ATE276262T1 - Oxazinochinolone für die behandlung viraler infektionen - Google Patents

Oxazinochinolone für die behandlung viraler infektionen

Info

Publication number
ATE276262T1
ATE276262T1 AT01948231T AT01948231T ATE276262T1 AT E276262 T1 ATE276262 T1 AT E276262T1 AT 01948231 T AT01948231 T AT 01948231T AT 01948231 T AT01948231 T AT 01948231T AT E276262 T1 ATE276262 T1 AT E276262T1
Authority
AT
Austria
Prior art keywords
oxazinoquinolones
treatment
viral infections
infections
viral
Prior art date
Application number
AT01948231T
Other languages
English (en)
Inventor
Suvit Thaisrivongs
Steven R Turner
Atli Thorarensen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE276262T1 publication Critical patent/ATE276262T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT01948231T 2000-07-12 2001-06-29 Oxazinochinolone für die behandlung viraler infektionen ATE276262T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21755500P 2000-07-12 2000-07-12
US26221101P 2001-01-17 2001-01-17
US26825501P 2001-02-13 2001-02-13
PCT/US2001/016507 WO2002004462A1 (en) 2000-07-12 2001-06-29 Oxazinoquinolones useful for the treatment of viral infections

Publications (1)

Publication Number Publication Date
ATE276262T1 true ATE276262T1 (de) 2004-10-15

Family

ID=27396428

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01948231T ATE276262T1 (de) 2000-07-12 2001-06-29 Oxazinochinolone für die behandlung viraler infektionen

Country Status (11)

Country Link
EP (1) EP1299395B1 (de)
JP (1) JP2004502777A (de)
AR (1) AR030304A1 (de)
AT (1) ATE276262T1 (de)
AU (1) AU2001269704A1 (de)
DE (1) DE60105614T2 (de)
ES (1) ES2227232T3 (de)
PE (1) PE20020189A1 (de)
PT (1) PT1299395E (de)
TR (1) TR200402534T4 (de)
WO (1) WO2002004462A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6821969B2 (en) 2001-02-13 2004-11-23 Pharmacia & Upjohn Company Thioxazinoquinolones as antiviral agents
BRPI0409105A (pt) * 2003-04-07 2006-04-25 Cylene Pharmaceuticals Inc análogos de quinobenzoxazina substituìdos
CA2645376C (en) 2006-03-13 2017-06-20 Activx Biosciences, Inc. Aminoquinolones as gsk-3 inhibitors
CN102351880B (zh) 2007-09-11 2014-11-12 杏林制药株式会社 作为gsk-3 抑制剂的氰基氨基喹诺酮和四唑并氨基喹诺酮
US8476261B2 (en) 2007-09-12 2013-07-02 Kyorin Pharmaceutical Co., Ltd. Spirocyclic aminoquinolones as GSK-3 inhibitors
MX2011009414A (es) 2009-03-11 2011-10-19 Kyorin Seiyaku Kk 7-cicloalquiloaminoquinolonas como inhibidores de gsk-3.
US9290476B2 (en) 2012-10-16 2016-03-22 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
CN104884448A (zh) 2012-10-16 2015-09-02 詹森药业有限公司 Rorγt的杂芳基连接的喹啉基调节剂
CN105073729A (zh) 2012-10-16 2015-11-18 詹森药业有限公司 RORγt的苯基连接的喹啉基调节剂
US9221804B2 (en) 2013-10-15 2015-12-29 Janssen Pharmaceutica Nv Secondary alcohol quinolinyl modulators of RORγt
US10555941B2 (en) 2013-10-15 2020-02-11 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of RORγt
US9328095B2 (en) 2013-10-15 2016-05-03 Janssen Pharmaceutica Nv Heteroaryl linked quinolinyl modulators of RORgammat
BR112016008258A2 (pt) 2013-10-15 2017-10-10 Janssen Pharmaceutica Nv moduladores de ror?t de quinolinila
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
BR112016008215A2 (pt) 2013-10-15 2017-09-26 Janssen Pharmaceutica Nv moduladores de quinolinila ligados por alquila de roryt
US9403816B2 (en) 2013-10-15 2016-08-02 Janssen Pharmaceutica Nv Phenyl linked quinolinyl modulators of RORγt
CA3112326A1 (en) 2018-09-12 2020-03-19 Novartis Ag Antiviral pyridopyrazinedione compounds
KR20250127350A (ko) 2019-09-26 2025-08-26 노파르티스 아게 항바이러스성 피라졸로피리디논 화합물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959363A (en) * 1989-06-23 1990-09-25 Sterling Drug Inc. Quinolonecarboxamide compounds, their preparation and use as antivirals.
US5792774A (en) * 1996-02-21 1998-08-11 Chiroscience Limited Quinolones and their therapeutic use
AU2657499A (en) * 1998-02-04 1999-08-23 Board Of Regents, The University Of Texas System Synthesis of quinobenzoxazine analogues with topoisomerase ii and quadruplex interactions for use as antineoplastic agents
US6248739B1 (en) * 1999-01-08 2001-06-19 Pharmacia & Upjohn Company Quinolinecarboxamides as antiviral agents
TW500724B (en) * 1999-10-05 2002-09-01 Pharmacia & Amp Upjohn Company Oxazinoquinolones useful for the treatment of viral infections

Also Published As

Publication number Publication date
ES2227232T3 (es) 2005-04-01
WO2002004462A1 (en) 2002-01-17
JP2004502777A (ja) 2004-01-29
DE60105614T2 (de) 2005-10-06
AR030304A1 (es) 2003-08-20
AU2001269704A1 (en) 2002-01-21
EP1299395B1 (de) 2004-09-15
PT1299395E (pt) 2005-01-31
TR200402534T4 (tr) 2004-12-21
EP1299395A1 (de) 2003-04-09
PE20020189A1 (es) 2002-03-02
DE60105614D1 (de) 2004-10-21

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