ATE273386T1 - Menschliches cyclin e - Google Patents

Menschliches cyclin e

Info

Publication number
ATE273386T1
ATE273386T1 AT92920511T AT92920511T ATE273386T1 AT E273386 T1 ATE273386 T1 AT E273386T1 AT 92920511 T AT92920511 T AT 92920511T AT 92920511 T AT92920511 T AT 92920511T AT E273386 T1 ATE273386 T1 AT E273386T1
Authority
AT
Austria
Prior art keywords
human cyclin
cyclin
polypeptide
determining
methods
Prior art date
Application number
AT92920511T
Other languages
English (en)
Inventor
James M Roberts
Motoaki Ohtsubo
Andrew C Koff
Frederick Cross
Original Assignee
Hutchinson Fred Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hutchinson Fred Cancer Res filed Critical Hutchinson Fred Cancer Res
Application granted granted Critical
Publication of ATE273386T1 publication Critical patent/ATE273386T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT92920511T 1991-09-20 1992-09-16 Menschliches cyclin e ATE273386T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76430991A 1991-09-20 1991-09-20
PCT/US1992/007866 WO1993006123A1 (en) 1991-09-20 1992-09-16 Human cyclin e

Publications (1)

Publication Number Publication Date
ATE273386T1 true ATE273386T1 (de) 2004-08-15

Family

ID=25070333

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92920511T ATE273386T1 (de) 1991-09-20 1992-09-16 Menschliches cyclin e

Country Status (7)

Country Link
US (5) US5449755A (de)
EP (1) EP0604560B1 (de)
JP (2) JPH07502164A (de)
AT (1) ATE273386T1 (de)
CA (1) CA2119443C (de)
DE (1) DE69233399T2 (de)
WO (1) WO1993006123A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07502164A (ja) * 1991-09-20 1995-03-09 フレッド ハッチンソン キャンサー リサーチ センター ヒトサイクリンｅ
US6372249B1 (en) * 1991-12-16 2002-04-16 Baylor College Of Medicine Senscent cell-derived inhibitors of DNA synthesis
US5596079A (en) * 1991-12-16 1997-01-21 Smith; James R. Mimetics of senescent cell derived inhibitors of DNA synthesis
US5484727A (en) * 1992-10-14 1996-01-16 Trustees Of Dartmouth College Cloned gene encoding acylcoenzyme A: cholesterol acyltransferase (ACAT)
US5543291A (en) * 1993-01-29 1996-08-06 Dana Farber Cancer Institute Method of detecting carcinoma
US5443962A (en) * 1993-06-04 1995-08-22 Mitotix, Inc. Methods of identifying inhibitors of cdc25 phosphatase
US5625031A (en) * 1994-02-08 1997-04-29 Bristol-Myers Squibb Company Peptide inhibitors of the p33cdk2 and p34cdc2 cell cycle regulatory kinases and human papillomavirus E7 oncoprotein
DE19539130C2 (de) * 1995-02-28 1999-05-12 Max Planck Gesellschaft Mittel zur Therapie von Tumoren und anderen Hyperplasien
US5763219A (en) 1995-09-07 1998-06-09 Health Research, Incorporated Cyclin E variants and use thereof
US20030086927A1 (en) * 1995-11-01 2003-05-08 University Of Southern California Expression of cyclin G1 in tumors
GB9613418D0 (en) * 1996-06-26 1996-08-28 Crc Technology Ltd A cell-free system for initiation of DNA replication
AU3651997A (en) * 1996-07-24 1998-02-10 Pharmacia & Upjohn Company Constructs and complexes of cyclin e
US6274312B1 (en) 1996-12-11 2001-08-14 Schering Corporation Intracellular regulatory molecules; related reagents
EP0983510B1 (de) * 1997-05-20 2004-03-03 Erasmus Universiteit Rotterdam Erkennung von tmorspezifische genprodukte
US5843721A (en) * 1997-07-03 1998-12-01 Tularik Inc. Nucleic acids encoding human NIK protein
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
PL342447A1 (en) * 1997-10-27 2001-06-04 Agouron Pharma Substituted 4-amino thiazol-2-yl compounds as inhibitors of cyclin-dependent kinases
US5973119A (en) 1998-06-05 1999-10-26 Amgen Inc. Cyclin E genes and proteins
US6492398B1 (en) 1999-03-04 2002-12-10 Smithkline Beechman Corporation Thiazoloindolinone compounds
US6624171B1 (en) 1999-03-04 2003-09-23 Smithkline Beecham Corporation Substituted aza-oxindole derivatives
GB9904933D0 (en) * 1999-03-04 1999-04-28 Glaxo Group Ltd Compounds
WO2001000821A1 (en) * 1999-06-23 2001-01-04 Angiogene Inc. Antisense oligonucleotide modulating cyclin e gene expression and therapeutic uses thereof
AU1366901A (en) * 1999-09-23 2001-04-24 Rigel Pharmaceuticals, Inc. Traf4 associated cell cycle proteins, compositions and methods of use
US6864355B1 (en) 2000-05-02 2005-03-08 Yale University Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain
US6887675B1 (en) 1999-10-25 2005-05-03 Rigel Pharmaceuticals, Inc. Tankyrase H, compositions involved in the cell cycle and methods of use
US6589725B1 (en) * 1999-10-25 2003-07-08 Rigel Pharmaceuticals, Inc. Tankyrase H, compositions involved in the cell cycle and methods of use
US20030236300A1 (en) * 1999-10-27 2003-12-25 Yale University Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
US20030149113A1 (en) * 2001-10-12 2003-08-07 Caplan Michael J. Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
HK1051543A1 (zh) 2000-01-12 2003-08-08 Yale University Nogo受体介导的轴突生长封锁
WO2001059448A1 (fr) * 2000-02-10 2001-08-16 Chugai Seiyaku Kabushiki Kaisha Procede de criblage d'un agent antiandrogene
US6620818B1 (en) 2000-03-01 2003-09-16 Smithkline Beecham Corporation Method for reducing the severity of side effects of chemotherapy and/or radiation therapy
CN1322733A (zh) * 2000-05-09 2001-11-21 上海博德基因开发有限公司 一种新的多肽——人npat蛋白11和编码这种多肽的多核苷酸
CA2532036A1 (en) * 2003-07-11 2005-02-03 Merck & Co., Inc. Methods for identifying cell surface receptor protein modulators
DE602004024831D1 (de) 2004-04-22 2010-02-04 Ortho Mcneil Pharm Inc Hdm2-inhibitorkomplexe und verwendungen davon
US8703769B2 (en) * 2005-07-15 2014-04-22 The University Of North Carolina At Chapel Hill Use of EGFR inhibitors to prevent or treat obesity
US20170117214A1 (en) 2009-01-05 2017-04-27 Amkor Technology, Inc. Semiconductor device with through-mold via
US12019081B2 (en) 2020-11-06 2024-06-25 University Of Kentucky Research Foundation Method for detection and quantification of CLN3 protein
CN116217722B (zh) * 2023-03-22 2023-09-15 广东省第二人民医院（广东省卫生应急医院） 一种抗CyclinE蛋白的纳米抗体及编码基因和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658204A1 (fr) * 1990-02-12 1991-08-16 Inst Nat Sante Rech Med Nouvelles compositions de cycline a humaine, sequence nucleotidique correspondante, et agents de detection ou de diagnostic de mutations hepatocellulaires induites par le virus hbv.
JPH07502164A (ja) * 1991-09-20 1995-03-09 フレッド ハッチンソン キャンサー リサーチ センター ヒトサイクリンｅ
US5543291A (en) * 1993-01-29 1996-08-06 Dana Farber Cancer Institute Method of detecting carcinoma

Also Published As

Publication number Publication date
US5783661A (en) 1998-07-21
CA2119443C (en) 1999-11-02
DE69233399D1 (de) 2004-09-16
WO1993006123A1 (en) 1993-04-01
US5807698A (en) 1998-09-15
CA2119443A1 (en) 1993-04-01
EP0604560A1 (de) 1994-07-06
US5449755A (en) 1995-09-12
EP0604560B1 (de) 2004-08-11
AU2666392A (en) 1993-04-27
US5861259A (en) 1999-01-19
JP2004222728A (ja) 2004-08-12
EP0604560A4 (de) 1995-05-24
JPH07502164A (ja) 1995-03-09
AU676137B2 (en) 1997-03-06
DE69233399T2 (de) 2005-08-04
US5645999A (en) 1997-07-08

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