ATE266401T1 - Nefiracetam zur prophylaxe und behandlung von propofol verursachtem gedächtnisschwund - Google Patents

Nefiracetam zur prophylaxe und behandlung von propofol verursachtem gedächtnisschwund

Info

Publication number: ATE266401T1
Authority: AT; Austria
Prior art keywords: propofol; nefiracetam; prophylaxis; treatment; memory
Prior art date: 1997-07-15

Application number

AT98931103T

Other languages

English (en)

Inventor

Ciaran Regan

David O'gorman

Alan O'connell

Tadashi Shiotani

Original Assignee

Daiichi Seiyaku Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-15

Filing date

1998-07-14

Publication date

2004-05-15

1998-07-14 Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE266401T1 publication Critical patent/ATE266401T1/de

Links

NGHTXZCKLWZPGK-UHFFFAOYSA-N nefiracetam Chemical compound CC1=CC=CC(C)=C1NC(=O)CN1C(=O)CCC1 NGHTXZCKLWZPGK-UHFFFAOYSA-N 0.000 title abstract 2
OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 title abstract 2
229960004134 propofol Drugs 0.000 title abstract 2
238000011282 treatment Methods 0.000 title abstract 2
229950004663 nefiracetam Drugs 0.000 title 1
238000011321 prophylaxis Methods 0.000 title 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000004076 pyridyl group Chemical group 0.000 abstract 2
-1 2-oxo-1-pyrrolidinyl group Chemical group 0.000 abstract 1
208000000044 Amnesia Diseases 0.000 abstract 1
208000031091 Amnestic disease Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
230000006986 amnesia Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000003193 general anesthetic agent Substances 0.000 abstract 1
238000001990 intravenous administration Methods 0.000 abstract 1
230000003449 preventive effect Effects 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Anesthesiology (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

AT98931103T 1997-07-15 1998-07-14 Nefiracetam zur prophylaxe und behandlung von propofol verursachtem gedächtnisschwund ATE266401T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP18949597		1997-07-15
PCT/JP1998/003162 WO1999003466A1 (fr)	1997-07-15	1998-07-14	Substance prophylactique ou therapeutique contre l'amnesie

Publications (1)

Publication Number	Publication Date
ATE266401T1 true ATE266401T1 (de)	2004-05-15

Family

ID=16242234

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98931103T ATE266401T1 (de)	1997-07-15	1998-07-14	Nefiracetam zur prophylaxe und behandlung von propofol verursachtem gedächtnisschwund

Country Status (8)

Country	Link
US (1)	US6281242B1 (de)
EP (1)	EP1020189B1 (de)
KR (1)	KR20010021897A (de)
CN (1)	CN1264301A (de)
AT (1)	ATE266401T1 (de)
AU (1)	AU8131198A (de)
DE (1)	DE69823851D1 (de)
WO (1)	WO1999003466A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1221249C (zh)	1998-08-19	2005-10-05	斯凯伊药品加拿大公司	普鲁泊福的可注射水分散体
US20040077709A1 (en) *	1999-05-31	2004-04-22	Daiichi Pharmaceutical Co., Ltd.	Neuronal death inhibitors
US6423739B1 (en)	2000-02-23	2002-07-23	Daiichi Pharmaceutical Co., Ltd.	Method for aiding cerebral recovery following neurodegeneration
KR100823668B1 (ko) *	2000-12-28	2008-04-21	해밀턴 파마슈티컬스 인코포레이티드	신경성 통증 치료 및 예방약
ATE404192T1 (de) *	2001-08-22	2008-08-15	Hamilton Pharmaceuticals Inc	Verwendung von nefiracetam zur behandlung von postischemischer neurodegeneration
ES2369903T3 (es) *	2003-01-23	2011-12-09	University Of Florida Research Foundation, Incorporated	Método y aparato para la vertificación de la concentración intravenosa (iv) de fármacos usando aliento exhalado.
US20080146583A1 (en) *	2003-05-15	2008-06-19	Pfizer Inc	Treatment of Incontinence
US20060241144A1 (en) *	2005-04-20	2006-10-26	Albert Cha	Method for treating apathy syndrome
US8184643B2 (en) *	2005-09-14	2012-05-22	Ciena Corporation	Device, system, and method for transporting data using combined broadband and legacy network infrastructures
WO2012031125A2 (en)	2010-09-01	2012-03-08	The General Hospital Corporation	Reversal of general anesthesia by administration of methylphenidate, amphetamine, modafinil, amantadine, and/or caffeine
US10314503B2 (en)	2013-06-27	2019-06-11	The General Hospital Corporation	Systems and methods for tracking non-stationary spectral structure and dynamics in physiological data
WO2014210527A1 (en)	2013-06-28	2014-12-31	The General Hospital Corporation	System and method to infer brain state during burst suppression
EP4166072A1 (de)	2013-09-13	2023-04-19	The General Hospital Corporation	Systeme und verfahren zur verbesserten gehirnüberwachung während der allgemeinen anästhesie und sedierung
WO2018102402A1 (en)	2016-11-29	2018-06-07	The General Hospital Corporation	Systems and methods for analyzing electrophysiological data from patients undergoing medical treatments
EP3897594B1 (de)	2018-12-19	2024-07-10	The General Hospital Corporation	Dextroamphetamin und lisdexamfetamin zur umkehrung der dexmedetomidinsedation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1141287B (it)	1979-06-13	1986-10-01	Nattermann A & Cie	Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
DE2923975A1 (de) *	1979-06-13	1980-12-18	Nattermann A & Cie	Pyrrolidinone, verfahren zu deren herstellung und diese enthaltende arzneimittel
SK279285B6 (sk)	1991-05-02	1998-09-09	Daiichi Pharmaceutical Co.	Použitie n-(2,6-dimetylfenyl)-2-(2-oxo-1-pyrolidin
JP3388778B2 (ja) *	1991-05-02	2003-03-24	第一製薬株式会社	脳血管性痴呆改善剤
ZA923134B (en) *	1991-05-02	1993-01-27	Daiichi Seiyaku Co	Agent for improving dementia
US5461157A (en)	1992-06-19	1995-10-24	Daiichi Pharmaceutical Co., Ltd.	Process for preparing pyrrolidinylacetamide derivatives
US6107330A (en) *	1995-08-07	2000-08-22	Daiichi Pharmaceutical Co., Ltd.	Inhibitor for narcotic analgesic dependence/resistance acquisition
US5996023A (en) *	1996-10-31	1999-11-30	Sensormatic Electronics Corporation	Efficient pre-alarm buffer management in intelligent video information management system

1998
- 1998-07-14 AU AU81311/98A patent/AU8131198A/en not_active Abandoned
- 1998-07-14 EP EP98931103A patent/EP1020189B1/de not_active Expired - Lifetime
- 1998-07-14 WO PCT/JP1998/003162 patent/WO1999003466A1/ja not_active Ceased
- 1998-07-14 KR KR1020007000461A patent/KR20010021897A/ko not_active Ceased
- 1998-07-14 US US09/462,099 patent/US6281242B1/en not_active Expired - Fee Related
- 1998-07-14 DE DE69823851T patent/DE69823851D1/de not_active Expired - Lifetime
- 1998-07-14 AT AT98931103T patent/ATE266401T1/de not_active IP Right Cessation
- 1998-07-14 CN CN98807225A patent/CN1264301A/zh active Pending

Also Published As

Publication number	Publication date
EP1020189A4 (de)	2002-07-31
EP1020189A1 (de)	2000-07-19
DE69823851D1 (de)	2004-06-17
EP1020189B1 (de)	2004-05-12
KR20010021897A (ko)	2001-03-15
AU8131198A (en)	1999-02-10
CN1264301A (zh)	2000-08-23
US6281242B1 (en)	2001-08-28
WO1999003466A1 (fr)	1999-01-28

Legal Events

Date	Code	Title	Description
2004-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69823851D1 (de)	2004-06-17	Nefiracetam zur prophylaxe und behandlung von propofol verursachtem gedächtnisschwund
ATE232862T1 (de)	2003-03-15	Oxazolidinon derivate und diese enthaltende pharmazeutische zusammensetzungen
NO934719D0 (no)	1993-12-20	Hemmere av HIV-protease som er nyttige for behandling av AIDS
MX19368A (es)	1993-09-01	Procedimiento para la preparacion de derivados heterociclicos que contienen nitrogeno benzofusionado y compuesto obtenido.
DE68914438D1 (de)	1994-05-11	N-(3,4-dimethoxycinnamoyl)-Anthranilsäure enthaltende Arzneimittelzusammensetzungen.
DE69735090D1 (de)	2006-04-06	Neurotrophin antagoniste zur behandlung von der epilepsie, alzheimer'schen krankheit und schmerzen
NO975666D0 (no)	1997-12-05	Pyrroldovater og medisinsk sammensetning
EA200000614A1 (ru)	2001-02-26	2,3-замещенные соединения индола в качестве ингибиторов сох-2
NO934718D0 (no)	1993-12-20	Nye HIV protease inhibitorer
DE69315836D1 (de)	1998-01-29	Pyrazolpyridine für die behandlung der anämie
DE69518159D1 (de)	2000-08-31	Mittel zur vorsorge und heilung von typ i allergischen krankheiten
ES2191763T3 (es)	2003-09-16	Inhibidor del desarrollo de dependencia/tolerancia a un agente analgesico narcotico.
HUT77204A (hu)	1998-03-02	Karbamoil-karbonsavamidok, eljárás előállításukra, hatóanyagként ezeket a vegyületeket tartalmazó fungicid készítmények, és alkalmazásuk
DE69522118D1 (de)	2001-09-13	Thiazolidonon- oder oxazolidinonderivate zur behandlung von angina pectoris und zusammensetzungen die diese als wirkstoffe enthält
FI923662A0 (fi)	1992-08-14	Terapeutiska medel.
EP0505389A4 (en)	1992-12-02	Antiparasitic composition for animal use
ATE141259T1 (de)	1996-08-15	N-substituierte carbonyloxyalkylpyrrol enthaltende insekticide, acarizide und molluskizide mittel
DE69327077D1 (de)	1999-12-30	Carbamoylpyrrolidon-Derivate zur Behandlung von Depressionen und cerebrovasculären Störungen
EP0653207A4 (de)	1995-03-06	Aids-virus-infektion hemmende zusammensetzung.
PT819676E (pt)	2003-01-31	Cristais anidros
DE69220371D1 (de)	1997-07-17	Hemmstoff der blutgefässhypertrophie