ATE261449T1 - Thienopyrimidin verbindungen, ihre herstellung und verwendung - Google Patents
Thienopyrimidin verbindungen, ihre herstellung und verwendungInfo
- Publication number
- ATE261449T1 ATE261449T1 AT00911308T AT00911308T ATE261449T1 AT E261449 T1 ATE261449 T1 AT E261449T1 AT 00911308 T AT00911308 T AT 00911308T AT 00911308 T AT00911308 T AT 00911308T AT E261449 T1 ATE261449 T1 AT E261449T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- thienopyrimidine compounds
- thienopyrimidine
- compounds
- Prior art date
Links
- RBNBDIMXFJYDLQ-UHFFFAOYSA-N thieno[3,2-d]pyrimidine Chemical class C1=NC=C2SC=CC2=N1 RBNBDIMXFJYDLQ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7937199 | 1999-03-24 | ||
| JP2000018019 | 2000-01-25 | ||
| PCT/JP2000/001777 WO2000056739A1 (en) | 1999-03-24 | 2000-03-23 | Thienopyrimidine compounds, their production and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE261449T1 true ATE261449T1 (de) | 2004-03-15 |
Family
ID=26420391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00911308T ATE261449T1 (de) | 1999-03-24 | 2000-03-23 | Thienopyrimidin verbindungen, ihre herstellung und verwendung |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6340686B1 (de) |
| EP (1) | EP1163244B1 (de) |
| JP (1) | JP3240293B2 (de) |
| KR (2) | KR100533483B1 (de) |
| CN (1) | CN1349536A (de) |
| AR (1) | AR023152A1 (de) |
| AT (1) | ATE261449T1 (de) |
| AU (1) | AU764019B2 (de) |
| BR (1) | BR0009297A (de) |
| CA (1) | CA2368108C (de) |
| CZ (1) | CZ294747B6 (de) |
| DE (1) | DE60008862T2 (de) |
| DK (1) | DK1163244T3 (de) |
| ES (1) | ES2212992T3 (de) |
| HK (1) | HK1042495B (de) |
| HU (1) | HUP0200550A3 (de) |
| ID (1) | ID30393A (de) |
| IL (1) | IL145549A (de) |
| MX (1) | MXPA01009566A (de) |
| MY (1) | MY124726A (de) |
| NO (1) | NO20014603L (de) |
| NZ (1) | NZ514737A (de) |
| OA (1) | OA11920A (de) |
| PL (1) | PL351202A1 (de) |
| PT (1) | PT1163244E (de) |
| SK (1) | SK13552001A3 (de) |
| TW (1) | TWI225863B (de) |
| WO (1) | WO2000056739A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6828415B2 (en) * | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
| KR20030005205A (ko) * | 2000-02-29 | 2003-01-17 | 다케다 야쿠힌 고교 가부시키가이샤 | 티에노피리미딘 유도체의 제조 방법 |
| US20030134863A1 (en) * | 2000-04-13 | 2003-07-17 | Shuichi Furuya | Preventives/remedies for alzheimer's disease |
| EP1291023A1 (de) * | 2000-06-14 | 2003-03-12 | Takeda Chemical Industries, Ltd. | Formulierungen mit verzögerter wirkstofffreisetzung |
| AU2001288102A1 (en) * | 2000-09-22 | 2002-04-02 | Takeda Chemical Industries Ltd. | Solid preparations |
| WO2002043766A1 (en) * | 2000-11-29 | 2002-06-06 | Takeda Chemical Industries, Ltd. | Medicinal compositions and process for producing the same |
| AU2002221139A1 (en) * | 2000-12-15 | 2002-06-24 | Takeda Chemical Industries Ltd. | Medicinal compositions of nonpeptidyl gonadotropin-releasing hormone agonist or antagonist, process for producing the same and use thereof |
| WO2002078669A1 (fr) * | 2001-03-30 | 2002-10-10 | Takeda Chemical Industries, Ltd. | Solutions medicinales |
| JP2005500352A (ja) | 2001-08-02 | 2005-01-06 | ニューロクライン バイオサイエンシーズ， インコーポレイテッド | ゴナドトロピン放出ホルモンレセプター（ＧｎＲＨ）アンタゴニストとしての１，２，４−トリアジン−３，５−ジオン |
| EP1411941A2 (de) | 2001-08-02 | 2004-04-28 | Neurocrine Biosciences, Inc. | Pyridinon- und pyridazinonderivate als antagonisten des gonadotropin-freisetzungshormon-rezeptors |
| US6939883B2 (en) | 2001-08-02 | 2005-09-06 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| AU2002324586B2 (en) | 2001-08-02 | 2008-04-24 | Neurocrine Biosciences, Inc. | 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists |
| WO2003011870A1 (en) * | 2001-08-02 | 2003-02-13 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists |
| US7569570B2 (en) * | 2002-01-30 | 2009-08-04 | Takeda Pharmaceutical Company Limited | Thienopyrimidines, process for preparing the same and use thereof |
| EP1495768A4 (de) | 2002-04-12 | 2007-12-05 | Takeda Pharmaceutical | Mittel zur prävention/behandlung von hitzewallungen |
| JP2006508050A (ja) * | 2002-08-21 | 2006-03-09 | アストラゼネカ アクチボラグ | ゴナドトロピン放出ホルモンのアンタゴニストとしてのチエノピロール化合物 |
| EP1591446B1 (de) | 2003-01-29 | 2013-03-06 | Takeda Pharmaceutical Company Limited | Thienopyrimidinverbindungen und deren Verwendung |
| GB0307777D0 (en) | 2003-04-04 | 2003-05-07 | Medical Res Council | Conjugate compounds |
| US20060083017A1 (en) * | 2004-10-18 | 2006-04-20 | Bwt Propety, Inc. | Solid-state lighting apparatus for navigational aids |
| KR20080041662A (ko) | 2005-07-22 | 2008-05-13 | 다케다 야쿠힌 고교 가부시키가이샤 | 조기 배란 예방제 |
| EP2329823A4 (de) | 2008-09-03 | 2013-04-03 | Takeda Pharmaceutical | Verfahren zur erhöhung der absorptionsfähigkeit eines präparats sowie präparat mit erhöhter absorptionsfähigkeit |
| MX357841B (es) * | 2012-02-28 | 2018-07-26 | Tiumbio Co Ltd | Antagonistas de los receptores de la hormona liberadora de gonadotropina, método para la preparación de éstos y composición farmacéutica que los contienen. |
| PL2900675T3 (pl) | 2012-09-28 | 2019-08-30 | Takeda Pharmaceutical Company Limited | Sposób wytwarzania pochodnej tienopirymidyny |
| CA2978223A1 (en) * | 2015-02-26 | 2016-09-01 | Takeda Pharmaceutical Company Limited | Formulations of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethyl amino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea |
| EP3518933B2 (de) | 2016-09-30 | 2025-02-26 | Sumitomo Pharma Switzerland GmbH | Verfahren zur behandlung von gebärmuttermyomen und endometriose |
| CN110248661A (zh) | 2016-09-30 | 2019-09-17 | 梦欧文科学有限责任公司 | 前列腺癌的治疗 |
| KR101973074B1 (ko) | 2018-11-30 | 2019-04-26 | 주식회사 티움바이오 | 퓨로피리미딘 화합물의 염 및 결정형, 및 이를 포함하는 약학적 조성물 |
| CN111943960B (zh) * | 2019-07-29 | 2022-02-15 | 广东东阳光药业有限公司 | 取代的嘧啶二酮类化合物及其用途 |
| JP2022551316A (ja) | 2019-10-10 | 2022-12-08 | ミオバント サイエンシズ ゲーエムベーハー | Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素の結晶形 |
| CN111574534B (zh) * | 2020-05-25 | 2021-06-04 | 东莞市东阳光新药研发有限公司 | 苯基取代的噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮类化合物及其用途 |
| BR112022023937A2 (pt) | 2020-05-29 | 2022-12-27 | Myovant Sciences Gmbh | Formas de dosagem oral sólidas de combinação de antagonistas do hormônio liberador de gonadotropina |
| CN111925379B (zh) * | 2020-07-31 | 2022-02-15 | 广东东阳光药业有限公司 | 含氮杂芳基取代的嘧啶二酮类化合物及其用途 |
| CN111909168B (zh) * | 2020-07-31 | 2022-02-01 | 广东东阳光药业有限公司 | 含氮杂环基取代的嘧啶二酮类化合物及其用途 |
| CN112047957B (zh) * | 2020-09-09 | 2022-02-01 | 广东东阳光药业有限公司 | 取代的嘧啶二酮类化合物及其用途 |
| CN113754679B (zh) * | 2020-09-09 | 2023-04-07 | 广东东阳光药业有限公司 | 取代的嘧啶二酮类化合物及其用途 |
| CN113563303B (zh) * | 2020-12-30 | 2022-04-12 | 上海博志研新药物技术有限公司 | 瑞卢戈利中间体及其制备方法 |
| CN115260211B (zh) * | 2021-04-29 | 2024-02-06 | 长春金赛药业有限责任公司 | 含噻吩稠环类衍生物、药物组合物及其制备方法和应用 |
| CN113717149A (zh) * | 2021-09-29 | 2021-11-30 | 成都伊诺达博医药科技有限公司 | 一种瑞卢戈利关键中间体及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW449600B (en) * | 1994-04-19 | 2001-08-11 | Takeda Chemical Industries Ltd | Condensed-ring thiophene derivatives, their production and use |
| UY23948A1 (es) * | 1995-02-08 | 2001-10-25 | Takeda Chemical Industries Ltd | Derivados de anillos condensados de tiofeno su producción y uso. |
| US5627786A (en) * | 1995-02-10 | 1997-05-06 | Micron Quantum Devices, Inc. | Parallel processing redundancy scheme for faster access times and lower die area |
| WO1996028405A1 (fr) * | 1995-03-10 | 1996-09-19 | Nitto Chemical Industry Co., Ltd. | Procede de production de derives de 1,2-ethanediol |
-
2000
- 2000-03-08 TW TW089104127A patent/TWI225863B/zh not_active IP Right Cessation
- 2000-03-21 MY MYPI20001112 patent/MY124726A/en unknown
- 2000-03-23 CA CA002368108A patent/CA2368108C/en not_active Expired - Fee Related
- 2000-03-23 MX MXPA01009566A patent/MXPA01009566A/es active IP Right Grant
- 2000-03-23 JP JP2000087051A patent/JP3240293B2/ja not_active Expired - Fee Related
- 2000-03-23 PL PL00351202A patent/PL351202A1/xx not_active Application Discontinuation
- 2000-03-23 NZ NZ514737A patent/NZ514737A/en unknown
- 2000-03-23 SK SK1355-2001A patent/SK13552001A3/sk unknown
- 2000-03-23 KR KR10-2000-7011511A patent/KR100533483B1/ko not_active Expired - Fee Related
- 2000-03-23 DE DE60008862T patent/DE60008862T2/de not_active Expired - Lifetime
- 2000-03-23 WO PCT/JP2000/001777 patent/WO2000056739A1/en not_active Ceased
- 2000-03-23 KR KR10-2000-7011508A patent/KR100370981B1/ko not_active Expired - Fee Related
- 2000-03-23 OA OA1200100243A patent/OA11920A/en unknown
- 2000-03-23 CZ CZ20013419A patent/CZ294747B6/cs not_active IP Right Cessation
- 2000-03-23 PT PT00911308T patent/PT1163244E/pt unknown
- 2000-03-23 HK HK02104325.6A patent/HK1042495B/en not_active IP Right Cessation
- 2000-03-23 ID IDW00200102298A patent/ID30393A/id unknown
- 2000-03-23 EP EP00911308A patent/EP1163244B1/de not_active Expired - Lifetime
- 2000-03-23 BR BR0009297-5A patent/BR0009297A/pt not_active IP Right Cessation
- 2000-03-23 AU AU33262/00A patent/AU764019B2/en not_active Ceased
- 2000-03-23 IL IL14554900A patent/IL145549A/xx not_active IP Right Cessation
- 2000-03-23 CN CN00807210A patent/CN1349536A/zh active Pending
- 2000-03-23 DK DK00911308T patent/DK1163244T3/da active
- 2000-03-23 AT AT00911308T patent/ATE261449T1/de not_active IP Right Cessation
- 2000-03-23 HU HU0200550A patent/HUP0200550A3/hu unknown
- 2000-03-23 ES ES00911308T patent/ES2212992T3/es not_active Expired - Lifetime
- 2000-03-24 AR ARP000101320A patent/AR023152A1/es not_active Application Discontinuation
- 2000-05-16 US US09/571,215 patent/US6340686B1/en not_active Expired - Lifetime
-
2001
- 2001-09-21 NO NO20014603A patent/NO20014603L/no unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1163244 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |