ATE259238T1 - Verfahren zur herstellung eines extraktes des plättchenwachstumsfaktors für zubereitungen zur wundheilung - Google Patents

Verfahren zur herstellung eines extraktes des plättchenwachstumsfaktors für zubereitungen zur wundheilung

Info

Publication number
ATE259238T1
ATE259238T1 AT97908091T AT97908091T ATE259238T1 AT E259238 T1 ATE259238 T1 AT E259238T1 AT 97908091 T AT97908091 T AT 97908091T AT 97908091 T AT97908091 T AT 97908091T AT E259238 T1 ATE259238 T1 AT E259238T1
Authority
AT
Austria
Prior art keywords
platelets
extract
plale
preparing
growth factor
Prior art date
Application number
AT97908091T
Other languages
English (en)
Inventor
Paul Brazeau
Thierry Abribat
Michel Ibea
Michele Boushira
Original Assignee
Theratechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theratechnologies Inc filed Critical Theratechnologies Inc
Application granted granted Critical
Publication of ATE259238T1 publication Critical patent/ATE259238T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97908091T 1996-03-20 1997-03-19 Verfahren zur herstellung eines extraktes des plättchenwachstumsfaktors für zubereitungen zur wundheilung ATE259238T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/618,560 US5834418A (en) 1996-03-20 1996-03-20 Process for the preparation of platelet growth factors extract
PCT/CA1997/000188 WO1997034614A1 (en) 1996-03-20 1997-03-19 Process for the preparation of platelet growth factors extract for wound healing compositions

Publications (1)

Publication Number Publication Date
ATE259238T1 true ATE259238T1 (de) 2004-02-15

Family

ID=24478208

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97908091T ATE259238T1 (de) 1996-03-20 1997-03-19 Verfahren zur herstellung eines extraktes des plättchenwachstumsfaktors für zubereitungen zur wundheilung

Country Status (8)

Country Link
US (1) US5834418A (de)
EP (1) EP1007061B1 (de)
AT (1) ATE259238T1 (de)
AU (1) AU725091B2 (de)
CA (1) CA2249534A1 (de)
DE (1) DE69727595T2 (de)
DK (1) DK1007061T3 (de)
WO (1) WO1997034614A1 (de)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7112320B1 (en) 1995-06-07 2006-09-26 Andre Beaulieu Solid wound healing formulations containing fibronectin
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
US6051008A (en) 1996-12-02 2000-04-18 Angiotrax, Inc. Apparatus having stabilization members for percutaneously performing surgery and methods of use
US6120520A (en) 1997-05-27 2000-09-19 Angiotrax, Inc. Apparatus and methods for stimulating revascularization and/or tissue growth
US6102926A (en) 1996-12-02 2000-08-15 Angiotrax, Inc. Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
US6432119B1 (en) 1999-03-17 2002-08-13 Angiotrax, Inc. Apparatus and methods for performing percutaneous myocardial revascularization and stimulating angiogenesis using autologous materials
US20010041792A1 (en) * 2000-02-03 2001-11-15 Donda Russell S. Extraction of growth factors from tissue
AU2001273421A1 (en) 2000-07-13 2002-01-30 Bioheart, Inc. Deployment system for myocardial cellular material
US8101077B2 (en) * 2001-05-07 2012-01-24 Sivaprasad Sukavaneshvar Device for separating platelets from fluid suspensions
US7011852B2 (en) * 2001-05-07 2006-03-14 Hemogenesis, Llc Separation of platelets from whole blood for use as a healant
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
US7608258B2 (en) * 2002-04-13 2009-10-27 Allan Mishra Method for treatment of tendinosis using platelet rich plasma
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US6905612B2 (en) * 2003-03-21 2005-06-14 Hanuman Llc Plasma concentrate apparatus and method
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
WO2003099412A1 (en) 2002-05-24 2003-12-04 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8308708B2 (en) 2003-07-15 2012-11-13 Abbott Cardiovascular Systems Inc. Deployment system for myocardial cellular material
WO2005065419A2 (en) * 2003-12-29 2005-07-21 Am Biosolutions Method of culturing cells
WO2005065242A2 (en) * 2003-12-29 2005-07-21 Am Biosolutions Method of treating cancer using platelet releasate
WO2005065269A2 (en) * 2003-12-29 2005-07-21 Am Biosolutions Compositions and method for decreasing the appearance of skin wrinkles
US20050191286A1 (en) * 2004-02-09 2005-09-01 Gandy James B. Lyophilized platelet rich plasma for the use in wound healing (chronic or acute) and bone or tissue grafts or repair
DE112004002847T5 (de) * 2004-05-05 2007-04-05 Synthes Gmbh Verwendung von Blutplättchen oder blutblättchenreichem Plasma (PRP)
US7462268B2 (en) 2004-08-20 2008-12-09 Allan Mishra Particle/cell separation device and compositions
ITRM20040638A1 (it) 2004-12-24 2005-03-24 Advance Holdings Ltd Gel piastrinico semisintetico e metodo per la sua preparazione.
ES2426172T3 (es) 2005-02-07 2013-10-21 Hanuman Llc Dispositivo concentrador de plasma
US7694828B2 (en) 2005-04-27 2010-04-13 Biomet Manufacturing Corp. Method and apparatus for producing autologous clotting components
US9074176B2 (en) 2006-01-13 2015-07-07 Two Cells Co., Ltd. Culture medium additive for use in serum-free culturing of animal cell, kit and use thereof
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
JP5479319B2 (ja) 2007-04-12 2014-04-23 バイオメット・バイオロジックス・リミテッド・ライアビリティ・カンパニー ブイ式懸濁液分画システム
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US9095562B2 (en) 2007-07-05 2015-08-04 Regenerative Sciences, Inc. Methods and compositions for optimized expansion and implantation of mesenchymal stem cells
US8282963B2 (en) * 2007-10-15 2012-10-09 The Regents Of The University Of Colorado, A Body Corporate Methods for extracting platelets and compositions obtained therefrom
WO2009085969A2 (en) * 2007-12-19 2009-07-09 Regenerative Sciences, Llc Compositions and methods to promote implantation and engrafment of stem cells
US8835104B2 (en) 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
EP2567692B1 (de) 2008-02-27 2016-04-06 Biomet Biologics, LLC Verwendung einer Vorrichtung zur Erzeugung Interleukin-1-rezeptorantagonistreicher Lösungen
WO2009111338A1 (en) 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
CN102026546A (zh) 2008-03-14 2011-04-20 再生科学有限责任公司 软骨修复的合成物和方法
EP2334785B2 (de) * 2008-09-16 2019-08-14 Mayo Foundation For Medical Education And Research Zusammensetzungen mit thrombozytengehalt
WO2010042658A1 (en) 2008-10-07 2010-04-15 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
EP2337617A4 (de) 2008-10-09 2013-06-12 Bioparadox Llc Plättchenreiche plasmaformulierungen für herzbehandlungen
JP5660572B2 (ja) 2008-11-11 2015-01-28 国立大学法人広島大学 分化誘導培地用添加剤およびその利用
US20110245804A1 (en) 2008-12-05 2011-10-06 Regenerative Sciences, Llc Methods and Compositions to Facilitate Repair of Avascular Tissue
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US20100233282A1 (en) * 2009-03-13 2010-09-16 Allan Mishra Device and methods for delivery of bioactive materials to the right side of the heart
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
EP2264150A1 (de) * 2009-06-09 2010-12-22 Astley E. Smith Dreifachspin-, Doppelpool- und Wiedervoluminisierungsverfahren zum Konzentrieren von Blutplättchen und abgeleitetes Blutplättchenkonzentrat
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US9113950B2 (en) 2009-11-04 2015-08-25 Regenerative Sciences, Llc Therapeutic delivery device
EP2545928B1 (de) 2010-03-10 2016-07-20 Two Cells Co., Ltd Zellpräparat mit mesenchymalen stammzellen und herstellungsverfahren dafür
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
EP3662750A1 (de) 2011-04-07 2020-06-10 Fenwal, Inc. Automatisierte verfahren und systeme zur bereitstellung von thrombozytenkonzentraten mit reduziertem restplasmavolumen und medien zur lagerung solcher thrombozytenkonzentrate
JP6243839B2 (ja) 2011-06-29 2017-12-06 バイオリストーラティブ セラピーズ， インコーポレイテッド 褐色脂肪細胞の組成物および方法
US9682104B2 (en) 2012-01-26 2017-06-20 Jadi Cell Llc Lyophilized platelet lysates
ES2438640B1 (es) * 2012-07-16 2014-11-25 Laboratorios Miramon, S.L. Composición para la regeneración y reparación de la piel
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
EP2948210A4 (de) * 2013-01-28 2016-10-19 Regenerative Sciences Llc Vorrichtung und verfahren zur blutplättchenlyse oder -aktivierung
US10905721B2 (en) 2013-01-28 2021-02-02 Regenexx, Llc. Device and methods for platelet lysis or activation
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
EP2813232B1 (de) * 2013-06-11 2017-08-09 DOT GmbH Verfahren zur Herstellung eines allogenen Wachstumsfaktorextrakts
HK1194912A2 (en) * 2013-09-17 2014-10-24 Bestop Group Holdings Ltd Growth factor concentrate and the use thereof
US9550028B2 (en) 2014-05-06 2017-01-24 Biomet Biologics, LLC. Single step desiccating bead-in-syringe concentrating device
EP3143130B1 (de) 2014-05-16 2024-03-06 Mayo Foundation for Medical Education and Research Zellkulturmedienzusammensetzungen für primärzellen
KR102925966B1 (ko) 2015-05-29 2026-02-10 자디 셀 엘엘씨 미립자 동결건조된 혈소판 용해물 조성물
IL266723B2 (en) * 2016-11-18 2023-10-01 Power Of Platelets Pte Ltd A method for preparing platelet lysate containing growth factors
CN110325226B (zh) * 2016-12-22 2022-03-15 瑞金尼克斯有限责任公司 用于血小板裂解或激活的设备和方法
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー 凍結乾燥方法
RU2710367C2 (ru) * 2018-05-29 2019-12-26 Общество с ограниченной ответственностью "Институт биотехнологий и фармакологии", ООО "ИНБИОФАРМА" Способ получения цитокинов из тромбоцитов пуповинной крови как субстрата для разработки лекарственных средств для человека и животных
CN113597532B (zh) 2019-03-14 2023-02-17 泰尔茂比司特生物技术有限公司 冻干容器填充固定装置、系统及使用方法
IT201900005978A1 (it) * 2019-04-17 2020-10-17 Claudio Migliaresi Composizione topica per il trattamento di ferite, ulcere e piaghe comprendente lisato piastrino preparata al momento dell’uso in condizioni di sterilità e dispositivo per tale preparazione
TWI857807B (zh) * 2020-03-20 2024-10-01 台灣粒線體應用技術股份有限公司 含有粒線體之組合物及其用於作為皮膚纖維母細胞活性促進劑之用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383363A3 (de) * 1984-11-29 1990-10-03 Regents Of The University Of Minnesota Verwendung von Wundheilungsagentien
JPH0653759B2 (ja) * 1986-02-17 1994-07-20 日本ケミカルリサ−チ株式会社 腫瘍細胞増殖抑制および殺腫瘍細胞因子の製造法
AU7988594A (en) * 1993-12-08 1995-06-27 Universite De Montreal Process for the preparation of serum and platelet growth factors extract

Also Published As

Publication number Publication date
AU2019597A (en) 1997-10-10
US5834418A (en) 1998-11-10
DK1007061T3 (da) 2004-06-14
AU725091B2 (en) 2000-10-05
WO1997034614A1 (en) 1997-09-25
DE69727595D1 (de) 2004-03-18
EP1007061B1 (de) 2004-02-11
DE69727595T2 (de) 2004-12-16
EP1007061A1 (de) 2000-06-14
CA2249534A1 (en) 1997-09-25

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