ATE259800T1 - Substituierte 5-(2,2difluor-1,3-benzodioxol-5-yl) cyclopentenopyridinderivate - Google Patents
Substituierte 5-(2,2difluor-1,3-benzodioxol-5-yl) cyclopentenopyridinderivateInfo
- Publication number
- ATE259800T1 ATE259800T1 AT99900338T AT99900338T ATE259800T1 AT E259800 T1 ATE259800 T1 AT E259800T1 AT 99900338 T AT99900338 T AT 99900338T AT 99900338 T AT99900338 T AT 99900338T AT E259800 T1 ATE259800 T1 AT E259800T1
- Authority
- AT
- Austria
- Prior art keywords
- cyclopentenopyridine
- benzodioxol
- derivatives
- substituted
- group
- Prior art date
Links
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2397998 | 1998-01-21 | ||
| PCT/JP1999/000131 WO1999037639A1 (en) | 1998-01-21 | 1999-01-18 | Substituted 5-(2,2-difluoro-1,3-benzodioxol-5-yl) cyclopentenopyridine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE259800T1 true ATE259800T1 (de) | 2004-03-15 |
Family
ID=12125689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99900338T ATE259800T1 (de) | 1998-01-21 | 1999-01-18 | Substituierte 5-(2,2difluor-1,3-benzodioxol-5-yl) cyclopentenopyridinderivate |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6413979B1 (de) |
| EP (1) | EP1049691B1 (de) |
| JP (1) | JP4432261B2 (de) |
| AT (1) | ATE259800T1 (de) |
| AU (1) | AU742423B2 (de) |
| CA (1) | CA2318184C (de) |
| DE (1) | DE69914880T2 (de) |
| ES (1) | ES2216482T3 (de) |
| WO (1) | WO1999037639A1 (de) |
| ZA (1) | ZA99440B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2511273B8 (de) * | 2011-04-15 | 2019-06-26 | Hivih | Inhibitoren der Virenreplikation, Verfahren zu deren Herstellung und deren therapeutische Verwendung |
| EP2723718A1 (de) | 2011-06-24 | 2014-04-30 | Amgen Inc. | Trpm8-antagonisten und ihre verwendung bei behandlungen |
| JP2014527511A (ja) | 2011-06-24 | 2014-10-16 | アムジエン・インコーポレーテツド | Ｔｒｐｍ８拮抗剤及び治療におけるそれらの使用 |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| EP2821104A1 (de) | 2013-07-05 | 2015-01-07 | Laboratoire Biodim | Inhibitoren der Virenreplikation, Verfahren zu deren Herstellung und deren therapeutische Verwendung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT67665A (en) * | 1991-11-05 | 1995-04-28 | Smithkline Beckman Corp | Indane and indene deriv.s as endothelin receptor antagonists, pharmaceutical compn.s contg. them and process for prepg. them |
| US5389620A (en) | 1993-08-18 | 1995-02-14 | Banyu Pharmaceutical Co., Ltd. | Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives |
| US5714479A (en) | 1993-08-18 | 1998-02-03 | Banyu Pharmaceutical Co., Ltd. | Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives |
| AU675870B2 (en) * | 1993-08-18 | 1997-02-20 | Msd K.K. | Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives |
| EP0906108B1 (de) | 1996-04-04 | 2005-06-15 | Banyu Pharmaceutical Co., Ltd. | Endothelin-antagonisten zur behandlung von herzversagen |
| CA2262676A1 (en) * | 1996-08-09 | 1998-02-19 | Merck & Co., Inc. | Stereoselective deoxygenation reaction |
-
1999
- 1999-01-18 WO PCT/JP1999/000131 patent/WO1999037639A1/en not_active Ceased
- 1999-01-18 EP EP99900338A patent/EP1049691B1/de not_active Expired - Lifetime
- 1999-01-18 CA CA002318184A patent/CA2318184C/en not_active Expired - Fee Related
- 1999-01-18 AU AU18907/99A patent/AU742423B2/en not_active Ceased
- 1999-01-18 AT AT99900338T patent/ATE259800T1/de not_active IP Right Cessation
- 1999-01-18 JP JP2000528561A patent/JP4432261B2/ja not_active Expired - Fee Related
- 1999-01-18 ES ES99900338T patent/ES2216482T3/es not_active Expired - Lifetime
- 1999-01-18 DE DE69914880T patent/DE69914880T2/de not_active Expired - Lifetime
- 1999-01-18 US US09/582,225 patent/US6413979B1/en not_active Expired - Fee Related
- 1999-01-21 ZA ZA9900440A patent/ZA99440B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4432261B2 (ja) | 2010-03-17 |
| ZA99440B (en) | 1999-07-21 |
| CA2318184A1 (en) | 1999-07-29 |
| EP1049691B1 (de) | 2004-02-18 |
| CA2318184C (en) | 2008-11-18 |
| EP1049691A1 (de) | 2000-11-08 |
| US6413979B1 (en) | 2002-07-02 |
| AU742423B2 (en) | 2002-01-03 |
| AU1890799A (en) | 1999-08-09 |
| JP2002501064A (ja) | 2002-01-15 |
| WO1999037639A1 (en) | 1999-07-29 |
| DE69914880T2 (de) | 2004-08-05 |
| ES2216482T3 (es) | 2004-10-16 |
| DE69914880D1 (de) | 2004-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |