ATE275966T1 - Activin stimulator enthaltende pharmazeutische zusammensetzung - Google Patents

Activin stimulator enthaltende pharmazeutische zusammensetzung

Info

Publication number: ATE275966T1
Authority: AT; Austria
Prior art keywords: stimulator; pharmaceutical composition; composition containing; containing activin; activin
Prior art date: 1995-10-21

Application number

AT96935035T

Other languages

English (en)

Inventor

Mark William James Ferguson

Vale Furness

Original Assignee

Renovo Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-21

Filing date

1996-10-17

Publication date

2004-10-15

1996-10-17 Application filed by Renovo Ltd filed Critical Renovo Ltd

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE275966T1 publication Critical patent/ATE275966T1/de

Links

102000005606 Activins Human genes 0.000 title abstract 2
108010059616 Activins Proteins 0.000 title abstract 2
239000000488 activin Substances 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
206010052428 Wound Diseases 0.000 abstract 2
208000027418 Wounds and injury Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
230000003176 fibrotic effect Effects 0.000 abstract 2
230000035876 healing Effects 0.000 abstract 2
230000001737 promoting effect Effects 0.000 abstract 2
230000037390 scarring Effects 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 1
239000000893 inhibin Substances 0.000 abstract 1
ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Adornments (AREA)
Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
Absorbent Articles And Supports Therefor (AREA)

AT96935035T 1995-10-21 1996-10-17 Activin stimulator enthaltende pharmazeutische zusammensetzung ATE275966T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9521608A GB2306481A (en)	1995-10-21	1995-10-21	Pharmaceutical comprising a stimulator of activin and/or inhibin
PCT/GB1996/002559 WO1997015321A1 (en)	1995-10-21	1996-10-17	Pharmaceutical composition containing an activin or inhibin stimulator

Publications (1)

Publication Number	Publication Date
ATE275966T1 true ATE275966T1 (de)	2004-10-15

Family

ID=10782702

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96935035T ATE275966T1 (de)	1995-10-21	1996-10-17	Activin stimulator enthaltende pharmazeutische zusammensetzung

Country Status (13)

Country	Link
US (1)	US7713933B2 (de)
EP (1)	EP0855916B1 (de)
JP (1)	JP4102437B2 (de)
AT (1)	ATE275966T1 (de)
AU (1)	AU715255B2 (de)
CA (1)	CA2235412C (de)
DE (1)	DE69633396T2 (de)
DK (1)	DK0855916T3 (de)
ES (1)	ES2227610T3 (de)
GB (1)	GB2306481A (de)
PT (1)	PT855916E (de)
WO (1)	WO1997015321A1 (de)
ZA (1)	ZA968785B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU689184B2 (en)	1993-12-07	1998-03-26	Genetics Institute, Llc	BMP-12, BMP-13 and tendon-inducing compositions thereof
US6004937A (en) *	1998-03-09	1999-12-21	Genetics Institute, Inc.	Use of follistatin to modulate growth and differentiation factor 8 [GDF-8] and bone morphogenic protein 11 [BMP-11]
US6727224B1 (en)	1999-02-01	2004-04-27	Genetics Institute, Llc.	Methods and compositions for healing and repair of articular cartilage
DK1223990T3 (da)	1999-10-15	2004-11-29	Inst Genetics Llc	Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner
IL150198A0 (en) *	1999-12-15	2002-12-01	Res Dev Foundation	Betaglycan as an inhibin receptor and uses thereof
JP4487376B2 (ja)	2000-03-31	2010-06-23	味の素株式会社	腎疾患治療剤
US7226587B2 (en)	2001-06-01	2007-06-05	Wyeth	Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
TWI267378B (en)	2001-06-08	2006-12-01	Wyeth Corp	Calcium phosphate delivery vehicles for osteoinductive proteins
US8128933B2 (en)	2005-11-23	2012-03-06	Acceleron Pharma, Inc.	Method of promoting bone growth by an anti-activin B antibody
TW201803890A (zh)	2007-02-02	2018-02-01	艾瑟勒朗法瑪公司	衍生自ＡｃｔＲＩＩＢ的變體與其用途
GB0724231D0 (en) *	2007-12-12	2008-01-30	Renono Ltd	Methods for inhibiting scarring
CN102131822A (zh)	2008-06-26	2011-07-20	阿塞勒隆制药公司	进行激活素-ActRIIa拮抗剂给药和监测受治疗患者的方法
US8216997B2 (en)	2008-08-14	2012-07-10	Acceleron Pharma, Inc.	Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
US10010498B2 (en)	2014-06-04	2018-07-03	Acceleron Pharma Inc.	Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins
EA202090632A1 (ru)	2014-06-04	2020-07-31	Акселерон Фарма Инк.	Способы и композиции для лечения расстройств с использованием фоллистатиновых полипептидов
EP3274457A4 (de)	2015-03-26	2018-08-08	Acceleron Pharma Inc.	Follistatin-assoziierte fusionsproteine und verwendungen davon
WO2017088027A1 (en) *	2015-11-26	2017-06-01	Prince Henry's Institute Of Medical Research Trading As The Hudson Institute Of Medical Research	Inhibin analogs
CN115404199B (zh) *	2022-11-01	2023-03-21	广州优特佳生物科技发展有限公司	活化素b在促进透明质酸合成中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989011862A1 (en) *	1988-05-31	1989-12-14	Biotechnology Australia Pty. Ltd.	Actions of hormones
US5071834A (en) *	1988-09-16	1991-12-10	Genentech, Inc.	Purified activin B composition
US4997815A (en) *	1988-11-01	1991-03-05	Children's Hospital Medical Center Of Northern California	Method for augmenting fetal hemoglobin by treatment with activin and/or inhibin
JPH0651638B2 (ja) *	1989-02-13	1994-07-06	新技術事業団	角膜上皮創傷治療用点眼剤
US5102868A (en) *	1990-01-08	1992-04-07	Genentech, Inc.	Method for inhibiting follicular maturation
WO1991012334A1 (en) *	1990-02-15	1991-08-22	Cetus Corporation	Inhibitor of cytokine activity and applications thereof
US5216004A (en) *	1990-09-13	1993-06-01	Children's Hospital Medical Center Of North California	Method for preventing malaria
EP0548276A4 (en) *	1990-09-13	1993-12-29	Children's Hospital Medical Center Of Northern California	Method for increasing red blood cell production by treatment with activin or activin-related peptides
US5208219A (en) *	1991-02-14	1993-05-04	Celtrix Pharmaceuticals Inc.	Method for inducing bone growth
DK0575555T3 (da)	1991-03-11	2001-11-05	Curis Inc	Proteininduceret morfogenese
GB9106678D0 (en) *	1991-03-28	1991-05-15	Ferguson Mark W J	Wound healing
US5885794A (en)	1991-05-10	1999-03-23	The Salk Institute For Biological Studies	Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
IL99867A0 (en)	1991-10-27	1992-08-18	Yissum Res Dev Co	Pharmaceutical compositions containing activin a
GB9205800D0 (en) *	1992-03-17	1992-04-29	British Tech Group	Treatment of fibrotic disorders
GB9206861D0 (en) *	1992-03-28	1992-05-13	Univ Manchester	Wound healing and treatment of fibrotic disorders
US5428011A (en) *	1992-06-16	1995-06-27	Procyon Biopharma, Inc.	Pharmaceutical preparations for inhibiting tumours associated with prostate adenocarcinoma
US5888720A (en)	1992-10-27	1999-03-30	Yissum Research And Development Company Of The Hebrew University Of Jerusalem	In vitro micro-organs
US5753612A (en)	1992-10-27	1998-05-19	Yissum Research Development Co. Of The Hebrew University Of Jerusalem	Pharmaceutical composition and method for inhibiting hair growth by administration of activin or activin agonists
JPH07149659A (ja) *	1993-09-28	1995-06-13	Ajinomoto Co Inc	骨損傷治療剤
WO1995026203A1 (en) *	1994-03-29	1995-10-05	The Victoria University Of Manchester	Wound healing
FI971956L (fi)	1994-11-14	1997-07-04	Neurospheres Holdings Ltd	Hermosolujen lisääntymisen säännöstely

1995
- 1995-10-21 GB GB9521608A patent/GB2306481A/en not_active Withdrawn
1996
- 1996-10-17 WO PCT/GB1996/002559 patent/WO1997015321A1/en not_active Ceased
- 1996-10-17 EP EP96935035A patent/EP0855916B1/de not_active Expired - Lifetime
- 1996-10-17 AU AU73138/96A patent/AU715255B2/en not_active Ceased
- 1996-10-17 PT PT96935035T patent/PT855916E/pt unknown
- 1996-10-17 ES ES96935035T patent/ES2227610T3/es not_active Expired - Lifetime
- 1996-10-17 DE DE69633396T patent/DE69633396T2/de not_active Expired - Lifetime
- 1996-10-17 AT AT96935035T patent/ATE275966T1/de active
- 1996-10-17 JP JP51638897A patent/JP4102437B2/ja not_active Expired - Fee Related
- 1996-10-17 DK DK96935035T patent/DK0855916T3/da active
- 1996-10-17 CA CA002235412A patent/CA2235412C/en not_active Expired - Fee Related
- 1996-10-18 ZA ZA9608785A patent/ZA968785B/xx unknown
2003
- 2003-09-05 US US10/654,994 patent/US7713933B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ZA968785B (en)	1998-04-20
AU7313896A (en)	1997-05-15
DE69633396D1 (de)	2004-10-21
PT855916E (pt)	2004-11-30
DE69633396T2 (de)	2005-09-22
US20040052795A1 (en)	2004-03-18
GB2306481A (en)	1997-05-07
CA2235412A1 (en)	1997-05-01
EP0855916A1 (de)	1998-08-05
WO1997015321A1 (en)	1997-05-01
CA2235412C (en)	2010-01-19
JPH11514373A (ja)	1999-12-07
AU715255B2 (en)	2000-01-20
EP0855916B1 (de)	2004-09-15
DK0855916T3 (da)	2004-10-18
JP4102437B2 (ja)	2008-06-18
US7713933B2 (en)	2010-05-11
ES2227610T3 (es)	2005-04-01
GB9521608D0 (en)	1996-01-03

Legal Events

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2005-03-15

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