ATE269356T1 - Mutierte gewebefaktor-inhibitor (tfpi), dna sequenz davon und verwendung zur erkennung von thrombotischen erkrankungen - Google Patents

Mutierte gewebefaktor-inhibitor (tfpi), dna sequenz davon und verwendung zur erkennung von thrombotischen erkrankungen

Info

Publication number
ATE269356T1
ATE269356T1 AT99944432T AT99944432T ATE269356T1 AT E269356 T1 ATE269356 T1 AT E269356T1 AT 99944432 T AT99944432 T AT 99944432T AT 99944432 T AT99944432 T AT 99944432T AT E269356 T1 ATE269356 T1 AT E269356T1
Authority
AT
Austria
Prior art keywords
tfpi
dna sequence
tissue factor
thrombotic diseases
factor inhibitor
Prior art date
Application number
AT99944432T
Other languages
English (en)
Inventor
Knut Kleesiek
Thomas Brinkmann
Wolfgang Prohaska
Christian Goetting
Michael Schmidt
Original Assignee
Kleesiek Knut Prof Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kleesiek Knut Prof Dr filed Critical Kleesiek Knut Prof Dr
Application granted granted Critical
Publication of ATE269356T1 publication Critical patent/ATE269356T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT99944432T 1998-08-25 1999-08-18 Mutierte gewebefaktor-inhibitor (tfpi), dna sequenz davon und verwendung zur erkennung von thrombotischen erkrankungen ATE269356T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98115957 1998-08-25
PCT/EP1999/006054 WO2000011034A1 (en) 1998-08-25 1999-08-18 A mutant of tissue factor pathway inhibitor, dna sequence and use for detecting thrombotic disorders

Publications (1)

Publication Number Publication Date
ATE269356T1 true ATE269356T1 (de) 2004-07-15

Family

ID=8232503

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99944432T ATE269356T1 (de) 1998-08-25 1999-08-18 Mutierte gewebefaktor-inhibitor (tfpi), dna sequenz davon und verwendung zur erkennung von thrombotischen erkrankungen

Country Status (7)

Country Link
US (1) US6521410B1 (de)
EP (1) EP1105423B1 (de)
AT (1) ATE269356T1 (de)
AU (1) AU5736899A (de)
CA (1) CA2340460A1 (de)
DE (1) DE69918128T2 (de)
WO (1) WO2000011034A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436302B1 (en) * 1999-08-23 2002-08-20 Applied Materials, Inc. Post CU CMP polishing for reduced defects
CA2546171A1 (en) 2003-11-17 2005-05-26 Tm Bioscience Corporation Method of detecting mutations associated with thrombosis
WO2006066960A1 (en) * 2004-12-23 2006-06-29 Ludwig-Maximilians- Universität München Variant tfpi with increased anti-thrombotic activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104324A0 (en) * 1992-01-07 1993-05-13 Novo Nordisk As Variant of human kunitz-type protease inhibitor
US5589359A (en) * 1994-08-05 1996-12-31 Chiron Corporation Chimeric proteins

Also Published As

Publication number Publication date
WO2000011034A1 (en) 2000-03-02
US6521410B1 (en) 2003-02-18
EP1105423A1 (de) 2001-06-13
CA2340460A1 (en) 2000-03-02
DE69918128T2 (de) 2005-07-14
DE69918128D1 (de) 2004-07-22
EP1105423B1 (de) 2004-06-16
AU5736899A (en) 2000-03-14

Similar Documents

Publication Publication Date Title
DE69132352D1 (de) Protein-antagonisten der blut-koagulation und ihre verwendung
CY1119263T1 (el) Συνθεσεις και μεθοδοι για την αυξηση της ασβεστοποιησεως των οστων
DK1140969T3 (da) Bindevævsvækstfaktorfragmenter og fremgangsmåder og anvendelser deraf
EP1687283A4 (de) Für die bestimmung von fk506 geeignetes verfahren und zusammensetzung
ATE382053T1 (de) System zur antikörperexpression und- synthese
ATE356607T1 (de) Verwendung von nativem zein zur verbesserung des haarzustandes und mittel
ATE266675T1 (de) Troponin untereinheiten und fragmente zur verwendung als inhibitoren der angiogenese
EP1539228A4 (de) Neue zusammensetzung und verfahren zur behandlung von immunerkrankungen
DE60230029D1 (de) Immunisierungstherapie zur behandlung von atherosklerose
ATE490275T1 (de) Antikörper gegen interleukin-22 und verwendungen dafür
DE69918687D1 (de) 4-phenylpiperidine zur behandlung von prutitischen hauterkrankungen
ATE354638T1 (de) Menschlicher gewebsinhibitor von metalloproteinase-4
DE69822307D1 (de) Menschliches adamts-1 protein, gen , welches für dieses kodiert, pharmazeutische zusammensetzung und verfahrem zur immunologischen bestimmung von menschlichen adamts-1 proteinen
SE8902532D0 (sv) Bestaemning av plasmaproteiner
WO2005056585A3 (en) Sars coronavirus s proteins and uses thereof
DE69932845D1 (de) Methoden zur quantifizierung von hla-dr und cd11b
ATE209684T1 (de) Dna-sequenzen für matrix-metallproteasen, ihre herstellung und verwendung
DK0845943T3 (da) Nye peptider afledt fra humant heat shock protein 60 til behandling af diabetes, sammensætninger, fremgangsmåder og kits
ATE171473T1 (de) Humanisierte monoklonale antikörper gegen humanes interleukin - 4
DE69918128D1 (de) Mutierte gewebefaktor-inhibitor (tfpi), dna sequenz davon und verwendung zur erkennung von thrombotischen erkrankungen
CY1105380T1 (el) Προτιμωμενα τμηματα της νευρικης νηματικης πρωτεϊνης και μεθοδοι χρησης αυτων
DE60217079D1 (de) Nachweis und quantifizierung von cripto-1
WO2001074904A3 (en) G-protein coupled receptors and nucleic acids encoding same
DE69734890D1 (de) Rdgb-proteine
DK0870036T3 (da) Syntetisk pattedyrs-alfa-N-acetylglucosaminidase og genetiske sekvenser kodende derfor

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1105423

Country of ref document: EP

REN Ceased due to non-payment of the annual fee