ATE255640T1 - Für die untereinheiten der 1,3-beta-d- glucansynthase kodierende dna - Google Patents

Für die untereinheiten der 1,3-beta-d- glucansynthase kodierende dna

Info

Publication number
ATE255640T1
ATE255640T1 AT94931333T AT94931333T ATE255640T1 AT E255640 T1 ATE255640 T1 AT E255640T1 AT 94931333 T AT94931333 T AT 94931333T AT 94931333 T AT94931333 T AT 94931333T AT E255640 T1 ATE255640 T1 AT E255640T1
Authority
AT
Austria
Prior art keywords
pct
dna molecules
beta
molecules
subunits
Prior art date
Application number
AT94931333T
Other languages
English (en)
Inventor
Cameron M Douglas
Joseph Clemas
Gary L Chrebet
Mohammed El-Sherbeini
Forrest Foor
Jennifer Nielsen Kahn
Rosemarie Kelly
Jean A Marrinan
Nancy R Morin
Janet C Onishi
Stephen Arthur Parent
Naasa M Ramadan
Gan-Ju Shei
Elizabeth A Register
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE255640T1 publication Critical patent/ATE255640T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT94931333T 1993-10-12 1994-10-11 Für die untereinheiten der 1,3-beta-d- glucansynthase kodierende dna ATE255640T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13514993A 1993-10-12 1993-10-12
US13514893A 1993-10-12 1993-10-12
US13515093A 1993-10-12 1993-10-12
PCT/US1994/011498 WO1995010625A1 (en) 1993-10-12 1994-10-11 Dna encoding 1,3-beta-d glucan synthase subunits

Publications (1)

Publication Number Publication Date
ATE255640T1 true ATE255640T1 (de) 2003-12-15

Family

ID=27384673

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94931333T ATE255640T1 (de) 1993-10-12 1994-10-11 Für die untereinheiten der 1,3-beta-d- glucansynthase kodierende dna

Country Status (8)

Country Link
US (1) US5821353A (de)
EP (1) EP0724644B1 (de)
JP (1) JP3664490B2 (de)
AT (1) ATE255640T1 (de)
CA (1) CA2173956C (de)
DE (1) DE69433385T2 (de)
ES (1) ES2210263T3 (de)
WO (1) WO1995010625A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484724A (en) * 1994-05-26 1996-01-16 Merck & Co., Inc. DNA encoding GLSI
US6117641A (en) 1996-04-11 2000-09-12 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents and uses related thereto
JP2001513622A (ja) 1996-04-11 2001-09-04 マイトティックス インコーポレーテッド 抗菌剤の同定のためのアッセイおよび試薬、並びにそれらに関連する利用
US6727082B1 (en) 1996-04-11 2004-04-27 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
US6280963B1 (en) * 1997-11-07 2001-08-28 Millennium Pharmaceuticals, Inc. Essential fungal genes and their use
CA2218446A1 (en) 1997-12-12 1999-06-12 Mcgill University New candida albicans kre9 and uses thereof
CA2255140A1 (en) * 1997-12-23 1999-06-23 Eli Lilly And Company Echinocandin binding domain of 1,3-.beta.-glucan synthase
US6783985B1 (en) 2000-02-18 2004-08-31 Elitra Pharmaceuticals Inc. Gene disruption methodologies for drug target discovery
US20030180953A1 (en) * 2000-12-29 2003-09-25 Elitra Pharmaceuticals, Inc. Gene disruption methodologies for drug target discovery
EP1390468A4 (de) * 2001-04-23 2004-09-22 Elitra Pharmaceuticals Inc Identifizierung essentieller gene von aspergillus fumigatus und verwendungsverfahren
US7022481B2 (en) * 2002-12-19 2006-04-04 Rosetta Inpharmatics Llc Methods of using glucan synthase pathway reporter genes to screen for antifungal compounds
JP5319281B2 (ja) * 2005-07-26 2013-10-16 ユニバーシティ オブ メディシン アンド デンティストリー オブ ニュージャージー エキノカンジン系薬物に対する耐性の分析法並びに同分析法のためのオリゴヌクレオチド・セット及び試薬キット
US20150086982A1 (en) * 2011-08-19 2015-03-26 Roka Bioscience, Inc. Compositions and methods for detecting and discriminating between yeast or mold

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194600A (en) * 1990-03-05 1993-03-16 Royal Institute For The Advancement Of Learning Genes which participate in β-glucan assembly and use thereof

Also Published As

Publication number Publication date
EP0724644A4 (de) 2001-07-04
ES2210263T3 (es) 2004-07-01
EP0724644B1 (de) 2003-12-03
JPH09504431A (ja) 1997-05-06
DE69433385T2 (de) 2004-09-16
WO1995010625A1 (en) 1995-04-20
US5821353A (en) 1998-10-13
EP0724644A1 (de) 1996-08-07
CA2173956A1 (en) 1995-04-20
CA2173956C (en) 2008-10-07
JP3664490B2 (ja) 2005-06-29
DE69433385D1 (de) 2004-01-15

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