ATE256497T1 - Verfahren zur mikroverkapselung und elektrostatische behandlung - Google Patents

Verfahren zur mikroverkapselung und elektrostatische behandlung

Info

Publication number
ATE256497T1
ATE256497T1 AT99923047T AT99923047T ATE256497T1 AT E256497 T1 ATE256497 T1 AT E256497T1 AT 99923047 T AT99923047 T AT 99923047T AT 99923047 T AT99923047 T AT 99923047T AT E256497 T1 ATE256497 T1 AT E256497T1
Authority
AT
Austria
Prior art keywords
microcapsules
methods
forming
hydrophilic
hydrophobic
Prior art date
Application number
AT99923047T
Other languages
English (en)
Inventor
Dennis R Morrison
Benjamin Mosier
Original Assignee
Nasa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nasa filed Critical Nasa
Application granted granted Critical
Publication of ATE256497T1 publication Critical patent/ATE256497T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Physical Vapour Deposition (AREA)
AT99923047T 1998-05-15 1999-05-14 Verfahren zur mikroverkapselung und elektrostatische behandlung ATE256497T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/079,770 US6103271A (en) 1994-12-02 1998-05-15 Microencapsulation and electrostatic processing method
PCT/US1999/010654 WO1999059714A1 (en) 1998-05-15 1999-05-14 Microencapsulation and electrostatic processing method

Publications (1)

Publication Number Publication Date
ATE256497T1 true ATE256497T1 (de) 2004-01-15

Family

ID=22152707

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99923047T ATE256497T1 (de) 1998-05-15 1999-05-14 Verfahren zur mikroverkapselung und elektrostatische behandlung

Country Status (6)

Country Link
US (1) US6103271A (de)
EP (1) EP1079918B1 (de)
AT (1) ATE256497T1 (de)
DE (1) DE69913685T2 (de)
ES (1) ES2214028T3 (de)
WO (1) WO1999059714A1 (de)

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KR100541753B1 (ko) * 1999-07-27 2006-01-10 가부시키가이샤 시세이도 마이크로캡슐 및 그 제조방법
EP1267914B2 (de) * 2000-02-04 2013-11-06 Children's Hospital Research Foundation Verwendung von lysosomal acid lipase zur behandlung von atherosklerose und ähnlichen krankheiten
JP2003528701A (ja) * 2000-04-03 2003-09-30 バテル メモリアル インスティチュート 定量吐出装置および液体配合物
PT2283818T (pt) 2000-11-30 2017-10-09 Vectura Ltd Método de preparação de partículas para utilização numa composição farmacêutica
PT1337239E (pt) 2000-11-30 2010-01-26 Vectura Ltd Partículas servindo à preparação de uma composição farmacêutica
WO2002043750A2 (en) * 2000-12-01 2002-06-06 Battelle Memorial Institute Method for the stabilizing of biomolecules (e.g. insulin) in liquid formulations
US20050156340A1 (en) 2004-01-20 2005-07-21 E Ink Corporation Preparation of capsules
US6890592B2 (en) 2002-03-13 2005-05-10 Appleton Papers Inc. Uniform microcapsules
DE10217557A1 (de) * 2002-04-19 2003-11-06 Degussa Bioactives Gmbh Funktionsnahrungsmittel enthaltend eine Phospholipid-haltige stabile Matrix
US20050232996A1 (en) * 2002-04-19 2005-10-20 Dirk Cremer Matrix comprising a bioactive component containing phospholipid
US6958848B2 (en) * 2002-05-23 2005-10-25 E Ink Corporation Capsules, materials for use therein and electrophoretic media and displays containing such capsules
US20050058689A1 (en) 2003-07-03 2005-03-17 Reactive Surfaces, Ltd. Antifungal paints and coatings
FR2850040B1 (fr) * 2003-01-20 2005-03-11 Centre Nat Rech Scient Systemes pour microencapsulation et leurs applications
WO2004103510A2 (en) * 2003-05-14 2004-12-02 The Regents Of The University Of Colorado Methods and apparatus using electrostatic atomization to form liquid vesicles
US7101617B2 (en) 2003-07-10 2006-09-05 Motorola, Inc. Silicone dispensing with a conformal film
US7094045B2 (en) * 2003-12-09 2006-08-22 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microencapsulation system and method
US7182810B2 (en) * 2004-04-16 2007-02-27 Canadian Space Agency Protein temperature evaporation-controlled crystallization device and method thereof
WO2005122734A2 (en) * 2004-06-14 2005-12-29 The Research Foundation Of State University Of New York Nanosphere/microsphere delivery system for the treatment of spinal cord injury
EP1627911A1 (de) 2004-08-20 2006-02-22 Schering Aktiengesellschaft Waschvorrichtung
US20060037634A1 (en) * 2004-08-20 2006-02-23 Vorholz Jessica F Washing apparatus
US20060071357A1 (en) * 2004-09-27 2006-04-06 Pilon Laurent G Method and apparatus for liquid microencapsulation with polymers using ultrasonic atomization
US20060147536A1 (en) * 2004-12-30 2006-07-06 Fiore Robert A Method for removing fluids containing dissolved or suspended carbohydrates, lipids, metals, salts, and/or toxins from biological systems
US20090297496A1 (en) * 2005-09-08 2009-12-03 Childrens Hospital Medical Center Lysosomal Acid Lipase Therapy for NAFLD and Related Diseases
US7341986B1 (en) * 2006-02-03 2008-03-11 Murtie Nina Kalusha Cleaning concentrate consisting of extra virgin olive oil and isopropyl alcohol
US20080187487A1 (en) * 2006-05-03 2008-08-07 Gustavo Larsen Methods for producing multilayered particles, fibers and sprays and methods for administering the same
US7985058B2 (en) * 2007-01-12 2011-07-26 Mark Gray Method and apparatus for making uniformly sized particles
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
JP2011068884A (ja) * 2009-08-31 2011-04-07 Sanyo Chem Ind Ltd シリコンインゴットスライス用水溶性切削液
US9022950B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
WO2014058945A1 (en) 2012-10-11 2014-04-17 Bullington Gregory J Systems and methods for delivering a fluid to a patient with reduced contamination
ES2481940B1 (es) * 2012-12-17 2015-05-06 Universidade De Santiago De Compostela Nanocápsulas de protamina
EP3920801A1 (de) 2019-02-08 2021-12-15 Magnolia Medical Technologies, Inc. Vorrichtungen und verfahren zur sammlung und verteilung von körperflüssigkeiten
CN112439540B (zh) * 2019-08-30 2022-08-30 中国石油天然气股份有限公司 一种轻重矿物分离装置及方法

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JPS5719662A (en) * 1980-07-09 1982-02-01 Fuji Photo Film Co Ltd Preparation of microcapsule reagent for immune reaction
JPS57110332A (en) * 1980-12-13 1982-07-09 Kanzaki Paper Mfg Co Ltd Preparation of microcapsule
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US4619795A (en) * 1984-12-24 1986-10-28 Technicon Instruments Corp. Method for preparing lipid vesicles
US4936901A (en) * 1986-07-09 1990-06-26 Monsanto Company Formulations of water-dispersible granules and process for preparation thereof
US4909933A (en) * 1988-09-15 1990-03-20 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Apparatus for mixing solutions in low gravity environments
US5165994A (en) * 1990-06-05 1992-11-24 University Of Delaware Spontaneous equilbrium surfactant vesicles
US5545423A (en) * 1991-11-25 1996-08-13 Vivorx, Inc. Cytoprotective, biocompatible, retrievable macrocapsule containment systems for biologically active materials
US5827531A (en) * 1994-12-02 1998-10-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microcapsules and methods for making
US5702182A (en) * 1996-07-24 1997-12-30 Instrumentation Technology Associates, Inc. Apparatus for mixing selected volumes of liquids

Also Published As

Publication number Publication date
EP1079918B1 (de) 2003-12-17
DE69913685T2 (de) 2004-10-07
EP1079918A1 (de) 2001-03-07
WO1999059714A1 (en) 1999-11-25
US6103271A (en) 2000-08-15
ES2214028T3 (es) 2004-09-01
DE69913685D1 (de) 2004-01-29

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