ATE261422T1 - Verfahren zur herstellung von cephem-verbindungen - Google Patents
Verfahren zur herstellung von cephem-verbindungenInfo
- Publication number
- ATE261422T1 ATE261422T1 AT00956785T AT00956785T ATE261422T1 AT E261422 T1 ATE261422 T1 AT E261422T1 AT 00956785 T AT00956785 T AT 00956785T AT 00956785 T AT00956785 T AT 00956785T AT E261422 T1 ATE261422 T1 AT E261422T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen atom
- compound
- formula
- metal
- alkenyl
- Prior art date
Links
- -1 CEPHEM COMPOUNDS Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002184 metal Substances 0.000 abstract 3
- 229910052751 metal Inorganic materials 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 230000033116 oxidation-reduction process Effects 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 1
- YZCKVEUIGOORGS-IGMARMGPSA-N Protium Chemical compound [1H] YZCKVEUIGOORGS-IGMARMGPSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24727299A JP4510957B2 (ja) | 1999-09-01 | 1999-09-01 | セフェム化合物の製造方法 |
| PCT/JP2000/005851 WO2001016140A1 (en) | 1999-09-01 | 2000-08-30 | Process for the preparation of cephem compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE261422T1 true ATE261422T1 (de) | 2004-03-15 |
Family
ID=17161009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00956785T ATE261422T1 (de) | 1999-09-01 | 2000-08-30 | Verfahren zur herstellung von cephem-verbindungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6576761B1 (de) |
| EP (1) | EP1209160B1 (de) |
| JP (1) | JP4510957B2 (de) |
| KR (1) | KR100458232B1 (de) |
| CN (1) | CN1136221C (de) |
| AT (1) | ATE261422T1 (de) |
| ES (1) | ES2216943T3 (de) |
| HK (1) | HK1048320B (de) |
| WO (1) | WO2001016140A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7401224B2 (en) | 2002-05-15 | 2008-07-15 | Qualcomm Incorporated | System and method for managing sonic token verifiers |
| CA2702257C (en) * | 2007-10-09 | 2016-07-12 | Sopharmia, Inc. | Broad spectrum beta-lactamase inhibitors |
| CN101538273B (zh) * | 2009-04-29 | 2012-05-09 | 四川抗菌素工业研究所有限公司 | 制备(6r,7r)-7-氨基-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-3-h-2-羧酸的方法 |
| US9975905B2 (en) | 2013-03-12 | 2018-05-22 | Gladius Pharmaceuticals Corporation | Derivatized 3-styryl-cephalosporins |
| CN104910185B (zh) * | 2015-03-10 | 2018-02-16 | 国药集团致君(苏州)制药有限公司 | 一种头孢洛林酯中间体母核的制备方法 |
| CN109096303A (zh) * | 2018-09-11 | 2018-12-28 | 南通康鑫药业有限公司 | 一种头孢布烯的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1391437A (en) | 1971-04-07 | 1975-04-23 | Glaxo Lab Ltd | Preparation of antibiotic compounds |
| JPS543087A (en) | 1977-06-03 | 1979-01-11 | Fujisawa Pharmaceut Co Ltd | Preparation of cephalosporin compound |
| JPH01224331A (ja) * | 1988-03-03 | 1989-09-07 | Kanto Denka Kogyo Co Ltd | ビニルハライド及びその誘導体の環元二量化法 |
| US5245027A (en) * | 1989-11-21 | 1993-09-14 | Bristol-Myers Squibb Company | 3-fluorosulfonyloxyceph-3-em compounds |
-
1999
- 1999-09-01 JP JP24727299A patent/JP4510957B2/ja not_active Expired - Fee Related
-
2000
- 2000-08-30 EP EP00956785A patent/EP1209160B1/de not_active Expired - Lifetime
- 2000-08-30 KR KR10-2002-7002717A patent/KR100458232B1/ko not_active Expired - Fee Related
- 2000-08-30 CN CNB008120749A patent/CN1136221C/zh not_active Expired - Fee Related
- 2000-08-30 AT AT00956785T patent/ATE261422T1/de active
- 2000-08-30 WO PCT/JP2000/005851 patent/WO2001016140A1/ja not_active Ceased
- 2000-08-30 HK HK03100580.3A patent/HK1048320B/zh not_active IP Right Cessation
- 2000-08-30 ES ES00956785T patent/ES2216943T3/es not_active Expired - Lifetime
- 2000-08-30 US US10/049,048 patent/US6576761B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HK1048320A1 (en) | 2003-03-28 |
| CN1136221C (zh) | 2004-01-28 |
| CN1371380A (zh) | 2002-09-25 |
| JP4510957B2 (ja) | 2010-07-28 |
| KR100458232B1 (ko) | 2004-11-26 |
| HK1048320B (zh) | 2004-10-21 |
| EP1209160A1 (de) | 2002-05-29 |
| JP2001072686A (ja) | 2001-03-21 |
| KR20020031597A (ko) | 2002-05-02 |
| EP1209160B1 (de) | 2004-03-10 |
| ES2216943T3 (es) | 2004-11-01 |
| US6576761B1 (en) | 2003-06-10 |
| WO2001016140A1 (en) | 2001-03-08 |
| EP1209160A4 (de) | 2002-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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