ATE256751T1 - Monoklonaler anti-hiv antikörper - Google Patents

Monoklonaler anti-hiv antikörper

Info

Publication number
ATE256751T1
ATE256751T1 AT94909286T AT94909286T ATE256751T1 AT E256751 T1 ATE256751 T1 AT E256751T1 AT 94909286 T AT94909286 T AT 94909286T AT 94909286 T AT94909286 T AT 94909286T AT E256751 T1 ATE256751 T1 AT E256751T1
Authority
AT
Austria
Prior art keywords
region
antibody
hiv
pnd
monoclonal antibody
Prior art date
Application number
AT94909286T
Other languages
English (en)
Inventor
Yasuyuki Eda
Hiroaki Maeda
Keiichi Makizumi
Kouichi Shiosaki
Kiyoshi Osatomi
Kazuhiko Kimachi
Hirofumi Higuchi
Sachio Tokiyoshi
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of ATE256751T1 publication Critical patent/ATE256751T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94909286T 1993-03-11 1994-03-09 Monoklonaler anti-hiv antikörper ATE256751T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7891393 1993-03-11
PCT/JP1994/000371 WO1994020632A1 (fr) 1993-03-11 1994-03-09 Anticorps monoclonal dirige contre le vih

Publications (1)

Publication Number Publication Date
ATE256751T1 true ATE256751T1 (de) 2004-01-15

Family

ID=13675093

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909286T ATE256751T1 (de) 1993-03-11 1994-03-09 Monoklonaler anti-hiv antikörper

Country Status (11)

Country Link
US (1) US6114143A (de)
EP (1) EP0690132B1 (de)
JP (1) JP3855071B2 (de)
KR (1) KR100337069B1 (de)
AT (1) ATE256751T1 (de)
AU (1) AU681633B2 (de)
DE (1) DE69433422T2 (de)
DK (1) DK0690132T3 (de)
ES (1) ES2213148T3 (de)
PT (1) PT690132E (de)
WO (1) WO1994020632A1 (de)

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KR100423614B1 (ko) * 2001-05-16 2004-03-22 주식회사유한양행 비형간염바이러스의 에스-표면항원을 인식하는단일클론항체의 가변영역 및 이를 코딩하는 유전자
RU2305111C2 (ru) 2001-09-25 2007-08-27 Джуридикэл Фаундейшн Дзе Чемо-Серо-Терапьютик Рисерч Инститьют Рекомбинантное антитело против остеопонтина и его применение
US7195768B2 (en) * 2001-11-07 2007-03-27 Duke University Polyvalent immunogen
AU2002363436A1 (en) 2001-11-07 2003-05-19 Duke University Polyvalent immunogen of hiv
US7172761B2 (en) * 2001-11-07 2007-02-06 Duke University Polyvalent immunogen
US7041499B2 (en) * 2001-12-12 2006-05-09 University Of North Texas Health Science Center Immuno activation of CS1 receptor in natural killer cells to inhibit tumor cell growth
WO2003087215A1 (en) * 2002-04-12 2003-10-23 Mba Polymers, Inc. Compositions of materials containing recycled plastics
WO2003091275A2 (en) * 2002-04-23 2003-11-06 Andrea Savarino Compositions containing anti-hiv peptides and methods of use
EP1595959B1 (de) * 2003-02-20 2015-01-21 The Chemo-Sero-Therapeutic Research Institute Verfahren zur verstärkung der wirksamkeit eines präparats von monoklonalem antikörper
US20050014230A1 (en) * 2003-07-16 2005-01-20 Ccl Holding Co., Ltd. Preparation of fully human antibodies
US7807157B2 (en) 2004-02-20 2010-10-05 Intellect Neurosciences Inc. Monoclonal antibodies and use thereof
US8202523B2 (en) * 2005-09-22 2012-06-19 ProSci, Inc. Glycosylated polypeptides produced in yeast mutants and methods of use thereof
EP2025749B8 (de) 2006-05-31 2012-05-23 Astellas Pharma Inc. Humanisierter anti-human-osteopontin-antikörper
JP5440179B2 (ja) 2008-01-11 2014-03-12 アステラス製薬株式会社 改良型ヒト化抗ヒトα９インテグリン抗体
EP2376122A2 (de) 2009-01-12 2011-10-19 Takeda Pharmaceutical Company Limited Wirkstoff zur prophylaxe oder behandlung von krebs
WO2011111838A1 (ja) 2010-03-11 2011-09-15 株式会社資生堂 アオウキクサ由来の新規リポキシゲナーゼ
CA2793959C (en) 2010-03-25 2019-06-04 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
WO2011125785A1 (ja) 2010-03-31 2011-10-13 株式会社資生堂 アオウキクサ由来の新規アレンオキサイドシンターゼ
TW201249867A (en) 2011-04-01 2012-12-16 Astellas Pharma Inc Novel anti-human il-23 receptor antibody
AU2012255266B2 (en) 2011-05-17 2017-05-25 California Institute Of Technology Human immunodeficiency virus neutralizing antibodies and methods of use thereof
DK2691530T3 (en) 2011-06-10 2018-05-22 Univ Oregon Health & Science CMV GLYCOPROTEIN AND RECOMBINANT VECTORS
PT2743348T (pt) * 2011-08-11 2018-02-23 Astellas Pharma Inc Novo anticorpo anti-ngf humano
EP2568289A3 (de) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunselektion von rekombinantem vesikulärem Stomatitisvirus mit Expression von HIV-1-Proteinen durch Breitbandneutralisierungs-Antikörper
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
MX345019B (es) 2011-12-22 2017-01-11 Astellas Pharma Inc Nuevo anticuerpo ctgf antihumano.
WO2013129454A1 (ja) 2012-02-28 2013-09-06 アステラス製薬株式会社 新規抗ヒトｉｌ－２３受容体抗体
EP2679596B1 (de) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 Env-proteinvariante
ES2730978T3 (es) 2013-08-09 2019-11-13 Astellas Pharma Inc Anticuerpo anti-receptor de TSLP humana nuevo
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
CN114292331A (zh) 2013-12-24 2022-04-08 安斯泰来制药株式会社 抗人bdca-2抗体、其生产方法、多核苷酸、表达载体、宿主细胞及医药组合物
EP3069730A3 (de) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
EP3072901A1 (de) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
US9925258B2 (en) 2015-10-02 2018-03-27 International Aids Vaccine Initiative Replication-competent VSV-HIV Env vaccines
CR20200653A (es) 2018-07-03 2021-02-11 Gilead Sciences Inc Anticuerpos que se dirigen al gp120 de vih y métodos de uso
US20220017618A1 (en) 2018-08-20 2022-01-20 Jiangsu Hengrui Medicine Co., Ltd. Use of tim-3 antibody in preparation of medicines for treating tumors
CA3118073A1 (en) * 2018-10-29 2020-05-07 Immuno-Biological Laboratories Co., Ltd. Anti-hiv antibody and method for producing same
IL282650B2 (en) 2018-10-31 2024-09-01 Astellas Pharma Inc Anti-human fn14 antibody
KR20250153805A (ko) 2023-02-27 2025-10-27 쑤저우 선카디아 바이오파마수티컬즈 컴퍼니 리미티드 항-dll3 항체, 이의 항체-약물 접합체 및 이의 의약적 용도
EP4696711A1 (de) 2023-04-13 2026-02-18 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Antigenbindendes molekül mit spezifischer bindung an egfr und muc1, wirkstoffkonjugat davon und medizinische verwendung davon
WO2024251255A1 (zh) 2023-06-08 2024-12-12 江苏恒瑞医药股份有限公司 抗npr1抗体及其医药用途

Family Cites Families (6)

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GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
DE3853779T2 (de) * 1987-05-29 1995-09-07 Baylor College Medicine Hiv-1 neutralisierende monoklonale antikörper.
EP0339504A3 (de) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Menschliches immunoinsuffizientes Virus (HIV) env-codiertes Peptid, welches im Stande ist, die HIV hemmenden Antikörper bei Säugetieren hervorzurufen
KR900701836A (ko) * 1988-10-03 1990-12-04 라메쉬 엘. 라탄 신규 hiv 단백질 및 aids의 진단, 예방 또는 치료에 유용한 펩티드
AU6036690A (en) * 1989-06-05 1991-01-07 Helen F. Carson Human monoclonal antibodies to hiv-1mn gp 120
EP0554446B1 (de) * 1991-08-22 1998-11-04 Nissin Shokuhin Kabushiki Kaisha In der Therapie von einer HIV-1-Infektion verwendbare monoklonale Antikörper

Also Published As

Publication number Publication date
KR100337069B1 (ko) 2002-10-11
JP3855071B2 (ja) 2006-12-06
US6114143A (en) 2000-09-05
KR960701214A (ko) 1996-02-24
DE69433422D1 (de) 2004-01-29
ES2213148T3 (es) 2004-08-16
AU6219494A (en) 1994-09-26
EP0690132A4 (de) 1998-07-29
WO1994020632A1 (fr) 1994-09-15
DE69433422T2 (de) 2004-09-16
PT690132E (pt) 2004-04-30
EP0690132A1 (de) 1996-01-03
DK0690132T3 (da) 2004-04-13
EP0690132B1 (de) 2003-12-17
AU681633B2 (en) 1997-09-04

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