ATE274585T1 - Dna - kette zur synthese von xanthophyll und prozess zur herstellung von xanthophyll - Google Patents
Dna - kette zur synthese von xanthophyll und prozess zur herstellung von xanthophyllInfo
- Publication number
- ATE274585T1 ATE274585T1 AT95903959T AT95903959T ATE274585T1 AT E274585 T1 ATE274585 T1 AT E274585T1 AT 95903959 T AT95903959 T AT 95903959T AT 95903959 T AT95903959 T AT 95903959T AT E274585 T1 ATE274585 T1 AT E274585T1
- Authority
- AT
- Austria
- Prior art keywords
- xanthophyll
- group
- synthesis
- encodes
- polypeptide
- Prior art date
Links
- 235000008210 xanthophylls Nutrition 0.000 title abstract 5
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 title 2
- 229960005375 lutein Drugs 0.000 title 2
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 title 2
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 title 2
- 108020004414 DNA Proteins 0.000 abstract 5
- 102000053602 DNA Human genes 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- 125000000468 ketone group Chemical group 0.000 abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 150000003735 xanthophylls Chemical class 0.000 abstract 3
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 abstract 2
- 235000013793 astaxanthin Nutrition 0.000 abstract 2
- 239000001168 astaxanthin Substances 0.000 abstract 2
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 abstract 2
- 229940022405 astaxanthin Drugs 0.000 abstract 2
- FDSDTBUPSURDBL-LOFNIBRQSA-N canthaxanthin Chemical compound CC=1C(=O)CCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)CCC1(C)C FDSDTBUPSURDBL-LOFNIBRQSA-N 0.000 abstract 2
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 2
- HFRZSVYKDDZRQY-AATRIKPKSA-N 3-Hydroxy-beta-ionone Chemical group CC(=O)\C=C\C1=C(C)CC(O)CC1(C)C HFRZSVYKDDZRQY-AATRIKPKSA-N 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- OOUTWVMJGMVRQF-DOYZGLONSA-N Phoenicoxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C(=O)C(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)C(=O)CCC2(C)C OOUTWVMJGMVRQF-DOYZGLONSA-N 0.000 abstract 1
- PSQYTAPXSHCGMF-BQYQJAHWSA-N beta-ionone group Chemical group CC1=C(C(CCC1)(C)C)/C=C/C(C)=O PSQYTAPXSHCGMF-BQYQJAHWSA-N 0.000 abstract 1
- 235000012682 canthaxanthin Nutrition 0.000 abstract 1
- 239000001659 canthaxanthin Substances 0.000 abstract 1
- 229940008033 canthaxanthin Drugs 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0093—Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34873793 | 1993-12-27 | ||
| JP23591794 | 1994-09-05 | ||
| PCT/JP1994/002220 WO1995018220A1 (en) | 1993-12-27 | 1994-12-26 | Dna chain useful for xanthophyll synthesis and process for producing xanthophylls |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274585T1 true ATE274585T1 (de) | 2004-09-15 |
Family
ID=26532393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95903959T ATE274585T1 (de) | 1993-12-27 | 1994-12-26 | Dna - kette zur synthese von xanthophyll und prozess zur herstellung von xanthophyll |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US5811273A (de) |
| EP (2) | EP0735137B1 (de) |
| JP (1) | JP3375639B2 (de) |
| KR (1) | KR100231454B1 (de) |
| AT (1) | ATE274585T1 (de) |
| AU (1) | AU702584B2 (de) |
| CA (1) | CA2180024C (de) |
| DE (1) | DE69433969T2 (de) |
| ES (1) | ES2225836T3 (de) |
| FI (1) | FI962633A7 (de) |
| NO (1) | NO962689L (de) |
| WO (1) | WO1995018220A1 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0725137B2 (de) * | 1994-08-23 | 2005-03-02 | Kirin Beer Kabushiki Kaisha | Ketogruppe-einführendes enzym, dafür kodierende dna und verfahren zur herstellung von ketocarotenoid |
| DE69526842T3 (de) * | 1994-08-23 | 2005-10-27 | Kirin Beer K.K. | Ketogruppe-einführendes enzym, dafür kodierende dna und verfahren zur herstellung von ketocarotenoid |
| JP2960967B2 (ja) | 1994-08-23 | 1999-10-12 | 麒麟麦酒株式会社 | ケト基導入酵素,それをコードするdnaおよびケトカロチノイドの製造法 |
| US6642021B2 (en) | 1996-03-29 | 2003-11-04 | University Of Maryland | Methods of producing carotenoids by the expression of plant ε-cyclase genes |
| US6429356B1 (en) | 1996-08-09 | 2002-08-06 | Calgene Llc | Methods for producing carotenoid compounds, and specialty oils in plant seeds |
| EP0872554B1 (de) | 1996-12-02 | 2003-06-11 | F. Hoffmann-La Roche Ag | Verbesserte fermentative Herstellung von Carotenoide |
| US6653530B1 (en) | 1998-02-13 | 2003-11-25 | Calgene Llc | Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds |
| US6551807B1 (en) | 1998-05-22 | 2003-04-22 | University Of Maryland | Carotenoid ketolase genes and gene products, production of ketocarotenoids and methods of modifying carotenoids using the genes |
| DE19916140A1 (de) | 1999-04-09 | 2000-10-12 | Basf Ag | Carotinhydroxylase und Verfahren zur Herstellung von Xanthophyllderivaten |
| PT1190068E (pt) | 1999-04-15 | 2006-06-30 | Calgene Llc | Sequencias de acidos nucleicos para proteinas envolvidas na sintese de tocoferol |
| US6872815B1 (en) | 2000-10-14 | 2005-03-29 | Calgene Llc | Nucleic acid sequences to proteins involved in tocopherol synthesis |
| EP1356033B1 (de) | 2000-08-07 | 2009-10-28 | Monsanto Technology LLC | Am methyl-d-erythriol phosphat reaktionsweg beteiligte gene |
| EP1377598A4 (de) * | 2001-01-26 | 2005-08-03 | Cargill Inc | Carotinoid-biosynthese |
| US20050003474A1 (en) * | 2001-01-26 | 2005-01-06 | Desouza Mervyn L. | Carotenoid biosynthesis |
| US20040078846A1 (en) * | 2002-01-25 | 2004-04-22 | Desouza Mervyn L. | Carotenoid biosynthesis |
| US7161061B2 (en) | 2001-05-09 | 2007-01-09 | Monsanto Technology Llc | Metabolite transporters |
| AU2002257237B8 (en) | 2001-05-09 | 2008-06-05 | Monsanto Technology Llc | Tyra genes and uses thereof |
| US7081478B2 (en) * | 2001-06-29 | 2006-07-25 | Chrysantis, Inc. | Mixed zeaxanthin ester concentrate and uses thereof |
| US6784351B2 (en) * | 2001-06-29 | 2004-08-31 | Ball Horticultural Company | Targetes erecta marigolds with altered carotenoid compositions and ratios |
| US7575766B2 (en) * | 2001-06-29 | 2009-08-18 | Ball Horticultural Company | Tagetes erecta with altered carotenoid compositions and ratios |
| US7244877B2 (en) | 2001-08-17 | 2007-07-17 | Monsanto Technology Llc | Methyltransferase from cotton and uses thereof |
| WO2003034812A2 (en) | 2001-10-25 | 2003-05-01 | Monsanto Technology Llc | Aromatic methyltransferases and uses thereof |
| BR0308740A (pt) | 2002-03-19 | 2007-01-09 | Monsanto Technology Llc | ácidos nucléicos e polipeptìdeos de homogentisado prenil transferase ("hpt"), e empregos destes |
| US7223909B2 (en) * | 2002-03-21 | 2007-05-29 | Ball Horticultural | 4-ketocarotenoids in flower petals |
| AU2003268083A1 (en) | 2002-08-05 | 2004-02-23 | Monsanto Technology, Llc | Tocopherol biosynthesis related genes and uses thereof |
| WO2004018694A2 (de) * | 2002-08-20 | 2004-03-04 | Sungene Gmbh & Co. Kgaa | Verfahren zur herstellung von ketocarotinoiden in genetisch veränderten organismen |
| GB0227730D0 (en) * | 2002-11-28 | 2003-01-08 | Aquapharm Bio Discovery Ltd | Novel production of biocompounds |
| US7663021B2 (en) | 2002-12-06 | 2010-02-16 | Del Monte Fresh Produce Company | Transgenic pineapple plants with modified carotenoid levels and methods of their production |
| DE10300649A1 (de) * | 2003-01-09 | 2004-07-22 | Basf Ag | Verfahren zur Herstellung von Ketocarotinoiden durch Kultivierung von genetisch veränderten Organismen |
| WO2005062867A2 (en) * | 2003-12-19 | 2005-07-14 | E.I. Dupont De Nemours And Company | Novel carotenoids ketolases |
| US7999151B2 (en) * | 2004-06-04 | 2011-08-16 | Kirin Holdings Kabushiki Kaisha | Method of producing astaxanthin or metabolic product thereof by using carotenoid ketolase and carotenoid hydroxylase genes |
| US7091031B2 (en) * | 2004-08-16 | 2006-08-15 | E. I. Du Pont De Nemours And Company | Carotenoid hydroxylase enzymes |
| US7547945B2 (en) * | 2004-09-01 | 2009-06-16 | Micron Technology, Inc. | Transistor devices, transistor structures and semiconductor constructions |
| EP2133424A1 (de) | 2004-11-29 | 2009-12-16 | Kirin Beer Kabushiki Kaisha | Peptidtransport zu den Chromoplasten in Blütenblättern und Verfahren zur Bildung einer Pflanze mit gelblichen Blütenblättern damit |
| EP1974049A2 (de) | 2004-12-17 | 2008-10-01 | Metanomics GmbH | Verfahren zur steuerung der produktion von feinchemikalien |
| US7074604B1 (en) * | 2004-12-29 | 2006-07-11 | E. I. Du Pont De Nemours And Company | Bioproduction of astaxanthin using mutant carotenoid ketolase and carotenoid hydroxylase genes |
| CA2598792A1 (en) | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| WO2006096392A2 (en) * | 2005-03-04 | 2006-09-14 | Diversa Corporation | Enzymes involved in astaxanthin, carotenoid and isoprenoid biosynthetic pathways, genes encoding them and methods of making and using them |
| CN101218352B (zh) | 2005-03-18 | 2013-09-04 | 米克罗比亚公司 | 产油酵母和真菌中类胡萝卜素的产生 |
| EP1874110A4 (de) | 2005-04-15 | 2009-06-10 | Del Monte Fresh Produce Compan | Pflanzliche promoter, terminatoren, gene, vektoren und damit in zusammenhang stehende transformierte pflanzen |
| DE602005022120D1 (de) * | 2005-07-19 | 2010-08-12 | Cj Cheiljedang Corp | Mikroorganismus der gattung enterobacteriacae mit genen in zusammenhang mit der biosynthese von l-carnitin sowie verfahren zur produktion von l-carnitin mit dem mikroorganismus |
| US8883969B2 (en) * | 2005-10-28 | 2014-11-11 | Tosoh Corporation | Method for production of carotenoid-synthesizing microorganism and method for production of carotenoid |
| US7393671B2 (en) * | 2006-03-30 | 2008-07-01 | E.I. Du Pont De Nemours And Company | Mutant carotenoid ketolases |
| US7422873B2 (en) * | 2006-03-31 | 2008-09-09 | E.I. Du Pont De Nemours And Company | Mutant carotenoid ketolase |
| US8691555B2 (en) | 2006-09-28 | 2014-04-08 | Dsm Ip Assests B.V. | Production of carotenoids in oleaginous yeast and fungi |
| US20140123339A1 (en) | 2012-10-31 | 2014-05-01 | Pioneer Hi Bred International Inc | Transformed Plants Having Increased Beta-Carotene Levels, Increased Half-Life and Bioavailability and Methods of Producing Such |
| KR102113368B1 (ko) | 2012-12-20 | 2020-05-22 | 디에스엠 아이피 어셋츠 비.브이. | 카로틴 수산화효소 및 이의 카로티노이드 생산에 있어서의 용도 |
| JP2019165635A (ja) * | 2016-08-10 | 2019-10-03 | 味の素株式会社 | L−アミノ酸の製造法 |
| US12447202B2 (en) | 2018-05-17 | 2025-10-21 | Lumen Bioscience, Inc. | Arthrospira platensis oral vaccine delivery platform |
| WO2020018586A1 (en) | 2018-07-16 | 2020-01-23 | Lumen Bioscience, Inc. | Thermostable phycobiliproteins produced in spirulina |
| WO2021003456A1 (en) | 2019-07-03 | 2021-01-07 | Lumen Bioscience, Inc. | Arthrospira platensis non-parenteral therapeutic delivery platform |
| US11851664B2 (en) | 2020-12-24 | 2023-12-26 | Oakbio, Inc. | Methods for producing biochemicals using enzyme genes derived from a strain of Brevundimonas, and compositions made thereby |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0393690B1 (de) * | 1989-04-21 | 1995-03-29 | Kirin Beer Kabushiki Kaisha | Zur Synthese von Karotinoiden verwendbare DNA-Sequenzen |
| CA2047000A1 (en) * | 1990-07-20 | 1992-01-21 | John W. Chapman | Astaxanthin-generating yeast cells |
| NZ248628A (en) * | 1992-09-11 | 1996-02-27 | Gist Brocades Nv | Transformed phaffia (yeast) strains and methods and vectors used |
| EP0725137B2 (de) * | 1994-08-23 | 2005-03-02 | Kirin Beer Kabushiki Kaisha | Ketogruppe-einführendes enzym, dafür kodierende dna und verfahren zur herstellung von ketocarotenoid |
-
1994
- 1994-12-26 DE DE69433969T patent/DE69433969T2/de not_active Expired - Lifetime
- 1994-12-26 WO PCT/JP1994/002220 patent/WO1995018220A1/ja not_active Ceased
- 1994-12-26 KR KR1019960703383A patent/KR100231454B1/ko not_active Expired - Fee Related
- 1994-12-26 US US08/663,310 patent/US5811273A/en not_active Expired - Lifetime
- 1994-12-26 ES ES95903959T patent/ES2225836T3/es not_active Expired - Lifetime
- 1994-12-26 EP EP95903959A patent/EP0735137B1/de not_active Expired - Lifetime
- 1994-12-26 CA CA002180024A patent/CA2180024C/en not_active Expired - Fee Related
- 1994-12-26 EP EP01121660A patent/EP1203818A3/de not_active Withdrawn
- 1994-12-26 AU AU12811/95A patent/AU702584B2/en not_active Ceased
- 1994-12-26 JP JP51790895A patent/JP3375639B2/ja not_active Expired - Fee Related
- 1994-12-26 AT AT95903959T patent/ATE274585T1/de not_active IP Right Cessation
-
1996
- 1996-06-26 NO NO962689A patent/NO962689L/no not_active Application Discontinuation
- 1996-06-26 FI FI962633A patent/FI962633A7/fi not_active IP Right Cessation
-
1998
- 1998-01-13 US US09/006,491 patent/US5972690A/en not_active Expired - Lifetime
-
1999
- 1999-06-18 US US09/335,919 patent/US6150130A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6150130A (en) | 2000-11-21 |
| US5972690A (en) | 1999-10-26 |
| DE69433969T2 (de) | 2005-08-11 |
| EP1203818A3 (de) | 2002-06-12 |
| JP3375639B2 (ja) | 2003-02-10 |
| US5811273A (en) | 1998-09-22 |
| EP0735137A1 (de) | 1996-10-02 |
| CA2180024A1 (en) | 1995-07-06 |
| FI962633A0 (fi) | 1996-06-26 |
| CA2180024C (en) | 2002-03-19 |
| NO962689D0 (no) | 1996-06-26 |
| DE69433969D1 (de) | 2004-09-30 |
| KR100231454B1 (ko) | 1999-12-01 |
| FI962633A7 (fi) | 1996-08-23 |
| EP0735137A4 (de) | 1998-12-02 |
| WO1995018220A1 (en) | 1995-07-06 |
| NO962689L (no) | 1996-08-27 |
| ES2225836T3 (es) | 2005-03-16 |
| AU702584B2 (en) | 1999-02-25 |
| EP1203818A2 (de) | 2002-05-08 |
| EP0735137B1 (de) | 2004-08-25 |
| AU1281195A (en) | 1995-07-17 |
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