ATE265456T1 - 2-amino-6-anilino-purine und deren verwendung als arzneimittel - Google Patents

2-amino-6-anilino-purine und deren verwendung als arzneimittel

Info

Publication number
ATE265456T1
ATE265456T1 AT00916840T AT00916840T ATE265456T1 AT E265456 T1 ATE265456 T1 AT E265456T1 AT 00916840 T AT00916840 T AT 00916840T AT 00916840 T AT00916840 T AT 00916840T AT E265456 T1 ATE265456 T1 AT E265456T1
Authority
AT
Austria
Prior art keywords
anilino
amino
purines
medicinal products
diseases
Prior art date
Application number
AT00916840T
Other languages
English (en)
Inventor
Patricia Imbach
Hans-Georg Capraro
Juerg Zimmermann
Giorgio Caravatti
Pascal Furet
Wolfgang Karl-Diether Brill
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE265456T1 publication Critical patent/ATE265456T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00916840T 1999-02-18 2000-02-16 2-amino-6-anilino-purine und deren verwendung als arzneimittel ATE265456T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9903762.4A GB9903762D0 (en) 1999-02-18 1999-02-18 Organic compounds
PCT/EP2000/001271 WO2000049018A1 (en) 1999-02-18 2000-02-16 2-amino-6-anilino-purines and their use as medicaments

Publications (1)

Publication Number Publication Date
ATE265456T1 true ATE265456T1 (de) 2004-05-15

Family

ID=10848053

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00916840T ATE265456T1 (de) 1999-02-18 2000-02-16 2-amino-6-anilino-purine und deren verwendung als arzneimittel

Country Status (13)

Country Link
US (1) US6767906B2 (de)
EP (1) EP1153024B1 (de)
JP (1) JP2002537300A (de)
CN (1) CN1183133C (de)
AT (1) ATE265456T1 (de)
AU (1) AU3804500A (de)
BR (1) BR0008365A (de)
CA (1) CA2360353A1 (de)
DE (1) DE60010234T2 (de)
ES (1) ES2219326T3 (de)
GB (1) GB9903762D0 (de)
PT (1) PT1153024E (de)
WO (1) WO2000049018A1 (de)

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GB0004890D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004887D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004888D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
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FR2818642B1 (fr) 2000-12-26 2005-07-15 Hoechst Marion Roussel Inc Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion
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TW200528101A (en) 2004-02-03 2005-09-01 Astrazeneca Ab Chemical compounds
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JP5590040B2 (ja) 2008-11-12 2014-09-17 アリアド・ファーマシューティカルズ・インコーポレイテッド キナーゼ阻害剤としてのピラジノピラジンおよび誘導体
US9180127B2 (en) 2009-12-29 2015-11-10 Dana-Farber Cancer Institute, Inc. Type II Raf kinase inhibitors
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CN116492347A (zh) * 2013-09-18 2023-07-28 华安医学股份有限公司 一种活化ampk的化合物及其用途
US9840517B2 (en) * 2013-09-18 2017-12-12 Beijing Hanmi Pharmaceutical Co., Ltd. Compound inhibiting activities of BTK and/or JAK3 kinases
US10047070B2 (en) 2013-10-18 2018-08-14 Dana-Farber Cancer Institute, Inc. Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7)
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EP3236959B1 (de) 2014-12-23 2025-09-24 Dana-Farber Cancer Institute, Inc. Hemmer der cyclinabhängigen kinase 7 (cdk7)
AU2016243529B2 (en) * 2015-03-27 2021-03-25 Dana-Farber Cancer Institute, Inc. Inhibitors of cyclin-dependent kinases
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CN114149432B (zh) * 2016-09-30 2024-07-05 斯坦福国际研究院 用于癌症治疗的双重clk/cdk1抑制剂
KR20190135464A (ko) * 2016-12-01 2019-12-06 압토스 바이오사이언시스 인코포레이티드 Brd4 및 jak2 이중 억제제로서의 융합된 피리미딘 및 이의 사용 방법
JP7590185B2 (ja) 2018-06-25 2024-11-26 ダナ－ファーバー キャンサー インスティテュート， インコーポレイテッド Ｔａｉｒｅファミリーキナーゼインヒビターおよびそれらの使用
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Also Published As

Publication number Publication date
PT1153024E (pt) 2004-08-31
CN1340054A (zh) 2002-03-13
WO2000049018A1 (en) 2000-08-24
DE60010234D1 (de) 2004-06-03
CA2360353A1 (en) 2000-08-24
JP2002537300A (ja) 2002-11-05
CN1183133C (zh) 2005-01-05
GB9903762D0 (en) 1999-04-14
HK1042479A1 (en) 2002-08-16
EP1153024A1 (de) 2001-11-14
BR0008365A (pt) 2001-11-13
DE60010234T2 (de) 2005-04-14
US6767906B2 (en) 2004-07-27
AU3804500A (en) 2000-09-04
EP1153024B1 (de) 2004-04-28
US20020016329A1 (en) 2002-02-07
ES2219326T3 (es) 2004-12-01

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