ATE264340T1 - Stabilisierung von gefriergetrocknetem kuchen - Google Patents
Stabilisierung von gefriergetrocknetem kuchenInfo
- Publication number
- ATE264340T1 ATE264340T1 AT00952959T AT00952959T ATE264340T1 AT E264340 T1 ATE264340 T1 AT E264340T1 AT 00952959 T AT00952959 T AT 00952959T AT 00952959 T AT00952959 T AT 00952959T AT E264340 T1 ATE264340 T1 AT E264340T1
- Authority
- AT
- Austria
- Prior art keywords
- freeze
- stabilization
- dried cake
- sugar
- cake
- Prior art date
Links
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
- YMAWOPBAYDPSLA-UHFFFAOYSA-N glycylglycine Chemical compound [NH3+]CC(=O)NCC([O-])=O YMAWOPBAYDPSLA-UHFFFAOYSA-N 0.000 abstract 2
- 108010008488 Glycylglycine Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000004067 bulking agent Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 229940043257 glycylglycine Drugs 0.000 abstract 1
- 150000005846 sugar alcohols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Preparation Of Fruits And Vegetables (AREA)
- Freezing, Cooling And Drying Of Foods (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199901130 | 1999-08-17 | ||
| PCT/DK2000/000454 WO2001012653A1 (en) | 1999-08-17 | 2000-08-16 | Stabilisation of freeze-dried cake |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE264340T1 true ATE264340T1 (de) | 2004-04-15 |
Family
ID=8101362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00952959T ATE264340T1 (de) | 1999-08-17 | 2000-08-16 | Stabilisierung von gefriergetrocknetem kuchen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1210361B1 (de) |
| JP (1) | JP2003507388A (de) |
| AT (1) | ATE264340T1 (de) |
| AU (1) | AU6558400A (de) |
| DE (1) | DE60009926T2 (de) |
| WO (1) | WO2001012653A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2325653T3 (es) | 2001-12-21 | 2009-09-11 | Novo Nordisk Health Care Ag | Composicion liquida de polipeptidos del factor vii. |
| GB0207092D0 (en) * | 2002-03-26 | 2002-05-08 | Sod Conseils Rech Applic | Stable pharmaceutical composition containing factor VIII |
| SG187991A1 (en) * | 2002-05-02 | 2013-03-28 | Wyeth Corp | Calicheamicin derivative-carrier conjugates |
| WO2003092731A1 (en) * | 2002-05-03 | 2003-11-13 | Novo Nordisk A/S | Stabilised solid compositions of modified factor vii |
| DK1517698T4 (da) † | 2002-06-21 | 2018-01-29 | Novo Nordisk Healthcare Ag | Stabiliserede faste sammensætninger af Faktor VIIa-polypeptider |
| BRPI0408417A (pt) * | 2003-03-18 | 2006-03-21 | Novo Nordisk Healthcare Ag | métodos para a produção de um resìduo de gla purificado contendo serina protease, para a purificação de um resìduo de gla contendo serina protease e para estabilização de um resìduo de gla contendo serina protease, e, composição |
| US7897734B2 (en) | 2003-03-26 | 2011-03-01 | Novo Nordisk Healthcare Ag | Method for the production of proteins |
| WO2004112828A1 (en) | 2003-06-25 | 2004-12-29 | Novo Nordisk Health Care Ag | Liquid composition of factor vii polypeptides |
| KR20140093711A (ko) * | 2003-12-19 | 2014-07-28 | 노보 노르디스크 헬스 케어 악티엔게젤샤프트 | 인자 ｖｉｉ 폴리펩티드의 안정화된 조성물 |
| AU2011203354B2 (en) * | 2003-12-19 | 2014-07-17 | Novo Nordisk Health Care Ag | Stabilised compositions of factor VII polypeptides |
| PT2337580E (pt) * | 2008-09-03 | 2012-05-28 | Octapharma Ag | Composições estabilizadas para o factor viii produzido de forma recombinante |
| FR2947181B1 (fr) | 2009-06-26 | 2012-05-04 | Lfb Biotechnologies | Composition de facteur vii |
| JP2014522827A (ja) * | 2011-06-28 | 2014-09-08 | ロイコケア・アクチェンゲゼルシャフト | （ポリ）ペプチドのアンフォールディングを防止し、および／または（ポリ）ペプチドの（リ）フォールディングを誘導するための方法 |
| EP3370695A1 (de) * | 2015-11-05 | 2018-09-12 | Novo Nordisk A/S | Fviii-formulierung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT308050B (de) * | 1970-08-28 | 1973-06-25 | Boehringer Mannheim Gmbh | Reagens zur Bestimmung der γ-Glutamyltranspeptidase |
| US4777043A (en) * | 1985-12-17 | 1988-10-11 | Genentech, Inc. | Stabilized human tissue plasminogen activator compositions |
| JPH0650999B2 (ja) * | 1988-09-12 | 1994-07-06 | 日本商事株式会社 | 血液凝固因子安定化法 |
| US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
-
2000
- 2000-08-16 AT AT00952959T patent/ATE264340T1/de not_active IP Right Cessation
- 2000-08-16 EP EP00952959A patent/EP1210361B1/de not_active Expired - Lifetime
- 2000-08-16 WO PCT/DK2000/000454 patent/WO2001012653A1/en not_active Ceased
- 2000-08-16 DE DE60009926T patent/DE60009926T2/de not_active Expired - Lifetime
- 2000-08-16 AU AU65584/00A patent/AU6558400A/en not_active Abandoned
- 2000-08-16 JP JP2001517551A patent/JP2003507388A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE60009926T2 (de) | 2005-04-07 |
| JP2003507388A (ja) | 2003-02-25 |
| AU6558400A (en) | 2001-03-13 |
| WO2001012653A1 (en) | 2001-02-22 |
| EP1210361B1 (de) | 2004-04-14 |
| DE60009926D1 (de) | 2004-05-19 |
| EP1210361A1 (de) | 2002-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |