ATE272393T1 - Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen - Google Patents

Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen

Info

Publication number
ATE272393T1
ATE272393T1 AT00980600T AT00980600T ATE272393T1 AT E272393 T1 ATE272393 T1 AT E272393T1 AT 00980600 T AT00980600 T AT 00980600T AT 00980600 T AT00980600 T AT 00980600T AT E272393 T1 ATE272393 T1 AT E272393T1
Authority
AT
Austria
Prior art keywords
liposomes
solution
providing
mixture
membrane proteins
Prior art date
Application number
AT00980600T
Other languages
English (en)
Inventor
Pratap Singh
Original Assignee
Dade Behring Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Inc filed Critical Dade Behring Inc
Application granted granted Critical
Publication of ATE272393T1 publication Critical patent/ATE272393T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT00980600T 1999-12-10 2000-11-20 Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen ATE272393T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/459,137 US6248353B1 (en) 1999-12-10 1999-12-10 Reconstitution of purified membrane proteins into preformed liposomes
PCT/US2000/031927 WO2001041740A2 (en) 1999-12-10 2000-11-20 Reconstitution of purified membrane proteins into preformed liposomes

Publications (1)

Publication Number Publication Date
ATE272393T1 true ATE272393T1 (de) 2004-08-15

Family

ID=23823557

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00980600T ATE272393T1 (de) 1999-12-10 2000-11-20 Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen

Country Status (7)

Country Link
US (2) US6248353B1 (de)
EP (1) EP1239833B1 (de)
JP (1) JP4612261B2 (de)
AT (1) ATE272393T1 (de)
DE (1) DE60012785T2 (de)
ES (1) ES2225271T3 (de)
WO (1) WO2001041740A2 (de)

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US6248353B1 (en) * 1999-12-10 2001-06-19 Dade Behring Inc. Reconstitution of purified membrane proteins into preformed liposomes
US7622437B2 (en) * 2000-11-20 2009-11-24 The Board Of Trustees Of The University Of Illinois Tissue factor compositions and methods
WO2002040501A2 (en) * 2000-11-20 2002-05-23 The Board Of Trustees Of The University Of Illinois Membrane scaffold proteins
US7592008B2 (en) * 2000-11-20 2009-09-22 The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois Membrane scaffold proteins
US7083958B2 (en) * 2000-11-20 2006-08-01 The Board Of Trustees Of The University Of Illinois Membrane scaffold proteins
US6596543B2 (en) * 2001-03-22 2003-07-22 Dade Behring Inc. Use of liposomes of defined composition and size for the preparation of prothrombin time reagents
US7015193B2 (en) * 2001-04-20 2006-03-21 University Of Vermont Compositions and methods to control bleeding
WO2003075889A1 (en) * 2002-03-05 2003-09-18 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections
US20040105881A1 (en) * 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
US20050032113A1 (en) * 2003-07-17 2005-02-10 Mitsubishi Pharma Corporation Membrane protein library for proteome analysis and method for preparing same
KR101076578B1 (ko) 2004-06-23 2011-10-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 2입자 착물을 이용한 생물학적 분자의 검출을 위한 방법 및조성물
US7148067B2 (en) * 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
EP1811961A2 (de) * 2004-11-12 2007-08-01 Idea Ag Erweiterte oberflächen-aggregate bei der behandlung von hauterkrankungen
US20080260858A1 (en) * 2005-02-16 2008-10-23 The Board Of Trustees Of The University Of Illnois Universal Procoagulant
AT501650A1 (de) * 2005-02-22 2006-10-15 Technoclone Ges M B H Verfahren zur bestimmung der gerinnungsaktivierung sowie gerät zur durchführung des verfahrens
WO2006096345A2 (en) * 2005-03-04 2006-09-14 The Board Of Trustees Of The University Of Illinois Coagulation and fibrinolytic cascades modulator
US20080248565A1 (en) * 2007-03-01 2008-10-09 Invitrogen Corporation Isolated phospholipid-protein particles
US20070117179A1 (en) * 2005-09-27 2007-05-24 Invitrogen Corporation In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles
JP2007106679A (ja) * 2005-10-11 2007-04-26 Shino Test Corp 血液凝固反応促進剤
EP1939218A1 (de) * 2006-12-29 2008-07-02 Thrombotargets Europe, S.L. Mikrovesikel aus rekombinanter Hefe mit blutstillender Wirkung und Verwendung dafür
EP2120876B1 (de) 2007-03-05 2015-03-04 Washington University Nanopartikel-freisetzungssysteme für membranintegrierende peptide
JP5731198B2 (ja) 2007-09-27 2015-06-10 イムノバクシーン・テクノロジーズ・インコーポレイテッドＩｍｍｕｎｏｖａｃｃｉｎｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． インビボでのポリヌクレオチドの送達のための連続疎水相を含む担体におけるリポソームの使用
EP2062661A1 (de) * 2007-09-28 2009-05-27 Proviron Holding Entfernung eines organischen Enteisers
US20100209452A1 (en) * 2007-10-03 2010-08-19 Immunovaccine Technologies, Inc Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof
WO2009046194A2 (en) * 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
US20100297257A1 (en) 2007-11-09 2010-11-25 National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs) Anticoagulant antagonist and hemophillia procoagulant
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US8956600B2 (en) 2009-08-10 2015-02-17 Taiwan Liposome Co. Ltd. Ophthalmic drug delivery system containing phospholipid and cholesterol
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US10894098B2 (en) 2012-04-09 2021-01-19 Signablok, Inc. Methods and compositions for targeted imaging
US10525152B2 (en) 2009-10-09 2020-01-07 Signablok, Inc. Methods and compositions for targeted imaging
KR101458315B1 (ko) 2013-07-19 2014-11-04 전북대학교산학협력단 표면 개질된 리포좀 및 그 제조방법
JP6652873B2 (ja) * 2016-03-30 2020-02-26 シスメックス株式会社 プロトロンビン時間測定用試薬、その製造方法およびプロトロンビン時間の測定方法
JP6626761B2 (ja) * 2016-03-30 2019-12-25 シスメックス株式会社 プロトロンビン時間測定用試薬およびその製造方法
WO2019200240A1 (en) 2018-04-13 2019-10-17 Board Of Regents, The University Of Texas System Transmembrane stem cell factor (tm-scf) lipid nanocarriers and methods of use thereof
KR102704912B1 (ko) * 2018-07-06 2024-09-06 피에이치씨 주식회사 리포좀을 함유하는 액상 혈액응고능력 측정시약
JP7153519B2 (ja) * 2018-09-28 2022-10-14 シスメックス株式会社 凝固時間測定用試薬及びその製造方法、試薬キット及び凝固時間の測定方法

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Also Published As

Publication number Publication date
WO2001041740A2 (en) 2001-06-14
US6706861B2 (en) 2004-03-16
US6248353B1 (en) 2001-06-19
US20020012699A1 (en) 2002-01-31
JP4612261B2 (ja) 2011-01-12
EP1239833A2 (de) 2002-09-18
ES2225271T3 (es) 2005-03-16
DE60012785T2 (de) 2005-08-11
DE60012785D1 (de) 2004-09-09
JP2003516525A (ja) 2003-05-13
WO2001041740A3 (en) 2002-01-17
EP1239833B1 (de) 2004-08-04

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