ATE271919T1 - Mikrodosier- und probennahmevorrichtung sowie mikrochip mit dieser vorrichtung - Google Patents

Mikrodosier- und probennahmevorrichtung sowie mikrochip mit dieser vorrichtung

Info

Publication number
ATE271919T1
ATE271919T1 AT02022888T AT02022888T ATE271919T1 AT E271919 T1 ATE271919 T1 AT E271919T1 AT 02022888 T AT02022888 T AT 02022888T AT 02022888 T AT02022888 T AT 02022888T AT E271919 T1 ATE271919 T1 AT E271919T1
Authority
AT
Austria
Prior art keywords
channel
wall
open
microchip
liquid
Prior art date
Application number
AT02022888T
Other languages
English (en)
Inventor
Minoru Seki
Masumi Yamada
Hisashi Hagiwara
Original Assignee
Aida Eng Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aida Eng Ltd filed Critical Aida Eng Ltd
Application granted granted Critical
Publication of ATE271919T1 publication Critical patent/ATE271919T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7172—Feed mechanisms characterised by the means for feeding the components to the mixer using capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/712—Feed mechanisms for feeding fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/714—Feed mechanisms for feeding predetermined amounts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71805—Feed mechanisms characterised by the means for feeding the components to the mixer using valves, gates, orifices or openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/7547—Discharge mechanisms characterised by the means for discharging the components from the mixer using valves, gates, orifices or openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/81—Forming mixtures with changing ratios or gradients
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0605—Valves, specific forms thereof check valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT02022888T 2001-10-18 2002-10-14 Mikrodosier- und probennahmevorrichtung sowie mikrochip mit dieser vorrichtung ATE271919T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001320592 2001-10-18
JP2002278924 2002-09-25

Publications (1)

Publication Number Publication Date
ATE271919T1 true ATE271919T1 (de) 2004-08-15

Family

ID=26623967

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02022888T ATE271919T1 (de) 2001-10-18 2002-10-14 Mikrodosier- und probennahmevorrichtung sowie mikrochip mit dieser vorrichtung

Country Status (5)

Country Link
US (1) US20030077204A1 (de)
EP (1) EP1304167B1 (de)
AT (1) ATE271919T1 (de)
CA (1) CA2408692C (de)
DE (1) DE60200822T2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002306486A1 (en) * 2001-02-09 2002-08-28 Microchem Solutions Method and apparatus for sample injection in microfabricated devices
DE20317944U1 (de) * 2003-11-18 2004-03-11 Heiser, Volker, Dr. Probenträger für Moleküle
EP1712916A4 (de) * 2003-12-26 2008-07-23 Matsushita Electric Industrial Co Ltd Vorrichtung zur unterscheidung biologischer proben, verfahren zur unterscheidung biologischer proben und platte zur unterscheidung biologischer proben
US7592185B2 (en) 2004-02-17 2009-09-22 Molecular Bioproducts, Inc. Metering doses of sample liquids
EP1832872A4 (de) * 2004-12-08 2009-07-29 Panasonic Corp Platte zur analyse biologischer proben
US9039273B2 (en) 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
WO2006108559A2 (de) * 2005-04-09 2006-10-19 Boehringer Ingelheim Microparts Gmbh Vorrichtung und verfahren zur untersuchung einer probenflüssigkeit
EP1717585B1 (de) * 2005-04-28 2013-01-16 FUJIFILM Corporation Mikrochip und Analyseverfahren unter Verwendung desselben
KR101159880B1 (ko) * 2006-03-09 2012-06-26 세키스이가가쿠 고교가부시키가이샤 마이크로 유체 디바이스 및 미량 액체 희석 방법
WO2008083687A1 (en) 2007-01-10 2008-07-17 Scandinavian Micro Biodevices Aps A microfluidic device and a microfluidic system and a method of performing a test
JP5052996B2 (ja) * 2007-08-22 2012-10-17 アイダエンジニアリング株式会社 電気泳動用マイクロ流路チップ及び電気泳動方法
WO2011028764A2 (en) 2009-09-02 2011-03-10 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
JP6122843B2 (ja) * 2011-05-23 2017-04-26 プレジデント アンド フェローズ オブ ハーバード カレッジ 多重エマルジョンを含むエマルジョンの制御
US20140220350A1 (en) 2011-07-06 2014-08-07 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
WO2013029159A1 (en) 2011-08-30 2013-03-07 The Royal Institution For The Advancement Of Learning / Mcgill University Method and system for pre-programmed self-power microfluidic circuits
US8986630B2 (en) 2012-06-08 2015-03-24 Sekisui Chemical Co., Ltd. Gas-generating material and micro pump
EP2902784B1 (de) 2012-09-28 2018-10-24 National Institute of Advanced Industrial Science and Technology Assayvorrichtung mit einem porösen medium
EP3132019A1 (de) * 2014-04-16 2017-02-22 The Charles Stark Draper Laboratory, Inc. Mikrofluidisches gewebemodell
CN106662595B (zh) 2014-06-30 2019-10-15 普和希控股公司 试样分析用基板、试样分析装置、试样分析系统及从含磁性颗粒的液体中去除液体的方法
EP3163306A4 (de) 2014-06-30 2018-01-24 Panasonic Healthcare Holdings Co., Ltd. Substrat zur probenanalyse und probenanalysevorrichtung
WO2016002729A1 (ja) 2014-06-30 2016-01-07 パナソニックヘルスケアホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
US10309976B2 (en) 2014-06-30 2019-06-04 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
US10539583B2 (en) 2014-12-12 2020-01-21 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
JP6924556B2 (ja) * 2016-04-12 2021-08-25 株式会社日立プラントサービス マイクロリアクタ、化成品製造システム及びマイクロリアクタの製造方法
US11185830B2 (en) 2017-09-06 2021-11-30 Waters Technologies Corporation Fluid mixer
US12241907B2 (en) 2019-04-22 2025-03-04 Sekisui Chemical Co., Ltd. Chip and fluid-merging method
CN112108192B (zh) * 2019-06-19 2022-03-22 中国科学院大连化学物理研究所 一种微流控芯片及其应用
WO2021030245A1 (en) 2019-08-12 2021-02-18 Waters Technologies Corporation Mixer for chromatography system
CN116134312B (zh) 2020-07-07 2025-12-02 沃特世科技公司 液相色谱用混合器
WO2022010666A1 (en) 2020-07-07 2022-01-13 Waters Technologies Corporation Combination mixer arrangement for noise reduction in fluid chromatography
CN116194767A (zh) 2020-09-22 2023-05-30 沃特世科技公司 连续流混合器
CN117355747A (zh) 2021-05-20 2024-01-05 沃特世科技公司 等分散分流混合器
CN117580636A (zh) 2021-06-23 2024-02-20 沃特世科技公司 用于液相色谱法的被动溶剂混合器
CN116651520A (zh) * 2023-05-08 2023-08-29 复旦大学 微流控芯片及微流控装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503803A (en) * 1988-03-28 1996-04-02 Conception Technologies, Inc. Miniaturized biological assembly
CA2258489C (en) * 1996-06-28 2004-01-27 Caliper Technologies Corporation High-throughput screening assay systems in microscale fluidic devices
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
US6235471B1 (en) * 1997-04-04 2001-05-22 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6117396A (en) * 1998-02-18 2000-09-12 Orchid Biocomputer, Inc. Device for delivering defined volumes
AU739563B2 (en) * 1998-03-11 2001-10-18 Boehringer Ingelheim Microparts Gmbh Sample support
CA2347182C (en) * 1998-10-13 2004-06-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
AU2002306486A1 (en) * 2001-02-09 2002-08-28 Microchem Solutions Method and apparatus for sample injection in microfabricated devices

Also Published As

Publication number Publication date
US20030077204A1 (en) 2003-04-24
EP1304167A1 (de) 2003-04-23
EP1304167B1 (de) 2004-07-28
DE60200822T2 (de) 2005-09-15
DE60200822D1 (de) 2004-09-02
CA2408692C (en) 2007-01-30
CA2408692A1 (en) 2003-04-18

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