ATE256145T1 - Peptid analoge, die einen siebengliedrigen lactamring enthalten - Google Patents

Peptid analoge, die einen siebengliedrigen lactamring enthalten

Info

Publication number
ATE256145T1
ATE256145T1 AT97945015T AT97945015T ATE256145T1 AT E256145 T1 ATE256145 T1 AT E256145T1 AT 97945015 T AT97945015 T AT 97945015T AT 97945015 T AT97945015 T AT 97945015T AT E256145 T1 ATE256145 T1 AT E256145T1
Authority
AT
Austria
Prior art keywords
peptide derivatives
membed
lactam ring
peptide analogues
analogues containing
Prior art date
Application number
AT97945015T
Other languages
English (en)
Inventor
Richard William Arthur Luke
Ronald Cotton
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE256145T1 publication Critical patent/ATE256145T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97945015T 1996-10-19 1997-10-14 Peptid analoge, die einen siebengliedrigen lactamring enthalten ATE256145T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9621836.7A GB9621836D0 (en) 1996-10-19 1996-10-19 Peptide compounds
PCT/GB1997/002837 WO1998017680A1 (en) 1996-10-19 1997-10-14 Peptide analogues containing a 7-membered lactam ring

Publications (1)

Publication Number Publication Date
ATE256145T1 true ATE256145T1 (de) 2003-12-15

Family

ID=10801703

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97945015T ATE256145T1 (de) 1996-10-19 1997-10-14 Peptid analoge, die einen siebengliedrigen lactamring enthalten

Country Status (10)

Country Link
US (1) US6207644B1 (de)
EP (1) EP0932618B1 (de)
JP (1) JP2001508036A (de)
AT (1) ATE256145T1 (de)
AU (1) AU4633097A (de)
DE (1) DE69726743T2 (de)
GB (1) GB9621836D0 (de)
TW (1) TW492868B (de)
WO (1) WO1998017680A1 (de)
ZA (1) ZA979338B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ332347A (en) * 1996-06-07 2000-05-26 Zeneca Ltd Peptide derivatives containing a hydrophobic group, L-amino acid residues and modified L-amino acid residues
US7840278B1 (en) 1999-06-25 2010-11-23 Puskas John D Devices and methods for vagus nerve stimulation
US7201940B1 (en) 2001-06-12 2007-04-10 Advanced Cardiovascular Systems, Inc. Method and apparatus for thermal spray processing of medical devices
TW200502221A (en) 2002-10-03 2005-01-16 Astrazeneca Ab Novel lactams and uses thereof
PL211458B1 (pl) 2003-02-14 2012-05-31 Provid Pharmaceuticals Związki, kompozycja farmaceutyczna zawierająca je oraz zastosowanie związków
EP1636196A1 (de) 2003-03-14 2006-03-22 AstraZeneca AB Neue lactame und ihre verwendung
CA2547651C (en) * 2003-12-01 2015-06-23 Cambridge University Technical Services Limited Anti-inflammatory agents
EP2229399A1 (de) * 2007-12-03 2010-09-22 Provid Pharmaceuticals, Inc. Inhibitoren der antigenpräsentation durch mhc-klasse-ii-moleküle und verfahren zu deren anwendung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474778A (en) 1983-11-09 1984-10-02 E. R. Squibb & Sons, Inc. Lactam containing compounds, their pharmaceutical compositions and method of use
DE3711335A1 (de) 1987-04-03 1988-10-20 Merck Patent Gmbh Aminosaeurederivate
US5223485A (en) 1989-01-31 1993-06-29 Abbott Laboratories Anaphylatoxin-receptor ligands
WO1992002543A1 (en) * 1990-08-01 1992-02-20 Cytel Corporation Novel immunosuppressant peptides
DE4034829A1 (de) 1990-11-02 1992-05-07 Merck Patent Gmbh Cyclopeptide
AU2468392A (en) 1991-08-29 1993-04-05 Cytel Corporation Novel immunosuppressants
ES2122145T3 (es) * 1993-06-04 1998-12-16 Vertex Pharma Fosfiniloximetil-cetonas peptidicas como inhibidores de la enzima convertida de la interleuquina-1 beta.
JP3926839B2 (ja) 1993-09-14 2007-06-06 エピミューン，インコーポレイティド 万能ｄｒ−結合性ペプチドを用いる免疫応答の改変
CA2186873A1 (en) 1994-04-01 1995-10-12 Charles J. Hackett Haptenated peptides and uses thereof
AU713530B2 (en) 1995-03-24 1999-12-02 Molecumetics, Ltd. Beta-sheet mimetics and use thereof as protease inhibitors
US5840835A (en) * 1995-10-30 1998-11-24 Merck & Co., Inc. Inhibitors of peptide binding to MHC class II proteins
AU7604196A (en) 1995-10-30 1997-05-22 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5719296A (en) 1995-10-30 1998-02-17 Merck & Co., Inc. Pseudopeptide lactam inhibitors of peptide binding to MHC class II proteins
US5817757A (en) * 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
GB9702377D0 (en) * 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives

Also Published As

Publication number Publication date
DE69726743T2 (de) 2004-10-14
US6207644B1 (en) 2001-03-27
EP0932618B1 (de) 2003-12-10
WO1998017680A1 (en) 1998-04-30
DE69726743D1 (de) 2004-01-22
GB9621836D0 (en) 1996-12-11
AU4633097A (en) 1998-05-15
TW492868B (en) 2002-07-01
ZA979338B (en) 1998-04-20
EP0932618A1 (de) 1999-08-04
JP2001508036A (ja) 2001-06-19

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties