ATE257708T1 - Kombinationen enthaltend vx478, zidovudin und 3tc zur behandlung von hiv - Google Patents

Kombinationen enthaltend vx478, zidovudin und 3tc zur behandlung von hiv

Info

Publication number: ATE257708T1
Authority: AT; Austria
Prior art keywords: zidovudine; hiv; treatment; combinations containing; combinations
Prior art date: 1996-06-25

Application number

AT97928263T

Other languages

English (en)

Inventor

Clair Martha St

David Walter Barry

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-25

Filing date

1997-06-23

Publication date

2004-01-15

1996-07-04 Priority claimed from GBGB9614022.3A external-priority patent/GB9614022D0/en

1997-06-23 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2004-01-15 Application granted granted Critical

2004-01-15 Publication of ATE257708T1 publication Critical patent/ATE257708T1/de

Links

HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 title 1
229960002555 zidovudine Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

AT97928263T 1996-06-25 1997-06-23 Kombinationen enthaltend vx478, zidovudin und 3tc zur behandlung von hiv ATE257708T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US2054396P	1996-06-25	1996-06-25
US2102796P	1996-07-02	1996-07-02
GBGB9614022.3A GB9614022D0 (en)	1996-07-04	1996-07-04	Antiviral therapeutic combinations
PCT/EP1997/003247 WO1997049411A1 (en)	1996-06-25	1997-06-23	Combinations comprising vx478, zidovudine, ftc and/or 3tc for use in the treatment of hiv

Publications (1)

Publication Number	Publication Date
ATE257708T1 true ATE257708T1 (de)	2004-01-15

Family

ID=27268358

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97928263T ATE257708T1 (de)	1996-06-25	1997-06-23	Kombinationen enthaltend vx478, zidovudin und 3tc zur behandlung von hiv

Country Status (26)

Country	Link
US (1)	US6544961B1 (de)
EP (1)	EP0938321B1 (de)
JP (1)	JP2000515852A (de)
KR (1)	KR20000022226A (de)
CN (1)	CN1228026A (de)
AP (1)	AP9801419A0 (de)
AT (1)	ATE257708T1 (de)
AU (1)	AU727983B2 (de)
BR (1)	BR9709939A (de)
CA (1)	CA2258956A1 (de)
CO (1)	CO4900074A1 (de)
CZ (1)	CZ429498A3 (de)
DE (1)	DE69727240T2 (de)
EA (1)	EA001517B1 (de)
ES (1)	ES2213217T3 (de)
HU (1)	HUP9903249A3 (de)
ID (1)	ID19490A (de)
IL (1)	IL127351A0 (de)
IS (1)	IS4915A (de)
NO (1)	NO986034L (de)
NZ (1)	NZ333099A (de)
PL (1)	PL330747A1 (de)
TR (1)	TR199802704T2 (de)
TW (1)	TW469132B (de)
WO (1)	WO1997049411A1 (de)
YU (1)	YU58398A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY115461A (en)	1995-03-30	2003-06-30	Wellcome Found	Synergistic combinations of zidovudine, 1592u89 and 3tc
CA2374198A1 (en) *	1998-05-29	1999-12-02	Maki Arai	Combination therapy for treatment of fiv infection
US6875773B1 (en)	1998-05-29	2005-04-05	Ben M. Dunn	Combination therapy for treatment of FIV infection
GB0011903D0 (en) *	2000-05-18	2000-07-05	Astrazeneca Ab	Combination chemotherapy
CN101123957B (zh) *	2005-02-01	2010-12-08	特罗伊卡药品有限公司	双氯芬酸及其药学上可接受盐的注射剂
ES2279707B1 (es) *	2005-11-10	2008-06-01	Combino Pharm, S.L.	Formulaciones orales que comprenden 3'-azidonucleosidos.
US8178564B2 (en) *	2006-11-06	2012-05-15	Poniard Pharmaceuticals, Inc.	Use of picoplatin to treat colorectal cancer
US8168661B2 (en) *	2006-11-06	2012-05-01	Poniard Pharmaceuticals, Inc.	Use of picoplatin to treat colorectal cancer
US8168662B1 (en)	2006-11-06	2012-05-01	Poniard Pharmaceuticals, Inc.	Use of picoplatin to treat colorectal cancer
US8173686B2 (en)	2006-11-06	2012-05-08	Poniard Pharmaceuticals, Inc.	Use of picoplatin to treat colorectal cancer
US20110033528A1 (en) *	2009-08-05	2011-02-10	Poniard Pharmaceuticals, Inc.	Stabilized picoplatin oral dosage form
US20100260832A1 (en) *	2007-06-27	2010-10-14	Poniard Pharmaceuticals, Inc.	Combination therapy for ovarian cancer
TW200916094A (en) *	2007-06-27	2009-04-16	Poniard Pharmaceuticals Inc	Stabilized picoplatin dosage form
WO2009011861A1 (en) *	2007-07-16	2009-01-22	Poniard Pharmaceuticals, Inc.	Oral formulations for picoplatin
EP2249644A4 (de) *	2008-02-08	2012-05-30	Poniard Pharmaceuticals Inc	Picoplatin und amrubicin zur behandlung von lungenkrebs
UA105556C2 (uk) *	2010-01-27	2014-05-26	Віів Гелскер Компані	Комбінація сполук, що містить інгібітори віл інтегрази з іншими терапевтичними агентами

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4724232A (en) *	1985-03-16	1988-02-09	Burroughs Wellcome Co.	Treatment of human viral infections
US5047407A (en)	1989-02-08	1991-09-10	Iaf Biochem International, Inc.	2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
MY104575A (en)	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.
US5204466A (en)	1990-02-01	1993-04-20	Emory University	Method and compositions for the synthesis of bch-189 and related compounds
GB9009861D0 (en)	1990-05-02	1990-06-27	Glaxo Group Ltd	Chemical compounds
IL100502A (en)	1991-01-03	1995-12-08	Iaf Biochem Int	PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
IL100965A (en) *	1991-02-22	1999-12-31	Univ Emory	2-Hydroxymethyl-5-(5-fluorocytosin-l-yl)-1,3-oxathiolane its resolution and pharmaceutical compositions containing it
GB9104740D0 (en) *	1991-03-06	1991-04-17	Wellcome Found	Antiviral nucleoside combination
DE69206876T3 (de)	1991-05-16	2004-08-12	Glaxo Group Ltd., Greenford	Nukleosidanalogen enthaltende Antiviren-Zubereitungen
GB9111902D0 (en)	1991-06-03	1991-07-24	Glaxo Group Ltd	Chemical compounds
GB9307013D0 (en) *	1993-04-02	1993-05-26	Wellcome Found	Therapeutic combinations
JP3657002B2 (ja)	1992-08-25	2005-06-08	ジー．ディー．サールアンドカンパニー	レトロウイルスプロテアーゼ阻害剤として有用なα−およびβ−アミノ酸ヒドロキシエチルアミノスルホンアミド
IS2334B (is) *	1992-09-08	2008-02-15	Vertex Pharmaceuticals Inc., (A Massachusetts Corporation)	Aspartyl próteasi hemjari af nýjum flokki súlfonamíða
US5723490A (en) *	1992-09-08	1998-03-03	Vertex Pharmaceuticals Incorporated	THF-containing sulfonamide inhibitors of aspartyl protease
UA49803C2 (uk) *	1994-06-03	2002-10-15	Дж.Д. Сьорль Енд Ко	Спосіб лікування ретровірусних інфекцій
GB9503850D0 (en)	1995-02-25	1995-04-19	Glaxo Group Ltd	Medicaments
US5869461A (en)	1995-03-16	1999-02-09	Yale University	Reducing toxicity of L-nucleosides with D-nucleosides
MY115461A (en)	1995-03-30	2003-06-30	Wellcome Found	Synergistic combinations of zidovudine, 1592u89 and 3tc
US5646180A (en) *	1995-12-05	1997-07-08	Vertex Pharmaceuticals Incorporated	Treatment of the CNS effects of HIV
TW536403B (en)	1997-03-24	2003-06-11	Glaxo Group Ltd	An ethanol and ethylenediaminetetraacetic acid free pharmaceutical composition comprising lamivudine and exhibiting antimicrobial preservative efficacy

1997
- 1997-06-23 WO PCT/EP1997/003247 patent/WO1997049411A1/en not_active Ceased
- 1997-06-23 CO CO97034781A patent/CO4900074A1/es unknown
- 1997-06-23 PL PL97330747A patent/PL330747A1/xx unknown
- 1997-06-23 EP EP97928263A patent/EP0938321B1/de not_active Expired - Lifetime
- 1997-06-23 DE DE69727240T patent/DE69727240T2/de not_active Expired - Fee Related
- 1997-06-23 CN CN97197357A patent/CN1228026A/zh active Pending
- 1997-06-23 ID IDP972147A patent/ID19490A/id unknown
- 1997-06-23 NZ NZ333099A patent/NZ333099A/en unknown
- 1997-06-23 US US09/202,660 patent/US6544961B1/en not_active Expired - Fee Related
- 1997-06-23 CZ CZ984294A patent/CZ429498A3/cs unknown
- 1997-06-23 CA CA002258956A patent/CA2258956A1/en not_active Abandoned
- 1997-06-23 AP APAP/P/1998/001419A patent/AP9801419A0/en unknown
- 1997-06-23 HU HU9903249A patent/HUP9903249A3/hu unknown
- 1997-06-23 AU AU32627/97A patent/AU727983B2/en not_active Ceased
- 1997-06-23 TR TR1998/02704T patent/TR199802704T2/xx unknown
- 1997-06-23 EA EA199801045A patent/EA001517B1/ru not_active IP Right Cessation
- 1997-06-23 AT AT97928263T patent/ATE257708T1/de not_active IP Right Cessation
- 1997-06-23 KR KR1019980710646A patent/KR20000022226A/ko not_active Withdrawn
- 1997-06-23 BR BR9709939A patent/BR9709939A/pt unknown
- 1997-06-23 JP JP10502320A patent/JP2000515852A/ja not_active Ceased
- 1997-06-23 IL IL12735197A patent/IL127351A0/xx unknown
- 1997-06-23 ES ES97928263T patent/ES2213217T3/es not_active Expired - Lifetime
- 1997-08-05 TW TW086111193A patent/TW469132B/zh active
1998
- 1998-11-30 IS IS4915A patent/IS4915A/is unknown
- 1998-12-16 YU YU58398A patent/YU58398A/sr unknown
- 1998-12-22 NO NO986034A patent/NO986034L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EA001517B1 (ru)	2001-04-23
DE69727240T2 (de)	2004-11-25
PL330747A1 (en)	1999-05-24
DE69727240D1 (de)	2004-02-19
KR20000022226A (ko)	2000-04-25
CN1228026A (zh)	1999-09-08
EA199801045A1 (ru)	1999-08-26
EP0938321B1 (de)	2004-01-14
TW469132B (en)	2001-12-21
NO986034D0 (no)	1998-12-22
BR9709939A (pt)	1999-08-10
AU727983B2 (en)	2001-01-04
HUP9903249A3 (en)	2001-04-28
ID19490A (id)	1998-07-16
HUP9903249A2 (hu)	2000-10-28
CZ429498A3 (cs)	1999-06-16
JP2000515852A (ja)	2000-11-28
ES2213217T3 (es)	2004-08-16
IS4915A (is)	1998-11-30
CA2258956A1 (en)	1997-12-31
TR199802704T2 (xx)	1999-03-22
NZ333099A (en)	2000-06-23
CO4900074A1 (es)	2000-03-27
YU58398A (en)	1999-11-22
EP0938321A1 (de)	1999-09-01
NO986034L (no)	1999-02-23
WO1997049411A1 (en)	1997-12-31
US6544961B1 (en)	2003-04-08
AP9801419A0 (en)	1998-12-31
AU3262797A (en)	1998-01-14
IL127351A0 (en)	1999-10-28

Legal Events

Date	Code	Title	Description
2004-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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DE69729817D1 (de)	2004-08-19	Behandlung von Aldehyd-fixierten Geweben
DE69727240D1 (de)	2004-02-19	Kombinationen enthaltend vx478, zidovudin und 3tc zur behandlung von hiv
DE69711311D1 (de)	2002-05-02	Vorrichtung zur thermischen Behandlung von Gewebe
DE69812784D1 (de)	2003-05-08	Zusammensetzung zur Vorbeugung und Beseitigung von Pflanzenkrankheiten
DE69019345D1 (de)	1995-06-14	Zusammensetzung zur behandlung von samen.
DE69405919D1 (de)	1997-11-06	Zusammensetzungen zur Behandlung von Keratinfasern
DE3850433D1 (de)	1994-08-04	Allergiebehandlung und Zusammensetzung dafür.
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DE69825319D1 (de)	2004-09-02	Präparat zur vorbeugung und behandlung von entzündungen
DE69926485D1 (de)	2005-09-08	Behandlung von durchblasgasen
DE69519602D1 (de)	2001-01-18	Kugelförmige Aktivkohle zur Behandlung von Hämorrhoiden
NO992504D0 (no)	1999-05-25	Sammensetninger for behandling av jord, fremgangsmÕte for fremstilling derav, samt anvendelse
DE69814993D1 (de)	2003-07-03	Quasi-azeotrope Mischungen auf Basis von 1,1,1,3,3,-Pentafluorobutan, Methylene Chloride und Methanol zur Behandlung von festen Oberflächen