ATE259641T1 - Amidderivate - Google Patents
AmidderivateInfo
- Publication number
- ATE259641T1 ATE259641T1 AT00946352T AT00946352T ATE259641T1 AT E259641 T1 ATE259641 T1 AT E259641T1 AT 00946352 T AT00946352 T AT 00946352T AT 00946352 T AT00946352 T AT 00946352T AT E259641 T1 ATE259641 T1 AT E259641T1
- Authority
- AT
- Austria
- Prior art keywords
- stands
- stand
- hydrogen
- optionally substituted
- alkyl
- Prior art date
Links
- 150000001408 amides Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 2
- 102000007202 Muscarinic M3 Receptor Human genes 0.000 abstract 1
- 108010008405 Muscarinic M3 Receptor Proteins 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000002249 digestive system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20929299 | 1999-07-23 | ||
| JP33861799 | 1999-11-29 | ||
| PCT/JP2000/004762 WO2001007406A1 (en) | 1999-07-23 | 2000-07-14 | Novel amide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE259641T1 true ATE259641T1 (de) | 2004-03-15 |
Family
ID=26517348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00946352T ATE259641T1 (de) | 1999-07-23 | 2000-07-14 | Amidderivate |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6809108B1 (de) |
| EP (1) | EP1213281B1 (de) |
| AT (1) | ATE259641T1 (de) |
| AU (1) | AU6017800A (de) |
| CA (1) | CA2380074C (de) |
| DE (1) | DE60008396T2 (de) |
| ES (1) | ES2215688T3 (de) |
| WO (1) | WO2001007406A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7074934B2 (en) * | 2000-06-13 | 2006-07-11 | Tularik Limited | Serine protease inhibitors |
| JP2010513277A (ja) * | 2006-12-13 | 2010-04-30 | ギリード・サイエンシズ・インコーポレーテッド | ＣＯＰＤおよび慢性気管支炎の治療のためのムスカリン受容体アンタゴニストおよびβ−アゴニストの共通プロドラッグとしてのモノホスフェート |
| BRPI1014125A2 (pt) | 2009-03-17 | 2016-04-12 | Daiichi Sankyo Co Ltd | composto, composição farmacêutica, e, uso de um composto. |
| US9193762B2 (en) | 2010-12-01 | 2015-11-24 | University Of Mississippi | Selective inhibitors of prolylcarboxypeptidase |
| EP3625232B1 (de) | 2017-05-19 | 2021-06-23 | Council of Scientific and Industrial Research | Substituierte methanopyrido[2,1-a]isoindolone als machr-modulatoren zur behandlung verschiedener assoziierter pathophysiologischer zustände und verfahren zur herstellung davon |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995006635A1 (en) * | 1993-09-02 | 1995-03-09 | Yamanouchi Pharmaceutical Co., Ltd. | Carbamate derivative and medicine containing the same |
| AU685225B2 (en) | 1994-02-10 | 1998-01-15 | Yamanouchi Pharmaceutical Co., Ltd. | Novel carbamate derivative and medicinal composition containing the same |
| US5750540A (en) | 1995-04-28 | 1998-05-12 | Banyu Pharmaceutical Co., Ltd. | 1,4-di-substituted piperidine derivatives |
-
2000
- 2000-07-14 US US10/031,716 patent/US6809108B1/en not_active Expired - Fee Related
- 2000-07-14 DE DE60008396T patent/DE60008396T2/de not_active Expired - Lifetime
- 2000-07-14 AU AU60178/00A patent/AU6017800A/en not_active Abandoned
- 2000-07-14 ES ES00946352T patent/ES2215688T3/es not_active Expired - Lifetime
- 2000-07-14 EP EP00946352A patent/EP1213281B1/de not_active Expired - Lifetime
- 2000-07-14 WO PCT/JP2000/004762 patent/WO2001007406A1/ja not_active Ceased
- 2000-07-14 AT AT00946352T patent/ATE259641T1/de not_active IP Right Cessation
- 2000-07-14 CA CA002380074A patent/CA2380074C/en not_active Expired - Fee Related
-
2004
- 2004-05-05 US US10/838,340 patent/US7452908B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001007406A1 (en) | 2001-02-01 |
| ES2215688T3 (es) | 2004-10-16 |
| AU6017800A (en) | 2001-02-13 |
| CA2380074C (en) | 2009-04-28 |
| EP1213281B1 (de) | 2004-02-18 |
| CA2380074A1 (en) | 2001-02-01 |
| US20040204369A1 (en) | 2004-10-14 |
| DE60008396T2 (de) | 2004-12-16 |
| EP1213281A4 (de) | 2002-10-23 |
| US6809108B1 (en) | 2004-10-26 |
| EP1213281A1 (de) | 2002-06-12 |
| US7452908B2 (en) | 2008-11-18 |
| DE60008396D1 (de) | 2004-03-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69418704D1 (de) | Anthranilsäure derivate | |
| DE69615214D1 (de) | Substituierte heteroaromatische derivate | |
| PT1259489E (pt) | Compostos azapoliciclicos condensados con arilo. | |
| CY1108367T1 (el) | Φαινυλο-καρβοξαμιδικες ενωσεις χρησιμες για την αντιμετωπιση πονου | |
| DK0613900T3 (da) | Triazolopyrimidinderivater med fungiced virkning | |
| PL361361A1 (en) | Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists | |
| CY1111816T1 (el) | Παραγωγο θειαδιαζολινης για την θεραπεια του καρκινου | |
| DE69838662D1 (de) | Morphinanderivate und ihre medizinische Anwendung | |
| EP1184373A4 (de) | Tricyclische verbindungen | |
| HUT68056A (en) | Substituted indoles and azaindoles as angiotensin ii antagonists, pharmaceutical compositions containing same, process for their production and intermediates | |
| ID23954A (id) | Tetrahidrogama-karbolin | |
| EP0604354A3 (de) | Antidepressiv und gegen die Parkinsonsche Krankheit wirkende Verbindungen. | |
| ATE259641T1 (de) | Amidderivate | |
| EP1122253A4 (de) | Quinalozinon-derivate | |
| NO934760D0 (no) | Arylsubstituerte heterosykliske forbindelser | |
| FI935798A0 (fi) | Alkylsubstituerade heterocykliska foereningar | |
| DE69315363D1 (de) | Amphotere tricyclische Verbindungen als antihistaminische und antiallergische Mittel | |
| IL136510A (en) | Acylated hetero-alicyclic derivatives and pharmaceutical compositions containing the same | |
| DE60106168D1 (de) | Substituierte 1-aza-2-imino-heterocyclen und ihre verwendung als aktivatoren der nikotinergen acetylcholinrezeptoren | |
| DK0630893T3 (da) | N,N'-disubstitueret amidderivat | |
| MY133207A (en) | Substituted benzolactam compaunds | |
| EP1000620A4 (de) | Lp(a)MINDERE MITTEL UND INHIBITOREN DER APOPROTEIN (a) PRODUKTION | |
| ATE409698T1 (de) | 1,2,4-triazolderivat, verfahren zu dessen herstellung, und dieses enthaltende pharmazeutische zusammensetzung | |
| AU2002214266A1 (en) | Carbamate derivatives, process for producing the same and use thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |