ATE255591T1 - Mittel und verfahren zur verwendung in der hemmung des zelltods und zur verabreichung eines wirkstoffs in eine zelle - Google Patents

Mittel und verfahren zur verwendung in der hemmung des zelltods und zur verabreichung eines wirkstoffs in eine zelle

Info

Publication number
ATE255591T1
ATE255591T1 AT96915553T AT96915553T ATE255591T1 AT E255591 T1 ATE255591 T1 AT E255591T1 AT 96915553 T AT96915553 T AT 96915553T AT 96915553 T AT96915553 T AT 96915553T AT E255591 T1 ATE255591 T1 AT E255591T1
Authority
AT
Austria
Prior art keywords
administering
agent
cell
active substance
cell death
Prior art date
Application number
AT96915553T
Other languages
English (en)
Inventor
Anthony B Nesburn
Michael B Gorin
M Cristina Kenney
Ezra Maguen
Original Assignee
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Application granted granted Critical
Publication of ATE255591T1 publication Critical patent/ATE255591T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/102—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/004—Photosensitive materials
    • G03F7/038—Macromolecular compounds which are rendered insoluble or differentially wettable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyamides (AREA)
AT96915553T 1995-06-07 1996-05-07 Mittel und verfahren zur verwendung in der hemmung des zelltods und zur verabreichung eines wirkstoffs in eine zelle ATE255591T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/482,104 US5660692A (en) 1988-02-24 1995-06-07 Method of crosslinking amino acid-containing polymers using photoactivatable chemical crosslinkers
PCT/US1996/006418 WO1996040729A1 (en) 1995-06-07 1996-05-07 A method of cross-linking amino acid-containing polymers using photoactivatable chemical cross-linkers

Publications (1)

Publication Number Publication Date
ATE255591T1 true ATE255591T1 (de) 2003-12-15

Family

ID=23914678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96915553T ATE255591T1 (de) 1995-06-07 1996-05-07 Mittel und verfahren zur verwendung in der hemmung des zelltods und zur verabreichung eines wirkstoffs in eine zelle

Country Status (7)

Country Link
US (1) US5660692A (de)
EP (1) EP0832095B1 (de)
AT (1) ATE255591T1 (de)
CA (1) CA2222239A1 (de)
DE (1) DE69630954T2 (de)
ES (1) ES2210369T3 (de)
WO (1) WO1996040729A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6685965B1 (en) * 1997-10-22 2004-02-03 Industria E Comercio De Cosmeticos Natura Ltda. Process for stabilizing levogyre ascorbic acid (laa), a stable aqueous laa composition, a process for preparing a stable topical solution, an emulsion, a vitamin product, and a method for cosmetic, pharmaceutical or nutritional treatment
US20020188037A1 (en) * 1999-04-15 2002-12-12 Chudzik Stephen J. Method and system for providing bioactive agent release coating
AU760408B2 (en) 1998-04-27 2003-05-15 Surmodics, Inc. Bioactive agent release coating
US6197934B1 (en) 1998-05-22 2001-03-06 Collagenesis, Inc. Compound delivery using rapidly dissolving collagen film
US6165140A (en) 1998-12-28 2000-12-26 Micrus Corporation Composite guidewire
CA2361569A1 (en) * 1999-02-12 2000-08-17 Dale P. Devore Injectable collagen-based system for delivery of cells or therapeutic agents
US6887235B2 (en) 1999-03-24 2005-05-03 Micrus Corporation Variable stiffness heating catheter
US6352531B1 (en) 1999-03-24 2002-03-05 Micrus Corporation Variable stiffness optical fiber shaft
WO2000064371A1 (en) * 1999-04-27 2000-11-02 The Children's Hospital Of Philadelphia Stabilization of implantable bioprosthetic devices
WO2001092322A1 (fr) * 2000-05-26 2001-12-06 Coletica Utilisation de collagene d'origine aquatique pour la realisation de supports destines a l'ingenierie tissulaire, et supports et biomateriaux obtenus
US6335004B1 (en) 2000-05-31 2002-01-01 Ecolab Inc. Odorless phenolic compositions
US6838104B2 (en) * 2000-12-20 2005-01-04 Archer Daniels Midland Company Process for the production of tocotrienols
US20020177223A1 (en) * 2001-03-12 2002-11-28 Ogle Mathew F. Methods and compositions for crosslinking tissue
US7140874B2 (en) 2001-08-06 2006-11-28 Southwest Research Institute Method and apparatus for testing catalytic converter durability
AU2002351164A1 (en) * 2001-11-26 2003-06-10 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
JPWO2003094985A1 (ja) * 2002-05-14 2005-09-08 北海道ティー・エル・オー株式会社 人工細胞外マトリックス及びその製造方法
US7097850B2 (en) 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
CN1964748A (zh) 2004-04-06 2007-05-16 苏莫迪克斯公司 用于生物活性剂的涂料组合物
WO2006029571A1 (en) * 2004-09-14 2006-03-23 The University Of Hong Kong Photochemically crosslinked collagen scaffolds and methods for their preparation
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
EP1937796A2 (de) * 2005-07-20 2008-07-02 SurModics, Inc. Polymerbeschichtete nanofibrillenstrukturen und verfahren zur zellhaltung und -differenzierung
US7415991B2 (en) 2005-12-20 2008-08-26 Masco Corporation Of Indiana Faucet spout with water isolating couplings
US20090053290A1 (en) * 2006-03-08 2009-02-26 Sand Bruce J Transdermal drug delivery compositions and topical compositions for application on the skin
WO2007109134A2 (en) * 2006-03-17 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Intraocular lens implant
US8991425B2 (en) 2006-05-26 2015-03-31 Delta Faucet Company Waterway assembly including an overmolded support plate
US7766043B2 (en) 2006-05-26 2010-08-03 Masco Corporation Of Indiana Faucet including a molded waterway assembly
AU2007318210B2 (en) 2006-10-06 2014-02-20 Celularity Inc. Native (telopeptide) placental collagen compositions
US7748409B2 (en) 2007-01-31 2010-07-06 Masco Corporation Of Indiana Overmold interface for fluid carrying system
US7717133B2 (en) * 2007-01-31 2010-05-18 Masco Corporation Of Indiana Spout tip attachment
US7806141B2 (en) 2007-01-31 2010-10-05 Masco Corporation Of Indiana Mixing valve including a molded waterway assembly
WO2009097508A2 (en) * 2008-01-30 2009-08-06 Mcanulty, Jonathan Methods and compositions for wound healing
US9174839B2 (en) * 2008-01-30 2015-11-03 Imbed Biosciences, Inc. Methods and compositions for wound healing
WO2009126887A1 (en) 2008-04-10 2009-10-15 Masco Corporation Of Indiana Molded waterway for a two handle faucet
CN102076599B (zh) 2008-06-25 2014-10-08 印地安纳马斯科公司 具有可安装喷口的设于中心的龙头
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
EP2323670A4 (de) 2008-08-05 2013-12-25 Biomimedica Inc Polyurethan-gepfropfte hydrogele
US8104512B2 (en) 2008-09-25 2012-01-31 Masco Corporation Of Indiana Spout tip retention method
US20130217829A1 (en) 2010-08-27 2013-08-22 David Myung "hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same"
US8739826B2 (en) 2011-03-11 2014-06-03 Masco Corporation Of Indiana Centerset faucet body and method of making same
WO2013052105A2 (en) 2011-10-03 2013-04-11 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
AU2012340699A1 (en) 2011-11-21 2014-06-19 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
US8931500B2 (en) 2012-02-17 2015-01-13 Masco Corporation Of Indiana Two handle centerset faucet
US9974646B2 (en) 2012-09-05 2018-05-22 University Of Miami Keratoprosthesis, and system and method of corneal repair using same
EP3838280A1 (de) 2012-12-07 2021-06-23 Celularity Inc. Behandlung oraler läsionen mittels extrazellulärer plazentamatrix
NO2975611T3 (de) 2013-03-15 2018-06-09
JP2016526387A (ja) 2013-06-24 2016-09-05 アントフロゲネシス コーポレーション 細胞培養のための細胞外マトリクス組成物ビーズ
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
KR102899445B1 (ko) 2016-07-29 2025-12-15 임베드 바이오사이언시스 아이엔씨. 상처 치유를 위한 방법 및 조성물
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3152976A (en) * 1961-09-21 1964-10-13 Ethicon Inc Preparation of collagenous materials
JPS5785051A (en) * 1980-11-18 1982-05-27 Toppan Printing Co Ltd Water-soluble photosensitive material
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US4505855A (en) * 1982-09-30 1985-03-19 Massachusetts General Hospital Transparent non-fibrilized collagen material by ultracentrifugation
DE3248188A1 (de) * 1982-12-27 1984-06-28 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines kollagen-vlieses
US4511478A (en) * 1983-11-10 1985-04-16 Genetic Systems Corporation Polymerizable compounds and methods for preparing synthetic polymers that integrally contain polypeptides
MX163953B (es) * 1984-03-27 1992-07-03 Univ New Jersey Med Procedimiento para preparar una matriz biodegradable a base de colageno
US4597999A (en) * 1984-10-04 1986-07-01 The Hospital For Sick Children Method for coupling a hydrocarbon containing molecular species
JPS62246371A (ja) * 1986-04-19 1987-10-27 株式会社　高研 人工皮膚及びその製造方法
JPS62266064A (ja) * 1986-05-14 1987-11-18 株式会社　高研 コラ−ゲン膜の製造方法
US5024742A (en) * 1988-02-24 1991-06-18 Cedars-Sinai Medical Center Method of crosslinking amino acid containing polymers using photoactivatable chemical crosslinkers
FR2645870B1 (fr) * 1989-04-12 1993-01-22 Bioetica Sa Procede de reticulation du collagene par le diphenylphosphorylazide, collagene reticule ainsi obtenu et biomateriaux a base de collagene ainsi reticules
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
FR2679778B1 (fr) * 1991-08-02 1995-07-07 Coletica Utilisation de collagene reticule par un agent de reticulation pour la fabrication d'une membrane suturable, biocompatible, a resorption lente, ainsi qu'une telle membrane.
JP3532587B2 (ja) * 1993-04-23 2004-05-31 株式会社高研 架橋化タンパク質、その製造方法及びこれを用いた医用材料

