ATE271047T1 - Type 1 inhibitorkristalle als inhibitoren des natrium-protonen austauschs - Google Patents

Type 1 inhibitorkristalle als inhibitoren des natrium-protonen austauschs

Info

Publication number
ATE271047T1
ATE271047T1 AT00962776T AT00962776T ATE271047T1 AT E271047 T1 ATE271047 T1 AT E271047T1 AT 00962776 T AT00962776 T AT 00962776T AT 00962776 T AT00962776 T AT 00962776T AT E271047 T1 ATE271047 T1 AT E271047T1
Authority
AT
Austria
Prior art keywords
inhibitors
sodium
type
proton exchange
inhibitor crystals
Prior art date
Application number
AT00962776T
Other languages
English (en)
Inventor
Lyle Robinson Brostrom
Terrence Joseph Connolly
Zheng Jane Li
Susan L Orrill
Bharat K Shah
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE271047T1 publication Critical patent/ATE271047T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
AT00962776T 1999-10-29 2000-10-09 Type 1 inhibitorkristalle als inhibitoren des natrium-protonen austauschs ATE271047T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16237499P 1999-10-29 1999-10-29
PCT/IB2000/001460 WO2001030759A2 (en) 1999-10-29 2000-10-09 Sodium-hydrogen exchanger type 1 inhibitor crystals

Publications (1)

Publication Number Publication Date
ATE271047T1 true ATE271047T1 (de) 2004-07-15

Family

ID=22585355

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00962776T ATE271047T1 (de) 1999-10-29 2000-10-09 Type 1 inhibitorkristalle als inhibitoren des natrium-protonen austauschs

Country Status (44)

Country Link
EP (1) EP1224179B1 (de)
JP (1) JP2003512455A (de)
KR (1) KR100464526B1 (de)
CN (2) CN1205205C (de)
AP (1) AP2002002493A0 (de)
AR (1) AR029402A1 (de)
AT (1) ATE271047T1 (de)
AU (1) AU778573B2 (de)
BG (1) BG106729A (de)
BR (1) BR0015275A (de)
CA (1) CA2389020A1 (de)
CO (1) CO5271714A1 (de)
CZ (1) CZ20021332A3 (de)
DE (1) DE60012208T2 (de)
DK (1) DK1224179T3 (de)
DZ (1) DZ3463A1 (de)
EA (1) EA004937B1 (de)
EE (1) EE200200227A (de)
ES (1) ES2222923T3 (de)
GE (1) GEP20043222B (de)
GT (1) GT200000180A (de)
HK (1) HK1048472B (de)
HR (1) HRP20020366B1 (de)
HU (1) HUP0204009A3 (de)
IL (1) IL148581A0 (de)
IS (1) IS6302A (de)
MA (1) MA26840A1 (de)
MX (1) MXPA02004358A (de)
NO (1) NO20021821L (de)
NZ (1) NZ517738A (de)
OA (1) OA12080A (de)
PA (1) PA8505501A1 (de)
PE (1) PE20010764A1 (de)
PL (1) PL354869A1 (de)
PT (1) PT1224179E (de)
SI (1) SI1224179T1 (de)
SK (1) SK5312002A3 (de)
SV (1) SV2002000209A (de)
TN (1) TNSN00210A1 (de)
TR (1) TR200201167T2 (de)
UA (1) UA72002C2 (de)
WO (1) WO2001030759A2 (de)
YU (1) YU31502A (de)
ZA (1) ZA200203295B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6441176B1 (en) 1999-10-29 2002-08-27 Pfizer Inc. Method for preparing sodium-hydrogen exchanger type 1 inhibitor
CA2436539A1 (en) * 2001-01-31 2002-08-08 Pfizer Products Inc. Ethanolates of sodium-hydrogen exchanger type-1 inhibitor
EP1472242A1 (de) * 2002-01-30 2004-11-03 Pfizer Products Inc. Pharmazeutische zusammensetzungen, zoniporide mesylat enthaltend und prozesse zur verbesserung der löslichkeit von zoniporide
CA2483927A1 (en) * 2002-05-02 2003-11-13 Pfizer Products Inc. Treatment of diabetes and diabetic complications with nhe-1 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002504546A (ja) * 1998-02-27 2002-02-12 ファイザー・プロダクツ・インク 虚血の治療のためのｎ−［（置換５員ジもしくはトリアザ二不飽和環）カルボニル］グアニジン誘導体

Also Published As

Publication number Publication date
IL148581A0 (en) 2002-09-12
DE60012208D1 (de) 2004-08-19
KR100464526B1 (ko) 2005-01-03
BG106729A (bg) 2002-12-29
EP1224179A2 (de) 2002-07-24
IS6302A (is) 2002-03-15
EA004937B1 (ru) 2004-10-28
YU31502A (sh) 2004-12-31
HK1048472B (zh) 2005-09-16
NO20021821D0 (no) 2002-04-18
CN1384829A (zh) 2002-12-11
HRP20020366B1 (en) 2005-04-30
TR200201167T2 (tr) 2002-08-21
UA72002C2 (en) 2005-01-17
OA12080A (en) 2003-08-25
NO20021821L (no) 2002-04-18
ZA200203295B (en) 2003-06-25
ES2222923T3 (es) 2005-02-16
PA8505501A1 (es) 2003-09-05
HRP20020366A2 (en) 2004-02-29
CA2389020A1 (en) 2001-05-03
AU7441500A (en) 2001-05-08
SK5312002A3 (en) 2003-01-09
SV2002000209A (es) 2002-07-16
BR0015275A (pt) 2002-07-16
CZ20021332A3 (cs) 2002-10-16
EA200200416A1 (ru) 2002-10-31
GEP20043222B (en) 2004-04-26
CN1636991A (zh) 2005-07-13
EP1224179B1 (de) 2004-07-14
PT1224179E (pt) 2004-10-29
DE60012208T2 (de) 2005-07-21
PL354869A1 (en) 2004-03-08
SI1224179T1 (en) 2004-10-31
GT200000180A (es) 2002-04-11
TNSN00210A1 (fr) 2005-11-10
DZ3463A1 (fr) 2001-05-03
WO2001030759A3 (en) 2001-09-13
PE20010764A1 (es) 2001-07-23
CO5271714A1 (es) 2003-04-30
MXPA02004358A (es) 2002-11-07
CN1205205C (zh) 2005-06-08
HK1048472A1 (en) 2003-04-04
MA26840A1 (fr) 2004-12-20
DK1224179T3 (da) 2004-10-25
NZ517738A (en) 2005-06-24
JP2003512455A (ja) 2003-04-02
WO2001030759A2 (en) 2001-05-03
EE200200227A (et) 2003-06-16
AR029402A1 (es) 2003-06-25
KR20020040918A (ko) 2002-05-30
HUP0204009A3 (en) 2004-07-28
AP2002002493A0 (en) 2002-06-30
HUP0204009A2 (hu) 2003-03-28
AU778573B2 (en) 2004-12-09

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