ATE274517T1 - Verfahren und hydantoin zwischenprodukte für die synthese von wachtumshormonsekretionsförderern - Google Patents

Verfahren und hydantoin zwischenprodukte für die synthese von wachtumshormonsekretionsförderern

Info

Publication number
ATE274517T1
ATE274517T1 AT99309203T AT99309203T ATE274517T1 AT E274517 T1 ATE274517 T1 AT E274517T1 AT 99309203 T AT99309203 T AT 99309203T AT 99309203 T AT99309203 T AT 99309203T AT E274517 T1 ATE274517 T1 AT E274517T1
Authority
AT
Austria
Prior art keywords
synthesis
growth hormone
intermediate products
hormone secretion
secretion promoters
Prior art date
Application number
AT99309203T
Other languages
English (en)
Inventor
Charles Kwok-Fung Chiu
David Andrew Griffith
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE274517T1 publication Critical patent/ATE274517T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D247/00—Heterocyclic compounds containing rings having two nitrogen atoms as the only ring hetero atoms, according to more than one of groups C07D229/00 - C07D245/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT99309203T 1998-11-23 1999-11-18 Verfahren und hydantoin zwischenprodukte für die synthese von wachtumshormonsekretionsförderern ATE274517T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10952498P 1998-11-23 1998-11-23

Publications (1)

Publication Number Publication Date
ATE274517T1 true ATE274517T1 (de) 2004-09-15

Family

ID=22328134

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99309203T ATE274517T1 (de) 1998-11-23 1999-11-18 Verfahren und hydantoin zwischenprodukte für die synthese von wachtumshormonsekretionsförderern

Country Status (20)

Country Link
US (4) US6297380B1 (de)
EP (1) EP1004583B1 (de)
JP (2) JP3488155B2 (de)
KR (1) KR20000035568A (de)
CN (1) CN1255498A (de)
AR (1) AR019498A1 (de)
AT (1) ATE274517T1 (de)
AU (1) AU5958499A (de)
BR (1) BR9905732A (de)
CA (1) CA2290252C (de)
DE (1) DE69919663T2 (de)
DK (1) DK1004583T3 (de)
ES (1) ES2226297T3 (de)
HU (1) HUP9904384A3 (de)
ID (1) ID23852A (de)
IL (1) IL133043A0 (de)
PL (1) PL336710A1 (de)
PT (1) PT1004583E (de)
TR (1) TR199902879A2 (de)
ZA (1) ZA997227B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058947A1 (en) * 1997-06-25 1998-12-30 Pfizer Inc. Dipeptide derivatives as growth hormone secretagogues
US6297380B1 (en) 1998-11-23 2001-10-02 Pfizer Inc. Process and intermediates for growth hormone secretagogues
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (de) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Kondensierte heterozyklische Succinimid-Verbindungen und Analoga daraus, Modulatoren der nuklearen Hormonrezeptorfunktion
US6710064B2 (en) 2000-12-01 2004-03-23 Bristol-Myers Squibb Co. Hydantoin compounds useful as anti-inflammatory agents
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
WO2003011824A1 (en) 2001-07-31 2003-02-13 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
US7087636B2 (en) * 2001-12-19 2006-08-08 Bristol-Myers Squibb Company Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function
US7405234B2 (en) 2002-05-17 2008-07-29 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
WO2004045518A2 (en) 2002-11-15 2004-06-03 Bristol-Myers Squibb Company Open chain prolyl urea-related modulators of androgen receptor function
US7820702B2 (en) 2004-02-04 2010-10-26 Bristol-Myers Squibb Company Sulfonylpyrrolidine modulators of androgen receptor function and method
US7625923B2 (en) 2004-03-04 2009-12-01 Bristol-Myers Squibb Company Bicyclic modulators of androgen receptor function
US7696241B2 (en) 2004-03-04 2010-04-13 Bristol-Myers Squibb Company Bicyclic compounds as modulators of androgen receptor function and method
ES2690205T3 (es) * 2006-04-13 2018-11-19 Neurotech Pharmaceuticals Co., Ltd. Composición farmacéutica para tratar o prevenir enfermedades inflamatorias
EP2039695A4 (de) * 2006-07-11 2010-09-15 Takeda Pharmaceutical Bicyclische heterocylische verbindung und deren verwendung
IL300309B2 (en) * 2020-08-12 2026-03-01 Genentech Inc Synthesis of quinazoline compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4746755A (en) 1986-05-06 1988-05-24 The Dow Chemical Company Preparation of hydrantoic acids and hydantoins
DE3643748A1 (de) 1986-12-20 1988-06-30 Hoechst Ag Bicylische imide, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz
US4868061A (en) 1988-05-19 1989-09-19 The Standard Oil Company Olefinic aryl oxime derivatives of hydantoins
TW432073B (en) 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
GB2324087A (en) * 1997-04-10 1998-10-14 Merck & Co Inc Preparation of (S)-3-Carbethoxy-3-benzylpiperidine
WO1998058947A1 (en) * 1997-06-25 1998-12-30 Pfizer Inc. Dipeptide derivatives as growth hormone secretagogues
US6358951B1 (en) * 1998-08-21 2002-03-19 Pfizer Inc. Growth hormone secretagogues
US6297380B1 (en) 1998-11-23 2001-10-02 Pfizer Inc. Process and intermediates for growth hormone secretagogues

Also Published As

Publication number Publication date
US6686471B2 (en) 2004-02-03
US20030225280A1 (en) 2003-12-04
AU5958499A (en) 2000-05-25
HUP9904384A2 (hu) 2000-08-28
CN1255498A (zh) 2000-06-07
US20030088097A1 (en) 2003-05-08
CA2290252C (en) 2004-08-24
DE69919663T2 (de) 2005-09-01
JP3488155B2 (ja) 2004-01-19
JP2003012672A (ja) 2003-01-15
PL336710A1 (en) 2000-06-05
ZA997227B (en) 2001-05-22
PT1004583E (pt) 2004-12-31
DK1004583T3 (da) 2004-12-13
US6297380B1 (en) 2001-10-02
BR9905732A (pt) 2001-03-20
EP1004583A3 (de) 2000-06-14
DE69919663D1 (de) 2004-09-30
EP1004583A2 (de) 2000-05-31
EP1004583B1 (de) 2004-08-25
US20020010335A1 (en) 2002-01-24
US6465651B2 (en) 2002-10-15
US6603002B2 (en) 2003-08-05
ID23852A (id) 2000-05-25
HUP9904384A3 (en) 2002-04-29
HU9904384D0 (en) 2000-01-28
JP2000159770A (ja) 2000-06-13
AR019498A1 (es) 2002-02-20
IL133043A0 (en) 2001-03-19
KR20000035568A (ko) 2000-06-26
TR199902879A2 (xx) 2000-06-21
CA2290252A1 (en) 2000-05-23
ES2226297T3 (es) 2005-03-16

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