ATE258069T1 - Verfahren zur herstellung von iodierten oranischen röntgenkontrastmitteln - Google Patents
Verfahren zur herstellung von iodierten oranischen röntgenkontrastmittelnInfo
- Publication number
- ATE258069T1 ATE258069T1 AT97913322T AT97913322T ATE258069T1 AT E258069 T1 ATE258069 T1 AT E258069T1 AT 97913322 T AT97913322 T AT 97913322T AT 97913322 T AT97913322 T AT 97913322T AT E258069 T1 ATE258069 T1 AT E258069T1
- Authority
- AT
- Austria
- Prior art keywords
- oranic
- contrast agents
- ray contrast
- iodinated
- producing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Spectrometry And Color Measurement (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9624612.9A GB9624612D0 (en) | 1996-11-26 | 1996-11-26 | Process |
| PCT/GB1997/003205 WO1998023296A1 (en) | 1996-11-26 | 1997-11-21 | Process for the production of iodinated organic x-ray contrast agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258069T1 true ATE258069T1 (de) | 2004-02-15 |
Family
ID=10803533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97913322T ATE258069T1 (de) | 1996-11-26 | 1997-11-21 | Verfahren zur herstellung von iodierten oranischen röntgenkontrastmitteln |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6232499B1 (de) |
| EP (1) | EP0941129B1 (de) |
| JP (1) | JP4360474B2 (de) |
| CN (1) | CN1139404C (de) |
| AT (1) | ATE258069T1 (de) |
| AU (1) | AU5062298A (de) |
| CA (1) | CA2272296A1 (de) |
| CZ (1) | CZ297113B6 (de) |
| DE (1) | DE69727311T2 (de) |
| GB (1) | GB9624612D0 (de) |
| NO (1) | NO315896B1 (de) |
| WO (1) | WO1998023296A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6300633B1 (en) | 1998-07-06 | 2001-10-09 | Bayer Corporation | In-line method for determining the residue content of an isocyanate and apparatus useful therefor |
| GB9903109D0 (en) * | 1999-02-11 | 1999-04-07 | Nycomed Imaging As | Process |
| US20050203578A1 (en) * | 2001-08-15 | 2005-09-15 | Weiner Michael L. | Process and apparatus for treating biological organisms |
| JP4787679B2 (ja) * | 2005-08-17 | 2011-10-05 | 武田薬品工業株式会社 | 化合物の結晶化過程のモニター方法および結晶の製造方法 |
| EP1966110B1 (de) | 2005-12-19 | 2013-04-24 | Ge Healthcare As | Verfahren zur aufreinigung von iodixanol |
| US20110021832A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | Synthesis of iodixanol in water |
| US7999135B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using ultrasound |
| US7999134B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using milling |
| US8969619B2 (en) | 2009-07-21 | 2015-03-03 | Ge Healthcare As | Synthesis of iodixanol in propyleneglycol |
| US8962886B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in methanol |
| US8962887B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol |
| KR101699226B1 (ko) | 2009-11-26 | 2017-01-24 | 호비온 차이나 홀딩 리미티드 | 이오딕사놀의 제조 및 정제 |
| JP5848621B2 (ja) * | 2012-01-25 | 2016-01-27 | 浜松ホトニクス株式会社 | 薬物評価方法及び薬物評価装置 |
| MX354604B (es) | 2012-09-27 | 2018-03-07 | Ge Healthcare As | Preparacion de un compuesto intermediario de ioforminol. |
| CN104768921A (zh) | 2012-11-12 | 2015-07-08 | 通用电气医疗集团股份有限公司 | X-射线造影剂中间体的制备 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608189A5 (de) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
| US4640833A (en) * | 1983-02-28 | 1987-02-03 | Adamantech, Inc. | Use of perfluorobromoalkyl ethers as X-ray contrast agents |
| FI78617C (fi) * | 1983-02-28 | 1989-09-11 | Childrens Hosp Medical Center | Roentgenkontrastmedel. |
| US5191119A (en) * | 1983-10-20 | 1993-03-02 | Cook Imaging Corp. | Process for producing non-ionic radiographic contrast media utilizing N-allylation |
| FR2625506B1 (fr) * | 1987-12-31 | 1992-02-21 | Bp Chimie Sa | Procede et appareillage de fabrication de polymeres controlee a l'aide d'un systeme de regulation comprenant un spectrophotometre infrarouge |
| US4963745A (en) * | 1989-09-01 | 1990-10-16 | Ashland Oil, Inc. | Octane measuring process and device |
| US5349188A (en) * | 1990-04-09 | 1994-09-20 | Ashland Oil, Inc. | Near infrared analysis of piano constituents and octane number of hydrocarbons |
| US5686061A (en) * | 1994-04-11 | 1997-11-11 | The Board Of Regents Of The University Of Texas System | Particulate contrast media derived from non-ionic water soluble contrast agents for CT enhancement of hepatic tumors |
| US5573952A (en) * | 1994-08-12 | 1996-11-12 | E. I. Du Pont De Nemours And Company | Process for controlling concentration of a solution of a solvent and polymer |
| US6596904B1 (en) * | 1996-01-29 | 2003-07-22 | Mallinc Krodt Inc | Process for producing ioversol |
-
1996
- 1996-11-26 GB GBGB9624612.9A patent/GB9624612D0/en active Pending
-
1997
- 1997-11-21 WO PCT/GB1997/003205 patent/WO1998023296A1/en not_active Ceased
- 1997-11-21 DE DE69727311T patent/DE69727311T2/de not_active Expired - Lifetime
- 1997-11-21 AU AU50622/98A patent/AU5062298A/en not_active Abandoned
- 1997-11-21 JP JP52440398A patent/JP4360474B2/ja not_active Expired - Lifetime
- 1997-11-21 AT AT97913322T patent/ATE258069T1/de not_active IP Right Cessation
- 1997-11-21 CN CNB971800111A patent/CN1139404C/zh not_active Expired - Lifetime
- 1997-11-21 EP EP97913322A patent/EP0941129B1/de not_active Expired - Lifetime
- 1997-11-21 CA CA002272296A patent/CA2272296A1/en not_active Abandoned
- 1997-11-21 CZ CZ0232499A patent/CZ297113B6/cs not_active IP Right Cessation
-
1999
- 1999-05-20 NO NO19992406A patent/NO315896B1/no unknown
- 1999-05-26 US US09/318,804 patent/US6232499B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001508766A (ja) | 2001-07-03 |
| CN1238701A (zh) | 1999-12-15 |
| EP0941129B1 (de) | 2004-01-21 |
| NO992406D0 (no) | 1999-05-20 |
| US6232499B1 (en) | 2001-05-15 |
| EP0941129A1 (de) | 1999-09-15 |
| NO315896B1 (no) | 2003-11-10 |
| WO1998023296A1 (en) | 1998-06-04 |
| GB9624612D0 (en) | 1997-01-15 |
| NO992406L (no) | 1999-07-13 |
| AU5062298A (en) | 1998-06-22 |
| CN1139404C (zh) | 2004-02-25 |
| JP4360474B2 (ja) | 2009-11-11 |
| DE69727311T2 (de) | 2004-11-25 |
| CZ232499A3 (cs) | 1999-11-17 |
| CA2272296A1 (en) | 1998-06-04 |
| DE69727311D1 (de) | 2004-02-26 |
| CZ297113B6 (cs) | 2006-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |