ATE268186T1 - Biotinverbindungen zum zielen auf tumore und infektionsherde - Google Patents
Biotinverbindungen zum zielen auf tumore und infektionsherdeInfo
- Publication number
- ATE268186T1 ATE268186T1 AT95922233T AT95922233T ATE268186T1 AT E268186 T1 ATE268186 T1 AT E268186T1 AT 95922233 T AT95922233 T AT 95922233T AT 95922233 T AT95922233 T AT 95922233T AT E268186 T1 ATE268186 T1 AT E268186T1
- Authority
- AT
- Austria
- Prior art keywords
- tumors
- infection
- targe
- signs
- biotin compounds
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical class N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title 1
- XFLVBMBRLSCJAI-ZKWXMUAHSA-N biotin amide Chemical class N1C(=O)N[C@@H]2[C@H](CCCCC(=O)N)SC[C@@H]21 XFLVBMBRLSCJAI-ZKWXMUAHSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012216 imaging agent Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
- A61K47/557—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells the modifying agent being biotin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0495—Pretargeting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25426094A | 1994-06-06 | 1994-06-06 | |
| US26551694A | 1994-06-24 | 1994-06-24 | |
| PCT/US1995/007184 WO1995033491A1 (en) | 1994-06-06 | 1995-06-05 | Biotin compounds for targetting tumors and sites of infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268186T1 true ATE268186T1 (de) | 2004-06-15 |
Family
ID=26943939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95922233T ATE268186T1 (de) | 1994-06-06 | 1995-06-05 | Biotinverbindungen zum zielen auf tumore und infektionsherde |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0769966B1 (de) |
| JP (2) | JP4013996B2 (de) |
| AT (1) | ATE268186T1 (de) |
| AU (1) | AU700864B2 (de) |
| CA (1) | CA2192384A1 (de) |
| DE (1) | DE69533105T2 (de) |
| WO (1) | WO1995033491A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030269A1 (it) * | 2003-02-14 | 2004-08-15 | Advance Holdings Ltd | Sale di cetilpiridino di un agente antiinfiammatorio |
| CN110183504B (zh) * | 2019-06-13 | 2023-07-07 | 湖南大学 | 一种具有肿瘤靶向性的吉西他滨前体药物及其制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5108921A (en) * | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| US5258126A (en) * | 1989-09-12 | 1993-11-02 | Pall Corporation | Method for obtaining platelets |
| DE4011601A1 (de) * | 1990-04-10 | 1991-10-17 | Boehringer Mannheim Gmbh | Hapten-biotin-konjugate und ihre verwendung |
| US5326778A (en) * | 1992-03-03 | 1994-07-05 | Research Corporation Technologies, Inc. | Conjugates of biotin and deferoxamine for radioimmunoimaging and radioimmunotherapy |
| US5578287A (en) * | 1992-06-09 | 1996-11-26 | Neorx Corporation | Three-step pretargeting methods using improved biotin-active agent |
| EP0646019B9 (de) * | 1992-06-09 | 2002-12-18 | Neorx Corporation | Biotin-DOTA Konjugate und deren Verwendung in "Pretargeting" Verfahren |
-
1995
- 1995-06-05 AT AT95922233T patent/ATE268186T1/de not_active IP Right Cessation
- 1995-06-05 DE DE69533105T patent/DE69533105T2/de not_active Expired - Fee Related
- 1995-06-05 AU AU26991/95A patent/AU700864B2/en not_active Ceased
- 1995-06-05 WO PCT/US1995/007184 patent/WO1995033491A1/en not_active Ceased
- 1995-06-05 JP JP50128396A patent/JP4013996B2/ja not_active Expired - Fee Related
- 1995-06-05 CA CA002192384A patent/CA2192384A1/en not_active Abandoned
- 1995-06-05 EP EP95922233A patent/EP0769966B1/de not_active Expired - Lifetime
-
2007
- 2007-07-13 JP JP2007183924A patent/JP2007302686A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10508003A (ja) | 1998-08-04 |
| JP4013996B2 (ja) | 2007-11-28 |
| AU700864B2 (en) | 1999-01-14 |
| WO1995033491A1 (en) | 1995-12-14 |
| DE69533105D1 (de) | 2004-07-08 |
| CA2192384A1 (en) | 1995-12-14 |
| DE69533105T2 (de) | 2005-06-09 |
| AU2699195A (en) | 1996-01-04 |
| JP2007302686A (ja) | 2007-11-22 |
| EP0769966A1 (de) | 1997-05-02 |
| EP0769966B1 (de) | 2004-06-02 |
| HK1014670A1 (en) | 1999-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |