ATE260644T1 - Peptid/lipid-komplexbildung durch co- lyophilisation - Google Patents

Peptid/lipid-komplexbildung durch co- lyophilisation

Info

Publication number
ATE260644T1
ATE260644T1 AT98950743T AT98950743T ATE260644T1 AT E260644 T1 ATE260644 T1 AT E260644T1 AT 98950743 T AT98950743 T AT 98950743T AT 98950743 T AT98950743 T AT 98950743T AT E260644 T1 ATE260644 T1 AT E260644T1
Authority
AT
Austria
Prior art keywords
peptide
lyophilization
complex formation
lipid complex
lipids
Prior art date
Application number
AT98950743T
Other languages
English (en)
Inventor
Jean-Louis Dasseux
Original Assignee
Jean-Louis Dasseux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jean-Louis Dasseux filed Critical Jean-Louis Dasseux
Application granted granted Critical
Publication of ATE260644T1 publication Critical patent/ATE260644T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98950743T 1997-10-02 1998-09-28 Peptid/lipid-komplexbildung durch co- lyophilisation ATE260644T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/942,597 US6287590B1 (en) 1997-10-02 1997-10-02 Peptide/lipid complex formation by co-lyophilization
PCT/US1998/020330 WO1999017740A1 (en) 1997-10-02 1998-09-28 Peptide/lipid complex formation by co-lyophilization

Publications (1)

Publication Number Publication Date
ATE260644T1 true ATE260644T1 (de) 2004-03-15

Family

ID=25478329

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98950743T ATE260644T1 (de) 1997-10-02 1998-09-28 Peptid/lipid-komplexbildung durch co- lyophilisation

Country Status (20)

Country Link
US (4) US6287590B1 (de)
EP (2) EP1358874A1 (de)
JP (1) JP2001522781A (de)
KR (1) KR100588241B1 (de)
CN (1) CN100415210C (de)
AT (1) ATE260644T1 (de)
AU (2) AU749344B2 (de)
CA (1) CA2305704C (de)
DE (1) DE69822176T2 (de)
DK (1) DK1019025T3 (de)
ES (1) ES2217591T3 (de)
HU (1) HUP0003930A3 (de)
IL (1) IL135322A (de)
NO (1) NO329155B1 (de)
NZ (1) NZ503721A (de)
PL (1) PL196579B1 (de)
PT (1) PT1019025E (de)
RU (1) RU2224506C2 (de)
UA (1) UA71551C2 (de)
WO (1) WO1999017740A1 (de)

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US7199102B2 (en) 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
US8568766B2 (en) 2000-08-24 2013-10-29 Gattadahalli M. Anantharamaiah Peptides and peptide mimetics to treat pathologies associated with eye disease
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Also Published As

Publication number Publication date
KR20010030892A (ko) 2001-04-16
CA2305704C (en) 2008-09-30
IL135322A0 (en) 2001-05-20
US6287590B1 (en) 2001-09-11
PT1019025E (pt) 2004-07-30
EP1019025A4 (de) 2001-10-24
HUP0003930A3 (en) 2001-06-28
ES2217591T3 (es) 2004-11-01
US20070167351A1 (en) 2007-07-19
WO1999017740A9 (en) 1999-08-05
HUP0003930A2 (hu) 2001-05-28
DE69822176D1 (de) 2004-04-08
PL196579B1 (pl) 2008-01-31
EP1358874A1 (de) 2003-11-05
US6455088B1 (en) 2002-09-24
PL339654A1 (en) 2001-01-02
WO1999017740A1 (en) 1999-04-15
NO20001683L (no) 2000-05-10
US7189411B2 (en) 2007-03-13
NO20001683D0 (no) 2000-03-31
UA71551C2 (en) 2004-12-15
IL135322A (en) 2005-11-20
JP2001522781A (ja) 2001-11-20
RU2224506C2 (ru) 2004-02-27
AU749344B2 (en) 2002-06-27
AU2002300504B2 (en) 2005-05-12
KR100588241B1 (ko) 2006-06-13
NO329155B1 (no) 2010-08-30
DE69822176T2 (de) 2004-09-16
AU9671598A (en) 1999-04-27
CN1280490A (zh) 2001-01-17
NZ503721A (en) 2001-08-31
EP1019025B1 (de) 2004-03-03
EP1019025A1 (de) 2000-07-19
CN100415210C (zh) 2008-09-03
DK1019025T3 (da) 2004-05-24
CA2305704A1 (en) 1999-04-15
US20030099714A1 (en) 2003-05-29

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