ATE258169T1 - Aminothiazol-derivate zur herstellung von beta- laktam antibiotika - Google Patents
Aminothiazol-derivate zur herstellung von beta- laktam antibiotikaInfo
- Publication number
- ATE258169T1 ATE258169T1 AT97952008T AT97952008T ATE258169T1 AT E258169 T1 ATE258169 T1 AT E258169T1 AT 97952008 T AT97952008 T AT 97952008T AT 97952008 T AT97952008 T AT 97952008T AT E258169 T1 ATE258169 T1 AT E258169T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- production
- lactam antibiotics
- aminothiazole derivatives
- derivatives
- Prior art date
Links
- RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical class NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003782 beta lactam antibiotic agent Substances 0.000 title abstract 2
- 239000002132 β-lactam antibiotic Substances 0.000 title abstract 2
- 229940124586 β-lactam antibiotics Drugs 0.000 title abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000007970 thio esters Chemical class 0.000 abstract 1
- 150000003952 β-lactams Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI002439A IT1295935B1 (it) | 1997-10-30 | 1997-10-30 | Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici |
| PCT/EP1997/006654 WO1999023082A1 (en) | 1997-10-30 | 1997-11-28 | AMINOTHIAZOLE DERIVATIVES USEFUL IN THE PREPARATION OF β-LACTAM ANTIBIOTICS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258169T1 true ATE258169T1 (de) | 2004-02-15 |
Family
ID=11378130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97952008T ATE258169T1 (de) | 1997-10-30 | 1997-11-28 | Aminothiazol-derivate zur herstellung von beta- laktam antibiotika |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6255480B1 (de) |
| EP (1) | EP0948491B1 (de) |
| JP (1) | JP2001517248A (de) |
| AT (1) | ATE258169T1 (de) |
| AU (1) | AU5558198A (de) |
| DE (1) | DE69727315T2 (de) |
| DK (1) | DK0948491T3 (de) |
| ES (1) | ES2213229T3 (de) |
| IT (1) | IT1295935B1 (de) |
| PT (1) | PT948491E (de) |
| WO (1) | WO1999023082A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100448856C (zh) * | 2006-06-26 | 2009-01-07 | 山东金城医药化工股份有限公司 | 一种催化合成ae-活性酯的工艺 |
| CN103012312B (zh) * | 2012-12-04 | 2015-05-06 | 山东鑫泉医药有限公司 | 氨噻肟酸生产废水回用的方法 |
| CN103588790A (zh) * | 2013-11-29 | 2014-02-19 | 中国科学院长春应用化学研究所 | 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法 |
| CN103588789A (zh) * | 2013-11-29 | 2014-02-19 | 中国科学院长春应用化学研究所 | 7-氨基-3-氯-3-头孢-4-羧酸的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2758001A1 (de) * | 1977-12-24 | 1979-07-12 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
| US4703046A (en) * | 1978-09-08 | 1987-10-27 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and processes for preparation thereof |
| EP0037380B1 (de) | 1980-03-28 | 1984-09-12 | BIOCHEMIE Gesellschaft m.b.H. | Verfahren zum Herstellen von Cephalosporin-Antibiotika und Zwischenprodukte zur Verwendung in diesem Verfahren und ihre Herstellung |
| EP0055465B1 (de) | 1980-12-31 | 1989-08-23 | Fujisawa Pharmaceutical Co., Ltd. | 7-Acylamino-cephalosporinderivate und Verfahren zu ihrer Herstellung |
| EP0210815A3 (de) * | 1985-07-25 | 1988-04-20 | Beecham Group Plc | 6-Beta-(alpha-veräthertes oxyimino)-acylamino-Penicillansäure-Derivate, ihre Herstellung und Verwendung |
| GB9024223D0 (en) | 1990-11-07 | 1990-12-19 | Fermentech Ltd | Production of hyaluronic acid |
| GB9216759D0 (en) | 1992-08-07 | 1992-09-23 | Finpael Spa | Process for the production of 7-amino thiazolyl cephalosporins |
| AT402928B (de) * | 1994-12-23 | 1997-09-25 | Biochemie Gmbh | Neues verfahren zur herstellung von cefotaxim |
| GB9519883D0 (en) | 1995-09-29 | 1995-11-29 | Fujisawa Pharmaceutical Co | New cephem compounds |
| MY127641A (en) | 1995-10-12 | 2006-12-29 | Essential Therapeutics Inc | Cephalosporin antibiotics |
| IN184690B (de) * | 1996-03-18 | 2000-09-23 | Ranbaxy Lab Ltd |
-
1997
- 1997-10-30 IT IT97MI002439A patent/IT1295935B1/it active IP Right Grant
- 1997-11-28 DE DE1997627315 patent/DE69727315T2/de not_active Expired - Fee Related
- 1997-11-28 AU AU55581/98A patent/AU5558198A/en not_active Abandoned
- 1997-11-28 JP JP52524899A patent/JP2001517248A/ja not_active Ceased
- 1997-11-28 ES ES97952008T patent/ES2213229T3/es not_active Expired - Lifetime
- 1997-11-28 EP EP97952008A patent/EP0948491B1/de not_active Expired - Lifetime
- 1997-11-28 WO PCT/EP1997/006654 patent/WO1999023082A1/en not_active Ceased
- 1997-11-28 PT PT97952008T patent/PT948491E/pt unknown
- 1997-11-28 US US09/331,702 patent/US6255480B1/en not_active Expired - Lifetime
- 1997-11-28 DK DK97952008T patent/DK0948491T3/da active
- 1997-11-28 AT AT97952008T patent/ATE258169T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6255480B1 (en) | 2001-07-03 |
| JP2001517248A (ja) | 2001-10-02 |
| AU5558198A (en) | 1999-05-24 |
| DE69727315D1 (de) | 2004-02-26 |
| EP0948491B1 (de) | 2004-01-21 |
| WO1999023082A1 (en) | 1999-05-14 |
| DE69727315T2 (de) | 2004-11-18 |
| ITMI972439A1 (it) | 1999-04-30 |
| IT1295935B1 (it) | 1999-05-28 |
| DK0948491T3 (da) | 2004-04-13 |
| ES2213229T3 (es) | 2004-08-16 |
| PT948491E (pt) | 2004-06-30 |
| EP0948491A1 (de) | 1999-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8007354L (sv) | Derivat av 6beta-hydroxialkylpenicillansyror med beta-laktamasinhiberande verkan | |
| ATE283264T1 (de) | Zwischenprodukte zur herstellung von metallproteinasehemmern | |
| CY1105836T1 (el) | 12, 13-τροποποιημενα παραγωγα εποθιλονης | |
| ES2191208T3 (es) | Oxiimino-pregnano-carbolactonas. | |
| NO882472D0 (no) | Fremgangsmaate for fremstilling av peptidborsyreinhibitorer for trypsinlignende proteaser. | |
| DE69119216D1 (de) | Enzymatisches Verfahren zur Herstellung von 7-Aminocephalosporinsäure und Derivate | |
| EA199800288A1 (ru) | Производные 5-o-дезозаминил-6-o-метилэритронолида а, способ их получения и их применение для получения биологически активных продуктов | |
| IT1237799B (it) | Processo microbico per la produzione di antibiotici immunosoppressivi | |
| DE69330807D1 (de) | Verfahren zur Herstellung von gereinigtem Enzym | |
| FI953645A7 (fi) | Menetelmä taksaanijohdannaisten valmistamiseksi sekä niiden B-laktaami nivälituotteet | |
| FI925988A0 (fi) | Foerfarande foer framstaellning av b-laktamer | |
| DE68912160D1 (de) | Verfahren zur Herstellung von beta-Lactamderivaten. | |
| MX9305196A (es) | Novedosos 2-sacarinilmetil aril carboxilatos utiles como inhibidores de enzima proteolitica y composiciones y metodos de su uso. | |
| ATE258169T1 (de) | Aminothiazol-derivate zur herstellung von beta- laktam antibiotika | |
| DE68923534D1 (de) | Verfahren zur Herstellung eines organischen Kristalls. | |
| AU532401B2 (en) | Penam-3-alpha-carboxylic acid 1,1-dioxides | |
| EE9800060A (et) | Klavulaanhappe eraldamine fermentatsioonilahusest ultrafiltrimisega | |
| DE69625910D1 (de) | Penamsulfone als beta-laktamase inhibitoren | |
| NO952713L (no) | Fremgangsmåte for fremstilling av substituerte indolonderivater | |
| FI942422A0 (fi) | Menetelmä fysostigmiinin valmistuksessa käytettyjen välituotteiden enantioselektiivistä synteesiä varten | |
| FI942888A0 (fi) | Menetelmä pyranyylisyaaniguanidiinijohdanaisten valmistuksessa käyttökelpoisten välituotteiden valmistamiseksi | |
| FI900665A0 (fi) | Derivat av 3-pyroglutamyl-tiatsolidin -4-karboxylsyra och deras farmakologiska egenskaper. | |
| DE69021001D1 (de) | Enzymatisches Verfahren zur Herstellung von L-Serin. | |
| DE69421653D1 (de) | Neue Anwendung von Alcaligenes faecalis Penicillin G Acylase | |
| ES8506029A1 (es) | Un procedimiento para la preparacion de un compuesto |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0948491 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |