited Prothrombin activating protein
AU2003236555B2 (en) * 2002-07-01 2008-11-13 Csl Limited Hermeticaly sealed container for a haemostatic bandage
AUPS331002A0 (en) * 2002-07-01 2002-07-25 Csl Limited A container
US7114617B2 (en) 2002-07-02 2006-10-03 Csl Limited Container
AU2003270401B2 (en) 2002-09-10 2008-03-13 American National Red Cross Hemostatic dressing
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
CA2504812A1 (en) * 2002-11-14 2004-05-27 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Thrombin-carrying bioabsorbable synthetic nonwoven fabric
EP1588722A4 (de) * 2003-01-20 2011-03-02 Chemo Sero Therapeut Res Inst Hämostatische materialien
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
US7316822B2 (en) 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
US7901461B2 (en) 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
DE10361306A1 (de) * 2003-12-24 2005-07-28 Lts Lohmann Therapie-Systeme Ag Wundauflage und Wundschnellverband mit einem vasokonstriktorischen Inhaltsstoff, sowie Herstellungsverfahren hierfür
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
US8221780B2 (en) 2004-04-20 2012-07-17 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8137686B2 (en) 2004-04-20 2012-03-20 Depuy Mitek, Inc. Nonwoven tissue scaffold
US20070231372A1 (en) * 2004-05-21 2007-10-04 Juridical Foundation the Chemo-Sero- Therapeautic Research Institute Tissue Sealant
WO2006033433A1 (ja) * 2004-09-24 2006-03-30 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 創傷治癒剤
JP2006306759A (ja) * 2005-04-27 2006-11-09 Fujimori Kogyo Co Ltd トロンビン医薬製剤
US9474652B2 (en) * 2006-01-09 2016-10-25 Jack Mentkow Hemostatic agent delivery system
US8277837B2 (en) 2006-01-11 2012-10-02 Entegrion, Inc. Hemostatic textile
US20080033333A1 (en) * 2006-08-04 2008-02-07 Macphee Martin Solid dressing for treating wounded tissue
MX2009006369A (es) 2006-12-15 2010-02-24 Lifebond Ltd Apositos y selladores hemostaticos de gelatina-transglutaminasa.
EP2162283B1 (de) 2007-06-14 2015-08-12 Massachusetts Institute of Technology Selbstaufbauende filme für protein- und arzneimittelabgabeanwendungen
DE102008034363A1 (de) 2007-08-03 2009-02-05 Birgit Riesinger Wundpflegeartikel mit absorbierender Hülle
DE102008034364A1 (de) 2007-08-03 2009-02-05 Birgit Riesinger Blutstillender Wundpflegeartikel
US10046081B2 (en) 2008-04-11 2018-08-14 The Henry M Jackson Foundation For The Advancement Of Military Medicine, Inc. Electrospun dextran fibers and devices formed therefrom
AU2009236960A1 (en) 2008-04-16 2009-10-22 The Chemo-Sero-Therapeutic Research Institute Method of producing thrombin-immobilized bioabsorbable sheet preparation
CN102124058B (zh) 2008-06-18 2014-05-28 生命连结有限公司 改进的交联组合物
WO2010102283A2 (en) 2009-03-06 2010-09-10 Jack Mentkow Hemostatic agent composition, delivery system and method
US20120177718A1 (en) * 2009-06-11 2012-07-12 The Chemo-Sero-Therapeutic Research Institute Wound-covering material
EP2477617B1 (de) 2009-09-18 2018-01-31 Bioinspire Technologies Inc. Autonomes bioabbaubares pflaster
US9271925B2 (en) 2013-03-11 2016-03-01 Bioinspire Technologies, Inc. Multi-layer biodegradable device having adjustable drug release profile
EP2515957B1 (de) 2009-12-22 2015-07-29 Lifebond Ltd Modifizierung von enzymatischen vernetzern zur steuerung der eigenschaften vernetzter matrizen
DK2600910T3 (en) 2010-08-05 2016-04-04 Lifebond Ltd Wound dressings and adhesives COMPREHENSIVE DRYING FORMATIONS
RU2455997C2 (ru) * 2010-08-12 2012-07-20 Государственное учреждение здравоохранения Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения Способ лечения инфицированных ожоговых ран iiia степени
US9427360B2 (en) 2010-11-04 2016-08-30 W. Jerry Mezger Hemostatic fabric
CA2834297A1 (en) * 2011-04-27 2012-11-01 Massachusetts Institute Of Technology Coating compositions, methods and coated devices
US9561300B2 (en) 2011-09-26 2017-02-07 Yes, Inc. Hemostatic compositions and dressings for bleeding
US20130096479A1 (en) 2011-10-18 2013-04-18 St. Teresa Medical, Inc. Method of forming hemostatic products
US10278927B2 (en) 2012-04-23 2019-05-07 Massachusetts Institute Of Technology Stable layer-by-layer coated particles
CA2873162C (en) 2012-05-14 2021-07-27 Teijin Limited Formed sheet product and hemostatic material
WO2014134029A1 (en) 2013-02-26 2014-09-04 Massachusetts Institute Of Technology Nucleic acid particles, methods and use thereof
WO2014150074A1 (en) 2013-03-15 2014-09-25 Massachusetts Institute Of Technology Compositions and methods for nucleic acid delivery
DE102014104859A1 (de) 2014-04-04 2015-10-08 Universität Paderborn Verfahren zur Beschichtung von Oberflächen durch enzymatische Reaktion
WO2017083050A1 (en) 2015-11-12 2017-05-18 St. Teresa Medical, Inc. A method of sealing a durotomy
CN106620890A (zh) * 2016-08-25 2017-05-10 泰安市御翔医疗科技有限公司 一种凝血酶缓释腔镜下止血夹及其制备方法
IL247821A0 (en) * 2016-09-14 2017-01-31 Omrix Biopharmaceuticals Ltd Adhesive preparations and their use
US11419947B2 (en) 2017-10-30 2022-08-23 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
WO2019089717A1 (en) 2017-11-02 2019-05-09 St. Teresa Medical, Inc. Fibrin sealant products
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
EP3975841A1 (de) 2019-05-30 2022-04-06 Massachusetts Institute of Technology Peptid-nukleinsäurefunktionalisierte hydrogelmikronadeln zur probenahme und detektion von nukleinsäuren in interstitieller flüssigkeit
US11885735B2 (en) 2019-09-13 2024-01-30 Ethicon, Inc. Ex vivo and in vivo systems for evaluating hemostatic patches, sealants, adhesives on solid organs
ES2976086T3 (es) * 2022-03-09 2024-07-23 Octapharma Ag Producto sanitario biodegradable no poroso, y métodos para fabricar y utilizar el mismo

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3212412C2 (de) * 1982-04-02 1986-01-02 Dr. Ruhland Nachf. GmbH, 8425 Neustadt Gewebeverklebbare kollagene Wundauflage
DE3214337C2 (de) * 1982-04-19 1984-04-26 Serapharm - Michael Stroetmann, 4400 Münster Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung
US5702715A (en) * 1995-10-27 1997-12-30 Drying Technology Reinforced biological sealants
WO1997028832A1 (en) * 1996-02-06 1997-08-14 New Generation Medical Corporation Composition for sealing wounds

Also Published As

Publication number Publication date
JP2010115504A (ja) 2010-05-27
JP4480270B2 (ja) 2010-06-16
WO1999059647A1 (en) 1999-11-25
EP0998311B1 (de) 2003-11-26
CA2295609C (en) 2009-09-29
EP0998311A1 (de) 2000-05-10
DE69913085D1 (de) 2004-01-08
AU4001699A (en) 1999-12-06
JP2002515300A (ja) 2002-05-28
CA2295609A1 (en) 1999-11-25
AU755486B2 (en) 2002-12-12
DE69913085T2 (de) 2004-08-26

Similar Documents

Publication Publication Date Title
ATE254934T1 (de) Blutstillende mehrschichtige bandage, die eine thrombinschicht zwischen zwei fibrinogenschichten enthält
EP3727483B1 (de) Wundverband und verfahren zur herstellung davon
US6074663A (en) Method of using cross-linked fibrin material
Halfpenny et al. Comparison of 2 hemostatic agents for the prevention of postextraction hemorrhage in patients on anticoagulants
Alving et al. Fibrin sealant: summary of a conference on characteristics and clinical uses
KR100758137B1 (ko) 피브린을 기본으로 하는 유연성 창상 커버재의 제조방법
WO2008019128A3 (en) Solid dressing for treating wounded tissue
Fezza et al. The use of aerosolized fibrin glue in face-lift surgery
CA2498212A1 (en) Multi-layered hemostatic dressing comprising thrombin and fibrinogen
BR0304600A (pt) Curativo para ferimento e tecido hemostático e processos de produção e uso dos mesmos
ATE296069T1 (de) Resorbierbare mikromembrane zur verminderung von narbengewebe
DE3214337A1 (de) Resorbierbares flachmaterial zum abdichten und heilen von wunden und verfahren zu dessen herstellung
DE69231421D1 (de) Fibrin oder fibrinogen sowie biologisch abbaubare und biokompatible polymere enthaltende zusammensetzung zur gewebebehandlung
BRPI0516761A (pt) curativo hemostático de múltiplas camadas absorvìvel reforçado e método de produção do mesmo
DE69433939D1 (de) Hämostatisches pflaster
Yoon et al. Wound healing effect of regenerated oxidized cellulose versus fibrin sealant patch: an in vivo study
Vezeau Topical hemostatic agents: what the oral and maxillofacial surgeon needs to know
Schonauer et al. Topical hemostatic agents in neurosurgery, a comprehensive review: 15 years update
Miyamoto et al. The effects of sheet-type absorbable topical collagen hemostat used to prevent pulmonary fistula after lung surgery
Rahmani et al. Managing Local Bleeding in Dentoalveolar Surgery: Practical Techniques and Best Practices: A Narrative Review
ATE184199T1 (de) Verwendung von lokal appliziertem faktor xiii zur verhinderung von blutungen
Harfoush et al. Evaluation of topical application of platelet rich fibrin (PRF) in homeostasis of the bleeding after teeth extraction in patients taking warfarin
Demirjian et al. Disseminated intravascular coagulation in patients undergoing orthopedic surgery.
Revelli et al. Topical hemostatic agents
JPH0226984B2 (de)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties