ATE260929T1 - Kosteneffektive methode zur selektiven methylierung von erythromycin a-derivaten - Google Patents

Kosteneffektive methode zur selektiven methylierung von erythromycin a-derivaten

Info

Publication number: ATE260929T1
Authority: AT; Austria
Prior art keywords: erythromycin; cost; derivatives; effective method; selective methylation
Prior art date: 2000-05-15

Application number

AT01936695T

Other languages

English (en)

Inventor

Mohammad Salman

Purna Chandra Ray

Kiran Kumar Gangakhedkar

Dorwal Harish Niranjan Lal

St Railway

Naresh Kumar

Original Assignee

Ranbaxy Lab Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-15

Filing date

2001-05-07

Publication date

2004-03-15

2001-05-07 Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd

2004-03-15 Application granted granted Critical

2004-03-15 Publication of ATE260929T1 publication Critical patent/ATE260929T1/de

Links

ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
238000011935 selective methylation Methods 0.000 title abstract 2
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
239000000010 aprotic solvent Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000012022 methylating agents‎ Substances 0.000 abstract 1
230000001035 methylating effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT01936695T 2000-05-15 2001-05-07 Kosteneffektive methode zur selektiven methylierung von erythromycin a-derivaten ATE260929T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN515DE2000		2000-05-15
PCT/IB2001/000770 WO2001087807A2 (en)	2000-05-15	2001-05-07	A cost effective method for selective methylation of erythromycin a derivatives

Publications (1)

Publication Number	Publication Date
ATE260929T1 true ATE260929T1 (de)	2004-03-15

Family

ID=11097052

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01936695T ATE260929T1 (de)	2000-05-15	2001-05-07	Kosteneffektive methode zur selektiven methylierung von erythromycin a-derivaten

Country Status (15)

Country	Link
US (1)	US6900296B2 (de)
EP (1)	EP1283821B1 (de)
CN (1)	CN1205218C (de)
AT (1)	ATE260929T1 (de)
AU (1)	AU6256301A (de)
BR (1)	BR0110925A (de)
CA (1)	CA2409247A1 (de)
CZ (1)	CZ20023855A3 (de)
DE (1)	DE60102232T2 (de)
DK (1)	DK1283821T3 (de)
ES (1)	ES2217153T3 (de)
MY (1)	MY133929A (de)
PT (1)	PT1283821E (de)
TR (1)	TR200401093T4 (de)
WO (1)	WO2001087807A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2007029265A2 (en) *	2005-04-29	2007-03-15	Kopran Research Laboratories Ltd	A process for preparing clarithromycin and clarithromycin intermediate
ATE396461T1 (de) *	2005-07-13	2008-06-15	Lasersoft Imaging Ag	Bereitstellung einer digitalen kopie eines quellbildes
WO2009023191A2 (en) *	2007-08-09	2009-02-19	Teva Pharmaceutical Industries Ltd.	An improved process for the preparation of clarithromycin
WO2010122571A2 (en) *	2009-04-23	2010-10-28	Elder Pharmaceuticals Ltd.	A process for the selective methylation of erythromycin a derivatives.
CN102942507A (zh) *	2012-11-30	2013-02-27	迈克斯(如东)化工有限公司	一种制备利谷隆的新方法
CN106905204B (zh) *	2017-02-24	2018-07-20	杭州新桂实业有限公司	一种克拉霉素合成过程中甲基化反应溶剂的回收套用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4331803A (en) *	1980-06-04	1982-05-25	Taisho Pharmaceutical Co., Ltd.	Novel erythromycin compounds
JPS60214796A (ja) *	1984-04-06	1985-10-28	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシン類の製法
US4670549A (en) *	1985-03-18	1987-06-02	Taisho Pharmaceutical Co., Ltd.	Method for selective methylation of erythromycin a derivatives

2001
- 2001-05-07 AT AT01936695T patent/ATE260929T1/de not_active IP Right Cessation
- 2001-05-07 US US10/276,505 patent/US6900296B2/en not_active Expired - Fee Related
- 2001-05-07 AU AU62563/01A patent/AU6256301A/en not_active Abandoned
- 2001-05-07 CA CA002409247A patent/CA2409247A1/en not_active Abandoned
- 2001-05-07 DE DE60102232T patent/DE60102232T2/de not_active Expired - Fee Related
- 2001-05-07 PT PT01936695T patent/PT1283821E/pt unknown
- 2001-05-07 EP EP01936695A patent/EP1283821B1/de not_active Expired - Lifetime
- 2001-05-07 WO PCT/IB2001/000770 patent/WO2001087807A2/en not_active Ceased
- 2001-05-07 TR TR2004/01093T patent/TR200401093T4/xx unknown
- 2001-05-07 CN CNB018114628A patent/CN1205218C/zh not_active Expired - Fee Related
- 2001-05-07 DK DK01936695T patent/DK1283821T3/da active
- 2001-05-07 BR BR0110925-1A patent/BR0110925A/pt not_active IP Right Cessation
- 2001-05-07 CZ CZ20023855A patent/CZ20023855A3/cs unknown
- 2001-05-07 ES ES01936695T patent/ES2217153T3/es not_active Expired - Lifetime
- 2001-05-14 MY MYPI20012248 patent/MY133929A/en unknown

Also Published As

Publication number	Publication date
CN1205218C (zh)	2005-06-08
WO2001087807A3 (en)	2002-09-06
DE60102232D1 (de)	2004-04-08
EP1283821A4 (de)	2003-06-11
AU6256301A (en)	2001-11-26
DE60102232T2 (de)	2005-02-24
EP1283821A2 (de)	2003-02-19
WO2001087807A2 (en)	2001-11-22
US20040010128A1 (en)	2004-01-15
TR200401093T4 (tr)	2004-11-22
CZ20023855A3 (cs)	2003-09-17
CN1458934A (zh)	2003-11-26
PT1283821E (pt)	2004-06-30
CA2409247A1 (en)	2001-11-22
EP1283821B1 (de)	2004-03-03
MY133929A (en)	2007-11-30
BR0110925A (pt)	2003-07-22
US6900296B2 (en)	2005-05-31
DK1283821T3 (da)	2004-07-12
ES2217153T3 (es)	2004-11-01

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Legal Events

Date

Code

Title

Description

2004-10-15

UEP

Publication of translation of european patent specification

Ref document number: 1283821

Country of ref document: EP

2006-02-15

REN

Ceased due to non-payment of the annual fee