ATE261492T1 - Methode zur herstellung einer menschlichen neuralen zelllinie - Google Patents

Methode zur herstellung einer menschlichen neuralen zelllinie

Info

Publication number
ATE261492T1
ATE261492T1 AT95936031T AT95936031T ATE261492T1 AT E261492 T1 ATE261492 T1 AT E261492T1 AT 95936031 T AT95936031 T AT 95936031T AT 95936031 T AT95936031 T AT 95936031T AT E261492 T1 ATE261492 T1 AT E261492T1
Authority
AT
Austria
Prior art keywords
producing
cell line
neural cell
human neural
cell
Prior art date
Application number
AT95936031T
Other languages
English (en)
Inventor
Bradley Michael John Stringer
Original Assignee
Cellfactors Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9422523A external-priority patent/GB9422523D0/en
Priority claimed from GBGB9510555.7A external-priority patent/GB9510555D0/en
Application filed by Cellfactors Plc filed Critical Cellfactors Plc
Application granted granted Critical
Publication of ATE261492T1 publication Critical patent/ATE261492T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)
  • Electrotherapy Devices (AREA)
AT95936031T 1994-11-08 1995-11-03 Methode zur herstellung einer menschlichen neuralen zelllinie ATE261492T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9422523A GB9422523D0 (en) 1994-11-08 1994-11-08 Human cell lines
GBGB9510555.7A GB9510555D0 (en) 1995-05-24 1995-05-24 Human cell lines
PCT/GB1995/002591 WO1996014400A1 (en) 1994-11-08 1995-11-03 Human cell-lines

Publications (1)

Publication Number Publication Date
ATE261492T1 true ATE261492T1 (de) 2004-03-15

Family

ID=26305948

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95936031T ATE261492T1 (de) 1994-11-08 1995-11-03 Methode zur herstellung einer menschlichen neuralen zelllinie

Country Status (13)

Country Link
US (2) US6197585B1 (de)
EP (2) EP1441029A1 (de)
JP (2) JPH10509314A (de)
AT (1) ATE261492T1 (de)
AU (1) AU715737B2 (de)
CA (1) CA2203630A1 (de)
CZ (1) CZ138397A3 (de)
DE (1) DE69532679T2 (de)
ES (1) ES2217285T3 (de)
GB (1) GB2294946A (de)
HU (1) HU222040B1 (de)
NZ (1) NZ294906A (de)
WO (1) WO1996014400A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6602708B1 (en) * 1994-11-08 2003-08-05 Cellfactors Plc Neural cultures
US20010049143A1 (en) * 1994-11-08 2001-12-06 Stringer Bradley Michael John Human cell-lines
GB9518606D0 (en) * 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
ATE295875T1 (de) * 1996-03-01 2005-06-15 Isotis Nv Verfahren zur in vitro herstellung von knochen
DE19626830A1 (de) * 1996-07-04 1998-01-08 Max Delbrueck Centrum Konditionales Immortalisationsverfahren für humane Tumorzellen zur Herstellung einer Vakzine
US6713247B1 (en) * 1996-09-03 2004-03-30 Signal Pharmaceuticials, Inc. Human CNS cell lines and methods of use therefor
US6225122B1 (en) * 1998-03-02 2001-05-01 Signal Pharmaceuticals, Inc. Human spinal cord cell lines and methods of use therefor
US6835567B1 (en) 1998-04-14 2004-12-28 Signal Pharmaceuticals, Inc. PNS cell lines and methods of use therefor
PL201401B1 (pl) * 1998-04-17 2009-04-30 Nestle Sa Unieśmiertelniona linia ludzkich keratynocytów, ulepszony sposób unieśmiertelniania komórek skóry ludzkiej, zastosowanie keratynocytów oraz sztuczna skóra
US6913925B1 (en) 1998-08-12 2005-07-05 Signal Pharmaceuticals Llc Human mesencephalon cell lines and methods of use therefor
GB9907243D0 (en) 1999-03-29 1999-05-26 Reneuron Ltd Therapy
AU780073B2 (en) * 1999-05-28 2005-02-24 Cepheid Apparatus and method for cell disruption
JP2004504834A (ja) 2000-08-01 2004-02-19 イスム　リサーチ　ディベロップメント　カンパニー 胚性細胞の定方向分化
US7838292B1 (en) * 2001-03-29 2010-11-23 University Of Louisville Research Foundation, Inc. Methods for obtaining adult human olfactory progenitor cells
WO2003038076A1 (en) * 2001-10-31 2003-05-08 Renomedix Institute Inc. Immortalized mesenchymal cells and utilization thereof
US7534606B2 (en) * 2004-01-12 2009-05-19 National Health Research Institutes Placental stem cell and methods thereof
JP2008507981A (ja) * 2004-07-29 2008-03-21 ステム セル イノベーションズ， インコーポレイテッド 幹細胞の分化
DE602005002430T2 (de) * 2004-09-30 2008-06-19 Reneuron Ltd., Guildford Zelllinie
CN102123745A (zh) 2008-02-29 2011-07-13 科洛普拉斯特公司 用于受试者中活组织的增加和再生的组合物和方法
US20110014267A1 (en) * 2008-02-29 2011-01-20 Hanne Everland Biosynthetic cartilaginous matrix and methods for their production
US8349609B2 (en) * 2009-11-24 2013-01-08 University Of Connecticut Differentiation of human embryonic and induced pluripotent stem cells
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
JP6612227B2 (ja) 2013-11-16 2019-11-27 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ226750A (en) * 1987-10-29 1990-09-26 Amrad Corp Ltd Immortalisation of neural precursor cells by introducing a retrovirus vector containing a myc-oncogene
AU2921289A (en) * 1987-12-09 1989-07-19 Invitron Corporation Human cell life extension
GB9003791D0 (en) * 1990-02-20 1990-04-18 Ludwig Inst Cancer Res Transgenic animals,cell lines therefrom,and their use
US5169764A (en) * 1990-08-08 1992-12-08 Regeneron Pharmaceuticals, Inc. Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras
FR2670215B1 (fr) * 1990-12-10 2000-10-13 Lignees de cellules immortalisees et leurs applications, notamment a la production de cellules differenciees.
WO1994012616A1 (en) * 1992-11-26 1994-06-09 University Of Wales College Of Medicine Human pituitary cell lines
US5766948A (en) * 1993-01-06 1998-06-16 The Regents Of The University Of California Method for production of neuroblasts
US5514552A (en) * 1993-04-30 1996-05-07 Arch Development Corporation Hybrid neuronal cell lines compositions and methods
US5654168A (en) * 1994-07-01 1997-08-05 Basf Aktiengesellschaft Tetracycline-inducible transcriptional activator and tetracycline-regulated transcription units
US5681701A (en) * 1993-07-12 1997-10-28 Mayo Foundation For Medical Education And Research Immortalized human fetal osteoblastic cells
GB9518606D0 (en) 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation

Also Published As

Publication number Publication date
EP0792351B1 (de) 2004-03-10
HU222040B1 (hu) 2003-04-28
DE69532679T2 (de) 2005-03-03
US6340592B1 (en) 2002-01-22
JPH10509314A (ja) 1998-09-14
DE69532679D1 (de) 2004-04-15
EP0792351A1 (de) 1997-09-03
US6197585B1 (en) 2001-03-06
JP2003174868A (ja) 2003-06-24
CA2203630A1 (en) 1996-05-17
AU3811995A (en) 1996-05-31
EP1441029A1 (de) 2004-07-28
AU715737B2 (en) 2000-02-10
HUT77078A (hu) 1998-03-02
GB9522562D0 (en) 1996-01-03
ES2217285T3 (es) 2004-11-01
GB2294946A (en) 1996-05-15
NZ294906A (en) 2000-03-27
WO1996014400A1 (en) 1996-05-17
CZ138397A3 (en) 1997-10-15

Similar Documents

Publication Publication Date Title
DE69532679D1 (de) Methode zur herstellung einer menschlichen neuralen zelllinie
DE3888274D1 (de) Vorrichtung zur intensiven und kontrollierten Herstellung von Mikroorganismen durch Photosynthese.
ATE188952T1 (de) Verrfahren zur herstellung von fällungskieselsäure, aluminium-enthaltende fällungskieselsäuren und deren verwendung zur verstärkung von elastomeren
DE69319502D1 (de) Verfahren und Ofen zur chemischen Herstellung von Aktivkohle
BR9507360A (pt) Métodos para optimizar a relação de variáveis assoicadas com um processo tendo entradas e saidas e para controlar as entradas e saídas de um processo e uma instalação para amônia instalação para amônia e processo para produzir amônia
DE59209922D1 (de) Thrombin sowie Verfahren zu seiner Herstellung
DE69434148D1 (de) Alkoholdehydrogenase, dafür kodierende DNA, Herstellung und Verfahren zur Herstellung von optisch aktiven Alkoholen
DE69802538D1 (de) Verfahren zur herstellung einer hochkonzentrierten kolloidalen kieselsäure-suspension und des dabei hergestellten produktes
DE69605865D1 (de) Poröser ionenaustauscher und methode fur herstellung von entionisiertem wasser
ATE185154T1 (de) Amido-siladiylverbrückte katalysatorkomponente, verfahren zur herstellung und verwendung
DE60042375D1 (de) Verfahren zur Herstellung von 3,3-Dimethylbutanal
DE69224511D1 (de) Verfahren zur Herstellung von Kollagenfasern
DE10196235T1 (de) Verwendung von Kollagen aquatischen Ursprungs zur Herstellung von Trägern für die Gewebebildung sowie diese Träger und Biomaterialien
DE69627400D1 (de) Katalysator zur selektiven Reduktion von Stichoxiden in einer oxidierenden Umgebung, Verfahren zur Herstellung und Verwendung
DE69415474D1 (de) Elektrolytische Zelle zur Herstellung von Hypohalogenit für Wasserbehandlungszwecke
DE3680632D1 (de) Verfahren zur herstellung von kohlenstoffasern und diese kohlenstoffasern.
DE69513186D1 (de) Photokatalysator, methode zur dessen herstellung, und erzeugung von wasserstoff unter verwendung des photokatalysators
ATE149342T1 (de) Verwendung von milchsäurepolymeren zur herstellung von bioresorbierbaren membranen für die gesteuerte gewebsgeneration insbesondere für die parodontologie
DE59910902D1 (de) Verwendung von Chitosanmikropaseln zur Herstellung dekorativer kosmetischer Zubereitungen
DE59405194D1 (de) Copolymerisate ungesättigter carbonsäuren, verfahren zur herstellung und ihre verwendung
DE69314445D1 (de) Verfahren zur Herstellung von Wasserstoffperoxyd
DE68916266D1 (de) Methode zur Herstellung und Stabilisierung von Halosilanen mit Acrylfunktionen.
EP0660422A3 (de) Verfahren und Gerät zur Herstellung von photovoltaischen Zellen.
DE69324692D1 (de) Katalysator und methode zur dessen herstellung
DE59106876D1 (de) Verfahren zur enzymatischen Herstellung optisch aktiver Cyanhydrine.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties