ATE271615T1 - Detektion von dns-schädigenden substanzen - Google Patents

Detektion von dns-schädigenden substanzen

Info

Publication number
ATE271615T1
ATE271615T1 AT98913889T AT98913889T ATE271615T1 AT E271615 T1 ATE271615 T1 AT E271615T1 AT 98913889 T AT98913889 T AT 98913889T AT 98913889 T AT98913889 T AT 98913889T AT E271615 T1 ATE271615 T1 AT E271615T1
Authority
AT
Austria
Prior art keywords
dna
damageing
substances
detection
regulatory element
Prior art date
Application number
AT98913889T
Other languages
English (en)
Inventor
Richard Maurice Walmsley
Wolf Dietrich Heyer
Original Assignee
Gentronix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10809987&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE271615(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gentronix Ltd filed Critical Gentronix Ltd
Application granted granted Critical
Publication of ATE271615T1 publication Critical patent/ATE271615T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5032Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on intercellular interactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT98913889T 1997-03-27 1998-03-27 Detektion von dns-schädigenden substanzen ATE271615T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9706414.1A GB9706414D0 (en) 1997-03-27 1997-03-27 Detection of DNA damage
PCT/GB1998/000786 WO1998044149A1 (en) 1997-03-27 1998-03-27 Detection of dna damaging agents

Publications (1)

Publication Number Publication Date
ATE271615T1 true ATE271615T1 (de) 2004-08-15

Family

ID=10809987

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98913889T ATE271615T1 (de) 1997-03-27 1998-03-27 Detektion von dns-schädigenden substanzen

Country Status (11)

Country Link
US (2) US6489099B1 (de)
EP (2) EP0970247B1 (de)
JP (1) JP4163757B2 (de)
AT (1) ATE271615T1 (de)
AU (1) AU747297B2 (de)
CA (1) CA2285703C (de)
DE (1) DE69825152T2 (de)
DK (1) DK0970247T3 (de)
ES (1) ES2226118T3 (de)
GB (1) GB9706414D0 (de)
WO (1) WO1998044149A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP438598A0 (en) 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
US6509161B1 (en) 2000-02-29 2003-01-21 Gentronix Limited Green fluorescent protein
JP2007500506A (ja) * 2003-07-31 2007-01-18 ジェントロニクス・リミテッド 遺伝子毒性試験法
GB0411198D0 (en) * 2004-05-20 2004-06-23 Gentronix Ltd Genotoxic testing
US8969008B2 (en) 2004-05-20 2015-03-03 Gentronix Limited Genotoxic testing
JP2006101705A (ja) * 2004-09-30 2006-04-20 Olympus Corp 細胞内小核の検出方法
US20080187927A1 (en) * 2006-11-12 2008-08-07 Palecek Sean P Using hug1 promoter and a reporter gene to detect genotoxicity and genoprotection
GB0921712D0 (en) 2009-12-11 2010-01-27 Ge Healthcare Uk Ltd Methods of detecting DNA damage
EP4069731A4 (de) 2019-12-03 2024-05-29 Alamar Biosciences, Inc. Nukleinsäure-gekoppelter immun-sandwich-assay (nulisa)
CN115575369B (zh) * 2022-10-14 2025-10-28 中国药科大学 一种用于消化道内亚硝胺类化合物监测的金属有机配位凝胶保护的全细胞生物传感器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL75210A0 (en) 1984-05-22 1985-09-29 Bioteknika International Yeast vector
HK1004920A1 (en) * 1993-01-21 1998-12-11 President And Fellows Of Harvard College Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound
EP0759170B1 (de) * 1993-09-10 2008-07-09 The Trustees Of Columbia University In The City Of New York Verwendung von grünem fluoreszenzprotein

Also Published As

Publication number Publication date
CA2285703A1 (en) 1998-10-08
DE69825152T2 (de) 2005-08-11
US20030049690A1 (en) 2003-03-13
DE69825152D1 (de) 2004-08-26
ES2226118T3 (es) 2005-03-16
CA2285703C (en) 2011-02-08
DK0970247T3 (da) 2004-11-29
WO1998044149A1 (en) 1998-10-08
US7049071B2 (en) 2006-05-23
EP0970247A1 (de) 2000-01-12
AU6841998A (en) 1998-10-22
AU747297B2 (en) 2002-05-16
US6489099B1 (en) 2002-12-03
JP4163757B2 (ja) 2008-10-08
EP0970247B1 (de) 2004-07-21
JP2001517083A (ja) 2001-10-02
EP1561822A1 (de) 2005-08-10
GB9706414D0 (en) 1997-05-14

Similar Documents

Publication Publication Date Title
ATE353965T1 (de) An g-protein gekoppelte rezeptoren und deren verwendungen
ATE332368T1 (de) Selektion von proteinen mittels rns-protein fusionen
EP1190043A4 (de) Glykoprotein vi und dessen anwendungen
ATE388165T1 (de) Menschliches cnp-gen und vorläuferprotein
ATE454393T1 (de) Egvii-endoglucanase und dafür codierende nukleinsäuren
DK0643767T3 (da) Osteogene peptider
BG100771A (bg) Хематопоетичен протеин и материали и методи за неговото получаване
ES2137931T3 (es) Proteinas gdf-1 y uog-1.
AR038568A1 (es) Anticuerpos anti-a beta y su uso
NL300137I1 (nl) Recombinante proteïnen van virussen geassocieerd met het
ATE271615T1 (de) Detektion von dns-schädigenden substanzen
DE69632827D1 (de) Materialen und methoden im zusammenhang mit bindung und präsentation von substanzen auf zelloberflächen
ATE438657T1 (de) Charakterisierung von granulozytischer ehrlichia und methoden für ihre verwendung.
DK0641861T3 (da) Fremgangsmåde til fremstilling af hydrofobe polypeptider, proteiner eller peptider
MXPA00002111A (es) Biomoleculas que contienen un peptido elastomerico.
DE60330489D1 (de) Schnell abgebaute reporter-fusionsproteine
DK1576157T3 (da) Fluorescerende proteiner fra Copepode-arter og fremgangsmåder til anvendelse af samme
DE60139113D1 (de) 18477, eine menschliche proteinkinase und deren verwendung
DK1012256T3 (da) Rekombinante fusionsproteiner på basis af ribosom-inaktiverende proteiner fra misteltenen Viscum album
DE59109235D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
DE69534738D1 (de) Leukocyten-aktivierender Faktor
CO5070672A1 (es) Polipeptido de proteina c humana
DK1328621T3 (da) 13245, en ny human proteinkinase af den myotoniske dystrofitype og anvendelser deraf
DE69613086D1 (de) Antigenen Peptide mit Glycinsubstitution
AR037939A1 (es) Receptor novedoso acoplado a la proteina g, gave7

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties