ATE266407T1 - Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe - Google Patents

Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe

Info

Publication number: ATE266407T1
Authority: AT; Austria
Prior art keywords: composition containing; delayed release; medicinal composition; composition; mixtures
Prior art date: 2000-10-30

Application number

AT01956758T

Other languages

English (en)

Inventor

Himadri Sen

Rajesh S Kshirsagar

Anupa Menjoge

Original Assignee

Lupin Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-30

Filing date

2001-08-03

Publication date

2004-05-15

2001-08-03 Application filed by Lupin Ltd filed Critical Lupin Ltd

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE266407T1 publication Critical patent/ATE266407T1/de

Links

239000000203 mixture Substances 0.000 title abstract 5
KEJCWVGMRLCZQQ-YJBYXUATSA-N Cefuroxime axetil Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(=O)OC(C)OC(C)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 KEJCWVGMRLCZQQ-YJBYXUATSA-N 0.000 title abstract 3
230000003111 delayed effect Effects 0.000 title 1
229920001577 copolymer Polymers 0.000 abstract 4
229960002620 cefuroxime axetil Drugs 0.000 abstract 2
239000011248 coating agent Substances 0.000 abstract 2
238000000576 coating method Methods 0.000 abstract 2
238000013270 controlled release Methods 0.000 abstract 2
239000006185 dispersion Substances 0.000 abstract 2
125000000524 functional group Chemical group 0.000 abstract 2
NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract 1
CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
239000008199 coating composition Substances 0.000 abstract 1
239000011162 core material Substances 0.000 abstract 1
239000004014 plasticizer Substances 0.000 abstract 1
DBABZHXKTCFAPX-UHFFFAOYSA-N probenecid Chemical compound CCCN(CCC)S(=O)(=O)C1=CC=C(C(O)=O)C=C1 DBABZHXKTCFAPX-UHFFFAOYSA-N 0.000 abstract 1
229960003081 probenecid Drugs 0.000 abstract 1
125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
238000013268 sustained release Methods 0.000 abstract 1
239000012730 sustained-release form Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)

AT01956758T 2000-10-30 2001-08-03 Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe ATE266407T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US70204200A	2000-10-30	2000-10-30
PCT/IN2001/000141 WO2002036126A1 (en)	2000-10-30	2001-08-03	Rapidly disintegrating sustained release cefuroxime axetil composition

Publications (1)

Publication Number	Publication Date
ATE266407T1 true ATE266407T1 (de)	2004-05-15

Family

ID=24819640

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01956758T ATE266407T1 (de)	2000-10-30	2001-08-03	Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe

Country Status (7)

Country	Link
US (1)	US6932981B2 (de)
EP (1)	EP1330250B1 (de)
AT (1)	ATE266407T1 (de)
AU (1)	AU2001278673A1 (de)
DE (1)	DE60103299T2 (de)
ES (1)	ES2220789T3 (de)
WO (1)	WO2002036126A1 (de)

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US6544555B2 (en)	2000-02-24	2003-04-08	Advancis Pharmaceutical Corp.	Antibiotic product, use and formulation thereof
US7527807B2 (en) *	2000-06-21	2009-05-05	Cubist Pharmaceuticals, Inc.	Compositions and methods for increasing the oral absorption of antimicrobials
US20020068078A1 (en)	2000-10-13	2002-06-06	Rudnic Edward M.	Antifungal product, use and formulation thereof
PL363679A1 (en) *	2001-05-09	2004-11-29	Bayer Healthcare Ag	Novel use of 2-phenyl-substituted imidazotriazinones
EP1434571B1 (de) *	2001-10-05	2005-05-11	SurModics, Inc.	Beschichtungen mit immobilisierten partikeln sowie verwendungen derselben
DE10232113A1 (de) *	2002-07-16	2004-01-29	Bayer Ag	Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
SE0203778D0 (sv) *	2002-12-09	2002-12-09	Astrazeneca Ab	A new oral immediated release dosage form
GB0400971D0 (en) *	2004-01-16	2004-02-18	Sandoz Ag	Pharmaceutical compositions
ATE446086T1 (de) *	2004-03-19	2009-11-15	Zentiva Kimyasal Ueruenler San	Herstellung von lipid-beschichtetem cefuroxime axetil
DE102004023069A1 (de) *	2004-05-11	2005-12-08	Bayer Healthcare Ag	Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
US7294347B2 (en) *	2004-06-21	2007-11-13	Council Of Scientific And Industrial Research	Coating compositions for bitterness inhibition
US7378109B2 (en) *	2004-12-23	2008-05-27	Council Of Scientific And Industrial Research	Pharmaceutical composition for improving palatability of drugs and process for preparation thereof
US8481565B2 (en)	2004-12-27	2013-07-09	Eisai R&D Management Co., Ltd.	Method for stabilizing anti-dementia drug
US20060246003A1 (en) *	2004-12-27	2006-11-02	Eisai Co. Ltd.	Composition containing anti-dementia drug
US20070129402A1 (en) *	2004-12-27	2007-06-07	Eisai Research Institute	Sustained release formulations
DE102005001989A1 (de) *	2005-01-15	2006-07-20	Bayer Healthcare Ag	Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009240A1 (de) *	2005-03-01	2006-09-07	Bayer Healthcare Ag	Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
DE102005009241A1 (de) *	2005-03-01	2006-09-07	Bayer Healthcare Ag	Arzneiformen mit kontrollierter Bioverfügbarkeit
JP2008535922A (ja) *	2005-04-12	2008-09-04	エラン・ファルマ・インターナショナル・リミテッド	細菌感染を治療するためのセファロスポリンを含む放出制御組成物
DE102005019458A1 (de) *	2005-04-25	2006-10-26	Grünenthal GmbH	Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
CA2606386C (en) *	2005-04-29	2014-06-10	Cubist Pharmaceuticals, Inc.	Therapeutic compositions
CA2623657A1 (en) *	2005-09-29	2007-04-12	Bayer Healthcare Ag	Pde inhibitors and combinations thereof for the treatment of urological disorders
US8497258B2 (en)	2005-11-12	2013-07-30	The Regents Of The University Of California	Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
WO2007063552A1 (en) *	2005-12-02	2007-06-07	Lupin Limited	Stable taste masked formulations of cephalosporins
EP2167057A1 (de) *	2007-06-13	2010-03-31	Bayer HealthCare AG	Pde-hemmer zur behandlung von gehörschäden
IL187159A0 (en)	2007-07-03	2009-02-11	Gur Megiddo	Use of metadoxine in relief of alcohol intoxication
DK3045043T3 (da)	2009-02-26	2020-08-03	Relmada Therapeutics Inc	Orale farmaceutiske sammensætninger af 3-hydroxy-n-methylmorphinan med forlænget frigivelse og fremgangsmåde til anvendelse
WO2010144865A2 (en)	2009-06-12	2010-12-16	Meritage Pharma, Inc.	Methods for treating gastrointestinal disorders
CN104856975A (zh) *	2015-05-26	2015-08-26	青岛海之星生物科技有限公司	一种丙磺舒缓释胶囊及制备方法
CN104940207A (zh) *	2015-05-26	2015-09-30	青岛海之星生物科技有限公司	一种头孢氨苄丙磺舒复方缓释胶囊及制备方法
CN104825483B (zh) *	2015-05-26	2017-10-13	青岛海之星生物科技有限公司	一种丙磺舒缓释片及制备方法
US11554112B2 (en)	2018-06-07	2023-01-17	Herum Therapeutics International Limited	Combinations of β-lactam compounds and probenecid and uses thereof
EA202192193A1 (ru)	2019-02-13	2021-11-09	Итерум Терапьютикс Интернэшнл Лимитед	Комбинации бета-лактамных соединений и пробенецида и их применения
CN111704562A (zh) *	2020-08-07	2020-09-25	安徽康正康仁药业有限公司	一种盘装丙磺舒钠无菌原料药冻干工艺
EP4505999A1 (de) *	2023-08-07	2025-02-12	Panntherapi	Probenecid-formulierungen

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US4325960A (en) *	1979-02-13	1982-04-20	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab)	6-Amidinopenicillanic acid derivatives including the radical of a β-lactamase inhibitor
IL85538A (en) *	1987-02-27	1991-09-16	Lilly Co Eli	Sustained release matrix tablet formulations containing hydrophilic and enteric polymers
US5580578A (en) *	1992-01-27	1996-12-03	Euro-Celtique, S.A.	Controlled release formulations coated with aqueous dispersions of acrylic polymers
ATE217789T1 (de) *	1992-06-04	2002-06-15	Smithkline Beecham Corp	Angenehm schmeckende pharmazeutische zusammensetzungen
FR2772615B1 (fr) *	1997-12-23	2002-06-14	Lipha	Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
AU3277899A (en) *	1998-03-03	1999-09-20	Dae Woong Chemical Co., Ltd.	Pharmaceutical composition containing cefuroxime axetil stable for moisture absorption
DE19835823A1 (de) *	1998-08-10	1999-10-07	Lindopharm Gmbh	Pharmazeutische Zusammensetzung, Verfahren zu ihrer Herstellung und ihre Verwendung sowie aus ihr hergestellte wässerige Suspension
PT1194124E (pt) *	1999-06-11	2004-02-27	Ranbaxy Lab Ltd	Composicoes de sabor mascarado

2001
- 2001-08-03 AT AT01956758T patent/ATE266407T1/de not_active IP Right Cessation
- 2001-08-03 ES ES01956758T patent/ES2220789T3/es not_active Expired - Lifetime
- 2001-08-03 EP EP01956758A patent/EP1330250B1/de not_active Expired - Lifetime
- 2001-08-03 DE DE60103299T patent/DE60103299T2/de not_active Expired - Fee Related
- 2001-08-03 WO PCT/IN2001/000141 patent/WO2002036126A1/en not_active Ceased
- 2001-08-03 AU AU2001278673A patent/AU2001278673A1/en not_active Abandoned
- 2001-08-13 US US09/928,466 patent/US6932981B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2002036126A1 (en)	2002-05-10
EP1330250A1 (de)	2003-07-30
DE60103299D1 (de)	2004-06-17
EP1330250B1 (de)	2004-05-12
AU2001278673A1 (en)	2002-05-15
ES2220789T3 (es)	2004-12-16
US20020119195A1 (en)	2002-08-29
US6932981B2 (en)	2005-08-23
DE60103299T2 (de)	2005-05-12

Legal Events

Date	Code	Title	Description
2004-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60103299D1 (de)	2004-06-17	Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe
DK1276470T3 (da)	2007-06-18	Smagskaskerende overtrækssammensætning
BG105061A (bg)	2001-07-31	Ентерично покрит фармацевтичен състав и метод за получаване
BR0207932A (pt)	2004-03-02	Composições farmacêuticas de sabor mascarado
DE60128901D1 (de)	2007-07-26	Beschichtungszusammensetzung zur geschmacksmaskierung
AU2001266635A1 (en)	2001-12-11	Copolymers of ethylene and selected acrylate esters
NO20014025D0 (no)	2001-08-17	Behandling av dentinsensitivitet med vandige dispersjoner av hydrofobe ko-hydrofile kopolymerer
YU36700A (sh)	2003-01-31	Oralni farmaceutski oblik za doziranje sa produženim oslobađanjem
AU2003266351A1 (en)	2004-05-25	Multilayer dosage forms, which contain active substances and which comprise a neutral core, and an inner and outer coating consisting of methacrylate copolymers and methacrylate monomers
HUP9900337A2 (hu)	1999-06-28	Omega-3-Politelítetlen savak orális adagolási formái gyulladásos bélbetegségek kezelésére
CA2473991A1 (en)	2003-08-07	Controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor
AU6868994A (en)	1995-02-09	Controlled release formulations coated with aqueous dispersions of acrylic polymers
AU2508001A (en)	2001-06-12	Aqueous dispersions of acrylate modified alkyd resins and use thereof
BR9913104A (pt)	2001-05-08	Formas de medicamentos revestidos com desprendimento controlado de substãncia ativa
WO2005046649A3 (de)	2005-10-27	Mehrschichtige arzneiform, enthaltend eine in bezug auf die wirkstoffreigabe modularisch wirkende substanz
DK0977557T3 (da)	2003-09-15	Pelletpræparat til behandling af tarmkanalen
ATE380022T1 (de)	2007-12-15	Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen
AU4488893A (en)	1994-03-03	Enteric coated soft capsules and method of preparation thereof
DK0704208T3 (da)	2004-07-12	Overtræks- og bindemiddel for lægemiddelformer samt dermed fremstillet lægemiddelform
CO5690538A2 (es)	2006-10-31	Formulaciones de multiples particulas de pantoprazol
ES2185911T3 (es)	2003-05-01	Composiciones farmaceuticas que contienen polimeros de ortoester tamponados.
MXPA04003540A (es)	2004-07-22	Utilizacion de un copolimero para producir una forma galenica que contiene un peptido o proteina como agente activo.
AU6142600A (en)	2001-03-05	Controlled release from copolymers of acrylic or methacrylic acid/l-dopa, acrylic or methacrylic acid/l-alpha-methyl dopa, acrylic or methacrylic acid/carbidopaand their combinations
KR940005264A (ko)	1994-03-21	국소치료제
NO942936L (no)	1996-02-09	Formuleringer med regulert frigivelse belagt med vandige dispersjoner av acrylpolymerer