ATE268811T1 - Therapeutische anwendungen von chimänischer organogenese - Google Patents

Therapeutische anwendungen von chimänischer organogenese

Info

Publication number
ATE268811T1
ATE268811T1 AT94902570T AT94902570T ATE268811T1 AT E268811 T1 ATE268811 T1 AT E268811T1 AT 94902570 T AT94902570 T AT 94902570T AT 94902570 T AT94902570 T AT 94902570T AT E268811 T1 ATE268811 T1 AT E268811T1
Authority
AT
Austria
Prior art keywords
cells
chimeric
autologous
epithelium
allogeneic
Prior art date
Application number
AT94902570T
Other languages
English (en)
Inventor
F A Auger
Chemin Sainte-Foy Sacrement
M Rouabhia
L Lafleur
L Germain
Original Assignee
Univ Laval
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Laval filed Critical Univ Laval
Application granted granted Critical
Publication of ATE268811T1 publication Critical patent/ATE268811T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/16—Magnesium; Mg chelators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915—Method or apparatus for preparing biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT94902570T 1993-01-21 1993-12-21 Therapeutische anwendungen von chimänischer organogenese ATE268811T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/007,318 US5610007A (en) 1993-01-21 1993-01-21 Chimeric sheets of epithelial cells
PCT/CA1993/000546 WO1994017179A1 (en) 1993-01-21 1993-12-21 Therapeutic applications of chimeric organogenesis

Publications (1)

Publication Number Publication Date
ATE268811T1 true ATE268811T1 (de) 2004-06-15

Family

ID=21725473

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94902570T ATE268811T1 (de) 1993-01-21 1993-12-21 Therapeutische anwendungen von chimänischer organogenese

Country Status (7)

Country Link
US (1) US5610007A (de)
EP (1) EP0681608B1 (de)
JP (1) JP3748882B2 (de)
AT (1) ATE268811T1 (de)
DE (1) DE69333547T2 (de)
NZ (1) NZ258838A (de)
WO (1) WO1994017179A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1062322A2 (de) * 1998-02-24 2000-12-27 Advanced Tissue Sciences, Inc. Lebender chimärer hautersatz
US6964869B2 (en) * 1998-07-13 2005-11-15 Wisconsin Alumni Research Foundation Method and composition for skin grafts
US20060030044A1 (en) * 1998-07-13 2006-02-09 Allen-Hoffmann B Lynn Method and composition for skin grafts
AU1472501A (en) * 1999-11-05 2001-05-14 Gerigene Medical Corporation Augmentation and repair of age-related soft tissue defects
US20020039788A1 (en) * 2000-02-29 2002-04-04 Isseroff Roslyn R. Corneal epithelial graft composites
NZ529035A (en) * 2001-04-24 2007-01-26 Wisconsin Alumni Res Found Chimeric skin comprised of human immortalised keratinocyte cells and human donor cells for use in skin grafting and plastic surgery methods
ES2353380T3 (es) * 2002-04-24 2011-03-01 Organogenesis, Inc. Método para preparar construcciones de tejidos.
TW558677B (en) * 2002-08-02 2003-10-21 Chih-Hao Yiu Device for detecting angular position
AU300232S (en) 2004-06-17 2004-11-18 Hardie James Technology Ltd Trim system component
WO2006003818A1 (ja) * 2004-06-30 2006-01-12 Alblast Co., Ltd. 角膜上皮シート及びその作製方法
CN101912636B (zh) * 2010-05-19 2014-03-19 郭爱华 迷你皮肤结构及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769317A (en) * 1983-06-14 1988-09-06 Hefton John M Process for growing human epidermis, product thereof
FR2589165B1 (fr) * 1985-10-24 1989-01-20 Inst Nat Sante Rech Med Procede d'obtention d'un epithelium humain de culture, tissu epithelial obtenu et son application aux allogreffes
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
CA2000181A1 (en) * 1988-10-14 1990-04-14 Chung-Faye Chao Process for producing cultured epidermal sheet, product and method of use
IL94611A (en) * 1989-06-05 1994-12-29 Organogenesis Inc Medium for cell cultures containing insulin or growth factor similar to insulin, transferrin or iron ion, triiodothyronine or thyroxine and method of use
JPH04501510A (ja) * 1989-07-25 1992-03-19 セル ジェネシス,インコーポレイティド 普遍的なドナー細胞及びキメラ性哺乳類宿主のための相同性組換え
RU2135191C1 (ru) * 1990-04-24 1999-08-27 Ортек Интернэшнл, Инк. Композиционный эквивалент живой кожи, способ его получения, тест-набор

Also Published As

Publication number Publication date
EP0681608A1 (de) 1995-11-15
AU682485B2 (en) 1997-10-09
DE69333547T2 (de) 2005-08-18
AU5690594A (en) 1994-08-15
JPH08508876A (ja) 1996-09-24
EP0681608B1 (de) 2004-06-09
JP3748882B2 (ja) 2006-02-22
NZ258838A (en) 1998-03-25
WO1994017179A1 (en) 1994-08-04
DE69333547D1 (de) 2004-07-15
US5610007A (en) 1997-03-11

Similar Documents

Publication Publication Date Title
Llames et al. Human plasma as a dermal scaffold for the generation of a completely autologous bioengineered skin
Kumagai et al. Clinical application of autologous cultured epithelia for the treatment of burn wounds and burn scars
HUP9900920A2 (hu) Eljárás emlőssejt-tenyészetekben termelt proteinek szializációjának szabályozására
Navsaria et al. Culturing skin in vitro for wound therapy
ES2160116T3 (es) Modelo de equivalente de cornea producido in vitro.
PT633929E (pt) Metodo para proliferacao (in vitro) de precursores de celulas dentifricas e sua utilizacao para produzir imunogenios
CA2387542A1 (en) Supernatant from mesenchymal stem cells for prevention and treatment of immune responses in transplantation
UA81398C2 (en) Keratinocytes which may be used as biologically active substances for the treatment of wounds
DE69333547D1 (de) Therapeutische anwendungen von chimänischer organogenese
ATE320483T1 (de) Isolierung und züchtung von schwannzellen
DE69414572D1 (de) Immortalisierung von dendritischen zellen mit dem v-myc onkogen
ATE112317T1 (de) Bcrf1-proteine als inhibitoren von interferon- g(g).
DE60120676D1 (de) Verfahren zur entwicklung von epithelialen stammzellen
HUP9801629A2 (hu) Eljárások és készítmények CD28-expresszió szabályozására
WO2001094551A3 (de) Gen-modifizierte t-zellen, verfahren zu ihrer herstellung und ihre verwendung
Fioretti et al. Human bone marrow‐derived cells: An attractive source to populate dermal substitutes
CA2154368A1 (en) Therapeutic applications of chimeric organogenesis
EP0684831A4 (de) Allogenes vakzin und synthesemethode für selbiges.
AU6733896A (en) Transferrin glycans composition for the induction of immune tolerance
DE60132466D1 (de) Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen
Rouabhia et al. Successful transplantation of chimeric allogeneic-autologous cultured epithelium
CA2444699A1 (en) Method and composition for skin grafts
Breidahl et al. Variable rejection patterns of cultured keratinocyte allografts in the rabbit
Stokking et al. Three-dimensional-printed collagen scaffold with limbal stem cells derived from adipose-derived mesenchymal stem cells for the treatment of limbal stem cell deficiency
ATE326526T1 (de) Verfahren zur herstellung von neuronalem zellmaterial

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties