ATE259242T1 - Cd4-derivierte peptide die einen immunrespons inhibieren - Google Patents

Cd4-derivierte peptide die einen immunrespons inhibieren

Info

Publication number
ATE259242T1
ATE259242T1 AT96923591T AT96923591T ATE259242T1 AT E259242 T1 ATE259242 T1 AT E259242T1 AT 96923591 T AT96923591 T AT 96923591T AT 96923591 T AT96923591 T AT 96923591T AT E259242 T1 ATE259242 T1 AT E259242T1
Authority
AT
Austria
Prior art keywords
compounds
residues
domain
human
inhibit
Prior art date
Application number
AT96923591T
Other languages
English (en)
Inventor
Robert Korngold
Ziwei Huang
Original Assignee
Univ Jefferson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Jefferson filed Critical Univ Jefferson
Application granted granted Critical
Publication of ATE259242T1 publication Critical patent/ATE259242T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96923591T 1995-06-29 1996-06-28 Cd4-derivierte peptide die einen immunrespons inhibieren ATE259242T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71095P 1995-06-29 1995-06-29
US403495P 1995-09-20 1995-09-20
PCT/US1996/011176 WO1997001350A1 (en) 1995-06-29 1996-06-28 Cd4-derived peptides that inhibit immune responses

Publications (1)

Publication Number Publication Date
ATE259242T1 true ATE259242T1 (de) 2004-02-15

Family

ID=26668030

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96923591T ATE259242T1 (de) 1995-06-29 1996-06-28 Cd4-derivierte peptide die einen immunrespons inhibieren

Country Status (7)

Country Link
EP (1) EP0835125B1 (de)
JP (1) JPH11510792A (de)
AT (1) ATE259242T1 (de)
AU (1) AU6406496A (de)
CA (1) CA2226017A1 (de)
DE (1) DE69631529T2 (de)
WO (1) WO1997001350A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6277568B1 (en) * 1998-04-09 2001-08-21 Incyte Genomics, Inc. Nucleic acids encoding human ubiquitin-conjugating enzyme homologs
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7439231B2 (en) * 2003-02-14 2008-10-21 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by MHC class II molecules and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109123A (en) * 1988-06-14 1992-04-28 Dana Farber Cancer Institute Alteration of ability of soluble CD4 fragments to bind HIV
US5589458A (en) * 1992-11-13 1996-12-31 Thomas Jefferson University Compounds that inhibit T cell proliferation and methods for using the same
US6100377A (en) * 1994-06-10 2000-08-08 The Trustees Of The University Of Pennsylvania Constrained peptides

Also Published As

Publication number Publication date
AU6406496A (en) 1997-01-30
EP0835125B1 (de) 2004-02-11
EP0835125A4 (de) 2000-03-08
EP0835125A1 (de) 1998-04-15
CA2226017A1 (en) 1997-01-16
WO1997001350A1 (en) 1997-01-16
DE69631529D1 (de) 2004-03-18
DE69631529T2 (de) 2004-12-23
JPH11510792A (ja) 1999-09-21

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties