ATE277386T1 - Verfahren zum screening von chemischen verbindungen - Google Patents

Verfahren zum screening von chemischen verbindungen

Info

Publication number
ATE277386T1
ATE277386T1 AT00978287T AT00978287T ATE277386T1 AT E277386 T1 ATE277386 T1 AT E277386T1 AT 00978287 T AT00978287 T AT 00978287T AT 00978287 T AT00978287 T AT 00978287T AT E277386 T1 ATE277386 T1 AT E277386T1
Authority
AT
Austria
Prior art keywords
chemical compounds
screening chemical
methods
assays
rates
Prior art date
Application number
AT00978287T
Other languages
English (en)
Inventor
Timothy D Harris
Richard L Hansen
William Karsh
Neal A Nicklaus
Jay K Trautman
Original Assignee
Amersham Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21741940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE277386(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham Biosciences Corp filed Critical Amersham Biosciences Corp
Application granted granted Critical
Publication of ATE277386T1 publication Critical patent/ATE277386T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/11—Region-based segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/187—Segmentation; Edge detection involving region growing; involving region merging; involving connected component labelling
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/194—Segmentation; Edge detection involving foreground-background segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/60—Analysis of geometric attributes
    • G06T7/62—Analysis of geometric attributes of area, perimeter, diameter or volume
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Geometry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Multimedia (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT00978287T 2000-10-27 2000-10-27 Verfahren zum screening von chemischen verbindungen ATE277386T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/029776 WO2002035474A1 (en) 2000-10-27 2000-10-27 Method and apparatus for screening chemical compounds

Publications (1)

Publication Number Publication Date
ATE277386T1 true ATE277386T1 (de) 2004-10-15

Family

ID=21741940

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00978287T ATE277386T1 (de) 2000-10-27 2000-10-27 Verfahren zum screening von chemischen verbindungen

Country Status (6)

Country Link
EP (1) EP1330787B1 (de)
AT (1) ATE277386T1 (de)
AU (1) AU1576401A (de)
CA (1) CA2426798C (de)
DE (1) DE60014188T2 (de)
WO (1) WO2002035474A1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7450229B2 (en) 1999-01-25 2008-11-11 Amnis Corporation Methods for analyzing inter-cellular phenomena
US8406498B2 (en) 1999-01-25 2013-03-26 Amnis Corporation Blood and cell analysis using an imaging flow cytometer
US8131053B2 (en) 1999-01-25 2012-03-06 Amnis Corporation Detection of circulating tumor cells using imaging flow cytometry
US8885913B2 (en) 1999-01-25 2014-11-11 Amnis Corporation Detection of circulating tumor cells using imaging flow cytometry
US7907765B2 (en) 2001-03-28 2011-03-15 University Of Washington Focal plane tracking for optical microtomography
US6636623B2 (en) * 2001-08-10 2003-10-21 Visiongate, Inc. Optical projection imaging system and method for automatically detecting cells with molecular marker compartmentalization associated with malignancy and disease
US7738945B2 (en) 2002-04-19 2010-06-15 University Of Washington Method and apparatus for pseudo-projection formation for optical tomography
US7260253B2 (en) 2002-04-19 2007-08-21 Visiongate, Inc. Method for correction of relative object-detector motion between successive views
WO2004099773A1 (en) * 2003-04-30 2004-11-18 Pfizer Products Inc. Automated in vitro cellular imaging assays for micronuclei and other target objects
US20050046848A1 (en) 2003-08-26 2005-03-03 Blueshift Biotechnologies, Inc. Time dependent fluorescence measurements
WO2005098430A2 (en) * 2004-03-16 2005-10-20 Amnis Corporation Image based quantitation of molecular translocation
US8953866B2 (en) 2004-03-16 2015-02-10 Amnis Corporation Method for imaging and differential analysis of cells
US7141378B2 (en) 2004-07-02 2006-11-28 Blueshift Biotechnologies, Inc. Exploring fluorophore microenvironments
US7582634B2 (en) 2005-02-18 2009-09-01 Wyeth 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7534796B2 (en) 2005-02-18 2009-05-19 Wyeth Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7538113B2 (en) 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7531542B2 (en) 2005-05-18 2009-05-12 Wyeth Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
US7582636B2 (en) 2005-05-26 2009-09-01 Wyeth Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
US7835561B2 (en) 2007-05-18 2010-11-16 Visiongate, Inc. Method for image processing and reconstruction of images for optical tomography
US7787112B2 (en) * 2007-10-22 2010-08-31 Visiongate, Inc. Depth of field extension for optical tomography
AU2008318230A1 (en) * 2007-10-29 2009-05-07 National Research Council Of Canada Method and apparatus for detecting fluorescence emitted by particle-bound fluorophores confined by particle traps
US8143600B2 (en) 2008-02-18 2012-03-27 Visiongate, Inc. 3D imaging of live cells with ultraviolet radiation
US9915813B2 (en) 2009-12-04 2018-03-13 Koninklijke Philips N.V. System and method for time-related microscopy of biological organisms
FR2969292A1 (fr) * 2010-12-17 2012-06-22 Commissariat Energie Atomique Procede et dispositif pour examen optique en geometrie de reflexion
EP2849752B1 (de) * 2012-10-26 2018-02-21 Canon Kabushiki Kaisha Krebszellenhemmendes arzneimittel und sonde für den nachweis von krebsstammzellen
US11069054B2 (en) 2015-12-30 2021-07-20 Visiongate, Inc. System and method for automated detection and monitoring of dysplasia and administration of immunotherapy and chemotherapy
CN108519329B (zh) * 2018-03-26 2021-01-15 华中科技大学 一种多路扫描与探测的线共聚焦成像装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5774573A (en) * 1984-12-20 1998-06-30 Orbotech Ltd. Automatic visual inspection system
US4751643A (en) 1986-08-04 1988-06-14 General Electric Company Method and apparatus for determining connected substructures within a body
EP0610916A3 (de) * 1993-02-09 1994-10-12 Cedars Sinai Medical Center Verfahren und Vorrichtung zur Erzeugung vorzugsweiser segmentierter numerischer Bilder.
US5604819A (en) * 1993-03-15 1997-02-18 Schlumberger Technologies Inc. Determining offset between images of an IC
JPH07299053A (ja) * 1994-04-29 1995-11-14 Arch Dev Corp コンピュータ診断支援方法
US5892854A (en) * 1997-01-21 1999-04-06 Xerox Corporation Automatic image registration using binary moments
KR100560588B1 (ko) * 1998-03-16 2006-03-16 에머샘 바이오사이언시즈 코프 공초점 마이크로스코피 영상 시스템
JP3840025B2 (ja) * 1999-03-19 2006-11-01 日本無線株式会社 画像処理方法

Also Published As

Publication number Publication date
DE60014188T2 (de) 2005-11-17
CA2426798A1 (en) 2002-05-02
CA2426798C (en) 2012-02-21
EP1330787B1 (de) 2004-09-22
EP1330787A1 (de) 2003-07-30
WO2002035474A1 (en) 2002-05-02
WO2002035474A9 (en) 2006-05-18
DE60014188D1 (de) 2004-10-28
AU1576401A (en) 2002-05-06

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