ATE275973T1 - Empfängnisverhütende zusammensetzungen die progestagen und progesteronantagonisten enthalten - Google Patents
Empfängnisverhütende zusammensetzungen die progestagen und progesteronantagonisten enthaltenInfo
- Publication number
- ATE275973T1 ATE275973T1 AT00928611T AT00928611T ATE275973T1 AT E275973 T1 ATE275973 T1 AT E275973T1 AT 00928611 T AT00928611 T AT 00928611T AT 00928611 T AT00928611 T AT 00928611T AT E275973 T1 ATE275973 T1 AT E275973T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- alkyl
- aminoalkyl
- alkoxy
- alkynyl
- Prior art date
Links
- 239000003433 contraceptive agent Substances 0.000 title 1
- 230000002254 contraceptive effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000044 progesterone antagonist Substances 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 5
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 230000000740 bleeding effect Effects 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004426 substituted alkynyl group Chemical group 0.000 abstract 2
- 201000000736 Amenorrhea Diseases 0.000 abstract 1
- 206010001928 Amenorrhoea Diseases 0.000 abstract 1
- 201000009030 Carcinoma Diseases 0.000 abstract 1
- 201000009273 Endometriosis Diseases 0.000 abstract 1
- 208000009956 adenocarcinoma Diseases 0.000 abstract 1
- 231100000540 amenorrhea Toxicity 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 235000012631 food intake Nutrition 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- -1 indoline derivative compounds Chemical class 0.000 abstract 1
- 230000002175 menstrual effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000001672 ovary Anatomy 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 201000010065 polycystic ovary syndrome Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000003998 progesterone receptors Human genes 0.000 abstract 1
- 108090000468 progesterone receptors Proteins 0.000 abstract 1
- 210000002307 prostate Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Display Devices Of Pinball Game Machines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30471299A | 1999-05-04 | 1999-05-04 | |
| US09/552,350 US6444668B1 (en) | 1999-05-04 | 2000-04-19 | Combination regimens using progesterone receptor modulators |
| PCT/US2000/011643 WO2000066164A1 (en) | 1999-05-04 | 2000-05-01 | Contraceptive compositions containing antiprogestinic and progestinic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275973T1 true ATE275973T1 (de) | 2004-10-15 |
Family
ID=26974177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00928611T ATE275973T1 (de) | 1999-05-04 | 2000-05-01 | Empfängnisverhütende zusammensetzungen die progestagen und progesteronantagonisten enthalten |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1173210B1 (de) |
| JP (1) | JP2002543155A (de) |
| CN (1) | CN1179753C (de) |
| AT (1) | ATE275973T1 (de) |
| AU (1) | AU4682000A (de) |
| CA (1) | CA2372773A1 (de) |
| DE (1) | DE60013798T2 (de) |
| DK (1) | DK1173210T3 (de) |
| ES (1) | ES2226833T3 (de) |
| HK (1) | HK1043736B (de) |
| MX (1) | MXPA01011311A (de) |
| PT (1) | PT1173210E (de) |
| SI (1) | SI1173210T1 (de) |
| WO (1) | WO2000066164A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP1699A (en) | 2001-03-21 | 2006-12-26 | Warner Lambert Co | New spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors |
| MXPA05003800A (es) | 2002-10-11 | 2005-06-08 | Ligand Pharm Inc | 5-(1¦,1¦-cicloalquil/alquenil)metiliden 1,2-dihidro-5h- cromeno[3,4f]quinolinas como compuestos moduladores de receptor de progesterona selectivos. |
| JP2006508076A (ja) | 2002-10-11 | 2006-03-09 | リガンド・ファーマシューティカルズ・インコーポレイテッド | 選択的プロゲステロン受容体モジュレーター化合物としての５−シクロアルケニル５Ｈ−クロメノ［３，４−ｆ］キノリン誘導体 |
| AR047398A1 (es) * | 2003-11-24 | 2006-01-18 | Wyeth Corp | Acoplamiento cruzado carbono- carbono catalizado por metales de transicion sobre soportes solidos |
| CA2563063C (en) * | 2004-04-27 | 2014-06-03 | Wyeth | Purification of progesterone receptor modulators |
| WO2006023158A2 (en) | 2004-07-14 | 2006-03-02 | Ligand Pharmaceuticals, Inc. | Mineralocorticoid receptor modulator compounds and methods, and pharmaceutical compositions containing these compounds |
| WO2006010142A2 (en) | 2004-07-14 | 2006-01-26 | Ligand Pharmaceuticals, Inc. | Mineralocorticoid receptor modulator compounds, processes for their preparation, and their use |
| EP1774970A1 (de) * | 2005-10-13 | 2007-04-18 | Bayer Schering Pharma AG | Verfahren zur Herstellung eines einphasigen pharmazeutischen Präparates zur Therapie der dysfunktionellen uterinen Blutung, enthaltend Ethinylestradiol und Dienogest |
| DE102008022221A1 (de) * | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3733478A1 (de) * | 1987-10-01 | 1989-04-13 | Schering Ag | Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore |
| DE4330234A1 (de) * | 1993-09-02 | 1995-03-09 | Schering Ag | Verwendung von Gestagenen und kompetitiven Progesteronantagonisten zur Herstellung von Arzneimitteln für die weibliche Fertilitätskontrolle sowie Mittel enthaltend ein Gestagen und einen kompetitiven Progesteronantagonisten |
| DE4344463A1 (de) * | 1993-12-22 | 1995-06-29 | Schering Ag | Kombinationsprodukt zur Kontrazeption |
| DE69532894T2 (de) * | 1994-11-22 | 2004-09-02 | Balance Pharmaceuticals, Inc., Pacific Palisades | Verfahren zur empfängnisverhütung |
| US5521166A (en) * | 1994-12-19 | 1996-05-28 | Ortho Pharmaceitical Corporation | Antiprogestin cyclophasic hormonal regimen |
| DE69710896T2 (de) * | 1996-06-25 | 2002-09-26 | Akzo Nobel N.V., Arnhem | Progestogen-anti-progestogen therapien |
-
2000
- 2000-05-01 PT PT00928611T patent/PT1173210E/pt unknown
- 2000-05-01 DE DE60013798T patent/DE60013798T2/de not_active Expired - Fee Related
- 2000-05-01 ES ES00928611T patent/ES2226833T3/es not_active Expired - Lifetime
- 2000-05-01 EP EP00928611A patent/EP1173210B1/de not_active Expired - Lifetime
- 2000-05-01 CN CNB008070989A patent/CN1179753C/zh not_active Expired - Fee Related
- 2000-05-01 DK DK00928611T patent/DK1173210T3/da active
- 2000-05-01 AU AU46820/00A patent/AU4682000A/en not_active Abandoned
- 2000-05-01 WO PCT/US2000/011643 patent/WO2000066164A1/en not_active Ceased
- 2000-05-01 CA CA002372773A patent/CA2372773A1/en not_active Abandoned
- 2000-05-01 AT AT00928611T patent/ATE275973T1/de not_active IP Right Cessation
- 2000-05-01 HK HK02104868.9A patent/HK1043736B/en not_active IP Right Cessation
- 2000-05-01 JP JP2000615048A patent/JP2002543155A/ja not_active Withdrawn
- 2000-05-01 MX MXPA01011311A patent/MXPA01011311A/es not_active Application Discontinuation
- 2000-05-01 SI SI200030540T patent/SI1173210T1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2226833T3 (es) | 2005-04-01 |
| CN1179753C (zh) | 2004-12-15 |
| DE60013798D1 (de) | 2004-10-21 |
| CN1349415A (zh) | 2002-05-15 |
| WO2000066164A1 (en) | 2000-11-09 |
| AU4682000A (en) | 2000-11-17 |
| EP1173210A1 (de) | 2002-01-23 |
| PT1173210E (pt) | 2005-01-31 |
| SI1173210T1 (en) | 2005-02-28 |
| DK1173210T3 (da) | 2005-01-24 |
| DE60013798T2 (de) | 2005-09-29 |
| EP1173210B1 (de) | 2004-09-15 |
| JP2002543155A (ja) | 2002-12-17 |
| CA2372773A1 (en) | 2000-11-09 |
| HK1043736A1 (en) | 2002-09-27 |
| HK1043736B (en) | 2005-04-01 |
| WO2000066164A8 (en) | 2001-05-03 |
| MXPA01011311A (es) | 2003-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1173210 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |