ATE275987T1 - Biokompatible medizinische artikel und verfahren zu deren herstellung - Google Patents
Biokompatible medizinische artikel und verfahren zu deren herstellungInfo
- Publication number
- ATE275987T1 ATE275987T1 AT00979771T AT00979771T ATE275987T1 AT E275987 T1 ATE275987 T1 AT E275987T1 AT 00979771 T AT00979771 T AT 00979771T AT 00979771 T AT00979771 T AT 00979771T AT E275987 T1 ATE275987 T1 AT E275987T1
- Authority
- AT
- Austria
- Prior art keywords
- organopolysiloxane
- heparin
- article
- blood
- adherent
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 4
- 239000008280 blood Substances 0.000 abstract 4
- 210000004369 blood Anatomy 0.000 abstract 4
- 229960002897 heparin Drugs 0.000 abstract 4
- 229920000669 heparin Polymers 0.000 abstract 4
- 229920001296 polysiloxane Polymers 0.000 abstract 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 230000001464 adherent effect Effects 0.000 abstract 2
- 125000000129 anionic group Chemical group 0.000 abstract 2
- 125000002091 cationic group Chemical group 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- -1 poly(ethylene glycol) Polymers 0.000 abstract 2
- 239000000919 ceramic Substances 0.000 abstract 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical compound [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- SNMVRZFUUCLYTO-UHFFFAOYSA-N n-propyl chloride Chemical compound CCCCl SNMVRZFUUCLYTO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000004033 plastic Substances 0.000 abstract 1
- 229920003023 plastic Polymers 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0017—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a surface active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31652—Of asbestos
- Y10T428/31663—As siloxane, silicone or silane
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9928071.1A GB9928071D0 (en) | 1999-11-29 | 1999-11-29 | Blood compatible medical articles |
| PCT/GB2000/004538 WO2001039814A1 (en) | 1999-11-29 | 2000-11-29 | Biocompatible medical articles and process for their production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275987T1 true ATE275987T1 (de) | 2004-10-15 |
Family
ID=10865270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00979771T ATE275987T1 (de) | 1999-11-29 | 2000-11-29 | Biokompatible medizinische artikel und verfahren zu deren herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6756125B2 (de) |
| EP (1) | EP1233796B1 (de) |
| JP (1) | JP4976632B2 (de) |
| AT (1) | ATE275987T1 (de) |
| AU (1) | AU771243B2 (de) |
| CA (1) | CA2399756C (de) |
| DE (1) | DE60013890T2 (de) |
| DK (1) | DK1233796T3 (de) |
| GB (1) | GB9928071D0 (de) |
| WO (1) | WO2001039814A1 (de) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US6862465B2 (en) | 1997-03-04 | 2005-03-01 | Dexcom, Inc. | Device and method for determining analyte levels |
| US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| AU2002309528A1 (en) | 2001-04-02 | 2002-10-15 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
| US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
| US6702857B2 (en) * | 2001-07-27 | 2004-03-09 | Dexcom, Inc. | Membrane for use with implantable devices |
| US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
| US7828728B2 (en) | 2003-07-25 | 2010-11-09 | Dexcom, Inc. | Analyte sensor |
| US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US20060258761A1 (en) * | 2002-05-22 | 2006-11-16 | Robert Boock | Silicone based membranes for use in implantable glucose sensors |
| US7134999B2 (en) * | 2003-04-04 | 2006-11-14 | Dexcom, Inc. | Optimized sensor geometry for an implantable glucose sensor |
| US7875293B2 (en) * | 2003-05-21 | 2011-01-25 | Dexcom, Inc. | Biointerface membranes incorporating bioactive agents |
| EP1648298A4 (de) | 2003-07-25 | 2010-01-13 | Dexcom Inc | Sauerstoffverbessernde membransysteme für implantierbare vorrichtungen |
| US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US8282549B2 (en) | 2003-12-09 | 2012-10-09 | Dexcom, Inc. | Signal processing for continuous analyte sensor |
| US8845536B2 (en) | 2003-08-01 | 2014-09-30 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20070208245A1 (en) * | 2003-08-01 | 2007-09-06 | Brauker James H | Transcutaneous analyte sensor |
| US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8160669B2 (en) | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US9135402B2 (en) * | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US20050090607A1 (en) * | 2003-10-28 | 2005-04-28 | Dexcom, Inc. | Silicone composition for biocompatible membrane |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US20070112291A1 (en) * | 2003-11-26 | 2007-05-17 | Sinu Shunt A/S | Shunt system with coating and flow restricting component exerting a passive and essentially constant resistance to outflow |
| US7550444B2 (en) * | 2004-03-26 | 2009-06-23 | Surmodics, Inc. | Composition and method for preparing biocompatible surfaces |
| JP2007530173A (ja) * | 2004-03-26 | 2007-11-01 | サーモディクス,インコーポレイティド | 生体適合性表面のための方法およびシステム |
| US8277713B2 (en) | 2004-05-03 | 2012-10-02 | Dexcom, Inc. | Implantable analyte sensor |
| US20050245799A1 (en) * | 2004-05-03 | 2005-11-03 | Dexcom, Inc. | Implantable analyte sensor |
| US8886272B2 (en) | 2004-07-13 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| US8989833B2 (en) | 2004-07-13 | 2015-03-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8565848B2 (en) | 2004-07-13 | 2013-10-22 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20070045902A1 (en) * | 2004-07-13 | 2007-03-01 | Brauker James H | Analyte sensor |
| US8452368B2 (en) | 2004-07-13 | 2013-05-28 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20080242961A1 (en) * | 2004-07-13 | 2008-10-02 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7452412B2 (en) * | 2004-08-24 | 2008-11-18 | Midwest Research Institute, Inc. | High-efficiency filter device and method for making same |
| JP2006161020A (ja) * | 2004-11-15 | 2006-06-22 | Jsr Corp | 熱可塑性エラストマー成形品、熱可塑性エラストマー成形品の表面処理方法、医療用チューブ、および輸液セット |
| US8744546B2 (en) | 2005-05-05 | 2014-06-03 | Dexcom, Inc. | Cellulosic-based resistance domain for an analyte sensor |
| US8060174B2 (en) | 2005-04-15 | 2011-11-15 | Dexcom, Inc. | Analyte sensing biointerface |
| WO2007143225A2 (en) | 2006-06-07 | 2007-12-13 | Abbott Diabetes Care, Inc. | Analyte monitoring system and method |
| ATE416526T1 (de) * | 2006-08-25 | 2008-12-15 | Alcatel Lucent | Digitalsignalempfänger mit q-faktorüberwachung |
| US8114465B2 (en) * | 2007-04-02 | 2012-02-14 | Ension, Inc. | Process for preparing a substrate coated with a biomolecule |
| US9693841B2 (en) | 2007-04-02 | 2017-07-04 | Ension, Inc. | Surface treated staples, sutures and dental floss and methods of manufacturing the same |
| US20200037875A1 (en) | 2007-05-18 | 2020-02-06 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US8290559B2 (en) | 2007-12-17 | 2012-10-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| CN102047101A (zh) * | 2008-03-28 | 2011-05-04 | 德克斯康公司 | 用于连续的分析物传感器的聚合物膜 |
| US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| EP4549933A3 (de) | 2008-09-19 | 2025-05-21 | DexCom, Inc. | Partikelhaltige membran und partikelelektrode für analytsensoren |
| KR101100987B1 (ko) * | 2010-03-23 | 2011-12-30 | 삼성모바일디스플레이주식회사 | 터치 스크린 패널 |
| EP2484388A1 (de) | 2011-02-05 | 2012-08-08 | MaRVis Technologies GmbH | Implantierbare oder einsetzbare, mittels MRT erkennbare medizinische Vorrichtung mit einer Beschichtung, die paramagnetische Ionen umfasst, und Verfahren zu deren Herstellung |
| KR20140023286A (ko) * | 2011-06-24 | 2014-02-26 | 칸지 이노우에 | 유리 혈전 포획 기구 |
| EP2692365A1 (de) | 2012-08-03 | 2014-02-05 | MaRVis Medical GmbH | Implantierbare oder einsetzbare, mittels MRT erkennbare medizinische Vorrichtung mit einer Beschichtung, die paramagnetische Ionen umfasst, und Verfahren zu deren Herstellung |
| JP7080050B2 (ja) * | 2017-12-28 | 2022-06-03 | ユニ・チャーム株式会社 | パンツ型吸収性物品 |
| JP7080051B2 (ja) * | 2017-12-28 | 2022-06-03 | ユニ・チャーム株式会社 | パンツ型吸収性物品 |
| EP3781222A4 (de) * | 2018-04-20 | 2022-01-26 | Ension, Inc. | Manipulierte bioaktive heparinmatrix für die klinische anwendung einer blutkontaktoberfläche und verfahren zu ihrer herstellung |
| CN121648353A (zh) | 2019-03-19 | 2026-03-13 | 杰美特涂层科技(厦门)有限公司 | 一种包含共价键合的肝素涂层的医疗装置的制备方法 |
| CN111760107A (zh) * | 2020-07-08 | 2020-10-13 | 北京化工大学 | 一种高效气液交换的膜式氧合器 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1669955B1 (de) | 1966-04-11 | 1970-10-22 | Dow Corning | Antikoagulative Behandlung von Substratoberflaechen |
| JPS6145765A (ja) * | 1984-08-07 | 1986-03-05 | 宇部興産株式会社 | 血管補綴物及びその製造方法 |
| JPH0611305B2 (ja) * | 1985-07-29 | 1994-02-16 | 株式会社高研 | 抗血栓性材料の製造方法 |
| JPS6346163A (ja) * | 1986-04-15 | 1988-02-27 | 株式会社資生堂 | 外用部材 |
| US5013717A (en) * | 1988-04-18 | 1991-05-07 | Becton, Dickinson And Company | Blood compatible, lubricious article and composition and method therefor |
| US5182317A (en) * | 1988-06-08 | 1993-01-26 | Cardiopulmonics, Inc. | Multifunctional thrombo-resistant coatings and methods of manufacture |
| EP0495478B1 (de) * | 1991-01-16 | 1999-04-21 | Toyo Boseki Kabushiki Kaisha | Blutverträgliches Material |
| WO1992021387A1 (en) * | 1991-05-31 | 1992-12-10 | Baxter International Inc. | Thromboresistant coating for defoaming applications |
| US6119028A (en) * | 1997-10-20 | 2000-09-12 | Alfred E. Mann Foundation | Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces |
| EP0930331A3 (de) * | 1998-01-14 | 2000-05-17 | Degussa-Hüls Aktiengesellschaft | Bioaktive und hydrophile Beschichtung von polymeren Substraten |
| US6024918A (en) * | 1998-03-13 | 2000-02-15 | Medtronic, Inc. | Method for attachment of biomolecules to surfaces of medical devices |
-
1999
- 1999-11-29 GB GBGB9928071.1A patent/GB9928071D0/en not_active Ceased
-
2000
- 2000-11-29 AT AT00979771T patent/ATE275987T1/de active
- 2000-11-29 JP JP2001541544A patent/JP4976632B2/ja not_active Expired - Fee Related
- 2000-11-29 WO PCT/GB2000/004538 patent/WO2001039814A1/en not_active Ceased
- 2000-11-29 DE DE60013890T patent/DE60013890T2/de not_active Expired - Lifetime
- 2000-11-29 DK DK00979771T patent/DK1233796T3/da active
- 2000-11-29 AU AU17163/01A patent/AU771243B2/en not_active Ceased
- 2000-11-29 EP EP00979771A patent/EP1233796B1/de not_active Expired - Lifetime
- 2000-11-29 CA CA2399756A patent/CA2399756C/en not_active Expired - Fee Related
- 2000-11-29 US US10/148,709 patent/US6756125B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001039814A9 (en) | 2001-11-22 |
| AU771243B2 (en) | 2004-03-18 |
| JP4976632B2 (ja) | 2012-07-18 |
| AU1716301A (en) | 2001-06-12 |
| US20030059631A1 (en) | 2003-03-27 |
| DE60013890D1 (de) | 2004-10-21 |
| EP1233796A1 (de) | 2002-08-28 |
| CA2399756A1 (en) | 2001-06-07 |
| DE60013890T2 (de) | 2005-09-29 |
| EP1233796B1 (de) | 2004-09-15 |
| WO2001039814A1 (en) | 2001-06-07 |
| JP2003520630A (ja) | 2003-07-08 |
| GB9928071D0 (en) | 2000-01-26 |
| US6756125B2 (en) | 2004-06-29 |
| CA2399756C (en) | 2010-07-13 |
| DK1233796T3 (da) | 2004-11-29 |
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