Also Published As

Publication number Publication date
EP0832095B1 (de) 2003-12-03
ES2210369T3 (es) 2004-07-01
EP0832095A1 (de) 1998-04-01
CA2222239A1 (en) 1996-12-19
US5660692A (en) 1997-08-26
WO1996040729A1 (en) 1996-12-19
EP0832095A4 (de) 1999-07-21
DE69630954T2 (de) 2004-10-21
DE69630954D1 (de) 2004-01-15

Similar Documents

Publication Publication Date Title
DE69630954D1 (de) Mittel und verfahren zur verwendung in der hemmung des zelltods und zur verabreichung eines wirkstoffs in eine zelle
EP0330344A3 (de) Verfahren zur Vernetzung von Collagen mit chemischen photo-aktivierbaren Vernetzungsmitteln. Anwendungen der so vernetzten Collagen oder Aminosäure enthaltenden Polymere.
KR100589064B1 (ko) 상처 치료를 위한 기구 및 방법
US5552162A (en) Method for improvement of scar size and appearance
AU5056196A (en) Hydrogel-forming, self-solvating absorbable polyester copolymers and methods for use thereof
RS54114B1 (sr) Uređaj za isporuku riboflavina jontoforezom na rožnjaču za lečenje keratokonusa
DE69025943D1 (de) Verwendung von Spiperone-derivate zur Immunosuppression
ATE292493T1 (de) Vorrichtung zur intraokularen übertragung von aktiven wirkstoffen durch iontophorese
IL123290A (en) Iontophoretic device
ATE242960T1 (de) Vorrichtung und verfahren zur photoaktivierung
JPS6296417A (ja) 低級アルキル（ｃ１〜ｃ４）の極性溶媒と共にアミノ酸ポリマ−を含む持効性製剤
EP2922919B1 (de) Zusammensetzungen und verfahren zur reduzierung von oxidativen schäden
JPS63170320A (ja) 架橋したポリビニルピロリドンの無菌の水性ゲル
DE60008143D1 (de) Lipoxin-a4 und deren analoge zur behandlung von trockenen augen
ATE179888T1 (de) Ophthalmische zubereitung zur behandlung oder prävention von trockenem auge und krankheiten, die dadurch verursacht werden, enthaltend 12- sulfodehydroabietsäure
ATE220923T1 (de) Rekombinante adenoviren und deren verwendung in der gentherapie zur behandlung von augenerkrankungen
ATE411814T1 (de) Verfahren zur behandlung maligner zellen eines patienten und pharmazeutische zusammensetzung zu dessen anwendung
Kingsley et al. Topical substance P and corneal epithelial wound closure in the rabbit.
WO1995016435A3 (en) Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent
FR2757064B1 (fr) Lentille intraoculaire contenant un medicament relargable
RU2000101091A (ru) Способ лечения дистрофических заболеваний сетчатки и зрительного нерва
US20210085994A1 (en) Systems and methods for modulating cytokine activity
CA2483329C (en) Apparatus and methods for enzymatic escharotomy in burn induced compartment syndrome
KR20210093748A (ko) 흉터형성을 최소화하는 데에 사용하기 위한 신경독소
BRPI0416037A (pt) processos e dispositivos para tratamento de epitélio

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties