ATE277942T1 - Pseudopeptide mit inhibierender wirkung auf protein-tyrosinkinasen und sie enthaltende pharmazeutische zusammensetzungen - Google Patents
Pseudopeptide mit inhibierender wirkung auf protein-tyrosinkinasen und sie enthaltende pharmazeutische zusammensetzungenInfo
- Publication number
- ATE277942T1 ATE277942T1 AT99962285T AT99962285T ATE277942T1 AT E277942 T1 ATE277942 T1 AT E277942T1 AT 99962285 T AT99962285 T AT 99962285T AT 99962285 T AT99962285 T AT 99962285T AT E277942 T1 ATE277942 T1 AT E277942T1
- Authority
- AT
- Austria
- Prior art keywords
- pseudopeptides
- pharmaceutical compositions
- compositions containing
- tyrosine kinases
- protein tyrosine
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 title 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- -1 3-pyridinylmethyl Chemical group 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000005119 alkyl cycloalkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004923 naphthylmethyl group Chemical group C1(=CC=CC2=CC=CC=C12)C* 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9816459A FR2787793B1 (fr) | 1998-12-24 | 1998-12-24 | Composes pseudopeptidiques dotes d'une activite inhibitrice a l'egard des voies activees par les proteines a activite tyrosine kinase et les compositions pharmaceutiques les contenant |
| PCT/FR1999/003289 WO2000039153A1 (fr) | 1998-12-24 | 1999-12-24 | Composes pseudopeptidiques dotes d'une activite inhibitrice a l'egard des voies activees par les proteines a activite tyrosine kinase et les compositions pharmaceutiques les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE277942T1 true ATE277942T1 (de) | 2004-10-15 |
Family
ID=9534521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99962285T ATE277942T1 (de) | 1998-12-24 | 1999-12-24 | Pseudopeptide mit inhibierender wirkung auf protein-tyrosinkinasen und sie enthaltende pharmazeutische zusammensetzungen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1140980B1 (de) |
| AT (1) | ATE277942T1 (de) |
| CA (1) | CA2356777A1 (de) |
| DE (1) | DE69920748D1 (de) |
| FR (1) | FR2787793B1 (de) |
| WO (1) | WO2000039153A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19933492B4 (de) | 1999-07-16 | 2008-01-10 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Konjugat zur Vermittlung eines zell-, kompartiment- oder membranspezifischen Transports von Wirksubstanzen, Verfahren zu dessen Herstellung und dessen Verwendung |
| CN116813504A (zh) * | 2023-07-10 | 2023-09-29 | 大连民族大学 | 基于两相循环法制备Fmoc氨基酸的工艺 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184205B1 (en) * | 1994-07-22 | 2001-02-06 | University Of North Carolina At Chapel Hill | GRB2 SH3 binding peptides and methods of isolating and using same |
| US6280964B1 (en) * | 1995-04-14 | 2001-08-28 | The Regents Of The University Of California | Binding sites for phosphotyrosine binding domains |
| GB9603227D0 (en) * | 1996-02-15 | 1996-04-17 | Pharmacia Spa | Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use |
-
1998
- 1998-12-24 FR FR9816459A patent/FR2787793B1/fr not_active Expired - Fee Related
-
1999
- 1999-12-24 CA CA002356777A patent/CA2356777A1/fr not_active Abandoned
- 1999-12-24 EP EP19990962285 patent/EP1140980B1/de not_active Expired - Lifetime
- 1999-12-24 DE DE69920748T patent/DE69920748D1/de not_active Expired - Lifetime
- 1999-12-24 AT AT99962285T patent/ATE277942T1/de not_active IP Right Cessation
- 1999-12-24 WO PCT/FR1999/003289 patent/WO2000039153A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69920748D1 (de) | 2004-11-04 |
| FR2787793A1 (fr) | 2000-06-30 |
| EP1140980B1 (de) | 2004-09-29 |
| EP1140980A1 (de) | 2001-10-10 |
| CA2356777A1 (fr) | 2000-07-06 |
| WO2000039153A1 (fr) | 2000-07-06 |
| FR2787793B1 (fr) | 2001-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |