ATE272224T1 - Konfokales spektroskopiesystem und -verfahren - Google Patents

Konfokales spektroskopiesystem und -verfahren

Info

Publication number
ATE272224T1
ATE272224T1 AT97120101T AT97120101T ATE272224T1 AT E272224 T1 ATE272224 T1 AT E272224T1 AT 97120101 T AT97120101 T AT 97120101T AT 97120101 T AT97120101 T AT 97120101T AT E272224 T1 ATE272224 T1 AT E272224T1
Authority
AT
Austria
Prior art keywords
light
illumination
light modulator
conjugate
light source
Prior art date
Application number
AT97120101T
Other languages
English (en)
Inventor
Thomas M Jovin
Quentin Hanley
Peter Verveer
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Application granted granted Critical
Publication of ATE272224T1 publication Critical patent/ATE272224T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/2823Imaging spectrometer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/10Arrangements of light sources specially adapted for spectrometry or colorimetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/457Correlation spectrometry, e.g. of the intensity
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036Scanning details, e.g. scanning stages
    • G02B21/004Scanning details, e.g. scanning stages fixed arrays, e.g. switchable aperture arrays
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0076Optical details of the image generation arrangements using fluorescence or luminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J2003/2866Markers; Calibrating of scan
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/021Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using plane or convex mirrors, parallel phase plates, or particular reflectors

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AT97120101T 1997-11-17 1997-11-17 Konfokales spektroskopiesystem und -verfahren ATE272224T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97120101A EP0916981B1 (de) 1997-11-17 1997-11-17 Konfokales Spektroskopiesystem und -verfahren

Publications (1)

Publication Number Publication Date
ATE272224T1 true ATE272224T1 (de) 2004-08-15

Family

ID=8227631

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97120101T ATE272224T1 (de) 1997-11-17 1997-11-17 Konfokales spektroskopiesystem und -verfahren

Country Status (5)

Country Link
US (1) US6128077A (de)
EP (1) EP0916981B1 (de)
JP (1) JP4712923B2 (de)
AT (1) ATE272224T1 (de)
DE (1) DE69730030T2 (de)

Families Citing this family (176)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7907319B2 (en) 1995-11-06 2011-03-15 Qualcomm Mems Technologies, Inc. Method and device for modulating light with optical compensation
US6421165B2 (en) * 1996-02-07 2002-07-16 Light & Sound Design Ltd. Programmable light beam shape altering device using programmable micromirrors
DE69806496T2 (de) 1997-10-29 2003-03-13 Macaulay, Calum E. Gerät und verfahren zur mikroskopie unter verwendung räumlich modulierten lichtes
US6388809B1 (en) 1997-10-29 2002-05-14 Digital Optical Imaging Corporation Methods and apparatus for improved depth resolution use of out-of-focus information in microscopy
WO1999052006A2 (en) 1998-04-08 1999-10-14 Etalon, Inc. Interferometric modulation of radiation
US8928967B2 (en) 1998-04-08 2015-01-06 Qualcomm Mems Technologies, Inc. Method and device for modulating light
DE19829981C2 (de) * 1998-07-04 2002-10-17 Zeiss Carl Jena Gmbh Verfahren und Anordnung zur konfokalen Mikroskopie
JP4270610B2 (ja) * 1998-09-24 2009-06-03 オリンパス株式会社 走査型光学顕微鏡
JP3440465B2 (ja) * 1998-12-17 2003-08-25 株式会社高岳製作所 マルチスリット走査撮像装置
US6859275B2 (en) * 1999-04-09 2005-02-22 Plain Sight Systems, Inc. System and method for encoded spatio-spectral information processing
US7219086B2 (en) 1999-04-09 2007-05-15 Plain Sight Systems, Inc. System and method for hyper-spectral analysis
DE19930532C2 (de) * 1999-06-30 2002-03-28 Zeiss Carl Jena Gmbh Anordnung zur Optimierung der Pulsform in einem Laser-Scanning-Mikroskop
EP1553402A3 (de) * 1999-07-30 2005-08-10 California Institute Of Technology System und Verfahren zur Überwachung von Zellulären Aktivität
US6403332B1 (en) 1999-07-30 2002-06-11 California Institute Of Technology System and method for monitoring cellular activity
JP4536986B2 (ja) * 1999-11-09 2010-09-01 レイセオン カンパニー 腫瘍からの同時多数マーカー放射(casmmen)に基づいた細胞解析を行う装置
US6663560B2 (en) * 1999-12-17 2003-12-16 Digital Optical Imaging Corporation Methods and apparatus for imaging using a light guide bundle and a spatial light modulator
US20020001089A1 (en) * 2000-04-18 2002-01-03 Price Jeffrey H. Multiparallel three dimensional optical microscopy system
DE20122791U1 (de) * 2000-06-17 2007-11-29 Leica Microsystems Cms Gmbh Scanmikroskop
DE10038528A1 (de) * 2000-08-08 2002-02-21 Zeiss Carl Jena Gmbh Verfahren und Anordnung zur Erhöhung der spektralen und räumlichen Detektorauflösung
JP2002062261A (ja) * 2000-08-21 2002-02-28 Olympus Optical Co Ltd 光学装置および顕微鏡
DE10044308A1 (de) * 2000-09-07 2002-03-21 Leica Microsystems Verfahren und Vorrichtung zur Detektion von Fluoreszenzlicht bei der konfokalen Rastermikroskopie
US6661509B2 (en) * 2001-02-07 2003-12-09 Thermo Electron Scientific Instruments Corporation Method and apparatus for alignment of multiple beam paths in spectroscopy
JP4610713B2 (ja) * 2000-10-13 2011-01-12 オリンパス株式会社 内視鏡装置
KR100378988B1 (ko) * 2000-10-27 2003-04-08 한국과학기술연구원 반도체 패키지의 삼차원 시각 검사방법
AU2007205778B2 (en) * 2001-02-02 2009-12-24 Tidal Photonics, Inc Apparatus and methods relating to wavelength conditioning of illumination
US6781691B2 (en) * 2001-02-02 2004-08-24 Tidal Photonics, Inc. Apparatus and methods relating to wavelength conditioning of illumination
US6934069B2 (en) 2001-04-03 2005-08-23 Cidra Corporation Chromatic dispersion compensation device having an array of micromirrors
US6956687B2 (en) * 2001-04-03 2005-10-18 Cidra Corporation Optical blocking filter having an array of micro-mirrors
EP1386192A2 (de) * 2001-04-03 2004-02-04 CiDra Corporation Dynamisches optisches filter mit einem räumlichen lichtmodulator
US6922277B2 (en) 2001-09-25 2005-07-26 Cidra Corporation Optical interleaver/deinterleaver device having an array of micro-mirrors
US7126740B2 (en) * 2001-04-03 2006-10-24 Cidra Corporation Multifunctional optical device having a spatial light modulator with an array of micromirrors
US20030090756A1 (en) * 2001-09-25 2003-05-15 Cidra Corporation Optical channel monitor having an array of micro-mirrors
US20020176149A1 (en) * 2001-04-03 2002-11-28 Michael Davis Variable optical source
DE10137158B4 (de) * 2001-07-30 2005-08-04 Leica Microsystems Heidelberg Gmbh Verfahren zur Scanmikroskopie und Scanmikroskop
WO2003025656A1 (en) * 2001-09-03 2003-03-27 Kabushiki Kaisha Hayashi Soken Digital control scanning method and apparatus
DE50212392D1 (de) * 2001-09-11 2008-07-31 Leica Microsystems Verfahren und vorrichtung zur optischen untersuchung eines objektes
WO2003028265A2 (en) * 2001-09-25 2003-04-03 Cidra Corporation Reconfigurable optical add/drop multiplexer having an array of micro-mirrors
JP5048899B2 (ja) * 2001-09-28 2012-10-17 オリンパス株式会社 顕微鏡
JP2005521123A (ja) * 2001-10-22 2005-07-14 ライカ ミクロジュステムス ヴェツラー ゲーエムベーハー 光学顕微鏡検出3次元画像の生成方法及び生成装置
IL146174A (en) * 2001-10-25 2007-08-19 Camtek Ltd Confocal system for testing woofers
US6885492B2 (en) 2001-11-08 2005-04-26 Imaginative Optics, Inc. Spatial light modulator apparatus
US6947127B2 (en) * 2001-12-10 2005-09-20 Carl Zeiss Jena Gmbh Arrangement for the optical capture of excited and/or back scattered light beam in a sample
GB0200819D0 (en) 2002-01-15 2002-03-06 Cole Polytechnique Federale De Microscopy imaging apparatus and method for generating an image
DE50307047D1 (de) * 2002-02-04 2007-05-31 Zeiss Carl Surgical Gmbh Stereo-Untersuchungssysteme und Stereo-Bilderzeugungsvorrichtung sowie Verfahren zum Betrieb einer solchen
FR2835829B1 (fr) * 2002-02-13 2007-09-14 Centre Nat Rech Scient Nouveau procede de preparation de biopuces a adn ou a proteines et leurs applications
US6996292B1 (en) 2002-04-18 2006-02-07 Sandia Corporation Staring 2-D hadamard transform spectral imager
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7399643B2 (en) 2002-09-12 2008-07-15 Cyvera Corporation Method and apparatus for aligning microbeads in order to interrogate the same
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7619819B2 (en) 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
EP1540591A1 (de) 2002-09-12 2005-06-15 Cyvera Corporation Mit hilfe eines beugungsgitters kodierte mikropartikeln für multiplex-experimente
US7391388B2 (en) * 2002-10-28 2008-06-24 Raytheon Company Segmented spectrum imaging system and method
FR2848682B1 (fr) 2002-12-13 2005-02-18 Commissariat Energie Atomique Microscope optique a eclairage structure modifiable
US7339148B2 (en) 2002-12-16 2008-03-04 Olympus America Inc. Confocal microscope
TWI289708B (en) 2002-12-25 2007-11-11 Qualcomm Mems Technologies Inc Optical interference type color display
US7001038B2 (en) 2003-01-10 2006-02-21 Bock Joel N Method and apparatus for object viewing, observation, inspection, identification, and verification
US6965431B2 (en) * 2003-02-28 2005-11-15 Ut-Battelle, Llc Integrated tunable optical sensor (ITOS) system
US7106435B2 (en) * 2003-03-17 2006-09-12 Drs Sensors & Targeting Systems, Inc. Hyperspectral scene generator and method of use
JP2004309702A (ja) * 2003-04-04 2004-11-04 Olympus Corp 顕微鏡
JP2005024596A (ja) * 2003-06-30 2005-01-27 Susumu Terakawa 共焦点走査顕微鏡
CA2581668A1 (en) * 2003-09-26 2005-04-07 Tidal Photonics, Inc Apparatus and methods relating to expanded dynamic range imaging endoscope systems
JP2007506485A (ja) * 2003-09-26 2007-03-22 タイダール フォトニクス,インク. カラー画像内視鏡システムに関する装置と方法
CA2581697A1 (en) * 2003-09-26 2005-04-07 Tidal Photonics, Inc. Apparatus and methods for performing phototherapy, photodynamic therapy and diagnosis
WO2005031292A1 (en) * 2003-09-26 2005-04-07 Tidal Photonics, Inc. Apparatus and methods relating to enhanced spectral measurement systems
WO2005047834A1 (en) * 2003-10-15 2005-05-26 Polychromix Corporation Light processor providing wavelength control and method for same
WO2005067389A2 (en) * 2004-01-15 2005-07-28 Technion Research & Development Foundation Ltd. Three-dimensional video scanner
WO2005121724A2 (en) * 2004-01-21 2005-12-22 Optical Insights, Llc Method and apparatus for multi-mode spectral imaging
US7342705B2 (en) 2004-02-03 2008-03-11 Idc, Llc Spatial light modulator with integrated optical compensation structure
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US7706050B2 (en) 2004-03-05 2010-04-27 Qualcomm Mems Technologies, Inc. Integrated modulator illumination
US7652765B1 (en) 2004-03-06 2010-01-26 Plain Sight Systems, Inc. Hyper-spectral imaging methods and devices
US7750886B2 (en) 2004-09-27 2010-07-06 Qualcomm Mems Technologies, Inc. Methods and devices for lighting displays
US20060072005A1 (en) * 2004-10-06 2006-04-06 Thomas-Wayne Patty J Method and apparatus for 3-D electron holographic visual and audio scene propagation in a video or cinematic arena, digitally processed, auto language tracking
KR100700913B1 (ko) * 2004-10-20 2007-03-28 고려대학교 산학협력단 공초점 라만 분광법을 이용한 조직으로부터의 자기-형광신호 감소 방법
WO2006055735A2 (en) * 2004-11-16 2006-05-26 Illumina, Inc Scanner having spatial light modulator
EP2194485B1 (de) 2004-11-16 2012-10-17 Illumina, Inc. Verfahren und Vorrichtung zum Auslesen kodierter Mikroperlen
US7604173B2 (en) 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
JP2006171024A (ja) * 2004-12-10 2006-06-29 Olympus Corp 多点蛍光分光測光顕微鏡および多点蛍光分光測光方法
WO2006080023A1 (en) * 2005-01-31 2006-08-03 Cognitens Ltd. Method and system for illumination adjustment
KR100721512B1 (ko) 2005-02-16 2007-05-23 한국과학기술원 분산 광학계를 이용한 실시간 공초점 현미경
JP2006235420A (ja) * 2005-02-28 2006-09-07 Yokogawa Electric Corp 共焦点顕微鏡
JP4538633B2 (ja) * 2005-03-29 2010-09-08 国立大学法人浜松医科大学 Dlp式スリット光走査顕微鏡
JP3755888B2 (ja) * 2005-06-14 2006-03-15 株式会社林創研 バイオチップオンライン分析システム
GB0514656D0 (en) 2005-07-16 2005-08-24 Cairn Res Ltd Control of illumination in microscopy
US7593156B2 (en) * 2005-08-26 2009-09-22 Leica Microsystems (Schweiz) Ag Microscope with micro-mirrors for optional deflection and/or beam splitting
DE102005040471B4 (de) * 2005-08-26 2007-06-21 Leica Microsystems (Schweiz) Ag Mikroskop
US7623624B2 (en) 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
JP4887989B2 (ja) * 2005-12-02 2012-02-29 ナノフォトン株式会社 光学顕微鏡及びスペクトル測定方法
US7460229B2 (en) * 2006-01-13 2008-12-02 Thermo Electron Scientific Instruments Llc Beam alignment in spectroscopic microscopes
US7916980B2 (en) 2006-01-13 2011-03-29 Qualcomm Mems Technologies, Inc. Interconnect structure for MEMS device
US7603001B2 (en) 2006-02-17 2009-10-13 Qualcomm Mems Technologies, Inc. Method and apparatus for providing back-lighting in an interferometric modulator display device
GB0606788D0 (en) * 2006-04-03 2006-05-10 Ind Co Ltd Confocal microscopy
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
DE102006022592B4 (de) * 2006-05-15 2008-02-07 Leica Microsystems (Schweiz) Ag Mikroskop mit Beleuchtungseinheit
US7766498B2 (en) 2006-06-21 2010-08-03 Qualcomm Mems Technologies, Inc. Linear solid state illuminator
US20080260242A1 (en) * 2006-06-22 2008-10-23 Tidal Photonics Inc. Apparatus and methods for measuring and controlling illumination for imaging objects, performances and the like
US7990524B2 (en) * 2006-06-30 2011-08-02 The University Of Chicago Stochastic scanning apparatus using multiphoton multifocal source
US7483135B2 (en) * 2006-07-14 2009-01-27 Thermo Electron Scientific Instruments, Llc Confocal spectrometer with astigmatic aperturing
US7652275B2 (en) * 2006-07-28 2010-01-26 Mitutoyo Corporation Non-contact probe control interface
US7845841B2 (en) 2006-08-28 2010-12-07 Qualcomm Mems Technologies, Inc. Angle sweeping holographic illuminator
ATE556272T1 (de) 2006-10-06 2012-05-15 Qualcomm Mems Technologies Inc Optische verluststruktur in einer beleuchtungsvorrichtung
US8107155B2 (en) * 2006-10-06 2012-01-31 Qualcomm Mems Technologies, Inc. System and method for reducing visual artifacts in displays
EP2069838A2 (de) 2006-10-06 2009-06-17 Qualcomm Mems Technologies, Inc. Beleuchtungsvorrichtung mit eingebautem lichtkoppler
US7855827B2 (en) 2006-10-06 2010-12-21 Qualcomm Mems Technologies, Inc. Internal optical isolation structure for integrated front or back lighting
US7623614B2 (en) * 2006-10-24 2009-11-24 Thermo Niton Analyzers Llc Apparatus for inspecting objects using coded beam
US7864395B2 (en) 2006-10-27 2011-01-04 Qualcomm Mems Technologies, Inc. Light guide including optical scattering elements and a method of manufacture
DE102007002583A1 (de) * 2006-11-03 2008-05-08 Leica Microsystems Cms Gmbh Optische Anordnung und Verfahren zum Steuern und Beeinflussen eines Lichtstrahls
US7777878B2 (en) * 2006-12-19 2010-08-17 J.A. Woollam Co., Inc. Application of digital light processor in scanning spectrometer and imaging ellipsometer and the like systems
US7777954B2 (en) 2007-01-30 2010-08-17 Qualcomm Mems Technologies, Inc. Systems and methods of providing a light guiding layer
US7692785B2 (en) * 2007-03-29 2010-04-06 General Electric Company System and method for optical power management
US7733439B2 (en) 2007-04-30 2010-06-08 Qualcomm Mems Technologies, Inc. Dual film light guide for illuminating displays
US7692841B2 (en) * 2007-07-31 2010-04-06 Texas Instruments Incorporated System and method for regulating micromirror position
WO2009102731A2 (en) 2008-02-12 2009-08-20 Qualcomm Mems Technologies, Inc. Devices and methods for enhancing brightness of displays using angle conversion layers
US8654061B2 (en) 2008-02-12 2014-02-18 Qualcomm Mems Technologies, Inc. Integrated front light solution
WO2009129264A1 (en) 2008-04-15 2009-10-22 Qualcomm Mems Technologies, Inc. Light with bi-directional propagation
US8118468B2 (en) * 2008-05-16 2012-02-21 Qualcomm Mems Technologies, Inc. Illumination apparatus and methods
US8305575B1 (en) * 2008-06-23 2012-11-06 Spectral Sciences, Inc. Adaptive spectral sensor and methods using same
CN101634747B (zh) * 2008-07-23 2012-01-11 中国科学院半导体研究所 高分辨率共聚焦显微镜
JP2010078559A (ja) * 2008-09-29 2010-04-08 Sumitomo Electric Ind Ltd 蛍光分析装置および方法
TWI396826B (zh) * 2008-12-31 2013-05-21 私立中原大學 Surface contour measuring device with auto focus and its measuring method
WO2010138761A1 (en) 2009-05-29 2010-12-02 Qualcomm Mems Technologies, Inc. Illumination devices and methods of fabrication thereof
WO2011136857A2 (en) * 2010-01-06 2011-11-03 Trustees Of Boston University Correlation confocal microscope
EP2369401B1 (de) * 2010-03-23 2015-09-23 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Optische Modulatorvorrichtung und räumlich-zeitlich lichtmoduliertes Bildgebungssystem
US8902484B2 (en) 2010-12-15 2014-12-02 Qualcomm Mems Technologies, Inc. Holographic brightness enhancement film
JP6121911B2 (ja) * 2011-01-20 2017-04-26 ジーイー・ヘルスケア・バイオサイエンス・コーポレイション 光走査システム
US9341515B2 (en) 2011-02-11 2016-05-17 University Of Central Florida Research Foundation, Inc. Optical absorbance measurement apparatus, method, and applications
JP6033798B2 (ja) * 2011-03-01 2016-11-30 ジーイー・ヘルスケア・バイオサイエンス・コーポレイション 蛍光顕微鏡検査法における照明位相制御のためのシステムおよび方法
US9110009B2 (en) * 2011-03-21 2015-08-18 University Of Central Florida Research Foundation, Inc. Gradient index (GRIN)-based absorption spectroscopy apparatus, method, and applications
DE102011083726A1 (de) 2011-09-29 2013-04-04 Siemens Aktiengesellschaft Konfokales Spektrometer und Verfahren zur Bildgebung in einem konfokalen Spektrometer
DE102011083718A1 (de) 2011-09-29 2013-04-04 Siemens Aktiengesellschaft Konfokales Spektrometer und Verfahren zur Bildgebung in einem konfokalen Spektrometer
KR20130094083A (ko) * 2012-02-15 2013-08-23 삼성전기주식회사 레이저 스캔 장치
DE102012203736A1 (de) * 2012-03-09 2013-09-12 Carl Zeiss Microscopy Gmbh Lichtrastermikroskop mit spektraler Detektion
US9200958B2 (en) * 2012-11-15 2015-12-01 Corning Incorporated Hyperspectral imaging systems and methods for imaging a remote object
JP5884021B2 (ja) * 2013-02-13 2016-03-15 パナソニックIpマネジメント株式会社 マルチスペクトル撮像装置およびマルチスペクトル撮像方法
JP6028633B2 (ja) * 2013-03-15 2016-11-16 株式会社Jvcケンウッド レーザ光源装置
US9927364B1 (en) * 2013-11-01 2018-03-27 The United States Of America, As Represented By The Secretary Of Agriculture Line-scan Raman imaging method and apparatus for sample evaluation
JP2015094851A (ja) * 2013-11-12 2015-05-18 株式会社リコー レンズユニット、画像読取装置および画像形成装置
JP6251073B2 (ja) * 2014-02-05 2017-12-20 浜松ホトニクス株式会社 分光器、及び分光器の製造方法
WO2015156782A1 (en) * 2014-04-08 2015-10-15 Pandata Research Llc Spectral detection for imaging system including a micromirror array
DE102014105222A1 (de) * 2014-04-11 2015-10-15 Jenoptik Optical Systems Gmbh Kamera mit integriertem Spektrometer
US9927371B2 (en) 2014-04-22 2018-03-27 Kla-Tencor Corporation Confocal line inspection optical system
DE112015001154T5 (de) * 2014-04-24 2016-12-08 Olympus Corporation Mikroskop und Mikroskopie-Verfahren
WO2016141339A1 (en) * 2015-03-04 2016-09-09 Aramco Services Company Adaptive optics for imaging through highly scattering media in oil reservoir applications
JPWO2017002535A1 (ja) * 2015-06-29 2018-05-31 国立大学法人徳島大学 計測装置
DE102015112769B4 (de) * 2015-08-04 2022-09-08 Carl Zeiss Ag Vorrichtung und Verfahren zur optischen Probenuntersuchung
JP6594437B2 (ja) 2015-09-15 2019-10-23 オリンパス株式会社 顕微鏡および顕微鏡観察方法
ITUB20154591A1 (it) * 2015-10-12 2017-04-12 Crestoptics S R L Apparato di microscopia confocale e relativo procedimento di acquisizione ed elaborazione di immagini
CN108700460B (zh) 2015-12-21 2020-11-03 威里利生命科学有限责任公司 成像系统和成像方法
EP3433654B1 (de) 2016-03-24 2020-09-30 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Räumlich-zeitlich lichtmoduliertes bildgebungssystem, verfahren zur konfokalen abbildung eines objekts und trägerradvorrichtung
JP2019514051A (ja) 2016-03-24 2019-05-30 マツクス−プランク−ゲゼルシヤフト ツール フエルデルング デル ヴイツセンシヤフテン エー フアウMAX−PLANCK−GESELLSCHAFT ZUR FOeRDERUNG DER WISSENSCHAFTEN E.V. 垂直方向のカメラを含む時空間光変調結像システム、および物体を共焦点結像させるための方法
US10627614B2 (en) 2016-04-11 2020-04-21 Verily Life Sciences Llc Systems and methods for simultaneous acquisition of multiple planes with one or more chromatic lenses
US10241337B2 (en) 2016-05-27 2019-03-26 Verily Life Sciences Llc Tunable spectral slicer and methods of use
US10539786B2 (en) 2016-05-27 2020-01-21 Verily Life Sciences Llc Rotatable prisms for controlling dispersion magnitude and orientation and methods of use
US10551604B2 (en) 2016-05-27 2020-02-04 Verily Life Sciences Llc Spatial light modulator based hyperspectral confocal microscopes and methods of use
EP3465157B1 (de) * 2016-05-27 2021-12-08 Verily Life Sciences LLC Systeme und verfahren zur 4-d hyperspektralen bildgebung
JP6810167B2 (ja) 2016-05-27 2021-01-06 ヴェリリー ライフ サイエンシズ エルエルシー 4dハイパースペクトル撮像のためのシステムおよび方法
JP7089719B2 (ja) * 2017-02-07 2022-06-23 ナノフォトン株式会社 分光顕微鏡、及び分光観察方法
CN107101982A (zh) * 2017-03-09 2017-08-29 深圳先进技术研究院 荧光显微装置
CN107084665B (zh) * 2017-05-02 2019-03-19 中北大学 一种光谱共焦位移传感器
FR3075401B1 (fr) 2017-12-14 2021-12-17 Alveole Microscopie 3d spectrale en champ large
EP3729161A1 (de) * 2017-12-20 2020-10-28 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und vorrichtung zur optischen konfokalen abbildung unter verwendung eines programmierbaren array-mikroskops
US11284786B2 (en) * 2019-03-07 2022-03-29 ZSquare Ltd. Spatial encoding system decoding system imaging system and methods thereof
KR102860250B1 (ko) 2019-03-28 2025-09-17 나노포톤 가부시키가이샤 이미지 데이터 취득 방법
JP2022527827A (ja) 2019-04-02 2022-06-06 サーモ エレクトロン サイエンティフィック インストルメンツ リミテッド ライアビリティ カンパニー 構造化照明顕微鏡法を使用した高度な試料画像化
EP4123290A4 (de) * 2020-04-24 2024-05-08 HORIBA, Ltd. Spektroskopische analysevorrichtung, spektroskopisches analyseverfahren und computerprogramm
JP2023125296A (ja) * 2022-02-28 2023-09-07 株式会社渋谷光学 分光エリプソメータ
DE102022206605A1 (de) * 2022-06-29 2024-01-04 Carl Zeiss Microscopy Gmbh Beleuchtungsvorrichtung und Mikroskopieverfahren zum Erzeugen eines zusammengesetzten Bildes einer Probe
GB2620627B (en) * 2022-07-14 2025-02-05 Andor Tech Limited Raman spectroscopy apparatus and method
CN115900590B (zh) * 2023-02-16 2023-06-13 武汉加特林光学仪器有限公司 一种高信噪比的光谱共焦三维检测系统及方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4856897A (en) * 1987-08-14 1989-08-15 D.O.M. Associates, Inc. Raman spectrometer having Hadamard electrooptical mask and diode detector
FR2626383B1 (fr) * 1988-01-27 1991-10-25 Commissariat Energie Atomique Procede de microscopie optique confocale a balayage et en profondeur de champ etendue et dispositifs pour la mise en oeuvre du procede
US5065008A (en) * 1989-10-18 1991-11-12 Fuji Photo Film Co., Ltd. Scanning microscope and scanning mechanism for the same
JPH03134608A (ja) * 1989-10-20 1991-06-07 Fuji Photo Film Co Ltd 走査型顕微鏡
US5121239A (en) * 1989-10-20 1992-06-09 The United States Of America As Represented By The Secretary Of The Air Force Filter having adjustable spectral transmittance function
JPH03150528A (ja) * 1989-11-08 1991-06-26 Fuji Photo Film Co Ltd 任意の分光分布を有する光の発生装置
US5090807A (en) * 1990-01-10 1992-02-25 Environmental Research Institute Of Michigan Real time optical pre-detection processing of multispectral image data
US5221959A (en) * 1990-03-16 1993-06-22 Olympus Optical Co., Ltd. Color discrimination data input apparatus
GB9014263D0 (en) * 1990-06-27 1990-08-15 Dixon Arthur E Apparatus and method for spatially- and spectrally- resolvedmeasurements
ATE137588T1 (de) * 1990-11-10 1996-05-15 Grosskopf Rudolf Dr Ing Optische abtastvorrichtung mit konfokalem strahlengang, in der lichtquellen- und detektormatrix verwendet werden
DE4111903A1 (de) * 1991-04-12 1992-10-15 Bayer Ag Spektroskopiekorrelierte licht-rastermikroskopie
CA2084923A1 (en) * 1991-12-20 1993-06-21 Ronald E. Stafford Slm spectrometer
JPH05210051A (ja) * 1992-01-30 1993-08-20 Yokogawa Electric Corp 共焦点用光スキャナ
US5587832A (en) * 1993-10-20 1996-12-24 Biophysica Technologies, Inc. Spatially light modulated confocal microscope and method
US5557315A (en) * 1994-08-18 1996-09-17 Eastman Kodak Company Digital printer using a modulated white light exposure source
JP3544019B2 (ja) * 1994-12-02 2004-07-21 株式会社キーエンス 光学顕微鏡及び光学顕微鏡の深度測定方法
DE19510102C1 (de) * 1995-03-20 1996-10-02 Rainer Dr Uhl Konfokales Fluoreszenzmikroskop
GB9603788D0 (en) * 1996-02-22 1996-04-24 Isis Innovation Confocal microscope
AU3649097A (en) * 1996-07-01 1998-01-21 Sony Electronics Inc. System for controlling the spectral distribution of light
DE69806496T2 (de) * 1997-10-29 2003-03-13 Macaulay, Calum E. Gerät und verfahren zur mikroskopie unter verwendung räumlich modulierten lichtes

Also Published As

Publication number Publication date
DE69730030D1 (de) 2004-09-02
JPH11249023A (ja) 1999-09-17
JP4712923B2 (ja) 2011-06-29
EP0916981A1 (de) 1999-05-19
DE69730030T2 (de) 2005-07-21
EP0916981B1 (de) 2004-07-28
US6128077A (en) 2000-10-03

Similar Documents

Publication Publication Date Title
DE69730030D1 (de) Konfokales Spektroskopiesystem und -verfahren
JP4376974B2 (ja) 媒体の局所的照明のための照明ユニット及び方法
US8376566B2 (en) Method and apparatus for object viewing, observation, inspection, identification, and verification
CA1319531C (en) Remote spectrophotometer
US7688447B2 (en) Color sensor
DE69812421T2 (de) Untersuchung von diamanten und edelsteinen
US20090040516A1 (en) Spectroscopic system
CA2277095A1 (en) Spatially resolved optical measurements
DE69021786D1 (de) Optisches System zur Spektralanalyse.
US7224446B2 (en) Apparatus, method, and computer program for wafer inspection
ES2151064T3 (es) Aparato para efectuar analisis espectrales de una fuente optica luminosa, utilizando deteccion de imagenes y separacion de ordenes espectrales especiales.
ATE360801T1 (de) Eichverfahren
EP1288651A3 (de) Verfahren und Vorrichtung zur Ermittlung von optischen Fehlern
DE69924358D1 (de) Laserlichtquelle mit diffraktiver optischer strahlintegration
US6208413B1 (en) Hadamard spectrometer
ATE245826T1 (de) Farbmessvorrichtung für einen anzeigeschirm
EP1736096A3 (de) Flimmerphotometer
KR960035166A (ko) 조명장치
EP1542459A3 (de) Optisches Beleuchtungssystem und Bildprojektor unter Verwendung desselben
EP1221598A4 (de) Optische ausgabevorrichtung mit variablen wellenlängen
US5742422A (en) Adjustable fourier mask
JPH1021722A (ja) 照明装置
JPS56119822A (en) Multichannel spectral radiometer
EP0372495A3 (de) Lichtgenerator mit variabler Helligkeit
KR100456203B1 (ko) 자동 광량조절장치 및 이것을 구비한 시편의 문자인식장치

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties