ATE278695T1 - Piperidinderivate - Google Patents
PiperidinderivateInfo
- Publication number
- ATE278695T1 ATE278695T1 AT98965753T AT98965753T ATE278695T1 AT E278695 T1 ATE278695 T1 AT E278695T1 AT 98965753 T AT98965753 T AT 98965753T AT 98965753 T AT98965753 T AT 98965753T AT E278695 T1 ATE278695 T1 AT E278695T1
- Authority
- AT
- Austria
- Prior art keywords
- piperidine derivatives
- piperidine
- derivatives
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical class C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97121844 | 1997-12-11 | ||
| PCT/EP1998/007864 WO1999029696A1 (en) | 1997-12-11 | 1998-12-03 | Piperidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE278695T1 true ATE278695T1 (de) | 2004-10-15 |
Family
ID=8227781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98965753T ATE278695T1 (de) | 1997-12-11 | 1998-12-03 | Piperidinderivate |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6166209A (de) |
| EP (1) | EP1037892B1 (de) |
| JP (1) | JP3453121B2 (de) |
| KR (1) | KR100369689B1 (de) |
| CN (1) | CN1112365C (de) |
| AR (1) | AR016431A1 (de) |
| AT (1) | ATE278695T1 (de) |
| AU (1) | AU744192B2 (de) |
| BR (1) | BR9813543A (de) |
| CA (1) | CA2310458C (de) |
| DE (1) | DE69826891T2 (de) |
| ES (1) | ES2229557T3 (de) |
| PT (1) | PT1037892E (de) |
| TR (1) | TR200001669T2 (de) |
| WO (1) | WO1999029696A1 (de) |
| ZA (1) | ZA9811345B (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI279402B (en) | 1999-08-20 | 2007-04-21 | Banyu Pharma Co Ltd | Spiro compounds having NPY antagonistic activities and agents containing the same |
| US6803372B2 (en) | 1999-08-20 | 2004-10-12 | Banyu Pharmaceutical Co., Ltd. | Spiro compounds |
| US6462053B1 (en) | 1999-08-20 | 2002-10-08 | Banyu Pharmaceutical Co., Ltd. | Spiro compounds |
| US6686370B2 (en) | 1999-12-06 | 2004-02-03 | Euro-Celtique S.A. | Triazospiro compounds having nociceptin receptor affinity |
| AU1816901A (en) | 1999-12-06 | 2001-06-12 | Euro-Celtique S.A. | Benzimidazole compounds having nociceptin receptor affinity |
| US6984664B2 (en) | 1999-12-06 | 2006-01-10 | Euro-Celtique, S.A. | Tertiary amino compounds having opioid receptor affinity |
| US6916822B2 (en) * | 2000-02-18 | 2005-07-12 | Meiji Seika Kaisha, Ltd. | Phenoxyalkylamine derivatives useful as opioid δ receptor agonists |
| JP4489354B2 (ja) | 2001-04-18 | 2010-06-23 | ユーロ−セルティーク エス.エイ. | スピロインデンおよびスピロインダン化合物類 |
| RU2268883C2 (ru) | 2001-04-18 | 2006-01-27 | Эро-Селтик, С.А. | Аналоги ноницептина и фармацевтическая композиция на их основе |
| KR100628292B1 (ko) | 2001-04-18 | 2006-09-27 | 유로-셀티크 소시에떼 아노뉨 | 스파이로파이라졸 화합물 |
| EP1385518B1 (de) | 2001-04-18 | 2008-08-06 | Euro-Celtique S.A. | Benzimidazolon-verbindungen |
| IL158484A0 (en) | 2001-04-18 | 2004-05-12 | Euro Celtique Sa | Nociceptin analogs |
| WO2002088089A1 (en) * | 2001-04-19 | 2002-11-07 | Banyu Pharmaceutical Co., Ltd. | Spiropiperidine derivatives, nociceptin receptor antagonists containing the same as the active ingredient and medicinal compositions |
| WO2002094825A1 (en) * | 2001-05-22 | 2002-11-28 | Banyu Pharmaceutical Co., Ltd. | Novel spiropiperidine derivative |
| US20030078278A1 (en) * | 2001-06-26 | 2003-04-24 | Pfizer Inc. | Spiropiperidine compounds as ligands for ORL-1 receptor |
| JP4056977B2 (ja) | 2002-03-29 | 2008-03-05 | 田辺三菱製薬株式会社 | 睡眠障害治療薬 |
| US20050228023A1 (en) * | 2003-12-19 | 2005-10-13 | Sri International | Agonist and antagonist ligands of the nociceptin receptor |
| US7855294B2 (en) * | 2004-03-05 | 2010-12-21 | Banyu Pharmaceutical Co., Ltd. | Cycloalkanopyridine derivative |
| US8076349B2 (en) | 2004-12-09 | 2011-12-13 | Virochem Pharma Inc. | Spirotropane compounds and methods for the modulation of chemokine receptor activity |
| EA200701248A1 (ru) * | 2004-12-09 | 2007-12-28 | Вирокем Фарма Инк. | Новые спиротропановые соединения и способы модуляции активности рецептора хемокина |
| EP1896479A1 (de) * | 2005-06-17 | 2008-03-12 | Pfizer, Inc. | Alpha-(aryl- oder heteroaryl-methyl)-beta-piperidinopropansäureverbindungen als antagonisten des orl1-rezeptors |
| WO2007028638A1 (en) | 2005-09-09 | 2007-03-15 | Euro-Celtique S.A. | Fused and spirocycle compounds and the use thereof |
| JP2009525269A (ja) * | 2006-01-30 | 2009-07-09 | ユーロ−セルティーク エス.エイ. | カルシウムチャネルブロッカーとしての環状尿素化合物 |
| DE602007006990D1 (de) | 2006-12-07 | 2010-07-15 | Hoffmann La Roche | Spiropiperidinderivate als antagonisten des via-rezeptors |
| BRPI0721138A2 (pt) | 2006-12-22 | 2014-04-01 | Hoffmann La Roche | Derivados de espiro-piperidina |
| CN101563323B (zh) | 2006-12-22 | 2012-07-04 | 弗·哈夫曼-拉罗切有限公司 | 螺-哌啶衍生物 |
| US8728275B2 (en) | 2012-07-27 | 2014-05-20 | Ecolab Usa Inc. | Glycerol-based polymers for reducing deposition of organic contaminants in papermaking processes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3962259A (en) * | 1973-12-12 | 1976-06-08 | American Hoechst Corporation | 1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| CA2226058C (en) * | 1997-01-30 | 2008-01-29 | F. Hoffmann-La Roche Ag | 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives |
-
1998
- 1998-11-20 US US09/196,992 patent/US6166209A/en not_active Expired - Fee Related
- 1998-12-03 BR BR9813543-0A patent/BR9813543A/pt not_active Application Discontinuation
- 1998-12-03 CA CA002310458A patent/CA2310458C/en not_active Expired - Fee Related
- 1998-12-03 AU AU21578/99A patent/AU744192B2/en not_active Ceased
- 1998-12-03 ES ES98965753T patent/ES2229557T3/es not_active Expired - Lifetime
- 1998-12-03 KR KR10-2000-7006304A patent/KR100369689B1/ko not_active Expired - Fee Related
- 1998-12-03 WO PCT/EP1998/007864 patent/WO1999029696A1/en not_active Ceased
- 1998-12-03 TR TR2000/01669T patent/TR200001669T2/xx unknown
- 1998-12-03 JP JP2000524289A patent/JP3453121B2/ja not_active Expired - Lifetime
- 1998-12-03 CN CN98812049A patent/CN1112365C/zh not_active Expired - Fee Related
- 1998-12-03 DE DE69826891T patent/DE69826891T2/de not_active Expired - Lifetime
- 1998-12-03 AT AT98965753T patent/ATE278695T1/de not_active IP Right Cessation
- 1998-12-03 PT PT98965753T patent/PT1037892E/pt unknown
- 1998-12-03 EP EP98965753A patent/EP1037892B1/de not_active Expired - Lifetime
- 1998-12-09 AR ARP980106249A patent/AR016431A1/es unknown
- 1998-12-10 ZA ZA9811345A patent/ZA9811345B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR016431A1 (es) | 2001-07-04 |
| US6166209A (en) | 2000-12-26 |
| JP3453121B2 (ja) | 2003-10-06 |
| AU2157899A (en) | 1999-06-28 |
| TR200001669T2 (tr) | 2001-01-22 |
| AU744192B2 (en) | 2002-02-21 |
| CA2310458A1 (en) | 1999-06-17 |
| EP1037892A1 (de) | 2000-09-27 |
| BR9813543A (pt) | 2000-10-10 |
| KR20010032958A (ko) | 2001-04-25 |
| KR100369689B1 (ko) | 2003-01-30 |
| CN1112365C (zh) | 2003-06-25 |
| PT1037892E (pt) | 2005-01-31 |
| EP1037892B1 (de) | 2004-10-06 |
| DE69826891T2 (de) | 2005-11-24 |
| ZA9811345B (en) | 1999-06-11 |
| ES2229557T3 (es) | 2005-04-16 |
| CN1281459A (zh) | 2001-01-24 |
| JP2001525414A (ja) | 2001-12-11 |
| DE69826891D1 (de) | 2004-11-11 |
| WO1999029696A1 (en) | 1999-06-17 |
| CA2310458C (en) | 2008-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1037892 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |