ATE275415T1 - Zusamenzetzung enthaltend einen inhibitor des myelin assoziierten glycoproteins (mag), welcher einer veränderten oder mutierten form von mag enthält - Google Patents
Zusamenzetzung enthaltend einen inhibitor des myelin assoziierten glycoproteins (mag), welcher einer veränderten oder mutierten form von mag enthältInfo
- Publication number
- ATE275415T1 ATE275415T1 AT96923524T AT96923524T ATE275415T1 AT E275415 T1 ATE275415 T1 AT E275415T1 AT 96923524 T AT96923524 T AT 96923524T AT 96923524 T AT96923524 T AT 96923524T AT E275415 T1 ATE275415 T1 AT E275415T1
- Authority
- AT
- Austria
- Prior art keywords
- mag
- methods
- neural
- regeneration
- myelin
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 102000017099 Myelin-Associated Glycoprotein Human genes 0.000 title abstract 3
- 108010013731 Myelin-Associated Glycoprotein Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 6
- 230000001537 neural effect Effects 0.000 abstract 6
- 230000008929 regeneration Effects 0.000 abstract 5
- 238000011069 regeneration method Methods 0.000 abstract 5
- 102100021831 Myelin-associated glycoprotein Human genes 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 231100000858 damage to nervous tissue Toxicity 0.000 abstract 1
- 230000007850 degeneration Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 230000007514 neuronal growth Effects 0.000 abstract 1
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Marine Sciences & Fisheries (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56195P | 1995-06-27 | 1995-06-27 | |
| PCT/US1996/011058 WO1997001352A1 (en) | 1995-06-27 | 1996-06-27 | Compositions and methods using myelin-associated glycoprotein (mag) and inhibitors thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275415T1 true ATE275415T1 (de) | 2004-09-15 |
Family
ID=21692042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96923524T ATE275415T1 (de) | 1995-06-27 | 1996-06-27 | Zusamenzetzung enthaltend einen inhibitor des myelin assoziierten glycoproteins (mag), welcher einer veränderten oder mutierten form von mag enthält |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US5932542A (de) |
| EP (1) | EP0835127B1 (de) |
| JP (2) | JP4841017B2 (de) |
| AT (1) | ATE275415T1 (de) |
| AU (1) | AU731044B2 (de) |
| CA (1) | CA2225691A1 (de) |
| DE (1) | DE69633336T2 (de) |
| WO (1) | WO1997001352A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE275415T1 (de) * | 1995-06-27 | 2004-09-15 | Res Foundation Of Cuny Hunter | Zusamenzetzung enthaltend einen inhibitor des myelin assoziierten glycoproteins (mag), welcher einer veränderten oder mutierten form von mag enthält |
| WO1999020190A1 (en) * | 1997-10-23 | 1999-04-29 | President And Fellows Of Harvard College | Laser inactivation of inhibitory molecules in central nervous sy stem myelin |
| US20030108528A1 (en) * | 1998-05-19 | 2003-06-12 | Michal Eisenbach-Schwartz | Activated t-cells, nervous system-specific antigens and their uses |
| CA2328612A1 (en) * | 1998-05-19 | 1999-11-25 | Yeda Research And Development Co., Ltd. | Activated t cells, nervous system-specific antigens and their uses |
| AU5339699A (en) * | 1998-08-06 | 2000-02-28 | Johns Hopkins University School Of Medicine, The | Compounds for altering cell surface sialic acids and methods of use therefor |
| DE60137414D1 (de) | 2000-05-05 | 2009-03-05 | Univ City | Zusammensetzungen zur stimulierung der regeneration und der wiederherstellung des nervensystems durch regulierung der arginase 1- und polyamin-synthese |
| EP1343528A2 (de) * | 2000-11-02 | 2003-09-17 | Research Foundation of City University of New York | Methoden zur stimulierung der regeneration und reparatur des nervensystems durch hemmung der phosphodiesterase typ 4 |
| GB0103174D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Plc | Novel method of treatment |
| TWI323265B (en) * | 2002-08-06 | 2010-04-11 | Glaxo Group Ltd | Antibodies |
| US7842666B2 (en) * | 2002-12-20 | 2010-11-30 | Research Foundation Of City University Of New York | Inhibitors of myelin-associated glycoprotein (MAG) activity for regulating neural growth and regeneration |
| GB0306309D0 (en) | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
| JP2008545705A (ja) * | 2005-05-25 | 2008-12-18 | ザ・ジョンズ・ホプキンス・ユニバーシティ | 軸索再生を促進する組成物及び方法 |
| GB0525662D0 (en) | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Immunoglobulins |
| WO2007117440A2 (en) * | 2006-03-30 | 2007-10-18 | Research Foundation Of City University Of New York | Stimulation of neuron regeneration by secretory leukocyte protease inhibitor |
| US8974782B2 (en) | 2011-02-07 | 2015-03-10 | Glaxo Group Limited | Treatment of stroke comprising anti-MAG antibodies |
| US9937242B2 (en) | 2012-04-09 | 2018-04-10 | Case Western Reserve University | Compositions and methods for inhibiting the activity of LAR family phosphatases |
| US11229789B2 (en) | 2013-05-30 | 2022-01-25 | Neurostim Oab, Inc. | Neuro activator with controller |
| WO2014194200A1 (en) | 2013-05-30 | 2014-12-04 | Creasey Graham H | Topical neurological stimulation |
| US11077301B2 (en) | 2015-02-21 | 2021-08-03 | NeurostimOAB, Inc. | Topical nerve stimulator and sensor for bladder control |
| US10280386B2 (en) | 2015-04-03 | 2019-05-07 | Ecolab Usa Inc. | Enhanced peroxygen stability in multi-dispense TAED-containing peroxygen solid |
| HK1259294A1 (zh) * | 2015-11-10 | 2019-11-29 | 耶鲁大学 | 用於治疗自身免疫疾病和癌症的组合物及方法 |
| EP3706856A4 (de) | 2017-11-07 | 2021-08-18 | Neurostim Oab, Inc. | Nicht-invasiver nervenaktivator mit adaptiver schaltung |
| EP4349951B1 (de) | 2018-06-15 | 2026-03-18 | Ecolab USA Inc. | Verbesserte persauerstoffstabilität unter verwendung von fettsäure in einem persauerstofffeststoff enthaltenden bleichaktivator |
| US11458311B2 (en) | 2019-06-26 | 2022-10-04 | Neurostim Technologies Llc | Non-invasive nerve activator patch with adaptive circuit |
| KR20220115802A (ko) | 2019-12-16 | 2022-08-18 | 뉴로스팀 테크놀로지스 엘엘씨 | 부스트 전하 전달 기능이 있는 비침습적 신경 액티베이터 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250414A (en) * | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
| GB9403250D0 (en) * | 1994-02-21 | 1994-04-13 | Univ Mcgill | Therapeutic use of myelin-associated glycoprotein (mag) |
| ATE275415T1 (de) * | 1995-06-27 | 2004-09-15 | Res Foundation Of Cuny Hunter | Zusamenzetzung enthaltend einen inhibitor des myelin assoziierten glycoproteins (mag), welcher einer veränderten oder mutierten form von mag enthält |
-
1996
- 1996-06-27 AT AT96923524T patent/ATE275415T1/de not_active IP Right Cessation
- 1996-06-27 US US08/670,511 patent/US5932542A/en not_active Expired - Lifetime
- 1996-06-27 CA CA002225691A patent/CA2225691A1/en not_active Abandoned
- 1996-06-27 AU AU64012/96A patent/AU731044B2/en not_active Ceased
- 1996-06-27 DE DE69633336T patent/DE69633336T2/de not_active Expired - Lifetime
- 1996-06-27 EP EP96923524A patent/EP0835127B1/de not_active Expired - Lifetime
- 1996-06-27 JP JP50458997A patent/JP4841017B2/ja not_active Expired - Fee Related
- 1996-06-27 WO PCT/US1996/011058 patent/WO1997001352A1/en not_active Ceased
-
1999
- 1999-05-05 US US09/305,721 patent/US6203792B1/en not_active Expired - Lifetime
-
2001
- 2001-01-25 US US09/769,701 patent/US6399577B1/en not_active Expired - Lifetime
-
2008
- 2008-10-22 JP JP2008272034A patent/JP2009073845A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP4841017B2 (ja) | 2011-12-21 |
| US5932542A (en) | 1999-08-03 |
| DE69633336T2 (de) | 2005-09-22 |
| JP2009073845A (ja) | 2009-04-09 |
| AU731044B2 (en) | 2001-03-22 |
| JPH11508886A (ja) | 1999-08-03 |
| EP0835127B1 (de) | 2004-09-08 |
| DE69633336D1 (de) | 2004-10-14 |
| CA2225691A1 (en) | 1997-01-16 |
| EP0835127A1 (de) | 1998-04-15 |
| US6203792B1 (en) | 2001-03-20 |
| US6399577B1 (en) | 2002-06-04 |
| AU6401296A (en) | 1997-01-30 |
| WO1997001352A1 (en) | 1997-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0835127 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |