ATE268777T1 - Langwelligabsorbierende bacteriochlorin-alkyl- aether- analoge - Google Patents
Langwelligabsorbierende bacteriochlorin-alkyl- aether- analogeInfo
- Publication number
- ATE268777T1 ATE268777T1 AT01108984T AT01108984T ATE268777T1 AT E268777 T1 ATE268777 T1 AT E268777T1 AT 01108984 T AT01108984 T AT 01108984T AT 01108984 T AT01108984 T AT 01108984T AT E268777 T1 ATE268777 T1 AT E268777T1
- Authority
- AT
- Austria
- Prior art keywords
- carbon atoms
- alkyl
- bacteriochlorine
- aether
- analogue
- Prior art date
Links
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical class CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 9
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Shielding Devices Or Components To Electric Or Magnetic Fields (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/592,150 US6624187B1 (en) | 2000-06-12 | 2000-06-12 | Long wave length absorbing bacteriochlorin alkyl ether analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268777T1 true ATE268777T1 (de) | 2004-06-15 |
Family
ID=24369506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01108984T ATE268777T1 (de) | 2000-06-12 | 2001-04-11 | Langwelligabsorbierende bacteriochlorin-alkyl- aether- analoge |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6624187B1 (de) |
| EP (1) | EP1164136B1 (de) |
| JP (1) | JP4976618B2 (de) |
| AT (1) | ATE268777T1 (de) |
| AU (1) | AU2984401A (de) |
| CA (1) | CA2342064C (de) |
| DE (1) | DE60103697T2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE39094E1 (en) | 1988-07-20 | 2006-05-09 | Health Research, Inc. | Pyropheophorbides and their use in photodynamic therapy |
| USRE38994E1 (en) | 1988-07-20 | 2006-02-28 | Health Research, Inc. | Pyropheophorbides conjugates and their use in photodynamic therapy |
| US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| AU737650B2 (en) * | 1997-11-03 | 2001-08-23 | Duke University | Substituted porphyrins |
| US6602274B1 (en) | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
| WO2000041725A2 (en) * | 1999-01-15 | 2000-07-20 | Light Sciences Corporation | Therapeutic compositions for metabolic bone disorders or bone metastases |
| WO2000041726A2 (en) | 1999-01-15 | 2000-07-20 | Light Sciences Corporation | Noninvasive vascular therapy |
| ATE552260T1 (de) | 1999-01-25 | 2012-04-15 | Nat Jewish Health | Substituierte porphyrine und deren therapeutische verwendung |
| US7897140B2 (en) * | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
| US7166719B2 (en) | 2002-06-27 | 2007-01-23 | Health Research, Inc. | Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy |
| EP1267935A2 (de) * | 2000-01-12 | 2003-01-02 | Light Sciences Corporation | Behandlung von augenerkrankungen |
| US6624187B1 (en) | 2000-06-12 | 2003-09-23 | Health Research, Inc. | Long wave length absorbing bacteriochlorin alkyl ether analogs |
| US20030069281A1 (en) * | 2000-06-14 | 2003-04-10 | Irwin Fridovich | Tetrapyrroles |
| US20030050297A1 (en) | 2001-01-19 | 2003-03-13 | Crapo James D. | Cancer therapy |
| EP1439842A4 (de) * | 2001-06-01 | 2009-09-02 | Nat Jewish Med & Res Center | Oxidantienfänger zur behandlung von diabetes oder zur verwendung bei der transplantation oder induktion von immuntoleranz |
| US7041121B1 (en) * | 2002-01-31 | 2006-05-09 | Medtronicvidamed, Inc. | Apparatus for treating prostate cancer and method for same |
| US7485721B2 (en) | 2002-06-07 | 2009-02-03 | Duke University | Substituted porphyrins |
| US7053210B2 (en) | 2002-07-02 | 2006-05-30 | Health Research, Inc. | Efficient synthesis of pyropheophorbide a and its derivatives |
| IL152900A0 (en) * | 2002-11-17 | 2003-06-24 | Yeda Res & Dev | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
| CA2602378C (en) | 2005-03-28 | 2014-01-28 | The Lubrizol Corporation | Titanium compounds and complexes as additives in lubricants |
| KR20090108071A (ko) * | 2007-01-09 | 2009-10-14 | 헬스 리서치 인코포레이티드 | 광역학 치료를 이용한 식도의 고 등급 형성이상증의 치료 |
| JP5608644B2 (ja) | 2008-05-23 | 2014-10-15 | ナショナル ジューイッシュ ヘルス | アルキル化種の被爆に関連する損傷の処置方法 |
| GB0819594D0 (en) | 2008-10-24 | 2008-12-03 | Univ Coimbrra | Process |
| CA2792665A1 (en) | 2010-03-10 | 2011-09-15 | The Lubrizol Corporation | Titanium and molybdenum compounds and complexes as additives in lubricants |
| CN111171030B (zh) * | 2018-11-12 | 2022-11-22 | 浙江海正药业股份有限公司 | 细菌叶绿素衍生物及其制备方法 |
| CN110904016A (zh) * | 2019-12-31 | 2020-03-24 | 内蒙古工业大学 | 一株重离子诱变类球红细菌高产辅酶q10的菌株及其应用 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4649151A (en) | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
| AU581840B2 (en) | 1982-09-27 | 1989-03-09 | Health Research Inc. | Porphyrin derivatives |
| US4753958A (en) | 1985-02-07 | 1988-06-28 | University Of Cal | Photochemotherapy of epithelial diseases with derivatives of hematoporphyrins |
| US4883790A (en) | 1987-01-20 | 1989-11-28 | University Of British Columbia | Wavelength-specific cytotoxic agents |
| US4968715A (en) | 1988-07-06 | 1990-11-06 | Health Research, Inc. | Use of purified hematoporphyrin trimers in photodynamic therapy |
| US5190966A (en) | 1988-07-06 | 1993-03-02 | Health Research, Inc. | Purified hematoporphyrin dimers and trimers useful in photodynamic therapy |
| US5002962A (en) | 1988-07-20 | 1991-03-26 | Health Research, Inc. | Photosensitizing agents |
| US5093349A (en) | 1988-07-20 | 1992-03-03 | Health Research Inc. | Photosensitizing agents |
| US5198460A (en) | 1988-07-20 | 1993-03-30 | Health Research Inc. | Pyropheophorbides and their use in photodynamic therapy |
| US5111821A (en) | 1988-11-08 | 1992-05-12 | Health Research, Inc. | Fluorometric method for detecting abnormal tissue using dual long-wavelength excitation |
| US5173504A (en) | 1989-04-21 | 1992-12-22 | Health Research, Inc. | Bacteriochlorophyll-a derivatives useful in photodynamic therapy |
| US5171741A (en) | 1989-04-21 | 1992-12-15 | Health Research, Inc. | Bacteriochlorophyll-a derivatives useful in photodynamic therapy |
| EP0510007B1 (de) | 1990-01-08 | 1996-05-08 | Health Research, Inc. | Tauchanordnung mit linse und optischer faser |
| US5074632A (en) | 1990-03-07 | 1991-12-24 | Health Research, Inc. | Fiber optic diffusers and methods for manufacture of the same |
| US5330741A (en) | 1992-02-24 | 1994-07-19 | The Regents Of The University Of California | Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors |
| US5257970A (en) | 1992-04-09 | 1993-11-02 | Health Research, Inc. | In situ photodynamic therapy |
| US5817830A (en) | 1992-08-14 | 1998-10-06 | Trustees Of The University Of Pennsylvania | Pyrrolic compounds |
| US5286474A (en) | 1992-10-22 | 1994-02-15 | Arizona Board Of Regents, A Body Corporate, Acting For And On Behalf The Arizona State University | Use of carotenoporphyrins as tumor localizing agents for diagnosis |
| DE4310643A1 (de) * | 1993-04-01 | 1994-10-06 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| DE4427979A1 (de) * | 1993-11-15 | 1996-02-15 | Cassella Ag | Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung |
| US5498710A (en) | 1994-04-22 | 1996-03-12 | Health Research, Inc. | Alkyl ether analogues of benzoporphyrin derivatives |
| US5591847A (en) | 1994-05-23 | 1997-01-07 | Health Research, Inc. | Long wavelength absorbing photosensitizers related to purpurin-18, bacteriopurpurin-18 and related compounds with imide linkages |
| US5591855A (en) | 1994-10-14 | 1997-01-07 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5576013A (en) | 1995-03-21 | 1996-11-19 | Eastern Virginia Medical School | Treating vascular and neoplastic tissues |
| US5637608A (en) | 1995-04-06 | 1997-06-10 | Cytopharm, Inc. | 9-substituted porphycenes |
| WO1997026885A1 (en) | 1996-01-23 | 1997-07-31 | The General Hospital Corporation Doing Business As Massachusetts General Hospital | Benzophenothiazine and benzoporphyrin dye combination photodynamic therapy of tumors |
| US5770730A (en) | 1996-03-08 | 1998-06-23 | Health Research, Inc. | Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer |
| US5952366A (en) | 1996-03-08 | 1999-09-14 | Health Research, Inc. | Alkyl ether analogs of chlorins having an N-substituted imide ring |
| US5671317A (en) | 1996-07-16 | 1997-09-23 | Health Research, Inc. | Fiber optic positioner |
| US5824657A (en) | 1997-03-18 | 1998-10-20 | Cubist Pharmaceuticals, Inc. | Aminoacyl sulfamides for the treatment of hyperproliferative disorders |
| DE19743903A1 (de) | 1997-07-16 | 1999-04-15 | Deutsch Zentr Luft & Raumfahrt | Verwendung von metallierten und/oder unmetallierten polymergebundenen Porphyrinen |
| US6071944A (en) | 1997-11-12 | 2000-06-06 | Bowling Green State University | Method of treatment of pigmented cancer cells utilizing photodynamic therapy |
| US6183727B1 (en) | 1998-05-19 | 2001-02-06 | Arizona Board Of Regents | Use of long-wavelength electromagnetic radiation and photoprotective tumor localizing agents for diagnosis |
| IN190482B (de) | 1998-05-20 | 2003-08-02 | M S Stoplik Services India Pvt | |
| US6103751A (en) | 1998-06-22 | 2000-08-15 | Health Research, Inc. | Carotene analogs of porphyrins, chlorins and bacteriochlorins as therapeutic and diagnostic agents |
| US6144185A (en) | 1999-03-22 | 2000-11-07 | Johnson Controls Technology Company | Method and apparatus for determining the condition of a battery through the use of multiple battery tests |
| WO2000061584A1 (en) | 1999-04-14 | 2000-10-19 | The University Of British Columbia | IMPROVED β,β,-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, AND BACTERIOCHLORINS |
| US6534040B2 (en) | 1999-12-23 | 2003-03-18 | Health Research, Inc. | Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals |
| US6624187B1 (en) | 2000-06-12 | 2003-09-23 | Health Research, Inc. | Long wave length absorbing bacteriochlorin alkyl ether analogs |
| JP2002097424A (ja) | 2000-09-08 | 2002-04-02 | Three M Innovative Properties Co | 熱硬化型導電性接着シート、それを用いた接続構造及び接続方法 |
| US6849607B2 (en) | 2001-05-09 | 2005-02-01 | Health Research, Inc. | Galectin recognized photosensitizers for photodynamic therapy |
-
2000
- 2000-06-12 US US09/592,150 patent/US6624187B1/en not_active Expired - Lifetime
-
2001
- 2001-03-21 CA CA2342064A patent/CA2342064C/en not_active Expired - Lifetime
- 2001-03-23 AU AU29844/01A patent/AU2984401A/en not_active Abandoned
- 2001-04-11 DE DE60103697T patent/DE60103697T2/de not_active Expired - Lifetime
- 2001-04-11 EP EP01108984A patent/EP1164136B1/de not_active Expired - Lifetime
- 2001-04-11 AT AT01108984T patent/ATE268777T1/de not_active IP Right Cessation
- 2001-04-16 JP JP2001116889A patent/JP4976618B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4976618B2 (ja) | 2012-07-18 |
| US6624187B1 (en) | 2003-09-23 |
| EP1164136B1 (de) | 2004-06-09 |
| DE60103697D1 (de) | 2004-07-15 |
| EP1164136A1 (de) | 2001-12-19 |
| JP2002020389A (ja) | 2002-01-23 |
| DE60103697T2 (de) | 2005-06-09 |
| CA2342064A1 (en) | 2001-12-12 |
| CA2342064C (en) | 2011-05-24 |
| AU2984401A (en) | 2001-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |