ATE263187T1 - Neuartige heparin bindende peptide - Google Patents

Neuartige heparin bindende peptide

Info

Publication number: ATE263187T1
Authority: AT; Austria
Prior art keywords: heparin; present; binding peptides; exacerbation; injury
Prior art date: 1998-10-06

Application number

AT99119514T

Other languages

English (en)

Inventor

Robert B Harris

Michael Sobel

Original Assignee

Commw Biotechnologies Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-06

Filing date

1999-10-01

Publication date

2004-04-15

1999-10-01 Application filed by Commw Biotechnologies Inc filed Critical Commw Biotechnologies Inc

2004-04-15 Application granted granted Critical

2004-04-15 Publication of ATE263187T1 publication Critical patent/ATE263187T1/de

Links

102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
229920000669 heparin Polymers 0.000 abstract 5
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 4
229960002897 heparin Drugs 0.000 abstract 4
208000027418 Wounds and injury Diseases 0.000 abstract 2
230000002429 anti-coagulating effect Effects 0.000 abstract 2
230000006378 damage Effects 0.000 abstract 2
230000002939 deleterious effect Effects 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
230000005713 exacerbation Effects 0.000 abstract 2
230000000004 hemodynamic effect Effects 0.000 abstract 2
208000014674 injury Diseases 0.000 abstract 2
230000002062 proliferating effect Effects 0.000 abstract 2
230000004865 vascular response Effects 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000002607 heparin antagonist Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

AT99119514T 1998-10-06 1999-10-01 Neuartige heparin bindende peptide ATE263187T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US09/166,930 US6200955B1 (en)	1996-06-11	1998-10-06	Heparin binding peptides

Publications (1)

Publication Number	Publication Date
ATE263187T1 true ATE263187T1 (de)	2004-04-15

Family

ID=22605258

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99119514T ATE263187T1 (de)	1998-10-06	1999-10-01	Neuartige heparin bindende peptide

Country Status (6)

Country	Link
US (2)	US6200955B1 (de)
EP (1)	EP0999219B1 (de)
JP (1)	JP3472513B2 (de)
AT (1)	ATE263187T1 (de)
CA (1)	CA2285151A1 (de)
DE (1)	DE69915977D1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1174506A1 (de) *	2000-06-28	2002-01-23	Stichting Dienst Landbouwkundig Onderzoek	C-terminales Erns-Peptide und Analoge davon
FR2813080B1 (fr)	2000-08-17	2002-11-29	Stago Diagnostica	Peptides anti-heparine
US6664230B1 (en) *	2000-08-24	2003-12-16	The Regents Of The University Of California	Orally administered peptides to ameliorate atherosclerosis
US7723303B2 (en)	2000-08-24	2010-05-25	The Regents Of The University Of California	Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
US7199102B2 (en)	2000-08-24	2007-04-03	The Regents Of The University Of California	Orally administered peptides synergize statin activity
CA2371514C (en) *	2001-02-14	2006-10-31	Commonwealth Biotechnologies, Inc.	Adsorption and removal of endotoxin from physiological fluids using cationic helix peptides
JP2007502112A (ja) *	2003-08-12	2007-02-08	ユニバーシティオブユタリサーチファウンデーション	ヘパリン結合タンパク質：ヘパリン検出のためのセンサー
KR20070089996A (ko)	2004-12-06	2007-09-04	더 리전트 오브 더 유니버시티 오브 캘리포니아	세동맥의 구조 및 기능의 개선 방법
US7637895B2 (en)	2006-08-22	2009-12-29	Nalin David R	System and device for medically treating an individual
CA2663121C (en)	2006-09-08	2016-01-19	Rhode Island Hospital	Treatment, prevention, and reversal of alcohol-induced brain disease
BRPI0816837B1 (pt)	2007-09-28	2022-10-18	Portola Pharmaceuticals, Inc	Composições farmacêuticas, polipeptídeo isolado de duas cadeias e uso de uma composição farmacêutica
PT3604510T (pt)	2009-03-30	2025-06-24	Alexion Pharma Inc	Antídotos para inibidores do fator xa e métodos de utilização dos mesmos
PT2453910T (pt)	2009-07-15	2016-12-07	Portola Pharm Inc	Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento
AR079944A1 (es)	2010-01-20	2012-02-29	Boehringer Ingelheim Int	Anticuerpo neutralizante de la actividad de un anticoagulante
GB201004101D0 (en) *	2010-03-12	2010-04-28	Carmeda Ab	Immobilised biological entities
WO2012130834A1 (en)	2011-03-30	2012-10-04	Boehringer Ingelheim International Gmbh	Anticoagulant antidotes
US8519189B2 (en)	2011-06-01	2013-08-27	University Of British Columbia	Polymers for reversing heparin-based anticoagulation
EP3744840A1 (de)	2014-05-26	2020-12-02	Academisch Ziekenhuis Leiden	Prohämostatische proteine zur behandlung von blutungen
AU2015298263B2 (en)	2014-07-31	2020-05-14	Anji Pharmaceuticals, Inc.	ApoE mimetic peptides and higher potency to clear plasma cholesterol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USH1509H (en) *	1989-06-09	1995-12-05	Eran; Harutyun	Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate
CA2123912C (en) *	1991-11-19	2007-04-17	Roger Aston	Muramyl compounds for treatment of septic shock
US5614494A (en)	1993-11-12	1997-03-25	University Of Michigan, The Board Of Regents Acting For And On Behalf Of	Peptides for heparin and low molecular weight heparin anticoagulation reversal
US5877153A (en)	1996-06-11	1999-03-02	Commonwealth Biotechnologies Inc.	Heparin-binding peptides

1998
- 1998-10-06 US US09/166,930 patent/US6200955B1/en not_active Expired - Lifetime
1999
- 1999-10-01 AT AT99119514T patent/ATE263187T1/de not_active IP Right Cessation
- 1999-10-01 EP EP99119514A patent/EP0999219B1/de not_active Expired - Lifetime
- 1999-10-01 DE DE69915977T patent/DE69915977D1/de not_active Expired - Lifetime
- 1999-10-05 CA CA002285151A patent/CA2285151A1/en not_active Abandoned
- 1999-10-06 JP JP28518599A patent/JP3472513B2/ja not_active Expired - Fee Related
2001
- 2001-02-14 US US09/905,691 patent/US6756206B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2000136202A (ja)	2000-05-16
CA2285151A1 (en)	2000-04-06
JP3472513B2 (ja)	2003-12-02
EP0999219A2 (de)	2000-05-10
EP0999219B1 (de)	2004-03-31
US20020164329A1 (en)	2002-11-07
EP0999219A3 (de)	2000-05-24
US6200955B1 (en)	2001-03-13
US6756206B2 (en)	2004-06-29
DE69915977D1 (de)	2004-05-06

Legal Events

Date	Code	Title	Description
2004-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE263187T1 (de)	2004-04-15	Neuartige heparin bindende peptide
DK0696326T5 (da)	2003-07-14	Anvendelse af NDV til fremstilling af et medikament til behandling af cancer
FI956019L (fi)	1996-01-25	Eristettyjä peptidejä, jotka muodostavat komplekseja MHC-molekyyli HLA-C-klooni-10:n kanssa, ja niiden käyttö
TR200001218T2 (tr)	2001-05-21	İkameli karboksamidotiazoller, bunların üretimi ve bunları içeren farmasötik bileşimler.
DK0960127T3 (da)	2010-03-29	Isoleret dimert fibroblastaktiverende protein-alfa og anvendelser deraf
PT960107E (pt)	2003-02-28	Compostos de paclitaxel 6-tio-substituidos
CY1108610T1 (el)	2014-04-09	Πεπτιδια της il-2 και παραγωγα αυτων και χρηση αυτων ως θεραπευτικοι παραγοντες
PL323490A1 (en)	1998-03-30	Tetralinic compounds exibiting acitity against multgiple-drug refractoriness
CO4910133A1 (es)	2000-04-24	Antagonistas de 5-h[1f]
AU2001235006A1 (en)	2001-08-20	Prophylactic and therapeutic monoclonal antibodies
BR9913533A (pt)	2001-06-05	Processos para tratar hipertensão e composições para uso nos mesmos
SE9904377D0 (sv)	1999-12-01	Pharmaceutical combinations
DE69614149D1 (de)	2001-08-30	Chinolinderivate als antimalariamittel
DE69943042D1 (de)	2011-01-27	Herstellungsverfahren von dispergiermittel enthaltenden konzentrate mit hohem molekulargewicht
NO20002408D0 (no)	2000-05-09	5-HT1F antagonister
EA200400670A1 (ru)	2004-10-28	Фармацевтические композиции, содержащие 3,4-пропинопергидропурины, и их применение для блокирования нейронной передачи
IT8919735A0 (it)	1989-03-10	Procedimento per la riduzione del cod da reflui industriali o urbani.
DE69005136D1 (de)	1994-01-27	Grundierungszusammensetzung.
IL143279A0 (en)	2002-04-21	Novel therapeutic application of low molecular weight heparin
FI930269A7 (fi)	1993-03-22	Koostumus, joka aikaansaa bioaktiivisten aineiden parannetun poistuman verivirrasta
FR2705244B1 (fr)	1995-07-07	Culotte de sauvetage.
BR9710992A (pt)	2000-10-24	Derivados anticovulsivos úteis no tratamento de psorìase
RU97100921A (ru)	1999-02-10	Антигипоксический комплекс
DE59009464D1 (de)	1995-09-07	Vernetzte Triazinpolymerisate und ihre Verwendung als Vernetzungsmittel.
FR2717390B1 (fr)	1996-05-31	Compositions thérapeutiques à base de peptides capables d'inhiber la libération de pepsine.