ATE277634T1 - Assembly-defizientes herpesvirus als impfstoff - Google Patents

Assembly-defizientes herpesvirus als impfstoff

Info

Publication number
ATE277634T1
ATE277634T1 AT97937214T AT97937214T ATE277634T1 AT E277634 T1 ATE277634 T1 AT E277634T1 AT 97937214 T AT97937214 T AT 97937214T AT 97937214 T AT97937214 T AT 97937214T AT E277634 T1 ATE277634 T1 AT E277634T1
Authority
AT
Austria
Prior art keywords
assembly
vaccine
deficiency
herpes virus
herpesvirus
Prior art date
Application number
AT97937214T
Other languages
English (en)
Inventor
Paul J Hippenmeyer
Anne M Rankin
Verne A Luckow
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE277634T1 publication Critical patent/ATE277634T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT97937214T 1996-07-26 1997-07-25 Assembly-defizientes herpesvirus als impfstoff ATE277634T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/687,820 US5972666A (en) 1996-07-26 1996-07-26 Assembly-deficient herpesvirus vaccine
PCT/US1997/014192 WO1998004286A2 (en) 1996-07-26 1997-07-25 Assembly-deficient herpesvirus vaccine

Publications (1)

Publication Number Publication Date
ATE277634T1 true ATE277634T1 (de) 2004-10-15

Family

ID=24761993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97937214T ATE277634T1 (de) 1996-07-26 1997-07-25 Assembly-defizientes herpesvirus als impfstoff

Country Status (14)

Country Link
US (1) US5972666A (de)
EP (1) EP0956045B1 (de)
JP (1) JP2000516597A (de)
CN (1) CN1230893A (de)
AT (1) ATE277634T1 (de)
AU (1) AU3977997A (de)
BR (1) BR9710604A (de)
CA (1) CA2261071A1 (de)
CZ (1) CZ17999A3 (de)
DE (1) DE69730993T2 (de)
DK (1) DK0956045T3 (de)
ES (1) ES2231884T3 (de)
PT (1) PT956045E (de)
WO (1) WO1998004286A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2360942A1 (en) * 1999-02-04 2000-08-10 Jorn Bullerdiek Preparations for preventing and/or treating a tissue change of mesenchymal origin
US6291226B1 (en) * 1999-02-25 2001-09-18 National Research Council Of Canada Adenovirus mutants with deleted protease gene
WO2001017553A1 (en) * 1999-09-10 2001-03-15 Akzo Nobel N.V. Equine herpes virus temperature sensitive mutant and live vaccine thereof
WO2001078776A1 (en) * 2000-04-13 2001-10-25 Avant Immunotherapeutics, Inc. Herpes virus complementing cell line
ATE499948T1 (de) * 2001-01-12 2011-03-15 Novartis Vaccines & Diagnostic Nukleinsäure mukosale immunisierung
US7968298B2 (en) * 2001-03-28 2011-06-28 The United States Of America As Represented By The Department Of Health And Human Services Use of herpesviruses, herpesvirus proteins and nucleic acids encoding the proteins to inhibit CCR5-tropic HIV-1 infection and replication
JP3923505B2 (ja) * 2003-08-29 2007-06-06 株式会社ウイルス医科学研究所 Ｈｈｖ−６由来の組換ウイルスベクター、その製造方法、それを用いた宿主細胞の形質転換方法、それにより形質転換された宿主細胞およびそれを用いた遺伝子治療方法
US20080089910A1 (en) * 2004-06-29 2008-04-17 Visalli Et Al Attenuated Herpes Simplex Virus Type-2, Vectors Thereof and Immunogenic Compositions Thereof
EP2521786B1 (de) 2006-07-20 2015-06-24 Vical Incorporated Zusammensetzungen zur impfung gegen hsv-2
CN111117974B (zh) * 2019-12-20 2022-02-22 华南农业大学 一种可视化绿色荧光猪伪狂犬病毒及其构建方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9102126D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Biolog Novel vaccine
JPH05236967A (ja) * 1991-05-07 1993-09-17 Medical Res Council ヘルペスウイルス粒子及びワクチン
WO1996012007A1 (en) * 1994-10-17 1996-04-25 Merck & Co., Inc. Stable recombinant hcmv protease
US5728557A (en) * 1995-06-01 1998-03-17 Merck & Co., Inc. Method of making herpes simplex type 1 mutants and mutants so produced

Also Published As

Publication number Publication date
CA2261071A1 (en) 1998-02-05
WO1998004286A3 (en) 1998-05-14
CN1230893A (zh) 1999-10-06
DE69730993T2 (de) 2005-10-06
AU3977997A (en) 1998-02-20
DK0956045T3 (da) 2005-01-24
EP0956045A2 (de) 1999-11-17
US5972666A (en) 1999-10-26
WO1998004286A2 (en) 1998-02-05
PT956045E (pt) 2005-01-31
CZ17999A3 (cs) 1999-07-14
EP0956045B1 (de) 2004-09-29
ES2231884T3 (es) 2005-05-16
DE69730993D1 (de) 2004-11-04
JP2000516597A (ja) 2000-12-12
BR9710604A (pt) 1999-08-17

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