ATE269308T1 - Herstellung von 3-chloromethylpyridinhydrochlorid - Google Patents
Herstellung von 3-chloromethylpyridinhydrochloridInfo
- Publication number
- ATE269308T1 ATE269308T1 AT99952196T AT99952196T ATE269308T1 AT E269308 T1 ATE269308 T1 AT E269308T1 AT 99952196 T AT99952196 T AT 99952196T AT 99952196 T AT99952196 T AT 99952196T AT E269308 T1 ATE269308 T1 AT E269308T1
- Authority
- AT
- Austria
- Prior art keywords
- chloromethylpyridine
- thionyl chloride
- solution
- chloromethylpyridine hydrochloride
- production
- Prior art date
Links
- UZGLOGCJCWBBIV-UHFFFAOYSA-N 3-(chloromethyl)pyridin-1-ium;chloride Chemical compound Cl.ClCC1=CC=CN=C1 UZGLOGCJCWBBIV-UHFFFAOYSA-N 0.000 title abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 4
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- MVQVNTPHUGQQHK-UHFFFAOYSA-N 3-pyridinemethanol Chemical compound OCC1=CC=CN=C1 MVQVNTPHUGQQHK-UHFFFAOYSA-N 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229960004738 nicotinyl alcohol Drugs 0.000 abstract 2
- JPMRGPPMXHGKRO-UHFFFAOYSA-N 2-(chloromethyl)pyridine hydrochloride Chemical class Cl.ClCC1=CC=CC=N1 JPMRGPPMXHGKRO-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000012450 pharmaceutical intermediate Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000010926 purge Methods 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/187,402 US5942625A (en) | 1998-11-06 | 1998-11-06 | Preparation of chloromethylpyridine hydrochlorides |
| PCT/CA1999/001005 WO2000027818A1 (en) | 1998-11-06 | 1999-10-29 | Preparation of chloromethylpyridine hydrochlorides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE269308T1 true ATE269308T1 (de) | 2004-07-15 |
Family
ID=22688835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99952196T ATE269308T1 (de) | 1998-11-06 | 1999-10-29 | Herstellung von 3-chloromethylpyridinhydrochlorid |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5942625A (de) |
| EP (1) | EP1124803B1 (de) |
| AT (1) | ATE269308T1 (de) |
| AU (1) | AU6456699A (de) |
| CA (1) | CA2347374C (de) |
| DE (1) | DE69918157D1 (de) |
| HK (1) | HK1039934A1 (de) |
| MX (1) | MXPA01004527A (de) |
| WO (1) | WO2000027818A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105085377A (zh) * | 2015-09-07 | 2015-11-25 | 陈吉美 | 一种3-氯甲基吡啶盐酸盐的合成方法 |
| CN105085378A (zh) * | 2015-09-07 | 2015-11-25 | 陈吉美 | 一种4-氯甲基吡啶盐酸盐的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5521316A (en) * | 1994-05-20 | 1996-05-28 | Cytec Technology Corp. | Chloroalkyl pyridinum hydrochloride compounds and processes for their preparation |
-
1998
- 1998-11-06 US US09/187,402 patent/US5942625A/en not_active Expired - Fee Related
-
1999
- 1999-10-29 EP EP99952196A patent/EP1124803B1/de not_active Expired - Lifetime
- 1999-10-29 HK HK02101282.3A patent/HK1039934A1/zh unknown
- 1999-10-29 DE DE69918157T patent/DE69918157D1/de not_active Expired - Lifetime
- 1999-10-29 AT AT99952196T patent/ATE269308T1/de not_active IP Right Cessation
- 1999-10-29 AU AU64566/99A patent/AU6456699A/en not_active Abandoned
- 1999-10-29 MX MXPA01004527A patent/MXPA01004527A/es not_active IP Right Cessation
- 1999-10-29 CA CA002347374A patent/CA2347374C/en not_active Expired - Fee Related
- 1999-10-29 WO PCT/CA1999/001005 patent/WO2000027818A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01004527A (es) | 2002-09-18 |
| CA2347374A1 (en) | 2000-05-18 |
| US5942625A (en) | 1999-08-24 |
| EP1124803A1 (de) | 2001-08-22 |
| AU6456699A (en) | 2000-05-29 |
| WO2000027818A1 (en) | 2000-05-18 |
| CA2347374C (en) | 2004-11-23 |
| HK1039934A1 (zh) | 2002-05-17 |
| DE69918157D1 (de) | 2004-07-22 |
| EP1124803B1 (de) | 2004-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |