ATE260272T1 - Beta-aminsäure-derivate zur verwendung als matrix-metalloproteasen- und tna-alpha-inhibitoren - Google Patents
Beta-aminsäure-derivate zur verwendung als matrix-metalloproteasen- und tna-alpha-inhibitorenInfo
- Publication number
- ATE260272T1 ATE260272T1 AT01924171T AT01924171T ATE260272T1 AT E260272 T1 ATE260272 T1 AT E260272T1 AT 01924171 T AT01924171 T AT 01924171T AT 01924171 T AT01924171 T AT 01924171T AT E260272 T1 ATE260272 T1 AT E260272T1
- Authority
- AT
- Austria
- Prior art keywords
- tna
- beta
- amino acid
- acid derivatives
- matrix metalloproteases
- Prior art date
Links
- 102000005741 Metalloproteases Human genes 0.000 title 1
- 108010006035 Metalloproteases Proteins 0.000 title 1
- 150000001576 beta-amino acids Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000011159 matrix material Substances 0.000 title 1
Classifications
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19018300P | 2000-03-17 | 2000-03-17 | |
| US23546700P | 2000-09-26 | 2000-09-26 | |
| US25206200P | 2000-11-20 | 2000-11-20 | |
| PCT/US2001/008336 WO2001070734A2 (en) | 2000-03-17 | 2001-03-15 | Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE260272T1 true ATE260272T1 (de) | 2004-03-15 |
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ID=27392702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01924171T ATE260272T1 (de) | 2000-03-17 | 2001-03-15 | Beta-aminsäure-derivate zur verwendung als matrix-metalloproteasen- und tna-alpha-inhibitoren |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6495565B2 (de) |
| EP (1) | EP1263756B1 (de) |
| JP (1) | JP2003528097A (de) |
| CN (1) | CN1420881A (de) |
| AR (1) | AR035174A1 (de) |
| AT (1) | ATE260272T1 (de) |
| AU (1) | AU2001250850A1 (de) |
| BR (1) | BR0109469A (de) |
| CA (1) | CA2400168A1 (de) |
| DE (1) | DE60102137T2 (de) |
| ES (1) | ES2215893T3 (de) |
| HK (1) | HK1049334B (de) |
| IL (1) | IL151018A0 (de) |
| NZ (1) | NZ521245A (de) |
| WO (1) | WO2001070734A2 (de) |
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| US7504424B2 (en) * | 2004-07-16 | 2009-03-17 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
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| JP5205971B2 (ja) * | 2006-01-27 | 2013-06-05 | 宇部興産株式会社 | テトラヒドロピラン化合物の製造方法 |
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| US8541572B2 (en) | 2008-11-10 | 2013-09-24 | Merck Sharp & Dohme Corp. | Compounds for the treatment of inflammatory disorders |
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| FR2950056B1 (fr) | 2009-09-17 | 2011-08-26 | Galderma Res & Dev | Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique |
| US8778939B2 (en) | 2009-09-29 | 2014-07-15 | Glaxo Group Limited | Compounds |
| PL2611776T3 (pl) * | 2010-09-03 | 2017-06-30 | Lg Life Sciences Ltd | Sposób wytwarzania pośredniego związku do syntezy leku |
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| WO2014139080A1 (en) * | 2013-03-12 | 2014-09-18 | Boehringer Ingelheim International Trading (Shanghai) Co., Ltd. | Novel process for the manufacture of 3-oxo-tetrahydrofuran |
| EP3057948B1 (de) | 2013-10-14 | 2018-03-14 | Eisai R&D Management Co., Ltd. | Selektiv substituierte chinolinderivate |
| MY192489A (en) | 2013-10-14 | 2022-08-23 | Eisai R&D Man Co Ltd | Selectively substituted quinoline compounds |
| CN103965097A (zh) * | 2014-05-22 | 2014-08-06 | 南开大学 | 一种2-哌啶酮的制备方法 |
| CN104311473B (zh) * | 2014-05-27 | 2016-09-28 | 斯芬克司药物研发(天津)股份有限公司 | 一种哌啶类化合物及其制备方法 |
| WO2016105448A1 (en) * | 2014-12-22 | 2016-06-30 | Darryl Rideout | Imidazoline receptor type 1 ligands for use as therapeutics |
| ES2695533T3 (es) * | 2016-02-01 | 2019-01-08 | Galderma Res & Dev | Compuestos de bencenosulfonamida, método para su síntesis y uso de los mismos en medicina y cosméticos |
| AU2019352741A1 (en) | 2018-10-04 | 2021-05-06 | Assistance Publique-Hôpitaux De Paris (Aphp) | EGFR inhibitors for treating keratodermas |
| CN110498750B (zh) * | 2019-09-02 | 2021-10-15 | 南通大学 | 一种(r)-4-羟基-1-甲氧基丁-2-基氨基甲酸叔丁酯的合成方法 |
| KR102710574B1 (ko) * | 2022-03-28 | 2024-09-27 | 주식회사 비엔에이치리서치 | 약물의 전기생리학적 스크리닝 방법 |
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| JPH02256667A (ja) * | 1988-12-27 | 1990-10-17 | Masatoshi Yamato | 縮合キノリン系化合物およびその製造方法 |
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| ES2183905T3 (es) | 1995-12-20 | 2003-04-01 | Hoffmann La Roche | Inhibidores de metaloproteasa de matriz. |
| EP0818442A3 (de) * | 1996-07-12 | 1998-12-30 | Pfizer Inc. | Cyclische Sulphonderivate als Metalloproteinase-Inhibitoren und zur Hemmung der Produktion von Tumornekrosefaktor |
| AUPP982399A0 (en) | 1999-04-19 | 1999-05-13 | Fujisawa Pharmaceutical Co., Ltd. | Mmp inhibitor |
-
2001
- 2001-03-15 CN CN01806737A patent/CN1420881A/zh active Pending
- 2001-03-15 WO PCT/US2001/008336 patent/WO2001070734A2/en not_active Ceased
- 2001-03-15 AU AU2001250850A patent/AU2001250850A1/en not_active Abandoned
- 2001-03-15 DE DE60102137T patent/DE60102137T2/de not_active Expired - Lifetime
- 2001-03-15 JP JP2001568935A patent/JP2003528097A/ja active Pending
- 2001-03-15 IL IL15101801A patent/IL151018A0/xx unknown
- 2001-03-15 BR BR0109469-6A patent/BR0109469A/pt not_active Application Discontinuation
- 2001-03-15 AT AT01924171T patent/ATE260272T1/de not_active IP Right Cessation
- 2001-03-15 CA CA002400168A patent/CA2400168A1/en not_active Abandoned
- 2001-03-15 ES ES01924171T patent/ES2215893T3/es not_active Expired - Lifetime
- 2001-03-15 NZ NZ521245A patent/NZ521245A/en unknown
- 2001-03-15 HK HK03101437.6A patent/HK1049334B/en not_active IP Right Cessation
- 2001-03-15 EP EP01924171A patent/EP1263756B1/de not_active Expired - Lifetime
- 2001-03-16 US US09/811,116 patent/US6495565B2/en not_active Expired - Lifetime
- 2001-03-16 AR ARP010101253A patent/AR035174A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR035174A1 (es) | 2004-05-05 |
| CA2400168A1 (en) | 2001-09-27 |
| EP1263756A2 (de) | 2002-12-11 |
| EP1263756B1 (de) | 2004-02-25 |
| DE60102137T2 (de) | 2004-10-21 |
| ES2215893T3 (es) | 2004-10-16 |
| WO2001070734A3 (en) | 2002-03-14 |
| US20020013341A1 (en) | 2002-01-31 |
| JP2003528097A (ja) | 2003-09-24 |
| CN1420881A (zh) | 2003-05-28 |
| BR0109469A (pt) | 2003-04-29 |
| NZ521245A (en) | 2004-04-30 |
| DE60102137D1 (de) | 2004-04-01 |
| WO2001070734A2 (en) | 2001-09-27 |
| AU2001250850A1 (en) | 2001-10-03 |
| HK1049334A1 (en) | 2003-05-09 |
| IL151018A0 (en) | 2003-02-12 |
| US6495565B2 (en) | 2002-12-17 |
| HK1049334B (en) | 2004-07-16 |
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