ATE273023T1 - Verfahren und zusammensetzung zur konservierung von antigenen und verfahren zur verwendung von durch selbiges verfahren hergestellten zytologischem material - Google Patents
Verfahren und zusammensetzung zur konservierung von antigenen und verfahren zur verwendung von durch selbiges verfahren hergestellten zytologischem materialInfo
- Publication number
- ATE273023T1 ATE273023T1 AT93922165T AT93922165T ATE273023T1 AT E273023 T1 ATE273023 T1 AT E273023T1 AT 93922165 T AT93922165 T AT 93922165T AT 93922165 T AT93922165 T AT 93922165T AT E273023 T1 ATE273023 T1 AT E273023T1
- Authority
- AT
- Austria
- Prior art keywords
- cell
- composition
- antigens
- preserving
- material produced
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 230000002380 cytological effect Effects 0.000 title 1
- 239000000463 material Substances 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 230000000890 antigenic effect Effects 0.000 abstract 2
- 239000000834 fixative Substances 0.000 abstract 2
- 230000004075 alteration Effects 0.000 abstract 1
- 210000003850 cellular structure Anatomy 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000001024 immunotherapeutic effect Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000013641 positive control Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94335992A | 1992-09-10 | 1992-09-10 | |
| PCT/US1993/008520 WO1994007532A1 (en) | 1992-09-10 | 1993-09-09 | Method and composition for preserving antigens and process for utilizing cytological material produced by same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE273023T1 true ATE273023T1 (de) | 2004-08-15 |
Family
ID=25479519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93922165T ATE273023T1 (de) | 1992-09-10 | 1993-09-09 | Verfahren und zusammensetzung zur konservierung von antigenen und verfahren zur verwendung von durch selbiges verfahren hergestellten zytologischem material |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0639985B1 (de) |
| AT (1) | ATE273023T1 (de) |
| CA (1) | CA2123227C (de) |
| DE (1) | DE69333586T2 (de) |
| WO (1) | WO1994007532A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2197168T3 (es) | 1993-07-05 | 2004-01-01 | Sheffield Teaching Hospitals National Health Service Trust | Preparacion y estabilizacion de celulas. |
| CN1149338A (zh) * | 1994-04-05 | 1997-05-07 | 北方总医院N·H·S·托拉斯 | 细胞悬浮液的制备和稳定化 |
| EP0900367A1 (de) | 1996-04-12 | 1999-03-10 | Oncor, Inc. | Verfahren und zusammensetzung zur kontrolle der fixierung formaldehyd durch verzögerte abschrecken |
| US6072086A (en) * | 1996-04-12 | 2000-06-06 | Intergen Company | Method and composition for controlling formaldehyde fixation by delayed quenching |
| US5980904A (en) * | 1998-11-18 | 1999-11-09 | Amway Corporation | Skin whitening composition containing bearberry extract and a reducing agent |
| DE102005013261A1 (de) * | 2005-03-22 | 2006-09-28 | Adnagen Ag | Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen |
| FR2928518B1 (fr) * | 2008-03-13 | 2012-12-21 | Ogf | Nouvelle composition pour la conservation des tissus |
| FR2948456B1 (fr) | 2009-07-22 | 2011-09-30 | Reactifs Ral | Composition de fixation cytologique ou histologique et procedes de coloration |
| EP2618658A2 (de) | 2010-09-21 | 2013-07-31 | Herz- und Diabeteszentrum Nordrhein-Westfalen Krankenhausbetriebsgesellschaft Bad Oeynhausen mbH | Stabilisierte leukozyten und ihre verwendung für die diagnose und therapie von hiv |
| DE102012101896A1 (de) * | 2012-03-06 | 2013-09-12 | Roberto Gerigk | Formalinfreie Fixierungsmittel für histologische Färbungen von Gewebeproben |
| US9733162B2 (en) | 2014-02-11 | 2017-08-15 | Ihor Turkevych | Universal system, method and solution for the acceleration of the process of fixing, dehydrating and clearing the structure of biological tissue |
| US9771571B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| DE102015017080B3 (de) | 2014-02-28 | 2024-01-04 | Gen-Probe Incorporated | Verfahren zur Isolierung von Nukleinsäure von zytologischen Proben in flüssigen Konservierungsmitteln, die Formaldehyd enthalten |
| US9771572B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| CN111484992B (zh) | 2014-02-28 | 2024-04-02 | 简·探针公司 | 从含有甲醛的液基细胞学防腐剂中的样本分离核酸的方法 |
| US11313772B2 (en) | 2015-11-13 | 2022-04-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Fixatives and methods of use |
| CN111380735B (zh) * | 2018-12-28 | 2022-08-23 | 哈尔滨格林标本技术开发有限公司 | 一种高效环保生物组织处理液及其处理组织切片方法 |
| IT201900000661A1 (it) * | 2019-01-16 | 2020-07-16 | Kaltek S R L | Soluzione per la conservazione di campioni biologici ed uso di tale soluzione |
| WO2025262495A1 (en) * | 2024-06-19 | 2025-12-26 | Addax Biosciences Srl | Compositions for processing histological and cytological preparations comprising reagents and antioxidant agents that counteract the effect of molecular damage and dna and rna fragmentation |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL73904C (de) * | 1950-01-07 | 1900-01-01 | ||
| US4287087A (en) * | 1977-02-25 | 1981-09-01 | Research Triangle Institute | Fixed-dried blood platelets |
| US4404181A (en) * | 1981-10-15 | 1983-09-13 | Cambridge Chemical Products, Inc. | Extended-life tissue fixative composition and method of using the same |
| US4493821A (en) * | 1982-02-04 | 1985-01-15 | Harrison James S | Preservative and fixative preparations for biological systems |
| EP0118634A1 (de) * | 1983-03-15 | 1984-09-19 | Robert Stephen Davidson | Fixationslösung |
| US4666699A (en) * | 1985-03-04 | 1987-05-19 | Allegheny-Singer Research Institute | Stain-fixative composition for enteric parasites |
| US4882284A (en) * | 1987-04-13 | 1989-11-21 | Ortho Pharmaceutical Corporation | Method for quantitating and differentiating white blood cells |
| US4946669A (en) * | 1987-10-09 | 1990-08-07 | Siegfried Barry A | Histological fixatives |
| US4844891A (en) * | 1988-02-03 | 1989-07-04 | Lonza, Inc. | Admixtures of iodopropargyl compounds and a formaldehyde donor |
| DE3831242A1 (de) * | 1988-09-14 | 1990-03-22 | Basf Lacke & Farben | Kondensationsprodukte auf basis von kolophonium |
| EP0433516A1 (de) * | 1989-12-20 | 1991-06-26 | William A. Lemberger | Konservierungsmittel für biologische präparate |
| US5250438A (en) * | 1990-05-09 | 1993-10-05 | Streck Laboratories, Inc. | Method for differential determination of white blood cells using diazolidinyl urea to stabilize white blood cells |
| US5260048A (en) * | 1991-05-08 | 1993-11-09 | Streck Laboratories, Inc. | Tissue fixative solution and method |
-
1993
- 1993-09-09 EP EP93922165A patent/EP0639985B1/de not_active Expired - Lifetime
- 1993-09-09 DE DE69333586T patent/DE69333586T2/de not_active Expired - Lifetime
- 1993-09-09 AT AT93922165T patent/ATE273023T1/de not_active IP Right Cessation
- 1993-09-09 CA CA002123227A patent/CA2123227C/en not_active Expired - Lifetime
- 1993-09-09 WO PCT/US1993/008520 patent/WO1994007532A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2123227C (en) | 2009-04-28 |
| EP0639985A4 (de) | 1996-02-28 |
| CA2123227A1 (en) | 1994-04-14 |
| EP0639985A1 (de) | 1995-03-01 |
| EP0639985B1 (de) | 2004-08-11 |
| DE69333586T2 (de) | 2005-09-01 |
| DE69333586D1 (de) | 2004-09-16 |
| WO1994007532A1 (en) | 1994-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |