ATE272404T1 - Verwendung von taurolidine zur herstellung eines arzneimittels zur behandlung von leukämien - Google Patents
Verwendung von taurolidine zur herstellung eines arzneimittels zur behandlung von leukämienInfo
- Publication number
- ATE272404T1 ATE272404T1 AT98923672T AT98923672T ATE272404T1 AT E272404 T1 ATE272404 T1 AT E272404T1 AT 98923672 T AT98923672 T AT 98923672T AT 98923672 T AT98923672 T AT 98923672T AT E272404 T1 ATE272404 T1 AT E272404T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- taurolidine
- leukemia
- production
- medicinal product
- Prior art date
Links
- 208000032839 leukemia Diseases 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- AJKIRUJIDFJUKJ-UHFFFAOYSA-N taurolidine Chemical compound C1NS(=O)(=O)CCN1CN1CNS(=O)(=O)CC1 AJKIRUJIDFJUKJ-UHFFFAOYSA-N 0.000 title 1
- 229960004267 taurolidine Drugs 0.000 title 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4764297P | 1997-05-22 | 1997-05-22 | |
| PCT/US1998/010494 WO1998052572A1 (en) | 1997-05-22 | 1998-05-22 | Use of taurolidine for treatment of leukemias |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE272404T1 true ATE272404T1 (de) | 2004-08-15 |
Family
ID=21950114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98923672T ATE272404T1 (de) | 1997-05-22 | 1998-05-22 | Verwendung von taurolidine zur herstellung eines arzneimittels zur behandlung von leukämien |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6303596B1 (de) |
| EP (1) | EP0983069B1 (de) |
| AT (1) | ATE272404T1 (de) |
| AU (1) | AU734460B2 (de) |
| CA (1) | CA2290537C (de) |
| DE (1) | DE69825440T2 (de) |
| WO (1) | WO1998052572A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6749853B1 (en) * | 1992-03-05 | 2004-06-15 | Board Of Regents, The University Of Texas System | Combined methods and compositions for coagulation and tumor treatment |
| WO1998031394A2 (en) | 1997-01-22 | 1998-07-23 | Board Of Regents, The University Of Texas System | Tissue factor methods and compositions for coagulation and tumor treatment |
| US20050124608A1 (en) * | 2001-04-03 | 2005-06-09 | Redmond H. P. | Treatment of cancers |
| US20070275955A1 (en) * | 1997-07-31 | 2007-11-29 | Ed. Geistlich Soehne Ag | Method of treating tumors |
| US8304390B2 (en) * | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US20030027818A1 (en) * | 2001-04-03 | 2003-02-06 | Redmond H. Paul | Treatment of cancers |
| US7345039B2 (en) * | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US7892530B2 (en) | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| EP1248625A2 (de) * | 1999-12-06 | 2002-10-16 | Rhode Island Hospital | Verwendung von methylol-enthaltenden verbindungen zur herstellung eines medikaments zur behandlung von tumoren |
| EP1797884B1 (de) * | 1999-12-06 | 2013-09-11 | Geistlich Pharma AG | Taurolidin oder Taurultam zur Verwendung bei der Behandlung von Tumoren der Prostata, des Kolons, der Lungen und von wiederkehrendem Glioblastoma multiforme. |
| CN100519525C (zh) | 1999-12-06 | 2009-07-29 | 葛兰素集团有限公司 | 芳香砜类及其医疗用途 |
| EP1450814B1 (de) | 2001-10-01 | 2016-11-30 | Geistlich Pharma AG | Verfahren zur hemmung von metastasen |
| CA2482687C (en) | 2003-09-29 | 2012-11-20 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of mesothelioma |
| WO2005115357A2 (en) * | 2004-05-14 | 2005-12-08 | Hans-Dietrich Polaschegg | Taurolidine formulations and delivery |
| US20100040667A1 (en) * | 2006-09-07 | 2010-02-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treating bone cancer |
| CN111635888A (zh) * | 2020-04-21 | 2020-09-08 | 西南医科大学附属医院 | 双黄连用于诱导人急性t淋巴细胞白血病细胞凋亡的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9005856D0 (en) | 1990-03-15 | 1990-05-09 | Geistlich Soehne Ag | Compositions |
-
1998
- 1998-05-22 AU AU75906/98A patent/AU734460B2/en not_active Ceased
- 1998-05-22 CA CA002290537A patent/CA2290537C/en not_active Expired - Fee Related
- 1998-05-22 EP EP98923672A patent/EP0983069B1/de not_active Expired - Lifetime
- 1998-05-22 WO PCT/US1998/010494 patent/WO1998052572A1/en not_active Ceased
- 1998-05-22 DE DE69825440T patent/DE69825440T2/de not_active Expired - Fee Related
- 1998-05-22 US US09/424,426 patent/US6303596B1/en not_active Expired - Lifetime
- 1998-05-22 AT AT98923672T patent/ATE272404T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6303596B1 (en) | 2001-10-16 |
| CA2290537C (en) | 2007-10-02 |
| DE69825440D1 (de) | 2004-09-09 |
| CA2290537A1 (en) | 1998-11-26 |
| EP0983069B1 (de) | 2004-08-04 |
| WO1998052572A1 (en) | 1998-11-26 |
| EP0983069A1 (de) | 2000-03-08 |
| AU734460B2 (en) | 2001-06-14 |
| DE69825440T2 (de) | 2005-07-28 |
| AU7590698A (en) | 1998-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |