ATE275135T1 - Verfahren zur herstellung eines n-substituierten heterocyclischen derivats unterverwendung eines phasentransfer-katalysators - Google Patents

Verfahren zur herstellung eines n-substituierten heterocyclischen derivats unterverwendung eines phasentransfer-katalysators

Info

Publication number: ATE275135T1
Authority: AT; Austria
Prior art keywords: substituted heterocyclic; phase transfer; producing; transfer catalyst; heterocyclic derivative
Prior art date: 1998-01-30

Application number

AT99904158T

Other languages

English (en)

Inventor

Neal G Anderson

Rajendra Deshpande

Jerome L Moniot

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-30

Filing date

1999-01-20

Publication date

2004-09-15

1999-01-20 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2004-09-15 Application granted granted Critical

2004-09-15 Publication of ATE275135T1 publication Critical patent/ATE275135T1/de

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
239000003444 phase transfer catalyst Substances 0.000 title 1
125000000623 heterocyclic group Chemical class 0.000 abstract 1
238000003408 phase transfer catalysis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT99904158T 1998-01-30 1999-01-20 Verfahren zur herstellung eines n-substituierten heterocyclischen derivats unterverwendung eines phasentransfer-katalysators ATE275135T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7310398P	1998-01-30	1998-01-30
PCT/US1999/001201 WO1999038847A1 (en)	1998-01-30	1999-01-20	Method for preparing n-substituted heterocyclic derivatives using a phase-transfer catalyst

Publications (1)

Publication Number	Publication Date
ATE275135T1 true ATE275135T1 (de)	2004-09-15

Family

ID=22111745

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99904158T ATE275135T1 (de)	1998-01-30	1999-01-20	Verfahren zur herstellung eines n-substituierten heterocyclischen derivats unterverwendung eines phasentransfer-katalysators

Country Status (15)

Country	Link
US (1)	US6162922A (de)
EP (1)	EP1060165B1 (de)
JP (2)	JP4441114B2 (de)
KR (1)	KR100546530B1 (de)
AT (1)	ATE275135T1 (de)
AU (1)	AU743018B2 (de)
CA (1)	CA2318791A1 (de)
DE (1)	DE69919849T2 (de)
DK (1)	DK1060165T3 (de)
ES (1)	ES2228006T3 (de)
HU (1)	HU226770B1 (de)
IL (1)	IL136357A (de)
PT (1)	PT1060165E (de)
TW (1)	TWI229076B (de)
WO (1)	WO1999038847A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU218680B (hu) *	1997-07-25	2000-10-30	Sanofi-Synthelabo	Eljárás 1,3-diaza-spiro[4,4]non-1-én-4-on-származékok előállítására és 1-ciano-1-(acil-amino)-ciklopentán intermedierek
CN1668612A (zh) *	2002-07-16	2005-09-14	特瓦制药工业有限公司	厄贝沙坦的新合成方法
WO2005051943A1 (en) *	2003-11-28	2005-06-09	Ranbaxy Laboratories Limited	Processes for the preparation of highly pure irbesartan
EP1751123A4 (de) *	2004-05-20	2010-06-30	Reddys Lab Ltd Dr	Verfahren zur herstellung von irbesartan
DE602005025755D1 (de)	2004-06-04	2011-02-17	Teva Pharma	Irbesartan enthaltende pharmazeutische zusammensetzung
SI21848A (sl) *	2004-07-29	2006-02-28	Krka, Tovarna Zdravil, D.D., Novo Mesto	Priprava seskvihidratne hidrokloridne soli tetrazolskega derivata
TWI346108B (en) *	2004-08-23	2011-08-01	Bristol Myers Squibb Co	A method for preparing irbesartan and intermediates thereof
GB2419592A (en) *	2004-10-26	2006-05-03	Cipla Ltd	Process for the preparation of irbesartan hydrochloride
ES2259909B1 (es) *	2005-02-28	2007-06-16	Inke, S.A.	Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de su intermedio de sintesis.
WO2007013101A1 (en) *	2005-07-27	2007-02-01	Jubilant Organosys Limited	PROCESS FOR PRODUCING 2-(N-BUTYL)-3-[[2'-(TETRAZOL-5-YL)BIPHENYL- 4-YL]METHYL]-l,3-DIAZASPIRO[4.4] NON-1-EN-4-ONE
EP1764365A1 (de)	2005-09-20	2007-03-21	KRKA, D.D., Novo Mesto	Verfahren zur Herstellung Sartanderivate und Zwischenprodukte für dieses Verfahren
ES2371910T3 (es)	2006-04-07	2012-01-11	Lek Pharmaceuticals D.D.	Procedimiento para la preparación de irbesartán puro.
CN100413853C (zh) *	2006-09-21	2008-08-27	浙江海正药业股份有限公司	厄贝沙坦的合成中间体及其制备方法和制备药物的用途
WO2008087401A1 (en) *	2007-01-18	2008-07-24	Rainbow Engineering Services	Sulfate salts of irbesartan and their preparation and pharmaceutical compositions
US7671273B2 (en)	2007-10-09	2010-03-02	International Business Machines Corporation	Method and apparatus for facilitating signal transmission using differential transmission lines
EP2417110B1 (de) *	2009-04-08	2014-05-07	CTX Life Sciences Pvt. Ltd.	Eintopfverfahren zur herstellung von 2-butyl-3-[[2'-(1h-tetrazol-5-yl)[1,1'- biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4] non-1-en-4-on (irbesartan)
CN101781287B (zh) *	2010-03-26	2013-03-20	天津大学	一种厄贝沙坦氢溴酸盐及其制备方法
CN110487931B (zh) *	2019-08-21	2024-10-01	浙江华海药业股份有限公司	一种(e)-4-苯基-4-氧代-2-丁烯酸乙酯的分析方法
WO2022094148A1 (en)	2020-10-30	2022-05-05	Encodia, Inc.	Conjugation reagents and methods using 1,2-cyclohexanediones

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5270317A (en) *	1990-03-20	1993-12-14	Elf Sanofi	N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
TW201738B (de) *	1990-03-20	1993-03-11	Sanofi Co
IL99372A0 (en) *	1990-09-10	1992-08-18	Ciba Geigy Ag	Azacyclic compounds
US5126342A (en) *	1990-10-01	1992-06-30	Merck & Co., Inc.	Imidazole angiotensin ii antagonists incorporating acidic functional groups
FR2673427B1 (fr) *	1991-03-01	1993-06-18	Sanofi Elf	Derives heterocycliques diazotes n-substitues par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
WO1993004045A1 (en) *	1991-08-19	1993-03-04	E.I. Du Pont De Nemours And Company	Angiotensin ii receptor blocking imidazolinone derivatives
FR2688781B1 (fr) *	1992-03-23	1994-07-01	Sanofi Elf	Imidazolines n-substituees par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
FR2689887B1 (fr) *	1992-04-13	1995-06-23	Sanofi Elf	Procede de preparation d'un derive de biphenyle.
JP2707390B2 (ja) *	1992-05-22	1998-01-28	壽製薬株式会社	シクロヘプトイミダゾ−ル誘導体及びその製造方法並びにこれを含有する薬剤
US5612363A (en) *	1995-06-02	1997-03-18	Berlex Laboratories, Inc.	N,N-di(aryl) cyclic urea derivatives as anti-coagulants

1999
- 1999-01-19 US US09/233,238 patent/US6162922A/en not_active Expired - Lifetime
- 1999-01-20 EP EP99904158A patent/EP1060165B1/de not_active Expired - Lifetime
- 1999-01-20 JP JP2000530084A patent/JP4441114B2/ja not_active Expired - Lifetime
- 1999-01-20 HU HU0100898A patent/HU226770B1/hu unknown
- 1999-01-20 DK DK99904158T patent/DK1060165T3/da active
- 1999-01-20 AU AU24615/99A patent/AU743018B2/en not_active Expired
- 1999-01-20 KR KR1020007008302A patent/KR100546530B1/ko not_active Expired - Lifetime
- 1999-01-20 IL IL13635799A patent/IL136357A/en not_active IP Right Cessation
- 1999-01-20 WO PCT/US1999/001201 patent/WO1999038847A1/en not_active Ceased
- 1999-01-20 DE DE69919849T patent/DE69919849T2/de not_active Expired - Lifetime
- 1999-01-20 ES ES99904158T patent/ES2228006T3/es not_active Expired - Lifetime
- 1999-01-20 PT PT99904158T patent/PT1060165E/pt unknown
- 1999-01-20 CA CA002318791A patent/CA2318791A1/en not_active Abandoned
- 1999-01-20 AT AT99904158T patent/ATE275135T1/de active
- 1999-01-26 TW TW088101130A patent/TWI229076B/zh not_active IP Right Cessation
2009
- 2009-10-28 JP JP2009247745A patent/JP2010018638A/ja active Pending

Also Published As

Publication number	Publication date
KR20010034477A (ko)	2001-04-25
TWI229076B (en)	2005-03-11
EP1060165A1 (de)	2000-12-20
IL136357A (en)	2004-07-25
HU226770B1 (en)	2009-09-28
HUP0100898A3 (en)	2002-03-28
JP2010018638A (ja)	2010-01-28
JP2002501946A (ja)	2002-01-22
HUP0100898A2 (hu)	2002-02-28
WO1999038847A1 (en)	1999-08-05
KR100546530B1 (ko)	2006-01-26
AU743018B2 (en)	2002-01-17
US6162922A (en)	2000-12-19
AU2461599A (en)	1999-08-16
EP1060165B1 (de)	2004-09-01
PT1060165E (pt)	2004-12-31
DK1060165T3 (da)	2004-11-22
ES2228006T3 (es)	2005-04-01
DE69919849T2 (de)	2005-09-22
CA2318791A1 (en)	1999-08-05
DE69919849D1 (de)	2004-10-07
EP1060165A4 (de)	2002-07-31
JP4441114B2 (ja)	2010-03-31

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2005-08-15

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