ATE268338T1 - Antibiotische cryptdin-peptide und verfahren zur ihrer verwendung - Google Patents

Antibiotische cryptdin-peptide und verfahren zur ihrer verwendung

Info

Publication number
ATE268338T1
ATE268338T1 AT95937487T AT95937487T ATE268338T1 AT E268338 T1 ATE268338 T1 AT E268338T1 AT 95937487 T AT95937487 T AT 95937487T AT 95937487 T AT95937487 T AT 95937487T AT E268338 T1 ATE268338 T1 AT E268338T1
Authority
AT
Austria
Prior art keywords
amino acids
cryptdin
seq
provides
amino acid
Prior art date
Application number
AT95937487T
Other languages
English (en)
Inventor
Michael E Selsted
Andre J Ouellette
Original Assignee
Univ California
Shriners Hospitals For Cripple
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Shriners Hospitals For Cripple filed Critical Univ California
Application granted granted Critical
Publication of ATE268338T1 publication Critical patent/ATE268338T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4721—Cationic antimicrobial peptides, e.g. defensins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Rehabilitation Therapy (AREA)
AT95937487T 1994-11-18 1995-10-05 Antibiotische cryptdin-peptide und verfahren zur ihrer verwendung ATE268338T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/342,268 US5844072A (en) 1992-05-26 1994-11-18 Antibiotic cryptdin peptides and methods of their use
PCT/US1995/013328 WO1996016075A1 (en) 1994-11-18 1995-10-05 Antibiotic cryptdin peptides and methods of their use

Publications (1)

Publication Number Publication Date
ATE268338T1 true ATE268338T1 (de) 2004-06-15

Family

ID=23341089

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95937487T ATE268338T1 (de) 1994-11-18 1995-10-05 Antibiotische cryptdin-peptide und verfahren zur ihrer verwendung

Country Status (11)

Country Link
US (4) US5844072A (de)
EP (1) EP0792279B1 (de)
JP (1) JPH10509047A (de)
KR (1) KR970707145A (de)
AT (1) ATE268338T1 (de)
AU (1) AU697378B2 (de)
DE (1) DE69533108D1 (de)
IL (1) IL115682A0 (de)
MX (1) MX9703628A (de)
WO (1) WO1996016075A1 (de)
ZA (1) ZA958887B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304715A (en) * 1979-06-08 1981-12-08 Derek Hudson Enkephalin analogues
US5844072A (en) 1992-05-26 1998-12-01 University Of California Antibiotic cryptdin peptides and methods of their use
AU752704B2 (en) * 1997-10-24 2002-09-26 Invitrogen Corporation Recombinational cloning using nucleic acids having recombination sites
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
EP1434783A4 (de) * 2001-03-16 2006-06-07 Lilly Co Eli Lp-säugerproteine; verwandte reagenzien
US7119070B2 (en) * 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
US20040219516A1 (en) * 2002-07-18 2004-11-04 Invitrogen Corporation Viral vectors containing recombination sites
US7605194B2 (en) * 2003-06-24 2009-10-20 Ppg Industries Ohio, Inc. Aqueous dispersions of polymer-enclosed particles, related coating compositions and coated substrates
ATE469984T1 (de) * 2003-12-01 2010-06-15 Life Technologies Corp Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon
US20100184911A1 (en) * 2009-01-22 2010-07-22 Ppg Industries Ohio, Inc. Aqueous dispersions of polymer-enclosed particles, related coating compositions and coated substrates
US20080255052A1 (en) * 2004-12-23 2008-10-16 The Regents Of The University Of California Immunologic regulation by theta defensins

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5844072A (en) 1992-05-26 1998-12-01 University Of California Antibiotic cryptdin peptides and methods of their use
US4304715A (en) * 1979-06-08 1981-12-08 Derek Hudson Enkephalin analogues
US4543252A (en) * 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4659692A (en) * 1982-11-19 1987-04-21 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4705777A (en) * 1985-02-25 1987-11-10 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
EP0394318A1 (de) * 1987-12-09 1990-10-31 Medical Research Council Polymere und polymer-peptid-konjugate
US5032574A (en) * 1988-05-26 1991-07-16 Invitron Corporation Novel antimicrobial peptide
US5229500A (en) * 1989-08-30 1993-07-20 Regeneron Pharmaceuticals, Inc. Brain derived neurotrophic factor
US5237051A (en) * 1990-12-06 1993-08-17 Vanderbilt University Purified enterotoxin receptor protein
US5436155A (en) * 1991-12-31 1995-07-25 Arch Development Corporation Isolated DNA encoding a somatostatin receptor
JPH07507213A (ja) * 1992-05-22 1995-08-10 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 消化器デフェンシン，そのｃＤＮＡ配列及び製造方法並びにその使用
US5422424A (en) 1992-05-26 1995-06-06 The Regents Of The University Of California Antibiotic cryptdin peptides and methods of their use
CA2136103C (en) * 1992-05-26 2004-03-30 The General Hospital Corporation Antibiotic cryptdin peptides and methods of their use
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
JP3654667B2 (ja) 1994-07-22 2005-06-02 生化学工業株式会社 ポリペプチド、その製造法およびそれをコードするｄｎａ
US5589364A (en) * 1994-07-29 1996-12-31 Magainin Pharmaceuticals Inc. Recombinant production of biologically active peptides and proteins

Also Published As

Publication number Publication date
US6300470B1 (en) 2001-10-09
DE69533108D1 (de) 2004-07-08
EP0792279A4 (de) 1998-04-15
US5840498A (en) 1998-11-24
IL115682A0 (en) 1996-01-19
MX9703628A (es) 1998-07-31
AU3958795A (en) 1996-06-17
EP0792279B1 (de) 2004-06-02
EP0792279A1 (de) 1997-09-03
US5844072A (en) 1998-12-01
JPH10509047A (ja) 1998-09-08
US5731149A (en) 1998-03-24
AU697378B2 (en) 1998-10-01
KR970707145A (ko) 1997-12-01
ZA958887B (en) 1996-05-09
WO1996016075A1 (en) 1996-05-30

Similar Documents

Publication Publication Date Title
Greenberg et al. Human beta-casein. Amino acid sequence and identification of phosphorylation sites.
Gregory et al. The primary structure of human urogastrone
Raj et al. Salivary statherin. Dependence on sequence, charge, hydrogen bonding potency, and helical conformation for adsorption to hydroxyapatite and inhibition of mineralization.
DE69431995D1 (de) Stabile Produkte des bakterientötenden/durchlässigkeiterhöhenden Proteins (PBI) und diese enthaltende Arzneimittelzusammensetzungen
DE69533108D1 (de) Antibiotische cryptdin-peptide und verfahren zur ihrer verwendung
McGavin et al. Fibronectin binding determinants of the Staphylococcus aureus fibronectin receptor
ES8802161A1 (es) Procedimiento para la obtencion de peptidos
ATE338059T1 (de) Reinigung von echinocandin cyclopeptiden
DE69434839D1 (de) Transferrin-rezeptor gene von haemophilus
KR880701246A (ko) 재조합 페포 계면활성제 단백질
Walker et al. The keratin chains of avian scale tissue: sequence heterogeneity and the number of scale keratin genes
EP0205555B2 (de) Serinproteaseinhibitoren und isolierungsverfahren dazu
Schneiderman et al. Isolation and partial characterization of structural protein derived from human red cell membranes
ATE195954T1 (de) Antibiotisches cryptdinpeptid und anwendungsmethoden
DE69837265D1 (de) Polypeptide zur regenerierung des nervensystems
AU1646892A (en) Production of phosphopeptides from casein
HUT76835A (en) Process for producing pharmaceuticals for treatment of anxiety and panic and gabapentin binding protein
Martenson et al. Isolation and identification of large overlapping fragments of rabbit myelin basic protein produced by limited peptic hydrolysis
DE69633179D1 (de) Transferrinrezeptorgene
DK595187A (da) Minactivin og fremgangsmaade til fremstilling deraf
Reichelt et al. Isolation of a growth and mitosis inhibitory peptide from mouse liver
US4784988A (en) Peptides correlated to lysozyme
ATE282088T1 (de) Aminopeptidase, welche von bacillus licheniformis abstammt und verfahren zur herstellung von proteinen des natürlichen typs
Wikler et al. The Amino Acid Sequence of a λ Type Bence-Jones Protein: II. CHYMOTRYPTIC PEPTIDES
JP2632526B2 (ja) 新規ペプチド

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties